Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ihara T,Nakamura Y,Mitsui T,Tsuchiya S,Kanda M,Kira S,Nakagomi H,Sawada N,Kamiyama M,Shigetomi E,Shinozaki Y,Yoshiyama M,Nakao A,Koizumi S,Takeda Mdoi
10.1038/s41598-019-53132-2subject
Has Abstractpub_date
2019-11-08 00:00:00pages
16731issue
1issn
2045-2322pii
10.1038/s41598-019-53132-2journal_volume
9pub_type
已发布勘误abstract::Cutaneous allodynia (CA) is a pain in response to non-nociceptive stimulation and a marker of central sensitisation. Probable migraine (PM) is a migraine subtype that fulfils all but one criterion of migraine. Headache intensity and the disability of individuals with PM are similar or lower than individuals with migra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82080-z
更新日期:2021-01-28 00:00:00
abstract::In this work, we address the ubiquitous phenomenon of Fano resonances in bilayer graphene. We consider that this phenomenon is as exotic as other phenomena in graphene because it can arise without an external extended states source or elaborate nano designs. However, there are not theoretical and/or experimental studi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16838-9
更新日期:2017-12-01 00:00:00
abstract::During the infection process, the influenza fusion peptide (FP) inserts into the host membrane, playing a crucial role in the fusion process between the viral and host membranes. In this work we used a combination of simulation and experimental techniques to analyse the molecular details of this process, which are lar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28099
更新日期:2016-06-15 00:00:00
abstract::Parasites alter many traits of their hosts. In particular, parasites known as "manipulative" may increase their probability of transmission by inducing phenotypic alterations in their intermediate hosts. Although parasitic-induced alterations can modify species' ecological roles, the proximate factors modulating this ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68577-z
更新日期:2020-07-15 00:00:00
abstract::Mammalian parental genomes contribute differently to early embryonic development. Before activation of the zygotic genome, the maternal genome provides all transcripts and proteins required for the transition from a highly specialized oocyte to a pluripotent embryo. Depletion of these maternally-encoded transcripts fr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44667
更新日期:2017-03-20 00:00:00
abstract::This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the inhibition of HMG-CoA reductase and of non-steroidal isoprenoid intermediates, exert extra-beneficial effect in preventing atherosclerosis beyond their effect on the...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35119-7
更新日期:2018-11-12 00:00:00
abstract::The epidermal growth factor receptor (EGFR) inhibitors such as erlotinib and gefitinib are widely used for treatment of non-small cell lung cancer (NSCLC), but they have shown limited efficacy in an unselected population of patients. The KRAS mutations, which are identified in approximately 20% of NSCLC patients, have...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37059-8
更新日期:2019-01-24 00:00:00
abstract::Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction. We recently developed an innovative experimental model of indivi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21205
更新日期:2016-02-15 00:00:00
abstract::We have assembled the complete sequence of the Durio zibethinus chloroplast genome using long PacBio reads. Durian is a valuable commercial tree that produces durian fruit, which is popular in Southeast Asia. The chloroplast genome assembled into a single 143 kb cyclic contig that contained 111 genes. There were 46 sh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73549-4
更新日期:2020-10-07 00:00:00
abstract::We aimed to assess whether brain volumes may affect the results of deep brain stimulation (DBS) in patients with Parkinson's disease (PD). Eighty-one consecutive patients with PD (male:female 40:41), treated with DBS between June 2012 and December 2017, were enrolled. Total and regional brain volumes were measured usi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79138-9
更新日期:2020-12-16 00:00:00
abstract::Acoustic telemetry is one of the primary technologies for studying the behavior and survival of fishes throughout the world. The size and performance of the transmitter are key limiting factors. The newly developed injectable transmitter is the first acoustic transmitter that can be implanted via injection instead of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42999
更新日期:2017-02-21 00:00:00
abstract::Sesame is prized for its oil. Genetic improvement of sesame can be enhanced through marker-assisted breeding. However, few simple sequence repeat (SSR) markers and SSR-based genetic maps were available in sesame. In this study, 7,357 SSR markers were developed from the sesame genome and transcriptomes, and a genetic m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08858-2
更新日期:2017-08-21 00:00:00
abstract::Metabolic syndrome (MS) could be associated with liver function. Our study aimed to investigate the association between liver function and MS in a large cohort of Chinese men and women. We enrolled 32,768 ostensibly healthy participants. The associations between liver function and MS of both genders were analyzed sepa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44844
更新日期:2017-03-20 00:00:00
abstract::Major alterations in metabolism occur during pregnancy enabling the mother to provide adequate nutrients to support infant development, affecting birth weight (BW) and potentially long-term risk of obesity and cardiometabolic disease. We classified dynamic changes in the maternal lipidome during pregnancy and identifi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71081-z
更新日期:2020-08-26 00:00:00
abstract::The Andaman day gecko (Phelsuma andamanensis) is endemic to the Andaman Archipelago, located ~ 6000 km away from Madagascar where the genus Phelsuma likely evolved. We complemented existing phylogenetic data with additional markers to show that this species consistently branches off early in the evolution of the genus...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68402-7
