Abstract:
OBJECTIVES:To investigate the association between the number of metastases to the spine and survival in patients with metastatic spinal cord compression (MSCC), as well as the prognosis difference between patients with solitary spinal metastasis (SSM) and multiple spinal metastases (MSM). METHODS:Three institutional databases were searched to identify all patients who had undergone spinal surgery for metastatic spinal tumors between March 2002 and June 2010. As well as age and gender, preoperative medical conditions were collected from medical records, including primary tumor, preoperative Frankel score, other bone metastases, preoperative Karnofsky performance status (KPS), number of involved vertebrae, pathological fracture metastasis site, serum albumin, sphincter dysfunction and the time of developing motor deficits before surgery. Survival data were obtained from medical records or via telephone follow-ups. Univariate and multivariate predictors of overall survival for each group were assessed using the Cox proportional hazards model. RESULTS:The median postoperative survival time was 6.0 ± 0.6 months (95% confidence interval [CI] 4.8-7.2) in patients with SSM and 7.0 ± 1.0 months (95% CI 5.1-8.9) in patients with MSM (P = 0.238). The difference in survival was not significant between groups. Furthermore, univariate analysis showed that the number of spinal metastases had no significant association with survival (P = 0.075). Primary tumor (P = 0.004) and preoperative KPS (P < 0.001) were independent prognostic factors in the whole cohort; primary tumor (P = 0.020), time of developing motor deficit (P = 0.041) and preoperative KPS (P = 0.038) were independent prognostic factors in patients with SSM; while preoperative KPS (P = 0.001) and serum album level (P < 0.001) were independent prognostic factors in patients with MSM. CONCLUSION:The number of spinal metastases has not proven to be useful in predicting the prognosis for patients with MSCC. Consequently, more aggressive operations should be considered for patients with multiple spinal metastases.
journal_name
Orthop Surgjournal_title
Orthopaedic surgeryauthors
Lun DX,Xu LN,Wang F,Yang XG,Yu XC,Zhang GC,Hu YCdoi
10.1111/os.12470subject
Has Abstractpub_date
2019-06-01 00:00:00pages
443-450issue
3eissn
1757-7853issn
1757-7861journal_volume
11pub_type
杂志文章abstract:OBJECTIVE:To assess the difference between drainage and non-drainage after total hip arthroplasty (THA) in Chinese subjects by evaluating post-operative complications and joint function. METHODS:One hundred and sixty-eight patients undergoing THA were randomly allocated into drainage (83 patients) and non-drainage gro...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/os.12092
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To review the long-term clinical results after revision surgery and the relationship between the different clinical variables involved with a failed total knee arthroplasty (TKA) and its evolution to provide a better understanding of the current treatment methods. METHODS:The present study involved 89 subjec...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12593
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:This research aimed to investigate the relative level of Runt-related transcription factor 2 (RUNX2) in giant cell tumor of bone (GCTB). Through the histopathological similarities between osteoporosis and GCTB, the biological functions of exogenous RUNXS were demonstrated in GCTB cell lines. This generated a...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12568
更新日期:2020-04-01 00:00:00
abstract::To observe the morphology character of the anterior epidural space at the L4-5 disc level and to provide an anatomical basis for safely and accurately performing a percutaneous endoscopic lumbar discectomy (PELD). Fifty-five cases with L5 S1 lumbar disc herniation were included in this study, and cases with L4-5 disea...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12325
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of residual varus and valgus deformity on the stress distribution of the knee joint after tibial fracture malunion. METHODS:Fourteen adult cadaver specimens were selected to establish the models of tibial fractures, which were fixed subsequently at neutral position (anatomical reduc...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12668
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:Acute hematogenous infection is a devastating complication that can occur after total knee arthroplasty (TKA). The best strategies for management of this infection remain controversial. Two-stage revision has been well described as the gold standard for the management of chronic late infections. However, ther...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12297
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To introduce a microsurgical suture technique for repair of dural tear under posterior lumbar disk scope. METHODS:Micro endoscopic discectomy was performed on a 26-year-old male under local anesthesia. During the operation, an irregular tear of about 1.0 cm was inadvertently made in the dura.The cauda equina...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2011.00135.x
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The arcuate foramen is a complete or partial bony bridge over the vertebral artery groove of atlas. The mechanism of the arcuate foramen is not clearly understood. Omission of the arcuate foramen sometimes causes lethal iatrogenic injury during spinal surgery. CASE PRESENTATION:We describe a patient who was...
journal_title:Orthopaedic surgery
pub_type:
doi:10.1111/os.12868
更新日期:2020-12-03 00:00:00
abstract:OBJECTIVE:Fusobacterium nucleatum is an anaerobic gram-negative bacilli that is one of the oral and other mucosal surface microbiota. It involves a wide range of human diseases and was first found in periodontal diseases, but reports of bone-related infections caused by F. nucleatum are rare, especially periprosthetic ...
journal_title:Orthopaedic surgery
pub_type:
doi:10.1111/os.12844
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To compare the superior-level facet joint violations (FJV) between robot-assisted (RA) percutaneous pedicle screw placement and conventional open fluoroscopic-guided (FG) pedicle screw placement in a prospective cohort study. METHODS:This was a prospective cohort study without randomization. One-hundred pati...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12534
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Femoral avulsion fracture of the posterior cruciate ligament (PCL) in association with meniscus tear is extremely rare in children, and similar cases are not available in the existing literature. CASE PRESENTATION:In this paper, we present a case of a 9-year-old boy treated by an arthroscopic repair techniq...
