Three-dimensional character of the deformation twin in magnesium.

abstract：:Perceptual decisions are accompanied by feelings of confidence that reflect the likelihood that the decision was correct. Here we aim to clarify the relationship between perception and confidence by studying the same perceptual task across three different confidence contexts. Human observers were asked to categorize t...

journal_title：Nature communications

authors： Balsdon T,Wyart V,Mamassian P

更新日期：2020-04-09 00:00:00

abstract：:Deregulation of mitochondrial network in terminally differentiated cells contributes to a broad spectrum of disorders. Methylmalonic acidemia (MMA) is one of the most common inherited metabolic disorders, due to deficiency of the mitochondrial methylmalonyl-coenzyme A mutase (MMUT). How MMUT deficiency triggers cell d...

journal_title：Nature communications

authors： Luciani A,Schumann A,Berquez M,Chen Z,Nieri D,Failli M,Debaix H,Festa BP,Tokonami N,Raimondi A,Cremonesi A,Carrella D,Forny P,Kölker S,Diomedi Camassei F,Diaz F,Moraes CT,Di Bernardo D,Baumgartner MR,Devuyst O

更新日期：2020-02-20 00:00:00

abstract：:An egg must be fertilized by a single sperm only. To prevent polyspermy, the zona pellucida, a structure that surrounds mammalian eggs, becomes impermeable upon fertilization, preventing the entry of further sperm. The structural changes in the zona upon fertilization are driven by the exocytosis of cortical granules....

journal_title：Nature communications

authors： Cheeseman LP,Boulanger J,Bond LM,Schuh M

更新日期：2016-12-19 00:00:00

abstract：:Standard optical tweezers rely on optical forces arising when a focused laser beam interacts with a microscopic particle: scattering forces, pushing the particle along the beam direction, and gradient forces, attracting it towards the high-intensity focal spot. Importantly, the incoming laser beam is not affected by t...

journal_title：Nature communications

authors： Kalantarifard F,Elahi P,Makey G,Maragò OM,Ilday FÖ,Volpe G

更新日期：2019-06-18 00:00:00

abstract：:Fas induces apoptosis in activated T cell to maintain immune homeostasis, but the effects of non-apoptotic Fas signaling on T cells remain unclear. Here we show that Fas promotes TH9 cell differentiation by activating NF-κB via Ca2+-dependent PKC-β activation. In addition, PKC-β also phosphorylates p38 to inactivate N...

journal_title：Nature communications

authors： Shen Y,Song Z,Lu X,Ma Z,Lu C,Zhang B,Chen Y,Duan M,Apetoh L,Li X,Guo J,Miao Y,Zhang G,Yang D,Cai Z,Wang J

更新日期：2019-07-02 00:00:00

abstract：:Previous transcriptomic profiling studies have typically focused on separately analyzing mRNA expression, alternative splicing and alternative polyadenylation differences between cell and tissue types. However, the relative contribution of these three transcriptomic regulatory layers to cell type specification is poor...

journal_title：Nature communications

authors： Ha KCH,Sterne-Weiler T,Morris Q,Weatheritt RJ,Blencowe BJ

更新日期：2021-01-12 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders. We synthesized a diffusible photochromic glutamate analogue, azobenzene-triazole-glutamate (ATG), which is specific for NMDARs and functions as a photoswitchable ag...

journal_title：Nature communications

authors： Laprell L,Repak E,Franckevicius V,Hartrampf F,Terhag J,Hollmann M,Sumser M,Rebola N,DiGregorio DA,Trauner D

更新日期：2015-08-27 00:00:00

abstract：:Under pathophysiological conditions in adults, endothelial cells (ECs) sprout from pre-existing blood vessels to form new ones by a process termed angiogenesis. During embryonic development, Apelin (APLN) is robustly expressed in vascular ECs. In adult mice, however, APLN expression in the vasculature is significantly...

journal_title：Nature communications

authors： Liu Q,Hu T,He L,Huang X,Tian X,Zhang H,He L,Pu W,Zhang L,Sun H,Fang J,Yu Y,Duan S,Hu C,Hui L,Zhang H,Quertermous T,Xu Q,Red-Horse K,Wythe JD,Zhou B

更新日期：2015-01-19 00:00:00

abstract：:Osmoregulation is important for plant growth, development and response to environmental changes. SNF1-related protein kinase 2s (SnRK2s) are quickly activated by osmotic stress and are central components in osmotic stress and abscisic acid (ABA) signaling pathways; however, the upstream components required for SnRK2 a...

journal_title：Nature communications

authors： Lin Z,Li Y,Zhang Z,Liu X,Hsu CC,Du Y,Sang T,Zhu C,Wang Y,Satheesh V,Pratibha P,Zhao Y,Song CP,Tao WA,Zhu JK,Wang P

更新日期：2020-01-30 00:00:00

abstract：:Propagation behaviors of electromagnetic waves are governed by the equifrequency surface of the medium. Up to now, ordinary materials, including the medium exist in nature and the man-made metamaterials, always have an equifrequency surface (ellipsoid or hyperboloid) centered at zero k-point. Here we propose a new typ...

