Abstract：
PURPOSE:Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) provides reasonable performance in detecting significant cancers. Still, it is unclear about whether all PI-RADS 4 lesions show the same cancer detection rate (CDR) regardless of tumor size. The aim was to compare the CDRs of small (< 10 mm) and large (≥ 10 mm) PI-RADS 4. METHODS:After magnetic resonance imaging (MRI) was performed in 684 men, a radiologist interpreted the MR images and detected 281 index lesions categorized as PI-RADS 4 in 281 men. PI-RADS 4 lesions were divided into small and large groups on size of 10 mm. Overall and significant CDRs were compared between the groups. A significant cancer was defined as one with Gleason score (GS) ≥ 7 or tumor volume ≥ 0.5 ml. Tumor volumes were roughly calculated as πr34/3 (π = 3.14 and r = a half of tumor size) and were compared between the groups. Standard reference was a biopsy examination. Fisher's exact and Mann-Whitney tests were used for statistical analysis. RESULTS:The overall CDRs of small and large groups were 39.0% (53/136) and 59.3% (86/145), respectively, (p = 0.0008). The median tumor volumes of cancer-proven small and large groups were 0.18 ml (0.01-0.38 ml) and 0.70 ml (0.52-1.44 ml), respectively (p < 0.0001). Using GS or tumor volume, the significant CDRs of these groups were 26.5% (36/136) and 59.3% (86/145), respectively (p < 0.0001), and using GS alone, 26.5% (36/136) and 39.3% (57/145), respectively (p = 0.0232). CONCLUSIONS:PI-RADS 4 lesions should be sub-divided on size of 10 mm because of different significant CDRs.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Park SY,Park BKdoi
10.1007/s00345-019-02924-2subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1473-1479issue
6eissn
0724-4983issn
1433-8726pii
10.1007/s00345-019-02924-2journal_volume
38pub_type
杂志文章abstract：PURPOSE:The use of a ureteral access sheath (UAS) during flexible retrograde intrarenal surgery (RIRS) has become increasingly popular. Our aim was to evaluate the accessibility of a new UAS device, allowing the transformation of the working guidewire into a safety guidewire. METHODS:A prospective, multicenter study w...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-013-1094-3
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:To assess the feasibility, safety, and outcomes of an expedited One-Stop prostate cancer (PCa) diagnostic pathway. PATIENTS AND METHODS:We identified 370 consecutive patients who underwent multiparametric magnetic resonance imaging (mpMRI) and transrectal ultrasound fusion prostate biopsy (MRI/TRUS-PBx) from o...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02835-2
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:Salvage radiotherapy (SRT) for biochemical recurrence (BCR) following radical prostatectomy (RP) should if possible be added at a prostate-specific antigen (PSA) level of <1-2 ng/mL. The value of positron emission tomography combined with computed tomography (PET/CT) at such low PSA values is not defined. The p...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1547-y
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:This study evaluated the baseline patient characteristics associated with the time to biochemical progression and overall survival in patients who participated in a phase II trial on zoledronic acid combined with the initial androgen-deprivation therapy for treatment-naïve bone-metastatic prostate cancer. METH...
journal_title：World journal of urology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00345-014-1431-1
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:To critically review and synthesize data of ureteroscopy (URS) in different circumstances that all urologists may encounter during everyday clinical practice, such as pregnancy, obesity, bleeding diathesis, renal stones larger than 2 cm, calyceal diverticula, and kidney malformations. METHODS:According to PRIS...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-014-1345-y
更新日期：2015-02-01 00:00:00
abstract：:Growth and morphogenesis of the prostate involves mesenchymal-epithelial interactions. Transforming growth factor-beta 1 (TGF-beta1) is one growth factor that may play a role in these paracrine interactions. We have localized TGF-beta1 by molecular and immunohistochemical analysis in the developing mouse prostate. Acc...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00191212
更新日期：1995-01-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2135-0
更新日期：2018-03-01 00:00:00
abstract：:Non-gonococcal urethritis (NGU) is conventionally treated with oral antibiotics. With this Phase II study, we investigated the action of a locally disinfecting substance, Instillagel, in symptomatic NGU. Instillation treatment was performed twice daily to 32 male patients with symptomatic NGU. To evaluate the therapeu...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
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更新日期：2002-05-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
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更新日期：2019-04-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s003450100218
更新日期：2001-08-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00184602
更新日期：1996-01-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/PL00007071
更新日期：2000-02-01 00:00:00
abstract：:The most important phosphates involved in urinary stone disease are carbonate apatite, brushite, and struvite. Overall, phosphate stones account for 12-20% of all stones, with a downward trend for struvite and an increase in carbonate apatite being observed in the last decade. The physicochemical basis for the formati...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050152
更新日期：1999-10-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-019-02792-w
更新日期：2020-02-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2079-4
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:To investigate pathological and oncological outcomes of obese patients who underwent robot-assisted radical prostatectomy (RARP) compared with laparoscopic radical prostatectomy (LRP) or open retropubic radical prostatectomy (RRP) since limited comparative data exist with regard to oncological and survival o...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1326-1
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:To examine phosphodiesterase type 5 (PDE5) expression in the anterior fibromuscular stroma (AFMS) of the prostate. Although PDE5 expression was identified in the human prostate, differences in PDE5 expression in intra-prostatic regions are unknown. The AFMS in the prostate has peculiar innervations that could c...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03095-1
更新日期：2020-11-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03161-8
更新日期：2020-03-21 00:00:00
abstract：:Successful management of transitional-cell carcinoma of the urinary bladder is greatly dependent upon regular surveillance and early detection of persistent or recurrent carcinoma. The development of a highly sensitive urinary test for the detection of transitional-cell carcinoma of the bladder could have a dramatic i...
journal_title：World journal of urology
pub_type： 杂志文章,评审
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更新日期：1997-01-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1280-y
更新日期：2015-01-01 00:00:00
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journal_title：World journal of urology
pub_type： 临床试验,杂志文章
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更新日期：2004-06-01 00:00:00
abstract：:Contemporary literature regarding the management of neobladder-vaginal fistula and stress urinary incontinence following radical cystectomy and neobladder reconstruction in women is reviewed in this article. Neobladder-vaginal fistula is uncommon but mandates meticulous repair. Compared to the native bladder, the wall...
journal_title：World journal of urology
pub_type： 杂志文章,评审
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更新日期：2005-09-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-011-0800-2
更新日期：2013-08-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-013-1099-y
更新日期：2014-06-01 00:00:00
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journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/BF00182052
更新日期：1994-01-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02867-8
更新日期：2020-12-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-004-0458-0
更新日期：2004-12-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0235-6
更新日期：2008-04-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02858-9
更新日期：2020-07-01 00:00:00
abstract：:Tissue engineering, long a matter of myth and dream throughout the history of medicine, is now a practical reality. A wide spectrum of biological materials are used in the field of urology to treat disease and to overcome human disabilities, including tissue grafts and organ transplantation. Laboratory-engineered biop...
journal_title：World journal of urology
pub_type： 历史文章,杂志文章
doi：10.1007/s003450050015
更新日期：2000-02-01 00:00:00
