Evaluation of C. reactive protein values in neonatal sepsis.

Abstract:

:C. reactive protein (CRP) estimations were performed prospectively on 30 consecutive admissions of very low birth weight infants to a Regional neonatal intensive care unit. The samples were analysed by a recently described, rapid intralipid agglutination assay and by a reference turbidimetric technique. Two hundred and ninety samples were assayed by both techniques. The intralipid agglutination was positive on two occasions when the reference method found normal levels. No false negative reactions occurred. Bacterial micro-organisms were isolated on 32 occasions but 19 of the organisms were considered to represent bacterial colonisation or contamination. The CRP remained negative in 17 cases. There were 13 episodes of clinical deterioration associated with positive bacterial cultures. In each of the six infants with severe systemic infections (septicaemia (4), meningitis (1), and osteomyelitis (1)), the levels were raised. In five of these infants the CRP was elevated before, or at the time of, the clinical deterioration. The CRP remained normal during seven (54%) of the culture positive events. We believe that the CRP estimations provide additional information in the evaluation of the infant with suspected sepsis. Serial measurements are helpful in distinguishing bacterial contamination from invasive infection but are not helpful in predicting infection during the pre-clinical phase. The intralipid agglutination technique is a rapid and reliable test and could be performed on the neonatal unit outside normal laboratory hours.

journal_name

J Perinat Med

authors

Shortland DB,MacFadyen U,Elston A,Harrison G

doi

10.1515/jpme.1990.18.3.157

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

157-63

issue

3

eissn

0300-5577

issn

1619-3997

journal_volume

18

pub_type

杂志文章
  • A novel method for evaluating uterine cervical consistency using vaginal ultrasound gray-level histogram.

    abstract:AIMS:To evaluate uterine cervical consistency using a vaginal ultrasound gray-level histogram. METHODS:Vaginal ultrasound and digital examination were performed for 214 women with low-risk singleton pregnancy during 27-30(th) pregnancy week. The mean gray-level (MGL) of an ultrasound gray-level histogram, representing...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm.2010.079

    authors: Kuwata T,Matsubara S,Taniguchi N,Ohkuchi A,Ohkusa T,Suzuki M

    更新日期:2010-09-01 00:00:00

  • Systematic pH-measurements in the umbilical artery: causes and predictive value of neonatal acidosis.

    abstract::Subpartal and neonatal blood gas analyses have attracted increasing interest during the past 20 years. Different studies have been carried out to investigate the causes and immediate consequences of perinatal acidosis. It was the aim of this study to examine the long term outcome of acidotic-born babies. During 16 con...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1983.11.6.278

    authors: Lauener PA,Calame A,Janecek P,Bossart H,Monod JF

    更新日期:1983-01-01 00:00:00

  • Changes in lymphocyte subsets during pregnancy and post-partum in cases of beginning eclampsia.

    abstract:AIMS:The goal of the present retrospective study was to examine the peripheral blood lymphocytes for expression of phenotypic and activation markers concerning the development of hypertension in pregnancy. METHODS:16 women (aged 25-43 years; mean 35.1) developing hypertension in the third trimester (week 25-34) have h...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2000.050

    authors: Kühnert M,Schmidt S

    更新日期:2000-01-01 00:00:00

  • Alternatives to the antenatal glucocorticoid treatment for the prevention of respiratory distress syndrome.

    abstract::Various substances and methods are used as alternatives to corticoids for stimulating antenatal pulmonary maturation. This study discusses thyroid hormones, intralipid, ambroxol, carnitine, theophylline (aminophylline) and betasympathomimetic agents. ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1987.15.5.453

    authors: Dudenhausen JW

    更新日期:1987-01-01 00:00:00

  • Continuous fetal pH monitoring and neonatal Apgar score.

    abstract::Results of continuous fetal tissue pH monitoring were compared to neonatal APGAR scores one minute after delivery in 81 successful tissue pH recordings. The sensitivity of the method (i.e. the ability of the method to find the low APGAR neonates) was 67 per cent using an APGAR score limit between 8 and 9 and a pH limi...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1980.8.3.158

    authors: Weber T

    更新日期:1980-01-01 00:00:00

  • Comparison of image quality in brain MRI with and without MR compatible incubator and predictive value of brain MRI at expected delivery date in preterm babies.

