Abstract:
AIM:To compare oxidative stress in patients with preeclampsia (PE) or intrauterine growth restriction (IUGR) vs. normal pregnancy (controls) during 48 h after delivery. STUDY DESIGN:Women with singleton pregnancies were recruited immediately after delivery (gestational age >26.0 weeks). Women with PE or IUGR were matched with healthy controls by age, BMI, gestational age and delivery mode. Venous blood samples and urine samples were tested for oxidative stress products 24 h and 48 h after delivery. RESULTS:Plasma malondialdehyde (MDA) concentration 24 h after delivery was significantly higher in subjects with PE or IUGR (3.41+/-1.14 micromol/L, n=20) than in controls (2.91+/-0.82 micromol/L, n=38) (P=0.04). Urine iPF(2alpha)-VI declined from 24 to 48 h after delivery significantly in controls (P=0.006) and not in subjects with PE or IUGR (P=0.71). CONCLUSION:Of the markers tested only MDA is indicating higher oxidative stress in women with PE/IUGR than in normal pregnancy and only at 24 h after delivery. No consistent pattern of change in the oxidative stress markers exists between 24-48 h after delivery.
journal_name
J Perinat Medjournal_title
Journal of perinatal medicineauthors
Kressig P,Beinder E,Schweer H,Zimmermann R,von Mandach Udoi
10.1515/JPM.2008.053subject
Has Abstractpub_date
2008-01-01 00:00:00pages
310-5issue
4eissn
0300-5577issn
1619-3997pii
10.1515/JPM.2008.053journal_volume
36pub_type
杂志文章abstract::Background Little is known about the impact of peptic ulcer disease (PUD) on pregnancy. Our objective was to evaluate the effect of PUD on pregnancy and newborn outcomes. Methods A retrospective cohort study was carried out using the Healthcare Cost and Utilization Project (HCUP)-National Inpatient Sample (NIS) from t...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2019-0344
更新日期:2020-03-26 00:00:00
abstract:AIM:To discover the potential role of recombinant VEGF121 (rVEGF121) injection for the prevention of fetal growth restriction in a preeclampsia (PE) mouse model (Mus musculus). SUBJECTS AND METHODS:This is an experimental study of 30 pregnant mice that were randomly divided into three groups: normal, PE, and PE with r...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2016-0149
更新日期:2017-02-01 00:00:00
abstract::Subpartal and neonatal blood gas analyses have attracted increasing interest during the past 20 years. Different studies have been carried out to investigate the causes and immediate consequences of perinatal acidosis. It was the aim of this study to examine the long term outcome of acidotic-born babies. During 16 con...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1983.11.6.278
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Influenza presents with increased morbidity and mortality in children ≤5 months of age. Vaccination of caregivers is indicated, but immunization rates are estimated at only 30%. The 2009 New York State Neonatal Influenza Protection Act (NIPA) mandated offering of influenza vaccine to caregivers during the po...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0248
更新日期:2014-11-01 00:00:00
abstract:AIMS:To evaluate uterine cervical consistency using a vaginal ultrasound gray-level histogram. METHODS:Vaginal ultrasound and digital examination were performed for 214 women with low-risk singleton pregnancy during 27-30(th) pregnancy week. The mean gray-level (MGL) of an ultrasound gray-level histogram, representing...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.079
更新日期:2010-09-01 00:00:00
abstract::The value of testing for inherited thrombophilia in pregnancy has been debated in literature with regard to its utility in preventing adverse obstetrical outcomes or identifying women at risk for it. In this commentary, an evidence based approach is used to investigate the strength of association between thrombophilia...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0075
更新日期:2015-03-01 00:00:00
abstract::To determine if oxytocin dosage used for labor induction differed in obese and lean women, we analyzed records of patients who underwent term labor induction and delivered vaginally. Each of a cohort of 27 patients with a body mass index (BMI) >40 kg/m2 was matched with a patient with a BMI <28 kg/m2 for gestational a...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0134
更新日期:2015-11-01 00:00:00
abstract:UNLABELLED:The authors present the results of their follow-up studies of data from the last four years on patients with congenital ventriculomegaly. OBJECTIVE:To study the psychomotor and mental developmental outcome of neonates with congenital ventriculomegaly diagnosed prenatally. In addition, patients were also cla...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.1999.067
