Genome-Wide Identification and Expression Analysis of the Ascorbate Oxidase Gene Family in Gossypium hirsutum Reveals the Critical Role of GhAO1A in Delaying Dark-Induced Leaf Senescence.

Abstract:

:Ascorbate oxidase (AO) plays important roles in plant growth and development. Previously, we reported a cotton AO gene that acts as a positive factor in cell growth. Investigations on Gossypium hirsutum AO (GhAO) family genes and their multiple functions are limited. The present study identified eight GhAO family genes and performed bioinformatic analyses. Expression analyses of the tissue specificity and developmental feature of GhAOs displayed their diverse expression patterns. Interestingly, GhAO1A demonstrated the most rapid significant increase in expression after 1 h of light recovery from the dark. Additionally, the transgenic ao1-1/GhAO1AArabidopsis lines overexpressing GhAO1A in the Arabidopsisao1-1 late-flowering mutant displayed a recovery to the normal phenotype of wild-type plants. Moreover, compared to the ao1-1 mutant, the ao1-1/GhAO1A transgenic Arabidopsis presented delayed leaf senescence that was induced by the dark, indicating increased sensitivity to hydrogen peroxide (H2O2) under normal conditions that might be caused by a reduction in ascorbic acid (AsA) and ascorbic acid/dehydroascorbate (AsA/DHA) ratio. The results suggested that GhAOs are functionally diverse in plant development and play a critical role in light responsiveness. Our study serves as a foundation for understanding the AO gene family in cotton and elucidating the regulatory mechanism of GhAO1A in delaying dark-induced leaf senescence.

journal_name

Int J Mol Sci

authors

Pan Z,Chen L,Wang F,Song W,Cao A,Xie S,Chen X,Jin X,Li H

doi

10.3390/ijms20246167

subject

Has Abstract

pub_date

2019-12-06 00:00:00

issue

24

issn

1422-0067

pii

ijms20246167

journal_volume

20

pub_type

杂志文章
  • Comparative microRNA-seq Analysis Depicts Candidate miRNAs Involved in Skin Color Differentiation in Red Tilapia.

    abstract::Differentiation and variation in body color has been a growing limitation to the commercial value of red tilapia. Limited microRNA (miRNA) information is available on skin color differentiation and variation in fish so far. In this study, a high-throughput Illumina sequencing of sRNAs was conducted on three color vari...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19041209

    authors: Wang L,Zhu W,Dong Z,Song F,Dong J,Fu J

    更新日期:2018-04-16 00:00:00

  • Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients.

    abstract::We previously reported that AR phosphorylation at serine 213 was associated with poor outcome and may contribute to prostate cancer development and progression. This study investigates if specific AR phosphorylation sites have differing roles in the progression of hormone naïve prostate cancer (HNPC) to castrate resis...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms140816656

    authors: McCall P,Adams CE,Willder JM,Bennett L,Qayyum T,Orange C,Underwood MA,Edwards J

    更新日期:2013-08-13 00:00:00

  • A Census and Categorization Method of Epitranscriptomic Marks.

    abstract::In the past few years, thorough investigation of chemical modifications operated in the cells on ribonucleic acid (RNA) molecules is gaining momentum. This new field of research has been dubbed "epitranscriptomics", in analogy to best-known epigenomics, to stress the potential of ensembles of RNA modifications to cons...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21134684

    authors: Mathlin J,Le Pera L,Colombo T

    更新日期:2020-06-30 00:00:00

  • Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study.

    abstract::Extracellular matrix protein turnover may play an important role in left atrial (LA) remodelling. The aim is to investigate the associations between matrix metalloproteinase (MMPs), tissue inhibitor of metalloproteinase (TIMP-1) and LA volume index (LAVI) and if these associations are independent of TIMP-1 levels. Par...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21144944

    authors: Linssen PBC,Brunner-La Rocca HP,Schalkwijk CG,Beulens JWJ,Elders PJM,van der Heijden AA,Slieker RC,Stehouwer CDA,Henry RMA