    abstract::Objectives MR compatible incubators (MRcI) offer the examination of preterm and critically ill infants in controlled environment. The aim of the study was to compare objective and subjective image quality as well as diagnostic value of MRI brain examinations with and without using the MRcI. Thus, predictive value of b...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2020-0051

    authors: Müller F,Proquitté H,Herrmann KH,Lehmann T,Mentzel HJ

    更新日期:2020-09-25 00:00:00

  • Optimization of human milk fortification for preterm infants: new concepts and recommendations.

    abstract::Preterm infants fed fortified human milk (HM) in standard (STD) fashion grow slower than preterm formula fed infants. Recently, low protein intake has been proven to be the primary limiting factor responsible for this growth failure. The main reason of protein undernutrition despite fortification is that STD fortifica...

    journal_title:Journal of perinatal medicine

    pub_type: 指南,杂志文章

    doi:10.1515/jpm.2010.073

    authors: Arslanoglu S,Moro GE,Ziegler EE,The Wapm Working Group On Nutrition

    更新日期:2010-05-01 00:00:00

  • Randomized trial of administration of prostaglandin E2 gel for induction of labor in the morning or the evening.

    abstract:OBJECTIVE:To compare the outcome of induction of labor and patient's preferences using a protocol with the first dose of prostaglandin E2 endocervical gel in the evening versus a protocol with the first dose in the morning. DESIGN:We performed a randomized trial comparing administration of prostaglandin E2 endocervica...

    journal_title:Journal of perinatal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1515/JPM.2000.003

    authors: Oei SG,Jongmans L,Mol BW

    更新日期:2000-01-01 00:00:00

  • Myocardial infarction in early pregnancy.

    abstract::Acute myocardial infarction (AMI) during pregnancy is usually transmural and occurs in late pregnancy with a peak incidence during the peripartum or postpartum periods. We report a pregnancy-related AMI, which occurring as early as the first trimester, was treated conservatively with antithrombotic and anti-ischemic d...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2004.127

    authors: Stefanovic V,Ulander VM,Graner M,Kupari M,Kaaja R

    更新日期:2004-01-01 00:00:00

  • Maturation of the autonomic nervous system: differences in heart rate variability in premature vs. term infants.

    abstract:AIMS:Heart rate variability (HRV) reveals information on the functional state of the autonomic nervous system (ANS). This study was initiated to assess the physiological- and maturational development of the ANS by comparing HRV data of healthy prematures with term infants. METHODS:Short-term recordings of HRV in 39 pr...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2006.058

    authors: Longin E,Gerstner T,Schaible T,Lenz T,König S

    更新日期:2006-01-01 00:00:00

  • Observations on the energy and redox state and protein synthetic rate in animal and human placentas.

    abstract::The energy and redox states of placentas in newly anesthetized or sacrificed guinea pigs and sheep were compared with that of human placentas immediately after delivery. Subsequently the effect of ischemia was observed in both human and animal placentas. The influence of perfusion, using a fluid containing oxygenated ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1987.15.1.21

    authors: Carroll MJ,Young M

    更新日期:1987-01-01 00:00:00

  • Assessing the utility of the Healthy Start Screen to predict an elevated Edinburgh Postnatal Depression Scale score.

    abstract::Objective To examine the utility of the Healthy Start Screen (HSS), which is an assessment of health, environment, and behavioral risk factors offered to all pregnant women in the state of Florida, in identifying women at risk for developing postpartum depression (PPD). Methods The sample for this Institutional Review...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2019-0472

    authors: Padilla MM,Roussos-Ross D,Goodin AJ

    更新日期:2020-06-25 00:00:00

  • No difference between home and clinic blood pressure measurements in pregnancy: a computerized telemetric study.

    abstract::Many decisions in pregnancy are based on one or two casual blood pressure estimations made in the antenatal clinic. No previous study has challenged the validity of this practice or attempted to discover whether there are significant differences between the blood pressures of pregnant women when they are measured in t...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1991.19.1-2.133

    authors: Mooney P,Jaspar A,Cartwright W,Swindells HE,Dalton KJ

    更新日期:1991-01-01 00:00:00

  • Amikacin alters auditory brainstem conduction time in newborns.

    abstract::The purpose of this paper was to describe whether there are some relationships between amikacin serum levels and central conduction time in brainstem auditory evoked potentials (BAEP) within therapeutic range levels in newborns as index of drug toxicity in brainstem auditory centers in neonatally exposed infants. We p...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2003.032

    authors: Poblano A,Belmont A,Sosa J,Ibarra J,Vargas AM,Limón G,Martínez C

    更新日期:2003-01-01 00:00:00

  • Fenoterol depot and fenoterol in premature uterine contractions--a multicentric double-blind comparative study.

