Abstract：
:Multiple parasitic arthropods of medical importance depend on symbiotic bacteria. While the link between scabies and secondary bacterial infections causing post infective complications of Group A streptococcal and staphylococcal pyoderma is increasingly recognized, very little is known about the microbiota of Sarcoptes scabiei. Here we analyze adult female mite and egg metagenome datasets. The majority of adult mite bacterial reads matched with Enterobacteriaceae (phylum Proteobacteria), followed by Corynebacteriaceae (phylum Actinobacteria). Klebsiella was the most dominant genus (78%) and Corynebacterium constituted 9% of the assigned sequences. Scabies mite eggs had a more diverse microbial composition with sequences from Proteobacteria being the most dominant (75%), while Actinobacteria, Bacteroidetes and Firmicutes accounted for 23% of the egg microbiome sequences. DNA sequences of a potential endosymbiont, namely Streptomyces, were identified in the metagenome sequence data of both life stages. The presence of Streptomyces was confirmed by conventional PCR. Digital droplet PCR indicated higher Streptomyces numbers in adult mites compared to eggs. Streptomyces were localized histologically in the scabies mite gut and faecal pellets by Fluorescent In Situ Hybridization (FISH). Streptomyces may have essential symbiotic roles in the scabies parasite intestinal system requiring further investigation.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Swe PM,Zakrzewski M,Waddell R,Sriprakash KS,Fischer Kdoi
10.1038/s41598-019-47892-0subject
Has Abstractpub_date
2019-08-13 00:00:00pages
11744issue
1issn
2045-2322pii
10.1038/s41598-019-47892-0journal_volume
9pub_type
杂志文章abstract：:Since the production of ferromagnetic graphene as an extremely important matter in spintronics has made a revolution in future technology, a great deal of efforts has recently been done to reach a simple and cost-effective method. Up to now, controlling the magnetic properties at extremely low temperature have been in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78262-w
更新日期：2020-12-07 00:00:00
abstract：:This study investigated the glucono-δ-lactone (GDL)-induced aggregation of isoflavones and soy proteins in soymilk. High-performance liquid chromatography (HPLC) analysis indicated that isoflavones mixed with β-conglycinin (7S) and glycinin (11S) proteins formed 7S-isoflavone and 11S-isoflavone complexes in soymilk su...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35718
更新日期：2016-10-20 00:00:00
abstract：:Zeolites/molecular sieves with uniform, molecular-sized pores are important for many adsorption-based separation processes. Pore size gaps, however, exist in the current zeolite family. This leads to a great challenge of separating molecules with size differences at ~0.01 nm level. Here, we report a novel concept, por...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13981
更新日期：2015-09-11 00:00:00
abstract：:Understanding of avian nocturnal flight comes mainly from northern hemisphere species in seasonal temperate ecosystems where nocturnal flight is often precisely timed and entrained by annual photoperiod. Here we investigate patterns of nocturnal flight in waterbirds of Australian desert ecosystems that fly considerabl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17859-0
更新日期：2017-12-14 00:00:00
abstract：:Cancer patients often use dietary supplements while on therapy, but little is known about interactions of supplements with cancer chemotherapy. Black raspberries (BRB) have anti-cancer effects, but have not been evaluated for interference with chemotherapy for castrate-resistant prostate cancer (CRPC). Here we studied...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39589-1
更新日期：2019-03-13 00:00:00
abstract：:Activation of short-chain free fatty acid receptors 3 (FFAR3) has been suggested to promote sympathetic outflow in postganglionic sympathetic neurons or hamper it by a negative coupling to N-type calcium (CaV2.2) channels. Heterogeneity of FFAR3 expression in sympathetic neurons, however, renders single neurons studie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35690-z
更新日期：2018-11-26 00:00:00
abstract：:Incorporation of Zn atoms into a nanosize Cu lattice is known to alter the electronic properties of Cu, improving catalytic performance in a number of industrially important reactions. However the structural influence of Zn on the Cu phase is not well studied. Here, we show that Cu nano-clusters modified with increasi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20527
更新日期：2016-02-09 00:00:00
abstract：:In bacteria, selective promoter recognition by RNA polymerase is achieved by its association with σ factors, accessory subunits able to direct RNA polymerase "core enzyme" (E) to different promoter sequences. Using Chromatin Immunoprecipitation-sequencing (ChIP-seq), we searched for promoters bound by the σ(S)-associa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10469
更新日期：2015-05-28 00:00:00
abstract：:This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the inhibition of HMG-CoA reductase and of non-steroidal isoprenoid intermediates, exert extra-beneficial effect in preventing atherosclerosis beyond their effect on the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35119-7
更新日期：2018-11-12 00:00:00
abstract：:In using nanostructures to design solar thermal absorbers, computational methods, such as rigorous coupled-wave analysis and the finite-difference time-domain method, are often employed to simulate light-structure interactions in the solar spectrum. However, those methods require heavy computational resources and CPU ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51407-2
更新日期：2019-10-21 00:00:00
abstract：:Carotenoids are anti-oxidative agents. Human skin and eyes contain specific carotenoid species known to prevent various pathologies caused by oxidative stress. We quantified skin and eye carotenoid levels and investigated their potential correlation in a population including 985 Japanese patients and staff members of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45751-6
更新日期：2019-06-27 00:00:00
abstract：:Research on argillite as a possible host rock for nuclear waste disposal is still an open subject since many issues need to be clarified. In the Underground Research Laboratories constructed for this purpose, a damaged zone around the excavation has been systematically observed and characterized by the appearance of m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08815
更新日期：2015-03-06 00:00:00