    更新日期:2020-07-13 00:00:00

  • Construction of a Lectin-Glycan Interaction Network from Enterohemorrhagic Escherichia coli Strains by Multi-omics Analysis.

    abstract::Enterohemorrhagic Escherichia coli (EHEC) causes hemorrhagic colitis and hemolytic uremic syndrome. EHEC infection begins with bacterial adherence to the host intestine via lectin-like adhesins that bind to the intestinal wall. However, EHEC-related lectin-glycan interactions (LGIs) remain unknown. Here, we conducted ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21082681

    authors: Cho SH,Lee KM,Kim CH,Kim SS

    更新日期:2020-04-12 00:00:00

  • Natural Bioactive Compounds: The Way Shown by Professor Maurizio Battino and His Group in an Italian Cutting-Edge Laboratory.

    abstract::Maurizio Battino, Ph.D., Associate Professor of Biochemistry in the Department of Clinical Sciences, Faculty of Medicine, Università Politecnica delle Marche (Italy), is the Director of the Centre for Health and Nutrition, Universidad Europea del Atlantico (Santander, Spain) and Director of Nutrition and Health projec...

    journal_title:International journal of molecular sciences

    pub_type: 面试

    doi:10.3390/ijms17071038

    authors: Editorial Office International Journal Of Molecular Sciences.

    更新日期:2016-07-05 00:00:00

  • Environmental dependence of artifact CD peaks of chiral Schiff base 3d-4f complexes in soft mater PMMA matrix.

    abstract::Four chiral Schiff base binuclear 3d-4f complexes (NdNi, NdCu, GdNi, and GdCu) have been prepared and characterized by means of electronic and CD spectra, IR spectra, magnetic measurements, and X-ray crystallography (NdNi). A so-called artifact peak of solid state CD spectra, which was characteristic of oriented molec...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms12106966

    authors: Okamoto Y,Nidaira K,Akitsu T

    更新日期:2011-01-01 00:00:00

  • Integrated Proteomics and Metabolomics Analysis Provides Insights into Ganoderic Acid Biosynthesis in Response to Methyl Jasmonate in Ganoderma Lucidum.

    abstract::Ganoderma lucidum is widely recognized as a medicinal basidiomycete. It was previously reported that the plant hormone methyl jasmonate (MeJA) could induce the biosynthesis of ganoderic acids (GAs), which are the main active ingredients of G. lucidum. However, the regulatory mechanism is still unclear. In this study, ...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20246116

    authors: Jiang AL,Liu YN,Liu R,Ren A,Ma HY,Shu LB,Shi L,Zhu J,Zhao MW

    更新日期:2019-12-04 00:00:00

  • The Rice Alpha-Amylase, Conserved Regulator of Seed Maturation and Germination.

    abstract::Alpha-amylase, the major form of amylase with secondary carbohydrate binding sites, is a crucial enzyme throughout the growth period and life cycle of angiosperm. In rice, alpha-amylase isozymes are critical for the formation of the storage starch granule during seed maturation and motivate the stored starch to nouris...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms20020450

    authors: Damaris RN,Lin Z,Yang P,He D

    更新日期:2019-01-21 00:00:00

  • A Pilot Study of the Predictive Potential of Chemosensitivity and Gene Expression Assays Using Circulating Tumour Cells from Patients with Recurrent Ovarian Cancer.

    abstract::Circulating tumour cells (CTCs) from liquid biopsies are under current investigation in several cancers, including epithelial ovarian cancer (EOC) but face significant drawbacks in terms of non-standardised methodology, low viable cell numbers and accuracy of CTC identification. In this pilot study, we report that che...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21134813

    authors: Guadagni S,Clementi M,Masedu F,Fiorentini G,Sarti D,Deraco M,Kusamura S,Papasotiriou I,Apostolou P,Aigner KR,Zavattieri G,Farina AR,Vizzielli G,Scambia G,Mackay AR

    更新日期:2020-07-07 00:00:00

  • Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA.