journal_title：Nature communications

authors： Chen WJ,Hou B,Zhang ZQ,Pendry JB,Chan CT

更新日期：2018-05-25 00:00:00

abstract：:Wild boar (Sus scrofa) drastically colonized mainland Eurasia and North Africa, most likely from East Asia during the Plio-Pleistocene (2-1Mya). In recent studies, based on genome-wide information, it was hypothesized that wild boar did not replace the species it encountered, but instead exchanged genetic materials wi...

journal_title：Nature communications

authors： Liu L,Bosse M,Megens HJ,Frantz LAF,Lee YL,Irving-Pease EK,Narayan G,Groenen MAM,Madsen O

更新日期：2019-04-30 00:00:00

abstract：:Insulin resistance is closely associated with obesity and is one of the earliest symptoms of type-2 diabetes. Endothelial cells are involved in the pathogenesis of insulin resistance through their role in insulin delivery and adipose tissue angiogenesis. Here we show that Ecscr (endothelial cell surface expressed chem...

journal_title：Nature communications

authors： Akakabe Y,Koide M,Kitamura Y,Matsuo K,Ueyama T,Matoba S,Yamada H,Miyata K,Oike Y,Ikeda K

更新日期：2013-01-01 00:00:00

abstract：:Strategies involving metastable phases have been the basis of the design of numerous alloys, yet research on metastable high-entropy alloys is still in its infancy. In dual-phase high-entropy alloys, the combination of local chemical environments and loading-induced crystal structure changes suggests a relationship be...

journal_title：Nature communications

authors： Chen S,Oh HS,Gludovatz B,Kim SJ,Park ES,Zhang Z,Ritchie RO,Yu Q

更新日期：2020-02-11 00:00:00

abstract：:Helitrons are eukaryotic DNA transposons that have profoundly affected genome variability via capture and mobilization of host genomic sequences. Defining their mode of action is therefore important for understanding how genome landscapes evolve. Sequence similarities with certain prokaryotic mobile elements suggest a...

journal_title：Nature communications

authors： Grabundzija I,Hickman AB,Dyda F

更新日期：2018-03-29 00:00:00

abstract：:The emergence of larger brains with large numbers of neurons is an evolutionary innovation in mammals and birds. However, the corresponding changes in cortical developmental programmes during amniote evolution are poorly understood. Here we examine the cortical development of Madagascar ground geckos, and report uniqu...

journal_title：Nature communications

authors： Nomura T,Gotoh H,Ono K

更新日期：2013-01-01 00:00:00

abstract：:Each skeletal muscle acquires its unique size before birth, when terminally differentiating myocytes fuse to form a defined number of multinucleated myofibres. Although mice in which the transcription factor Myogenin is mutated lack most myogenesis and die perinatally, a specific cell biological role for Myogenin has ...

journal_title：Nature communications

authors： Ganassi M,Badodi S,Ortuste Quiroga HP,Zammit PS,Hinits Y,Hughes SM

更新日期：2018-10-12 00:00:00

abstract：:A variety of flexible and stretchable electronics have been reported for use in flexible electronic devices or biomedical applications. The practical and wider application of such flexible electronics has been limited because commercial electronic components are difficult to be directly integrated into flexible stretc...

journal_title：Nature communications

authors： Jeong GS,Baek DH,Jung HC,Song JH,Moon JH,Hong SW,Kim IY,Lee SH

更新日期：2012-01-01 00:00:00

abstract：:Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reco...

journal_title：Nature communications

authors： Runge J,Petoukhov V,Donges JF,Hlinka J,Jajcay N,Vejmelka M,Hartman D,Marwan N,Paluš M,Kurths J

更新日期：2015-10-07 00:00:00

abstract：:The growing demand for lithium batteries with higher energy densities requires new electrode chemistries. Lithium metal is a promising candidate as the anode material due to its high theoretical specific capacity, negative electrochemical potential and favorable density. However, during cycling, low and uneven lithium...

journal_title：Nature communications

authors： Chen W,Hu Y,Lv W,Lei T,Wang X,Li Z,Zhang M,Huang J,Du X,Yan Y,He W,Liu C,Liao M,Zhang W,Xiong J,Yan C

更新日期：2019-10-31 00:00:00

abstract：:Stable water isotope records from Antarctica are key for our understanding of Quaternary climate variations. However, the exact quantitative interpretation of these important climate proxy records in terms of surface temperature, ice sheet height and other climatic changes is still a matter of debate. Here we report r...

journal_title：Nature communications

authors： Werner M,Jouzel J,Masson-Delmotte V,Lohmann G

更新日期：2018-08-30 00:00:00

abstract：:An invisibility cloak should completely hide an object from an observer, ideally across the visible spectrum and for all angles of incidence and polarizations of light, in three dimensions. However, until now, all such devices have been limited to either small bandwidths or have disregarded the phase of the impinging ...

journal_title：Nature communications

authors： Tsakmakidis KL,Reshef O,Almpanis E,Zouros GP,Mohammadi E,Saadat D,Sohrabi F,Fahimi-Kashani N,Etezadi D,Boyd RW,Altug H