abstract：:In inflammatory bowel disease (IBD), compromised restitution of the epithelial barrier contributes to disease severity. Owing to the complexity in the pathogenesis of IBD, a variety of factors have been implicated in its progress. In this study, we report a functional interaction between macroautophagy and Corticotrop...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23342
更新日期：2016-03-18 00:00:00
abstract：:Despite the fact that 2015 was the international year of light, no mention was made of the fact that radiation contains entropy as well as energy, with different spectral distributions. Whereas the energy function has been vastly studied, the radiation entropy distribution has not been analysed at the same speed. The ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01622-6
更新日期：2017-05-10 00:00:00
abstract：:Migraines are a common and undertreated disease and often have psychiatric comorbidities; however, the abnormal mechanism of emotional processing in migraine patients has not been well clarified. This study sought to investigate the different brain functional activation to neutral, positive and negative emotional stim...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41919
更新日期：2017-02-09 00:00:00
abstract：:The structures, stabilities, and electronic properties of monolayer black phosphorus (M-BP) with different kinds of defects are investigated within the frame of density-functional theory. All the possible configurations of defects in M-BP are explored, and the calculated results suggest that the stabilities of the con...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10848
更新日期：2015-06-02 00:00:00
abstract：:The precise manner in which physical changes to the breast cancer susceptibility protein (BRCA1) affect its role in DNA repair events remain unclear. Indeed, cancer cells harboring mutations in BRCA1 suffer from genomic instability and increased DNA lesions. Here, we used a combination of molecular imaging and biochem...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43435
更新日期：2017-03-06 00:00:00
abstract：:Micronutrients are essential for survival and growth for all the organisms including pathogens. In this manuscript, we report that zinc (Zn) chelator N,N,N',N'-tetrakis(2-pyridinylmethyl)-1,2-ethylenediamine (TPEN) affects growth and viability of intracellular pathogen Leishmania donovani (LD) by a concentration and t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10041-6
更新日期：2017-09-05 00:00:00
abstract：:Mammalian motor cortex consists of several interconnected subregions thought to play distinct roles in voluntary movements, yet their specific role in decision making and execution is not completely elucidated. Here we used transient optogenetic inactivation of the caudal forelimb area (CFA) and rostral forelimb area ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15835-2
更新日期：2017-11-17 00:00:00
abstract：:Ocular graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation (HSCT). Here we compared the diagnostic rates of ocular GVHD, including its severity, prognosis and the agreement, obtained using three grading scales: the National Institutes of Health (NIH) eye score, Japan...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06680
更新日期：2014-10-22 00:00:00
abstract：:Urinary biomarkers augment the diagnosis of acute kidney injury (AKI), with AKI after cardiovascular surgeries being a prototype of prognosis scenario. Glutathione S-transferases (GST) were evaluated as biomarkers of AKI. Urine samples were collected in 141 cardiovascular surgical patients and analyzed for urinary alp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26335
更新日期：2016-08-16 00:00:00
abstract：:The purpose of this study was to analyze spatiotemporal parameters of gait in children using varyingly loaded Backpacks(BP). This cross-sectional study examined 231 schoolchildren (118 boys, 113 girls) aged six to 12 years, carrying a traditional BP to manipulate loading (Crossing Backpack Children Arpenaz 7 Litres, J...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48675-3
更新日期：2019-08-21 00:00:00
abstract：:A new family of 99mTc(I)- tricarbonyl complexes and 125I-heteroaromatic compounds bearing an acridine orange (AO) DNA targeting unit was evaluated for Auger therapy. Characterization of the DNA interaction, performed with the non-radioactive Re and 127I congeners, confirmed that all compounds act as DNA intercalators....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42544
更新日期：2017-02-13 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-62065-0
更新日期：2020-04-22 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-77251-3
更新日期：2020-11-18 00:00:00
abstract：:There is a demand for ultra low-loss metal films with high-quality single crystals and perfect surface for nanophotonics and quantum information processing. Many researches are devoted to alternative materials, but silver is by far theoretically the most preferred low-loss material at optical and near-IR frequencies. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48508-3
更新日期：2019-08-22 00:00:00
abstract：:Infrared detection devices are becoming miniature with micro or nano-scale size. The advantages of downsizing come on the expense of insufficient collection of infrared radiation. Therefore, utilizing nano-plasmonic optical antennas becomes mandatory. However, it is desirable to develop antennas with broad bandwidth, ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48648-6
更新日期：2019-08-21 00:00:00
abstract：:Recent advances in genetic analyses have significantly refined human type 1 diabetes (T1D) associated loci. The goal of such effort is to identify the causal genes and have a complete understanding of the molecular pathways that independently or interactively influence cellular processes leading to the destruction of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68956-6
更新日期：2020-07-21 00:00:00
abstract：:Maternal overnutrition increases the risk of long-term metabolic dysfunction in offspring. Exercise improves metabolism partly by upregulating mitochondrial biogenesis or function, via increased levels of nicotinamide adenine dinucleotide (NAD+). We have shown that the NAD+ precursor, nicotinamide mononucleotide (NMN)...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14866-z
更新日期：2017-11-08 00:00:00
abstract：:Expression of the mismatch repair gene MutL homolog 1 (MLH1) is silenced in a clinically important subgroup of sporadic colorectal cancers. These cancers exhibit hypermutability with microsatellite instability (MSI) and differ from microsatellite-stable (MSS) colorectal cancers in both prognosis and response to therap...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-019-49952-x
更新日期：2019-09-17 00:00:00