    abstract::Endonuclease IV (EndoIV) is a DNA damage-specific endonuclease that mainly hydrolyzes the phosphodiester bond located at 5' of an apurinic/apyrimidinic (AP) site in DNA. EndoIV also possesses 3'-exonuclease activity for removing 3'-blocking groups and normal nucleotides. Here, we report that Thermococcus eurythermalis...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20010069

    authors: Wang WW,Zhou H,Xie JJ,Yi GS,He JH,Wang FP,Xiao X,Liu XP

    更新日期:2018-12-24 00:00:00

  • Genetic Identification and Transcriptome Analysis of Lintless and Fuzzless Traits in Gossypium arboreum L.

    abstract::Cotton fibres, as single cells arising from the seed coat, can be classified as lint and fuzz according to their final length. Gossypium arboreum is a cultivated diploid cotton species and a potential donor of the A subgenome of the more widely grown tetraploid cottons. In this study, we performed genetic studies on o...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21051675

    authors: Liu X,Moncuquet P,Zhu QH,Stiller W,Zhang Z,Wilson I

    更新日期:2020-02-29 00:00:00

  • Synthesis of a Cleaved Form of Osteopontin by THP-1 Cells and Its Alteration by Phorbol 12-Myristate 13-Acetate and BCG Infection.

    abstract::The protease-cleaved osteopontin (OPN) was proposed to enhance the migration of memory T cells to granulomas in tuberculosis. Various forms of OPN were identified in human monocytic THP-1 cells stimulated by phorbol 12-myristate 13-acetate (PMA). Antibodies O-17, 10A16 and 34E3, which recognize N-terminus, the C-half,...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19020418

    authors: Bai G,Motoda H,Ozuru R,Chagan-Yasutan H,Hattori T,Matsuba T

    更新日期:2018-01-31 00:00:00

  • The Transcriptomic Landscape of Gastric Cancer: Insights into Epstein-Barr Virus Infected and Microsatellite Unstable Tumors.

    abstract:BACKGROUND:Epstein-Barr Virus (EBV) positive and microsatellite unstable (MSI-high) gastric cancer (GC) are molecular subgroups with distinctive molecular profiles. We explored the transcriptomic differences between EBV+ and MSI-high GCs, and the expression of current GC immunotherapy targets such as PD-1, PD-L1, CTLA4...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19072079

    authors: Gullo I,Carvalho J,Martins D,Lemos D,Monteiro AR,Ferreira M,Das K,Tan P,Oliveira C,Carneiro F,Oliveira P

    更新日期:2018-07-17 00:00:00

  • CYP3A5 Genotype as a Potential Pharmacodynamic Biomarker for Tacrolimus Therapy in Ulcerative Colitis in Japanese Patients.

    abstract::Tacrolimus has been used to induce remission in patients with steroid-refractory ulcerative colitis. It poses a problem of large individual differences in dosage necessary to attain target blood concentration and, often, this leads to drug inefficacy. We examined the difference in mRNA expression levels of ATP binding...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21124347

    authors: Yamamoto Y,Nakase H,Matsuura M,Maruyama S,Masuda S

    更新日期:2020-06-18 00:00:00

  • Effect of Lead (Pb) on Inflammatory Processes in the Brain.

    abstract::That the nervous system is the main target of lead (Pb) has long been considered an established fact until recent evidence has linked the Pb effect on the immune system to the toxic effects of Pb on the nervous system. In this paper, we present recent literature reports on the effect of Pb on the inflammatory processe...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms17122140

    authors: Chibowska K,Baranowska-Bosiacka I,Falkowska A,Gutowska I,Goschorska M,Chlubek D

    更新日期:2016-12-19 00:00:00

  • Redox Signaling and Regional Heterogeneity of Endothelial Dysfunction in db/db Mice.