更新日期：2019-10-24 00:00:00

abstract：:Diffuse Intrinsic Pontine Gliomas (DIPGs) are deadly paediatric brain tumours where needle biopsies help guide diagnosis and targeted therapies. To address spatial heterogeneity, here we analyse 134 specimens from various neuroanatomical structures of whole autopsy brains from nine DIPG patients. Evolutionary reconstr...

journal_title：Nature communications

authors： Nikbakht H,Panditharatna E,Mikael LG,Li R,Gayden T,Osmond M,Ho CY,Kambhampati M,Hwang EI,Faury D,Siu A,Papillon-Cavanagh S,Bechet D,Ligon KL,Ellezam B,Ingram WJ,Stinson C,Moore AS,Warren KE,Karamchandani J,Packer

更新日期：2016-04-06 00:00:00

abstract：:Researchers strive to produce nanoparticles with complexity in composition and structure. Although traditional spherical, cylindrical and membranous, or planar, nanostructures are ubiquitous, scientists seek more complicated geometries for potential functionality. Here we report the simple solution construction of mul...

journal_title：Nature communications

authors： Zhu J,Zhang S,Zhang K,Wang X,Mays JW,Wooley KL,Pochan DJ

更新日期：2013-01-01 00:00:00

abstract：:Nonsyndromic cleft lip with or without a cleft palate (NSCL/P) is among the most common human congenital birth defects and imposes a substantial physical and financial burden on affected individuals. Here, we conduct a case-control-based GWAS followed by two rounds of replication; we include six independent cohorts fr...

journal_title：Nature communications

authors： Sun Y,Huang Y,Yin A,Pan Y,Wang Y,Wang C,Du Y,Wang M,Lan F,Hu Z,Wang G,Jiang M,Ma J,Zhang X,Ma H,Ma J,Zhang W,Huang Q,Zhou Z,Ma L,Li Y,Jiang H,Xie L,Jiang Y,Shi B,Cheng J,Shen H,Wang L,Yang Y

更新日期：2015-03-16 00:00:00

abstract：:Myxofibrosarcoma (MFS) is a common adult soft tissue sarcoma characterized by an infiltrative growth pattern and a high local recurrence rate. Here we report the genetic and epigenetic landscape of MFS based on the results of whole-exome sequencing (N = 41), RNA sequencing (N = 29), and methylation analysis (N = 41), ...

journal_title：Nature communications

authors： Ogura K,Hosoda F,Arai Y,Nakamura H,Hama N,Totoki Y,Yoshida A,Nagai M,Kato M,Arakawa E,Mukai W,Rokutan H,Kawai A,Tanaka S,Shibata T

更新日期：2018-07-17 00:00:00

abstract：:There is increasing concern about potential long-term effects of antibiotics on children's health. Epidemiological studies have revealed that early-life antibiotic exposure can increase the risk of developing immune and metabolic diseases, and rodent studies have shown that administration of high doses of antibiotics ...

journal_title：Nature communications

authors： Leclercq S,Mian FM,Stanisz AM,Bindels LB,Cambier E,Ben-Amram H,Koren O,Forsythe P,Bienenstock J

更新日期：2017-04-04 00:00:00

abstract：:Metabolism is coordinated among tissues and organs via neuronal signals. Levels of circulating amino acids (AAs), which are elevated in obesity, activate the intracellular target of rapamycin complex-1 (mTORC1)/S6kinase (S6K) pathway in the liver. Here we demonstrate that hepatic AA/mTORC1/S6K signalling modulates sys...

journal_title：Nature communications

authors： Uno K,Yamada T,Ishigaki Y,Imai J,Hasegawa Y,Sawada S,Kaneko K,Ono H,Asano T,Oka Y,Katagiri H

更新日期：2015-08-13 00:00:00

abstract：:Brain oscillations reflect pattern formation of cell assemblies' activity, which is often disturbed in neurological and psychiatric diseases like depression, schizophrenia and stroke. In the neurobiological analysis and treatment of these conditions, transcranial electric currents applied to the brain proved beneficia...

journal_title：Nature communications

authors： Soekadar SR,Witkowski M,Cossio EG,Birbaumer N,Robinson SE,Cohen LG

更新日期：2013-01-01 00:00:00

abstract：:Supported gold (Au) nanocatalysts have attracted extensive interests in the past decades because of their unique catalytic properties for a number of key chemical reactions, especially in (selective) oxidations. The activation of O2 on Au nanocatalysts is crucial and remains a challenge because only small Au nanoparti...

journal_title：Nature communications

authors： Zhang Y,Zhang J,Zhang B,Si R,Han B,Hong F,Niu Y,Sun L,Li L,Qiao B,Sun K,Huang J,Haruta M

更新日期：2020-01-28 00:00:00

abstract：:Foxg constitutes a regulatory loop with Fgf8 and plays an important role in the development of anterior placodes and the telencephalon in vertebrate embryos. Ascidians, which belong to Tunicata, the sister group of vertebrates, develop a primitive placode-like structure at the anterior boundary of the neural plate, bu...

journal_title：Nature communications

authors： Liu B,Satou Y

更新日期：2019-10-29 00:00:00