更新日期:1999-01-01 00:00:00
abstract:AIM:The current therapeutic strategies to reduce macrosomia rates in gestational diabetes (GDM) have focused on the normalizing of maternal glucose levels. The aim of our study was 1.) to compare maternal glycemic values with the presence of fetal macrosomia at different gestational ages (GA) and with LGA at birth in a...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2002.046
更新日期:2002-01-01 00:00:00
abstract:AIM:The present study attempts to understand the role of methylenetetrahydrofolate reductase C677T (MTHFR C677T) in recurrent pregnancy losses in North Indian women because of hyperhomocysteinemia in light of serum folate and vitamin B₁₂. METHODS:One hundred and seven women with three or more consecutive unexplained r...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2012-0252
更新日期:2013-09-01 00:00:00
abstract::Single dose pharmacokinetics of 75 mg aspirin was investigated in two groups of ten women with clinically normal pregnancies. Eleven non-pregnant subjects in the same age were controls. In group A, gestational age was 27-30 completed weeks, and in group B, 36-39 weeks. Venous blood samples were taken before and up to ...
journal_title:Journal of perinatal medicine
pub_type: 临床试验,杂志文章
doi:10.1515/jpme.1994.22.3.205
更新日期:1994-01-01 00:00:00
abstract::The development of assisted reproduction techniques (ART) represents an important advance in the treatment of human infertility. However, their great effectiveness has brought with it an excessive increase in multiple pregnancy rates with the serious medical, financial and social consequences that they entail. Now, th...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm.2011.020
更新日期:2011-05-01 00:00:00
abstract:AIM:The aim of this study was to assess the risk of subsequent delivery complications after extremely preterm deliveries by initial (index) pregnancy mode of delivery (MOD): cesarean (CD) versus vaginal (VD). METHODS:This is a retrospective, longitudinal cohort study using Washington State birth certificate data and I...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2013-0023
更新日期:2013-11-01 00:00:00
abstract::To determine the optimal time of delivery, in terms of lowest risk of peripartum complications, the relative incidences of the parameters. Abnormal cardiotocogram (CTG), operative vaginal delivery, Apgar < 7 at 1 and 5 min, artery cord blood pH < 7.20, blood loss > 500 ml, epidural anesthesia, and Cesarean section, we...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1996.24.6.661
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Gestational weight gain (GWG) above the recently recommended ranges is likely to be related to adverse pregnancy outcomes and therefore a challenge in industrialized countries. AIMS:We conducted a systematic review on observational studies in order to gain more evidence on whether diets with lower caloric/p...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm.2010.127
更新日期:2011-03-01 00:00:00
abstract::Universally 4 million newborns die and another 4 million are stillborn every year. 98% of these neonatal deaths take place in the developing countries. Looking at the state of the world's newborns one can see that neonatal mortality rate is about 4-5 per 1000 in the developed countries and nearly 10 fold this in the d...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2003.060
更新日期:2003-01-01 00:00:00
abstract::Our aim was to evaluate the literature on survival and major disability rate in preterm infants born at 22- 25 weeks of gestational age (GA). Thirty-three studies were identified and reviewed. Survival was lower in population-based studies (2% at 22, 13% at 23, 35% at 24, and 56% at 25 weeks) than in center-based stud...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2009.117
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:Pregravid maternal weight and appropriate weight gain during pregnancy might be associated with increased cesarean section rate. STUDY DESIGN:We used data from the Slovenian National Perinatal Information System to select singleton pregnancies born at ≥38 weeks, during the period between 2003 and 2012. We ca...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0117
更新日期:2016-05-01 00:00:00
abstract::The introduction of maternal serological screening for chromosome disorders in pregnancy in women aged over 30 years at the estimated date of delivery was monitored in two hospitals. The test used involved measurement of three substances in maternal serum combined with maternal age (the triple test). This is the first...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1991.19.3.151
