Thrombocytopoiesis in healthy term newborns.

Abstract:

AIMS:Thrombocytopoiesis was investigated in term newborns determining thrombopoietin (TPO), reticulated platelets (PLRET) and blood platelets (PLT) in relation to gender. PATIENTS AND METHODS:The study was undertaken on 72 healthy term newborns, 33 girls and 39 boys. They fitted all criteria for healthy term newborns. Blood was collected from the umbilical vein immediately after cutting the umbilical cord. The evaluation of thrombocytopoiesis was performed by the following methods: TPO-Quantikine human TPO kit, PLRET- Retic-Count kit, PLT- Advia 120 hematology System. RESULTS:Concentrations of TPO and percentages of reticulated platelets were greater in the female group than in the male group. The changes were not statistically significant, perhaps as a result of the very wide range of parameters tested. The blood platelet count was higher in female newborns than in male newborns, P<0.001. CONCLUSION:The data may indicate that thrombocytopoiesis is more active in female than in male newborns.

journal_name

J Perinat Med

authors

Wasiluk A

doi

10.1515/JPM.2005.046

keywords:

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

252-4

issue

3

eissn

0300-5577

issn

1619-3997

journal_volume

33

pub_type

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