Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement.

abstract：:Colorectal cancer, the third most commonly diagnosed cancer, is a lifestyle disease where diet and gut microbiome contribute intricately in its initiation and progression. Prophylactic bio-interventions mainly probiotics offer an alternate approach towards reducing or delaying its progression. Therefore, the present s...

journal_title：Scientific reports

authors： Chandel D,Sharma M,Chawla V,Sachdeva N,Shukla G

更新日期：2019-10-14 00:00:00

abstract：:Oxidative stress (OS), mitochondrial dysfunction, and dysregulation of alpha-synuclein (aSyn) homeostasis are key pathogenic factors in Parkinson's disease. Nevertheless, the role of aSyn in mitochondrial physiology remains elusive. Thus, we addressed the impact of aSyn specifically on mitochondrial response to OS in ...

journal_title：Scientific reports

authors： Menges S,Minakaki G,Schaefer PM,Meixner H,Prots I,Schlötzer-Schrehardt U,Friedland K,Winner B,Outeiro TF,Winklhofer KF,von Arnim CA,Xiang W,Winkler J,Klucken J

更新日期：2017-02-22 00:00:00

abstract：:An image fiber-based miniature suspended solid sensor has been demonstrated. The diameter of the sensor is only a few millimeters. A superhydrophobic material is coated on the end of the image fiber to avoid the adsorption of suspended solids and bubbles. Multiple parameters, including mass concentration, morphology a...

journal_title：Scientific reports

authors： Qi P,Lin L,Huang R,Zhao S,Tian H,Li S,Zhang Q,Liu W

更新日期：2017-12-01 00:00:00

abstract：:A method is described for multi-residue, high-throughput determination of trace levels of 22 organochlorine pesticides (OCPs) and 5 pyrethroid pesticides (PYPs) in Chinese medicinal (CM) health wines using a QuEChERS (quick, easy, cheap, effective, rugged, and safe) based extraction method and gas chromatography-elect...

journal_title：Scientific reports

authors： Kong WJ,Liu QT,Kong DD,Liu QZ,Ma XP,Yang MH

更新日期：2016-02-17 00:00:00

abstract：:Prognosis of patients with advanced sarcoma after progression from FDA approved therapies remains grim. In this study, clinical outcomes of 100 patients with advanced sarcoma who received treatment on novel targeted therapy trials were evaluated. Outcomes of interest included best response, clinical benefit rate, prog...

journal_title：Scientific reports

authors： Subbiah V,Hess KR,Khawaja MR,Wagner MJ,Tang C,Naing A,Fu S,Janku F,Piha-Paul S,Tsimberidou AM,Herzog CE,Ludwig JA,Patel S,Ravi V,Benjamin RS,Meric-Bernstam F,Hong DS

更新日期：2016-10-17 00:00:00

abstract：:Familial hypercholesterolemia (FH) is an inherited disease of lipoprotein metabolism caused by a defect in the LDL receptor (LDLR) leading to severe hypercholesterolemia, and associated with an increased risk of coronary heart disease and myocardial infarction. We have developed a gene therapy protocol for FH using AA...

journal_title：Scientific reports

authors： Hytönen E,Laurema A,Kankkonen H,Miyanohara A,Kärjä V,Hujo M,Laham-Karam N,Ylä-Herttuala S

更新日期：2019-05-06 00:00:00

abstract：:An available pathway to prepare the ionized covalent organic nanosheets (iCONs) has been proposed by a metal-assisted aqueous-phase exfoliation route from covalent organic frameworks. The soluble and belt-shaped iCONs could immobilize a large quantity of proteins (2.73 mg/mg, BSA/iCONs) and hence serve as transporters...

journal_title：Scientific reports

authors： Kong W,Wan J,Namuangruk S,Guo J,Wang C

更新日期：2018-04-03 00:00:00

abstract：:We examined how plant-pollinator interactions were affected by time since habitat restoration and landscape connectivity by comparing plant-pollinator networks in restored, abandoned and continuously grazed semi-natural pastures in south-central Sweden. We measured richness of flowering plants and pollinators, and loc...

journal_title：Scientific reports

authors： Noreika N,Bartomeus I,Winsa M,Bommarco R,Öckinger E

更新日期：2019-10-29 00:00:00

abstract：:The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) has been counted on for conserving threatened marine fish since it regulates the commercial international trade of these species. Implementation of the international treaty for Mantas included on CITES Appendix II is challengin...

journal_title：Scientific reports

authors： Zeng Y,Wu Z,Zhang C,Meng Z,Jiang Z,Zhang J

更新日期：2016-11-23 00:00:00

abstract：:This study presents a modular-based implementation of augmented reality to provide an immersive experience in learning or teaching the planning phase, control system, and machining parameters of a fully automated work cell. The architecture of the system consists of three code modules that can operate independently or...