更新日期:2020-07-16 00:00:00
abstract::Recently, sex steroid membrane receptors garnered world-wide attention because they may be related to sex hormone-mediated unknown rapid non-genomic action that cannot be currently explained by their genomic action via nuclear receptors. Progesterone affects cell proliferation and survival via non-genomic effects. In ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05423-9
更新日期:2017-07-12 00:00:00
abstract::This study used resting-state functional MRI (r-fMRI) to evaluate intrinsic brain activity in drug-naive patients with essential tremor (ET) with and without head tremor. We enrolled 20 patients with ET with hand and head tremor (h-ET), 27 patients with ET without head tremor (a-ET), and 27 healthy controls (HCs). All...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28778-z
更新日期:2018-07-12 00:00:00
abstract::Patients with chronic obstructive pulmonary disease (COPD) repeat acute exacerbations (AE). Global Initiative for Chronic Obstructive Lung Disease (GOLD) is only available for patients in stable phase. Currently, there is a lack of assessment and prediction methods for acute exacerbation of chronic obstructive pulmona...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60042-1
更新日期:2020-02-20 00:00:00
abstract::Hepadnaviruses, including human hepatitis B virus (HBV), replicate their tiny DNA genomes by protein-primed reverse transcription of a pregenomic (pg) RNA. Replication initiation as well as pgRNA encapsidation depend on the interaction of the viral polymerase, P protein, with the ε RNA element, featuring a lower and a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07657-z
更新日期:2017-08-02 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-39693-2
更新日期:2019-04-17 00:00:00
abstract::Sleep has been hypothesised to maintain a close relationship with metabolism. Here we focus on the brain structure that triggers slow-wave sleep, the ventrolateral preoptic nucleus (VLPO), to explore the cellular and molecular signalling pathways recruited by an increase in glucose concentration. We used infrared vide...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19107
更新日期:2016-01-12 00:00:00
abstract::Arbuscular mycorrhizal fungi (AMF) and phosphate solubilizing bacteria (PSB) could interact synergistically because PSB solubilize sparingly available phosphorous compounds into orthophosphate that AMF can absorb and transport to the host plant. Little is known about the interactions between these two groups in terms ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61846-x
更新日期:2020-03-18 00:00:00
abstract::The purpose was to evaluate intra and inter-rater reliability, repeatability and absolute accuracy between ultrasound imaging (US) and caliper measures to determine Spring ligament (SL) dimensions in cadavers. SLs were identified from 62 human feet from formaldehyde-embalmed cadavers. Intra and inter-observer reliabil...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51384-6
更新日期:2019-10-15 00:00:00
abstract::Single nucleotide polymorphisms (SNPs) and genes associated with susceptibility to hepatitis B virus (HBV) infection that have been identified by genome-wide association studies explain only a limited portion of the known heritability, indicating more genetic variants remain to be discovered. In this study, we adopted...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49777-8
更新日期:2019-09-17 00:00:00
abstract::This study investigated the glucono-δ-lactone (GDL)-induced aggregation of isoflavones and soy proteins in soymilk. High-performance liquid chromatography (HPLC) analysis indicated that isoflavones mixed with β-conglycinin (7S) and glycinin (11S) proteins formed 7S-isoflavone and 11S-isoflavone complexes in soymilk su...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35718
更新日期:2016-10-20 00:00:00
abstract::Transition metal cobalt (Co) nanoparticle was designed as catalyst to promote the conversion reaction of Sn to SnO2 during the delithiation process which is deemed as an irreversible reaction. The designed nanocomposite, named as SnO2/Co3O4/reduced-graphene-oxide (rGO), was synthesized by a simple two-step method comp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09164
更新日期:2015-03-17 00:00:00
abstract::Fibrolamellar carcinoma (FLC) is a unique liver cancer primarily affecting young adults and characterized by a fusion event between DNAJB1 and PRKACA. By analyzing RNA-sequencing data from The Cancer Genome Atlas (TCGA) for >9,100 tumors across ~30 cancer types, we show that the DNAJB1-PRKACA fusion is specific to FLC...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44653
更新日期:2017-03-17 00:00:00
abstract::Rheumatoid Arthritis (RA) is a chronic inflammatory disorder where incidence and severity of myocardial infarction are increased. Data on the incidence and outcome of stroke are conflicting. Thus, we investigated outcome after Ischemia/Reperfusion (I/R) brain injury in a mouse model of RA and assessed for the role of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38670-z
更新日期:2019-02-18 00:00:00
abstract::During the search for a potent antifungal drug, a cell-permeable metabolite was isolated from a soil isolate taxonomically identified as Penicillium radicum. The strain was found to be a potent antifungal agent. Production conditions of the active compound were optimized and the active compound was isolated, purified,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11948
更新日期:2015-07-10 00:00:00
abstract::The recombination is one of the most frequently identified drivers of double-stranded DNA viruses evolution. However, the recombination events in African swine fever virus (ASFV) genomes have been poorly annotated. We hypothesize that the genetic determinants of ASFV variability are potential hot-spots for recombinati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75377-y
更新日期:2020-10-28 00:00:00