Abstract：
:This is the first report regarding the characterization of the new synthetic cannabinoid 4F-MDMB-BINACA. 4F-MDMB-BINACA was first analytically confirmed in seized drug material using gas chromatography-mass spectrometry (GC-MS), liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF), and nuclear magnetic resonance (NMR) spectroscopy. Subsequent to this characterization, 4F-MDMB-BINACA was detected in biological specimens collected as part of forensically relevant casework, including medicolegal death investigations and drug impaired driving investigations, from a variety of regions in the United States. Further analysis of biological specimens resulted in the identification of the metabolites 4F-MDMB-BINACA 3,3-dimethylbutanoic acid and 4-OH-MDMB-BINACA. 4F-MDMB-BINACA is appearing with increasing frequency as a contributory factor in deaths, creating morbidity and mortality risks for drug users. Laboratories must be aware of its presence and impact, incorporating 4F-MDMB-BINACA into workflows for detection and confirmation.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Krotulski AJ,Mohr ALA,Kacinko SL,Fogarty MF,Shuda SA,Diamond FX,Kinney WA,Menendez MJ,Logan BKdoi
10.1111/1556-4029.14101subject
Has Abstractpub_date
2019-09-01 00:00:00pages
1451-1461issue
5eissn
0022-1198issn
1556-4029journal_volume
64pub_type
杂志文章abstract：:Invasive fungal infections are a leading cause of morbidity and mortality in immunocompromised patients, especially in cases requiring a prolonged stay in the intensive care unit. A total of 99 yeast strains were isolated from 42 postmortem cases. In this study, virulence factors and antifungal susceptibility of these...
journal_title：Journal of forensic sciences
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doi：10.1111/1556-4029.13089
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abstract：:Weight is often one of the few recoverable data when analyzing human cremains but references are still rare, especially for European populations. Mean weights for skeletal remains were thus documented for Portuguese modern cremations of both recently deceased individuals and dry skeletons, and the effect of age, sex, ...
journal_title：Journal of forensic sciences
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doi：10.1111/1556-4029.12167
更新日期：2013-09-01 00:00:00
abstract：:A rare case of colchicine poisoning resulting from accidental ingestion of meadow saffron (Colchicun Autumnale) is reported. The plant can frequently be found in the woods of the Northern Hemisphere (1), also in Japan. A 48-year-old male was admitted to hospital complaining of vomiting, nausea and diarrhea following i...
journal_title：Journal of forensic sciences
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更新日期：2002-11-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2007.00566.x
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abstract：:Domestic homicide is the most extreme form of domestic violence and one of the most common types of homicide. The objective was to examine differences between spontaneous domestic homicide and nondomestic homicide offenders regarding demographics, psychiatric history, crime characteristics, and neuropsychological stat...
journal_title：Journal of forensic sciences
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doi：10.1111/1556-4029.12908
更新日期：2016-01-01 00:00:00
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journal_title：Journal of forensic sciences
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doi：
更新日期：2004-01-01 00:00:00
abstract：:An elevated serum tryptase concentration is considered a specific marker for systemic mast cell activation, a central feature of anaphylaxis. However, in some cases of acute cardiovascular death, high concentrations of serum tryptase are also observed. We compared the postmortem serum tryptase concentrations in 74 cas...
journal_title：Journal of forensic sciences
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journal_title：Journal of forensic sciences
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doi：10.1111/j.1556-4029.2006.00159.x
更新日期：2006-07-01 00:00:00
abstract：:This study was designed to determine the effects of various environmental factors on the deoxyribonucleic acid (DNA) obtained from dental pulp. Extracted teeth were subjected to the following conditions: varying pH (3,7,10); temperature (4 degrees C, 25 degrees C, 37 degrees C, incineration); humidity (20%, 66%, 98%);...
journal_title：Journal of forensic sciences
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journal_title：Journal of forensic sciences
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doi：10.1111/1556-4029.12607
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journal_title：Journal of forensic sciences
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-11-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01653.x
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：:Determination of sex of unknown skeleton remains is the most important step in the identification process. Racial and regional differences in the populations create and maintain specificity in their dimorphic characteristics. Moreover, considering continued secular changes in the population structure, constant revisio...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2011.01885.x
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abstract：:Allele frequencies for the locus D1S80 were determined in African American, Caucasian, Southeastern Hispanic, Southwestern Hispanic, and Oriental sample populations using the polymerase chain reaction and subsequent electrophoresis and silver staining of the amplified products. Due to the presence of anodal and cathod...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Mitragyna speciosa (MS), a plant commonly known as kratom, is a widely used "legal high" opiate alternative for pain relief. DNA extracted from MS and 26 additional plant species was amplified by PCR using primers targeting the strictosidine beta-D-glucosidase (SGD) and secologanin synthase 2 (SLS2) genes and detected...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.14167
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:A simple method using purge-and-trap gas chromatography/mass spectrometry (P&T-GC/MS) for forensic examination of oil stains was studied. Carboxylic acids, chosen as target components for discrimination of oil samples, were extracted from stains with ether, methyl esterified by tetramethylammonium hydroxide, and analy...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：:High-energy synchrotron radiation x-ray fluorescence spectrometry (SR-XRF) utilizing 116 keV x-rays was used to characterize titanium dioxide pigments (rutile) and automotive white paint fragments for forensic examination. The technique allowed analysis of K lines of 9 trace elements in 18 titanium dioxide pigments (r...
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journal_title：Journal of forensic sciences
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doi：
更新日期：1996-07-01 00:00:00
abstract：:Analyses of saw marks in bone may yield important information about the class characteristics of saws used in postmortem dismemberments, yet little research has been directed at identifying saws' individualizing characteristics. This study adds to existing saw mark analysis methodologies by examining wear-related feat...
journal_title：Journal of forensic sciences
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1978-04-01 00:00:00
abstract：:Estimating the time since death of the deceased is a main goal in forensic investigations, but this can be challenging due to contradictory results derived from different investigations at the scene of death. We present a case of a 78-year-old woman, found dead in a small forest with broad-leaved trees, whose husband ...
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journal_title：Journal of forensic sciences
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doi：
更新日期：2005-09-01 00:00:00
abstract：:When deaths occur in water, soft tissue decomposes after a temperature-dependent period, making DNA identification dependent on bone. This study examined the effects of water on bone DNA purity and quantity, and determined the best of three extraction methods for isolating DNA. The organic phenol-chloroform method con...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13792
更新日期：2018-11-01 00:00:00
abstract：:New procedures, tailored after such court decisions as Rogers v. Commissioner of the Department of Mental Health, have restricted the doctor's ability to treat psychiatric inpatients with psychotropic medication and have increased the protection of a competent patient's right to refuse. This study investigates how the...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Chorionic villus sampling (CVS), prior to pregnancy termination (pre-termination CVS), is suggested as a tool for forensic paternity testing. Unlike the abortion material, which consists of ruptured tissues of fetal and maternal origin, extra-embryonic membranes obtained through CVS can provide an uncontaminated sourc...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:This study extends previous work on the sorption of explosives to the hair matrix. Specifically, we have studied the interaction of 2,4,6-trinitrotoluene (TNT) and triacetone triperoxide (TATP) as a function of chemical pretreatment with acetonitrile, neutral and alkaline hydrogen peroxide, methanolic KOH and potassiu...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2011.02020.x
更新日期：2012-05-01 00:00:00