    abstract::The variable nature of vascular dysfunction in diabetes is not well understood. We explored the functional adaptation of different arteries in db/db mice in relation to increased severity and duration of diabetes. We compared endothelium-dependent and -independent vasodilation in the aortae, as well as the carotid and...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21176147

    authors: Sallam NA,Laher I

    更新日期:2020-08-26 00:00:00

  • Targeting Molecular Mechanisms Underlying Treatment Efficacy and Resistance in Osteosarcoma: A Review of Current and Future Strategies.

    abstract::Osteosarcoma is the most common primary malignant bone tumour in children and adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure. Introduction of combination chemotherapy in the 1970s, however, dramatically increased overall survival rates from 20% to approximately 70%. Unfortunat...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms21186885

    authors: Lilienthal I,Herold N

    更新日期:2020-09-19 00:00:00

  • Collateral Vessels Have Unique Endothelial and Smooth Muscle Cell Phenotypes.

    abstract::Collaterals are unique blood vessels present in the microcirculation of most tissues that, by cross-connecting a small fraction of the outer branches of adjacent arterial trees, provide alternate routes of perfusion. However, collaterals are especially susceptible to rarefaction caused by aging, other vascular risk fa...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20153608

    authors: Zhang H,Chalothorn D,Faber JE

    更新日期:2019-07-24 00:00:00

  • Administration of Zinc plus Cyclo-(His-Pro) Increases Hippocampal Neurogenesis in Rats during the Early Phase of Streptozotocin-Induced Diabetes.

    abstract::The effects of zinc supplementation on hippocampal neurogenesis in diabetes mellitus have not been studied. Herein, we investigated the effects of zinc plus cyclo-(His-Pro) (ZC) on neurogenesis occurring in the subgranular zone of dentate gyrus after streptozotocin (STZ)-induced diabetes. ZC (27 mg/kg) was administere...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms18010073

    authors: Choi BY,Kim IY,Kim JH,Lee BE,Lee SH,Kho AR,Sohn M,Suh SW

    更新日期:2017-01-01 00:00:00

  • Nonenzymatic Spontaneous Oxidative Transformation of 5,6-Dihydroxyindole.

    abstract::Melanin is an important phenolic skin pigment found throughout the animal kingdom. Tyrosine and its hydroxylated product dopa provide the starting material for melanin biosynthesis in all animals. Through a set of well-established reactions, they are converted to 5,6-dihydroxyindole (DHI) and DHI-2-carboxylic acid (DH...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21197321

    authors: Sugumaran M,Evans J,Ito S,Wakamatsu K

    更新日期:2020-10-03 00:00:00

  • Roles of Dkk2 in the Linkage from Muscle to Bone during Mechanical Unloading in Mice.

    abstract::Mechanical unloading simultaneously induces muscle and bone loss, but its mechanisms are not fully understood. The interactions between skeletal muscle and bone have been recently noted. Although canonical wingless-related integration site (Wnt)/β-catenin signaling is crucial for bone metabolism, its roles in the musc...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21072547

    authors: Kawao N,Morita H,Iemura S,Ishida M,Kaji H

    更新日期:2020-04-06 00:00:00

  • Distinct Carbon and Nitrogen Metabolism of Two Contrasting Poplar Species in Response to Different N Supply Levels.

    abstract::Poplars have evolved various strategies to optimize acclimation responses to environmental conditions. However, how poplars balance growth and nitrogen deficiency remains to be elucidated. In the present study, changes in root development, carbon and nitrogen physiology, and the transcript abundance of associated gene...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19082302

    authors: Meng S,Wang S,Quan J,Su W,Lian C,Wang D,Xia X,Yin W

    更新日期:2018-08-06 00:00:00

  • Ultrastructural and Photosynthetic Responses of Pod Walls in Alfalfa to Drought Stress.

    abstract::Increasing photosynthetic ability as a whole is essential for acquiring higher crop yields. Nonleaf green organs (NLGOs) make important contributions to photosynthate formation, especially under stress conditions. However, there is little information on the pod wall in legume forage related to seed development and yie...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21124457

    authors: Wang H,Zhou Q,Mao P

    更新日期:2020-06-23 00:00:00

  • Biodegradation of Bisphenol A by Sphingobium sp. YC-JY1 and the Essential Role of Cytochrome P450 Monooxygenase.