journal_title:Orthopaedic surgery
pub_type:
doi:10.1111/os.12636
更新日期:2020-04-01 00:00:00
abstract::Diaphyseal defects in long bones of extremities following segmental resection are very common in the clinic, and reconstruction remains a great challenge. Although there are many treatments for diaphyseal defects at present, reconstruction with an intercalary endoprosthesis may be an optimal method. We demonstrate a s...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12391
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To investigate the utility and medium-term results of a new intra-operative classification system for distal tibiofibular syndesmosis injury in ankle fractures. METHODS:Between January 2010 and January 2015, 116 patients diagnosed with displaced closed Weber B and C ankle fractures were treated in our depart...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12355
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Occipitocervical fusion (OCF) is an effective treatment for instability of occipitocervical junction (OCJ). The occipital condyle screw serves as a novel surgical technique for occipitocervical fixation. However, the intraoperative procedures for the occipital condyle screw technique have relied on surgeons'...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12700
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:Although contributions to sagittal alignment have been characterized for anterior, posterior and transforaminal lumbar interbody fusion, sagittal alignment after lateral transpsoas interbody fusion (LTIF) has not yet been characterized. This study examined the ability of LTIF to restore lumbar lordosis and id...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2012.00175.x
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To describe the technique and analyze the outcomes of joint-preserving surgical treatments which included anatomical reconstruction or alignment correction for talar malunions or nonunions, and avoid development of degenerative changes in the adjacent joints. METHODS:Eight patients who had painful talar malu...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12301
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To develop a novel screw positioning method to improve the treatment of unstable thoracolumbar fractures. METHODS:A total of 72 patients with unstable thoracolumbar fractures who were treated with anterior screw-rod interfixation from January 2011 to October 2015 were included in this clinical study. Those p...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12506
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To investigate the changes of inflammatory factors and bone metabolism markers in postmenopausal women with H-type hypertension and to assess the relationship between them. METHODS:Postmenopausal women who were diagnosed with osteoporosis were selected as observation objects. Participants were divided into t...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12567
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:To determine whether the rates of postoperative complications, rate of readmission, cumulative transfusion volume, and length of stay (LOS) differ between simultaneous total hip arthroplasty (THA) and staged bilateral THA and to assess whether the length of the interval between staged procedures influences s...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12617
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:We analyzed chondrosarcomas in long bones to assess whether Grade I and II chondrosarcomas should both be grouped as low grade malignant tumors (musculoskeletal Tumor Society Stage I or Stage II), and to explore rational surgical treatment for Grade I and II chondrosarcomas. METHODS:We retrospectively review...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2009.00020.x
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to identify the common microorganisms causing PJI as well as the drug-resistant spectrum for each microorganism, to help orthopaedic surgeons to choose appropriate antibiotics. METHOD:One hundred and sixty patients who suffered from failure of primary or revision total hip or knee ar...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12394
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:The prevention and treatment of the common complication of cerebrospinal fluid leakage (CSFL) during anterior approach cervical spine surgery for severe ossification of the posterior longitudinal ligament (OPLL) is documented. METHOD:A retrospective analysis of 47 patients with severe cervical OPLL aged 39 t...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12007
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To investigate the efficacy and safety of tranexamic acid (TXA) in the reduction of bleeding and the need for transfusion in elderly intertrochanteric fracture patients. METHODS:A total of 100 patients with intertrochanteric fractures undergoing surgery were enrolled and randomly allocated to the TXA group i...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/os.12511
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To investigate the influence of preoperative osteopenia/osteoporosis on periprosthetic bone loss after total hip arthroplasty (THA) and the efficiency of zoledronate (ZOL) treatment in periprosthetic bone preservation. METHODS:This multicenter, prospective cohort study was conducted in four centers between A...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,多中心研究
doi:10.1111/os.12513
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the functional outcomes of arthroscopic anatomical repair of anterior talofibular ligament (ATFL) in the treatment of chronic lateral ankle instability (CLAI) during medium- and long-term follow-up. METHODS:From September 2014 to August 2017, the data of 37 patients (23 males, 14 females; 12 left...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12651
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:Knee arthroscopy is a commonly performed orthopedic procedure. Post-operatively, adequate pain relief reduces the surgical stress response and patient's morbidity and facilitates rehabilitation. The analgesic effect of dexmedetomidine (2 μg/kg body weight) as an adjunct to ropivacaine in knee arthroscopic kne...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/os.12182
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To investigate the outcomes of total knee arthroplasty (TKA) in patients with a prior femoral or tibial fracture, and identify the risk factors for surgical site complications and reoperations. METHODS:Seventy-one TKAs performed in 71 patients with a prior tibial or femoral fracture between January 2005 and ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12610
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To assess whether computed tomography (CT)-based 3-dimensional (3D) computerized pre-operative planning is accurate and reliable in patients with high-riding dislocation developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA). METHODS:Between September 2009 and February 2011, a prosp...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12099
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the mid-term outcomes of transoral atlantoaxial reduction plate (TARP) internal fixation for the treatment of irreducible atlantoaxial dislocation. METHODS:From April 2003 to April 2005, 31 patients with irreducible atlantoaxial dislocation were treated with TARP internal fixation. The average ag...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2010.00077.x
更新日期:2010-05-01 00:00:00
abstract::The authors describe a hybrid technique that involves a combination of open decompression and posterior lumbar interbody fusion (PLIF) and percutaneously inserted pedicle screws. This technique allows performance of PLIF and decompression via a midline incision and approach without compromising operative time and visu...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12042
更新日期:2013-05-01 00:00:00