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To evaluate whether uterotrophic agents increase the risk of fatal hemorrhagic brain stroke. METHODS:Between 1991 and 1992, there were 230 maternal deaths among 2,420,000 pregnant women in Japan and the causes of these deaths was investigated in 1994. Using information provided in this report, we identified ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.116
更新日期:2011-01-01 00:00:00
abstract::We reviewed the literature on the use of inhaled nitric oxide and the influence of supplemental oxygen on bronchopulmonary dysplasia (BPD), and the role of endogenous nitric oxide-synthase, vascular endothelial growth factor, the interplay of nitric oxide and superoxide, protein nitration and the nuclear factor kappa ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2008.065
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To compare normal ranges of ultrasonographically measured fetal nasal bone length in the second trimester between different ethnic groups. METHOD:A prospective, non-interventional study in order to establish normal ranges of fetal nasal bone length in the second trimester in a Greek population was conducted ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0296
更新日期:2016-03-01 00:00:00
abstract::Background Monocytes, after neutrophils, are the most abundant white blood cells found in the amniotic cavity of women with intra-amniotic inflammation/infection. However, the origin of such cells has not been fully investigated. Herein, we determined (1) the origin of amniotic fluid monocytes/macrophages from women w...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2019-0262
更新日期:2019-10-25 00:00:00
abstract:BACKGROUND:A known side effect of labour epidural analgesia (EDA) is maternal fever. It is unclear whether this has effects on the anti-infectious management of the neonate. METHODS:A systematic literature search and a hand search of abstract publications were conducted. Studies reporting sepsis evaluation or antibiot...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,meta分析
doi:10.1515/jpm-2012-0064
更新日期:2012-11-01 00:00:00
abstract::We report on an exceptional therapy with epidural anesthesia and tunnelling of the peridural catheter over a time period of 2-14 days in patients with threatening early preterm labor, intact membranes and vaginal engagement of the infants (4 singleton, 8 twin and 2 triplet pregnancies). A combination of bupivacaine (0...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2008.081
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To examine the population-based trend for cesarean births in twin pregnancies for the last 13 years in Slovenia, and to find correlates for this trend. METHODS:We evaluated data from the Slovenian national perinatal information system (NPIS) of all twin pairs born at ≥24 weeks during the period 1997-2009 (n=...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2011.129
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:The transcatheter pelvic arterial embolization (TAE) is effective for postpartum hemorrhage (PPH). There has been a little information about the factors for ineffectiveness of TAE. The aim of this study was to determine factors associated with TAE failure for PPH. STUDY DESIGN:Fifty-five women who underwent ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2013-0242
更新日期:2014-05-01 00:00:00
abstract::Objective To evaluate fetal behavioral differences between singleton and twin fetuses before 20 weeks of gestation using four-dimensional (4D) ultrasound. Methods 4D ultrasound was used to examine fetal movements in 58 singleton and 48 twin normal fetuses at 12-19 weeks. The frequencies of eight fetal movements were a...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2017-0158
更新日期:2018-10-25 00:00:00
abstract::The transcutaneous PO2 (tcPO2) response to blood interruption (BIS test) was measured in 6 healthy adults and 28 infants, including premature infants. The response was similar in both infants and adults with a time lag at the beginning of blood interruption, a subsequent linear decrease, a time lag at the end of blood...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1992.20.5.371
更新日期:1992-01-01 00:00:00
abstract::In preterm infants, feeding with human milk (HM) is a very effective intervention for the prevention of infections and necrotizing enterocolitis (NEC), and for potentially improved neurocognitive and cardiovascular outcomes in the long-term. Hospitals and physicians are advised to recommend HM for preterm and other hi...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,实务指引
doi:10.1515/jpm.2010.064
更新日期:2010-07-01 00:00:00