Abstract:
OBJECTIVES:to assess the relationship between maternal and umbilical serum concentrations of matrix metalloproteinases (MMP)-2,8,9, the soluble receptor for advanced glycation end products (sRAGE) and IL-10 and premature delivery and fetal inflammation. METHODS:maternal serum levels of MMPs, sRAGE, IL-10 and C-reactive protein (CRP) were determined in 67 women with preterm labor and in 38 healthy pregnant women of similar gestational age (GA). In the group with preterm labor we also determined umbilical concentrations of MMPs, IL-6 and sRAGE. The group with preterm labor was additionally divided based on the presence of funisitis and elevations of fetal umbilical IL-6 concentrations. RESULTS:maternal serum levels of MMP-2 and sRAGE were significantly lower in women with preterm labor compared to women with normal pregnancy. Additionally, within the group of women with preterm labor, maternal serum MMP-2 concentrations were significantly lower in the subgroup with funisitis and in the subgroup with elevated umbilical concentration of IL-6. CONCLUSION:our results demonstrate significantly different serum concentrations of MMP-2 and sRAGE in women with preterm labor compared to healthy pregnant patients of the same GA.
journal_name
J Perinat Medjournal_title
Journal of perinatal medicineauthors
Koucký M,Germanová A,Kalousová M,Hill M,Cindrová-Davies T,Pařízek A,Svarcová J,Zima T,Hájek Zdoi
10.1515/jpm.2010.092subject
Has Abstractpub_date
2010-11-01 00:00:00pages
589-96issue
6eissn
0300-5577issn
1619-3997journal_volume
38pub_type
杂志文章abstract:OBJECTIVE:To evaluate the effect on perinatal outcome of replacing glucose measurements for the diagnosis of gestational diabetes mellitus in central laboratories with those obtained by portable glucose meter. STUDY DESIGN:Simultaneously, venous blood samples were taken at the 100-g glucose tolerance test, and finger ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2003.019
更新日期:2003-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2009.015
更新日期:2009-01-01 00:00:00
abstract:AIM:To determine acceptance of pregnant women to undergo fetal magnetic resonance imaging (MRI) examination in research and clinical setting. METHODS:A prospective study included a research group [part of a study comparing brain ultrasound (US) to MRI in fetuses at risk for acquired brain damage] and a clinical group ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
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更新日期:2018-11-27 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2006.026
更新日期:2006-01-01 00:00:00
abstract::Background Sjögren's syndrome (SS) is an autoimmune connective tissue disease affecting the body's moisture-producing glands. Some studies have linked SS to adverse maternal/neonatal outcomes, but sample sizes have tended to be small, with few outcomes examined. The purpose of this study was to evaluate the effect of ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2019-0034
更新日期:2019-08-27 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2007.060
更新日期:2007-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2007-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.1999.002
更新日期:1999-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
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更新日期:1980-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2020-0399
更新日期:2020-11-26 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2005.068
更新日期:2005-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2000.060
更新日期:2000-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2003.060
更新日期:2003-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2011-0253
更新日期:2012-03-29 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2001.035
更新日期:2001-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.087
更新日期:2010-09-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2016-0373
更新日期:2018-02-23 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1996.24.2.141
更新日期:1996-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1996.24.5.495
更新日期:1996-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2017-0311
更新日期:2018-10-25 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1975.3.2.105
更新日期:1975-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1983.11.4.187
更新日期:1983-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1989.17.3.221
更新日期:1989-01-01 00:00:00
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
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更新日期:2011-07-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1996.24.6.661
更新日期:1996-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1515/jpm-2015-0361
更新日期:2016-10-01 00:00:00