    abstract::Bisphenol A (BPA) is a widespread pollutant threatening the ecosystem and human health. An effective BPA degrader YC-JY1 was isolated and identified as Sphingobium sp. The optimal temperature and pH for the degradation of BPA by strain YC-JY1 were 30 °C and 6.5, respectively. The biodegradation pathway was proposed ba...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21103588

    authors: Jia Y,Eltoukhy A,Wang J,Li X,Hlaing TS,Aung MM,Nwe MT,Lamraoui I,Yan Y

    更新日期:2020-05-19 00:00:00

  • Cell Type-Specific TGF-β Mediated EMT in 3D and 2D Models and Its Reversal by TGF-β Receptor Kinase Inhibitor in Ovarian Cancer Cell Lines.

    abstract::Transcriptome profiling of 3D models compared to 2D models in various cancer cell lines shows differential expression of TGF-β-mediated and cell adhesion pathways. Presence of TGF-β in these cell lines shows an increased invasion potential which is specific to cell type. In the present study, we identified exogenous a...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms20143568

    authors: Al Ameri W,Ahmed I,Al-Dasim FM,Ali Mohamoud Y,Al-Azwani IK,Malek JA,Karedath T

    更新日期:2019-07-22 00:00:00

  • The Antipsychotic D2AAK1 as a Memory Enhancer for Treatment of Mental and Neurodegenerative Diseases.

    abstract::The treatment of memory impairments associated with the central nervous system diseases remains an unmet medical need with social and economic implications. Here we show, that a multi-target ligand of aminergic G protein-coupled receptors with antipsychotic activity in vivo (D2AAK1) stimulates neuron growth and surviv...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms21228849

    authors: Koszła O,Sołek P,Woźniak S,Kędzierska E,Wróbel TM,Kondej M,Archała A,Stępnicki P,Biała G,Matosiuk D,Kaczor AA

    更新日期:2020-11-23 00:00:00

  • Update on the Impact of Omega 3 Fatty Acids on Inflammation, Insulin Resistance and Sarcopenia: A Review.

    abstract::Elderly and patients affected by chronic diseases face a high risk of muscle loss and impaired physical function. Omega 3 fatty acids (FA) attenuate inflammation and age-associated muscle loss, prevent systemic insulin resistance and improve plasma lipids, potentially impacting on sarcopenia. This paper aims to review...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章,评审

    doi:10.3390/ijms19010218

    authors: Buoite Stella A,Gortan Cappellari G,Barazzoni R,Zanetti M

    更新日期:2018-01-11 00:00:00

  • Baicalin Inhibits Haemophilus Parasuis-Induced High-Mobility Group Box 1 Release during Inflammation.

    abstract::Haemophilus parasuis (H. parasuis) can cause Glässer’s disease in pigs. However, the molecular mechanism of the inflammation response induced by H. parasuis remains unclear. The high-mobility group box 1 (HMGB1) protein is related to the pathogenesis of various infectious pathogens, but little is known abou...

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms19051307

    authors: Fu S,Liu H,Chen X,Qiu Y,Ye C,Liu Y,Wu Z,Guo L,Hou Y,Hu CA

    更新日期:2018-04-27 00:00:00

  • Effects of Titanium Mesh Surfaces-Coated with Hydroxyapatite/β-Tricalcium Phosphate Nanotubes on Acetabular Bone Defects in Rabbits.

    abstract::The management of severe acetabular bone defects in revision reconstructive orthopedic surgery is challenging. In this study, cyclic precalcification (CP) treatment was used on both nanotube-surface Ti-mesh and a bone graft substitute for the acetabular defect model, and its effects were assessed in vitro and in vivo....

    journal_title:International journal of molecular sciences

    pub_type: 杂志文章

    doi:10.3390/ijms18071462

    authors: Nguyen TT,Bae TS,Yang DH,Park MS,Yoon SJ

    更新日期:2017-07-07 00:00:00