    abstract::In a double-blind randomized study, the effect of a single dose of a fenoterol preparation with delayed release of active substance (designated as fenoterol depot) was compared with a fenoterol product with undelayed release of active substance (designated as fenoterol) in two groups respectively comprising 66 and 65 ...

    journal_title:Journal of perinatal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1515/jpme.1987.15.1.95

    authors: Müller-Holve W,Hermer M,Klöck FK,Kreis M,Brehm H,Elser H,Kitschke HJ,Berg D,Harms V,Hägele D

    更新日期:1987-01-01 00:00:00

  • Evidence of the escape of antithrombin from the blood into the interstitial space in pregnant women.

    abstract:OBJECTIVE:we investigated whether ascites samples obtained from pregnant women during cesarean sections contained antithrombin because it is unknown whether antithrombin escapes from the blood and passes into the interstitial space during pregnancy. METHODS:the concentration and activity levels of antithrombin were de...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm.2010.106

    authors: Morikawa M,Yamada T,Yamada T,Koyama T,Akaishi R,Takeda M,Araki N,Cho K,Minakami H

    更新日期:2010-11-01 00:00:00

  • MR imaging of the fetal brain at 1.5T and 3.0T field strengths: comparing specific absorption rate (SAR) and image quality.

    abstract:OBJECTIVES:Our two objectives were to evaluate the feasibility of fetal brain magnetic resonance imaging (MRI) using a fast spin echo sequence at 3.0T field strength with low radio frequency (rf) energy deposition (as measured by specific absorption rate: SAR) and to compare image quality, tissue contrast and conspicui...

    journal_title:Journal of perinatal medicine

    pub_type: 临床试验,杂志文章

    doi:10.1515/jpm-2014-0268

    authors: Krishnamurthy U,Neelavalli J,Mody S,Yeo L,Jella PK,Saleem S,Korzeniewski SJ,Cabrera MD,Ehterami S,Bahado-Singh RO,Katkuri Y,Haacke EM,Hernandez-Andrade E,Hassan SS,Romero R

    更新日期:2015-03-01 00:00:00

  • MTHFR C677T polymorphism, folate, vitamin B12 and homocysteine in recurrent pregnancy losses: a case control study among North Indian women.

    abstract:AIM:The present study attempts to understand the role of methylenetetrahydrofolate reductase C677T (MTHFR C677T) in recurrent pregnancy losses in North Indian women because of hyperhomocysteinemia in light of serum folate and vitamin B₁₂. METHODS:One hundred and seven women with three or more consecutive unexplained r...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2012-0252

    authors: Puri M,Kaur L,Walia GK,Mukhopadhhyay R,Sachdeva MP,Trivedi SS,Ghosh PK,Saraswathy KN

    更新日期:2013-09-01 00:00:00

  • Waterbirth: water temperature and bathing time--mother knows best!

    abstract:OBJECTIVES:The Frauenfeld Clinic for Obstetrics and Gynecology introduced waterbirths in 1991. This work examines whether guidelines for water temperature and bathing are actually necessary. METHODS:This 8-year prospective clinical study follows 10,775 births in a regional women's hospital (non-selected population). N...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2002.058

    authors: Geissbuehler V,Eberhard J,Lebrecht A

    更新日期:2002-01-01 00:00:00

  • Skeletal muscular changes in Pena-Shokeir sequence.

    abstract::Histologic examination of the skeletal muscles in 8 fetuses and newborn patients with the Pena-Shokeir sequence revealed only minor nonspecific changes which could not be ascribed to any of the well defined myopathies. Muscle fiber diameters were increased in 2 out of 5 patients examined. No significant malformations ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1990.18.4.267

    authors: Reiser P,Briner J,Schinzel A

    更新日期:1990-01-01 00:00:00

  • Which information will be given to parents of preterm infants--a comparison of estimates and local data.

    abstract:OBJECTIVE:Parents of preterm infants require information on morbidity and duration of common interventions performed in the NICU. Since locally achieved data are often not available, information is mainly based on educated guesses of health care professionals. The present study compares estimates of neonatal nurses or ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1515/JPM.2007.074

    authors: Rüdiger M,Iffländer S,Reichert J,Bätzel C,Reiter G,Wauer RR

    更新日期:2007-01-01 00:00:00

  • Serum calcium and 25-OH-D3 in mothers of newborns with craniotabes.