journal_title：Scientific reports

authors： Pai YS,Yap HJ,Md Dawal SZ,Ramesh S,Phoon SY

更新日期：2016-06-07 00:00:00

abstract：:Freeze-thaw cycles are predicted to increase in cold temperate regions. The potential influence of the interactions of freeze-thaw cycles and agrochemicals on the release of Cd into river water is unknown. In this study, the interactions of freeze-thaw cycles and chlorpyrifos (FC) on Cd mobility in soils were analysed...

journal_title：Scientific reports

authors： Wang F,Ouyang W,Hao F,Jiao W,Shan Y,Lin C

更新日期：2016-06-02 00:00:00

abstract：:To improve the performance of solar photovoltaic devices one should mitigate three types of losses: optical, electrical and thermal. However, further reducing the optical and electrical losses in modern photovoltaic devices is becoming increasingly costly. Therefore, there is a rising interest in minimizing the therma...

journal_title：Scientific reports

authors： Vaillon R,Dupré O,Cal RB,Calaf M

更新日期：2018-09-03 00:00:00

abstract：:Zeolites/molecular sieves with uniform, molecular-sized pores are important for many adsorption-based separation processes. Pore size gaps, however, exist in the current zeolite family. This leads to a great challenge of separating molecules with size differences at ~0.01 nm level. Here, we report a novel concept, por...

journal_title：Scientific reports

authors： Song Z,Huang Y,Xu WL,Wang L,Bao Y,Li S,Yu M

更新日期：2015-09-11 00:00:00

abstract：:From 2010 to 2012, large outbreaks of EV-A71-related- hand foot and mouth disease (HFMD) occurred annually in China. Some cases had neurological complications and were closely associated with fatal cardiopulmonary collapse, but not all children with central nervous system (CNS) involvement demonstrated a poor prognosi...

journal_title：Scientific reports

authors： Long L,Xu L,Xiao Z,Hu S,Luo R,Wang H,Lu X,Xu Z,Yao X,Zhou L,Long H,Gong J,Song Y,Zhao L,Luo K,Zhang M,Feng L,Yang L,Sheng X,Fan X,Xiao B

更新日期：2016-03-22 00:00:00

abstract：:As the global prevalence of childhood obesity continues to rise, researchers and clinicians have sought to develop more effective and personalized intervention techniques. In doing so, obesity interventions have expanded beyond the traditional context of nutrition to address several facets of a child's life, including...

journal_title：Scientific reports

authors： Feldman K,Solymos GMB,de Albuquerque MP,Chawla NV

更新日期：2019-12-11 00:00:00

abstract：:Studies have assessed individual components of a western diet, but no study has assessed the long-term, cumulative effects of a western diet on aging and Alzheimer's disease (AD). Therefore, we have formulated the first western-style diet that mimics the fat, carbohydrate, protein, vitamin and mineral levels of wester...

journal_title：Scientific reports

authors： Graham LC,Harder JM,Soto I,de Vries WN,John SW,Howell GR

更新日期：2016-02-18 00:00:00

abstract：:Improving surface sensitivities of nanostructure-based plasmonic sensors is an important issue to be addressed. Among the SPR measurements, the wavelength interrogation is commonly utilized. We proposed using blue-shifted surface plasmon mode and Fano resonance, caused by the coupling of a cavity mode (angle-independe...

journal_title：Scientific reports

authors： Lee KL,Chang CC,You ML,Pan MY,Wei PK

更新日期：2018-06-27 00:00:00

abstract：:The reliable identification of diffuse large B-cell lymphoma (DLBCL)-specific targets owns huge implications for its diagnosis and treatment. Long non-coding RNAs (lncRNAs) are implicated in DLBCL pathogenesis; however, circulating DLBCL-related lncRNAs are barely investigated. We investigated plasma lncRNAs; HOTAIR, ...

journal_title：Scientific reports

authors： Senousy MA,El-Abd AM,Abdel-Malek RR,Rizk SM

更新日期：2021-01-22 00:00:00

abstract：:Human KHDRBS1/Sam68 is an oncogenic splicing factor involved in signal transduction and pre-mRNA splicing. We explored the molecular mechanism of KHDRBS1 to be a prognostic marker in four different cancers. Within specific cancer, including kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), acut...

journal_title：Scientific reports

authors： Sumithra B,Saxena U,Das AB

更新日期：2019-07-31 00:00:00

abstract：:The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally occurring compound with cumulative evidence of anti-cancer properties. In this study, we assessed the chemomodulatory potential of TQ to...

journal_title：Scientific reports

authors： Bashmail HA,Alamoudi AA,Noorwali A,Hegazy GA,AJabnoor G,Choudhry H,Al-Abd AM

