Abstract：
:Compelling evidence supports a tight link between oxidative stress and protein aggregation processes, which are noticeably involved in the development of proteinopathies, such as Alzheimer's disease, Parkinson's disease, and prion disease. The literature is tremendously rich in studies that establish a functional link between both processes, revealing that oxidative stress can be either causative, or consecutive, to protein aggregation. Because oxidative stress monitoring is highly challenging and may often lead to artefactual results, cutting-edge technical tools have been developed recently in the redox field, improving the ability to measure oxidative perturbations in biological systems. This review aims at providing an update of the previously known functional links between oxidative stress and protein aggregation, thereby revisiting the long-established relationship between both processes.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Lévy E,El Banna N,Baïlle D,Heneman-Masurel A,Truchet S,Rezaei H,Huang ME,Béringue V,Martin D,Vernis Ldoi
10.3390/ijms20163896subject
Has Abstractpub_date
2019-08-09 00:00:00issue
16issn
1422-0067pii
ijms20163896journal_volume
20pub_type
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