    abstract::Serum calcium and 25-OH-D3 in mothers of newborns with craniotabes. The aim of this study was to investigate whether calcium or vitamin D balance during late pregnancy have influence on the outcome of newborn craniotabes. 27 mothers and their fullterm newborns with craniotabes in two series were studied for clinical f...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1983.11.2.127

    authors: Kokkonen J,Koivisto M,Lautala P,Kirkinen P

    更新日期:1983-01-01 00:00:00

  • Discordant anencephaly with a cleft lip and palate in a pergonal-induced triplet pregnancy.

    abstract::Anencephaly in triplets and pergonal induced pregnancies is a very rare incident. Associated cleft lip and palate has never been reported in these case. In this paper we report the first case of an anencephalic infant with cleft lip and palate in a set of pergonal-induced discordant triplet pregnancy. ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1992.20.3.241

    authors: Rejjal AR,Abu-Osba YK

    更新日期:1992-01-01 00:00:00

  • Determination of fetal maturity and of development of the fetal lungs by means of combined methods.

    abstract::The validity of the assessment of the fetal age and pulmonary maturity was evaluated on 369 patients at various stages of normal pregnancy and complicated by diabetes, toxemia and fetal anencephaly. Gestational maturity was assessed by ultrasonic measurement of the fetal biparietal diameter and by analysing constituen...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1975.3.2.105

    authors: Ianniruberto A,Destro F,Capozzi A,Zisa F,Cubesi G,Parisi S

    更新日期:1975-01-01 00:00:00

  • Follow-up studies of newborn-babies with congenital ventriculomegaly.

    abstract:UNLABELLED:The authors present the results of their follow-up studies of data from the last four years on patients with congenital ventriculomegaly. OBJECTIVE:To study the psychomotor and mental developmental outcome of neonates with congenital ventriculomegaly diagnosed prenatally. In addition, patients were also cla...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.1999.067

    authors: Beke A,Csabay L,Rigó J Jr,Harmath A,Papp Z

    更新日期:1999-01-01 00:00:00

  • Inferior vena cava diameter pulse waveforms in the human fetus: relationship with flow velocity waveform.

    abstract::Our purpose was to evaluate the hemodynamic significance of fetal inferior vena cava (IVC) flow velocity waveform indices during fetal development in relation to the diameter pulse waveform. Doppler ultrasound and a phase locked loop echo tracking system were used to measure flow velocity waveform and diameter pulse w...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2006.082

    authors: Mori A,Uchida N,Inomo A,Izumi S,Ichikawa I

    更新日期:2006-01-01 00:00:00

  • Justified skepticism about Apgar scoring in out-of-hospital birth settings.

    abstract:BACKGROUND:The Apgar score is used worldwide to assess the newborn infant shortly after birth. Apgar scores, including mean scores and those with high cut-off scores, have been used to support claims that planned home birth is as safe as hospital birth. The purpose of this study was to determine the distribution of 5 m...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2014-0003

    authors: Grünebaum A,McCullough LB,Brent RL,Arabin B,Levene MI,Chervenak FA

    更新日期:2015-07-01 00:00:00

  • The concentration of bupivacaine in fetal organs during obstetrical epidural analgesia.

    abstract::The concentration of bupivacaine in organs of non-viable human fetuses after obstetrical epidural analgesia in customary doses was investigated. The concentrations were determined with a gas chromatograph. The material consisted of a fetus who died following termination in the 24th week of pregnancy three minutes afte...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1986.14.4.219

    authors: Müller-Holve W,von Meyer L,Nagler P

    更新日期:1986-01-01 00:00:00

  • Perinatal mortality in the Federation of Bosnia and Herzegovina.

    abstract:AIM:The aim of the study was to investigate the most frequent causes of perinatal mortality in Bosnia and Herzegovina. METHODS:We analyzed in a retrospective study over a one year period (1999) the following cantons: Sarajevo, Mostar, Tuzla, Bihać, Gorazde, Travnik, Zenica, which represent about one half of the popula...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2001.035

    authors: Fatusić Z

    更新日期:2001-01-01 00:00:00

  • Fetal and uteroplacental flow velocity waveforms in abruptio placentae: report of two cases.

    abstract::This paper reports two cases of abruptio placentae assessed using pulsed Doppler at 29 and 30 weeks of gestation. Transvaginal pulsed Doppler showed abnormal uterine artery FVWs in both cases. One fetus with normal umbilical and normal middle cerebral artery FVWs was not acidotic and only midly hypoxic, whereas the ot...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1994.22.5.441

    authors: Sekizuka N,Hanaoka J,Takeuchi Y,Tokunaga A

    更新日期:1994-01-01 00:00:00