更新日期：2018-08-03 00:00:00

abstract：:Salvia miltiorrhiza Bunge, which contains tanshinones and phenolic acids as major classes of bioactive components, is one of the most widely used herbs in traditional Chinese medicine. Production of tanshinones and phenolic acids is enhanced by methyl jasmonate (MeJA). Transcription factor MYC2 is the switch of jasmon...

journal_title：Scientific reports

authors： Zhou Y,Sun W,Chen J,Tan H,Xiao Y,Li Q,Ji Q,Gao S,Chen L,Chen S,Zhang L,Chen W

更新日期：2016-03-07 00:00:00

abstract：:Overuse of nitrogen (N) fertilizer has led to low N use efficiency (NUE) and high N loss in single rice cropping systems in southeast China. Application of controlled-release urea (CRU) is considered as an effective N fertilizer practice for improving crop yields and NUE. Here, field experiments were conducted during ...

journal_title：Scientific reports

authors： Chen Z,Wang Q,Ma J,Zou P,Jiang L

更新日期：2020-06-26 00:00:00

abstract：:Pyramidal neurons in the rodent hippocampus exhibit spatial tuning during spatial navigation, and they are reactivated in specific temporal order during sharp-wave ripples observed in quiet wakefulness or slow wave sleep. However, analyzing representations of sleep-associated hippocampal ensemble spike activity remain...

journal_title：Scientific reports

authors： Chen Z,Grosmark AD,Penagos H,Wilson MA

更新日期：2016-08-30 00:00:00

abstract：:Stylosanthes guianensis (Aubl.) Sw. is an economically important pasture and forage legume in tropical regions of the world. Genetic improvement of the crop can be enhanced through marker-assisted breeding. However, neither single nucleotide polymorphism (SNP) markers nor SNP-based genetic linkage map has been previou...

journal_title：Scientific reports

authors： Tang YQ,Xia ZQ,Ding ZT,Ding YC,Liu Z,Ma X,Liu JP

更新日期：2019-03-07 00:00:00

abstract：:Mild cognitive impairment (MCI) is a precursor phase of Alzheimer's disease (AD). As current treatments may be effective only at the early stages of AD, it is important to track MCI patients who will convert to AD. The aim of this study is to develop a high performance semi-mechanism based approach to predict the conv...

journal_title：Scientific reports

authors： Liu H,Zhou X,Jiang H,He H,Liu X,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-07 00:00:00

abstract：:Web search tools are widely used by the general public to obtain health-related information, and analysis of search data is often suggested for public health monitoring. We analyzed popularity of searches related to smell loss and taste loss, recently listed as symptoms of COVID-19. Searches on sight loss and hearing ...

journal_title：Scientific reports

authors： Asseo K,Fierro F,Slavutsky Y,Frasnelli J,Niv MY

更新日期：2020-11-25 00:00:00

abstract：:Vertically aligned radial-junction solar cell designs offer potential improvements over planar geometries, as carrier generation occurs close to the junction for all absorption depths, but most production methods still require a single crystal substrate. Here, we report on the fabrication of such solar cells from poly...

journal_title：Scientific reports

authors： Martinsen FA,Smeltzer BK,Nord M,Hawkins T,Ballato J,Gibson UJ

更新日期：2014-09-04 00:00:00

abstract：:Across boundary currents, zooplankton are subject to strong oceanographic gradients and hence strong selective pressures. How such gradients interact with the speciation process of pelagic organisms is still poorly understood in the open ocean realm. Here we report on genetic diversity within the pelagic copepod Pleur...

journal_title：Scientific reports

authors： González CE,Goetze E,Escribano R,Ulloa O,Victoriano P

更新日期：2020-01-24 00:00:00

abstract：:For many malignancies, inflammation-based scores correlate with survival. The neutrophil-to-lymphocyte ratio (NLR) and prognostic nutritional index (PNI) are immunonutritional indices associated with postoperative outcomes in patients with hepatocellular carcinoma (HCC). We evaluated whether a combined preoperative NL...

journal_title：Scientific reports

authors： Liu C,Li L,Lu WS,Du H,Yan LN,Yang JY,Wen TF,Zeng GJ,Jiang L,Yang J

更新日期：2017-10-24 00:00:00

abstract：:Crops have different strategies to acquire poorly-available soil phosphorus (P) which are dependent on their architectural, morphological, and physiological root traits, but their capacity to enhance P acquisition varies with the type of fertilizer applied. The objective of this study was to examine how P-acquisition ...

journal_title：Scientific reports

authors： Nobile C,Houben D,Michel E,Firmin S,Lambers H,Kandeler E,Faucon MP

更新日期：2019-10-16 00:00:00