Abstract:
OBJECTIVE:To investigate the changes of inflammatory factors and bone metabolism markers in postmenopausal women with H-type hypertension and to assess the relationship between them. METHODS:Postmenopausal women who were diagnosed with osteoporosis were selected as observation objects. Participants were divided into three groups: only osteoporosis group (osteoporosis group), hypertension combined with osteoporosis group (hypertension group), and H-type hypertension combined with osteoporosis group (H-type hypertension group). The changes in bone mineral density and bone metabolic markers (osteocalcin [OC], procollagen type I N-terminal propeptide (PINP), and C-terminal cross-linking telopeptide of type I collagen [CTX]) and inflammatory factors (interleukin-6 [IL-6] and tumor necrosis factor-α [TNF-α]) were compared among three groups. RESULTS:In the hypertension group and the H-type hypertension group, the bone mineral density of the lumbar spine (0.647 ± 0.038 vs 0.638 ± 0.034 vs 0.668 ± 0.047, P < 0.05) and the femoral neck (0.567 ± 0.047 vs 0.552 ± 0.053 vs 0.618 ± 0.059, P < 0.05) was significantly lower than that in the osteoporosis group. The concentrations of CTX (266.61 ± 64.65 vs 293.09 ± 72.34 vs 235.48 ± 62.85, P < 0.05), IL-6 (44.36 ± 6.45 vs 48.05 ± 8.04 vs 39.06 ± 7.95, P < 0.05) and TNF-α (30.53 ± 6.28 vs 34.52 ± 7.15 vs 28.66 ± 6.19, P < 0.01) in the hypertension group and in the H-type hypertension group were significantly higher than those in the osteoporosis group. The concentrations of OC (30.59 ± 6.43 vs 27.10 ± 6.51, P < 0.05) and PINP (36.36 ± 6.16 vs 33.16 ± 6.77, P < 0.05) in the H-type hypertension group were increased dramatically. The concentration of CTX was positively correlated with the concentration of IL-6 (r = 0.587, P < 0.01) and TNF-α (r = 0.474, P < 0.01) and negatively related with the concentration of OC (r = -0.591, P < 0.01) and PINP (r = -0.646, P < 0.01) and the bone mineral density of the lumbar spine (r = -0.470, P < 0.01) and the femoral neck (r = -0.509, P < 0.01). CONCLUSION:Higher concentration of serum CTX is found in postmenopausal women with H-type hypertension, which is positively correlated with inflammatory factors. Besides, H-type hypertension could further enhance the activity of osteoclasts and increase the expressions of inflammatory factors, resulting in the aggravation of osteoporosis.
journal_name
Orthop Surgjournal_title
Orthopaedic surgeryauthors
Chen YN,Wei P,Yu Bs Jdoi
10.1111/os.12567subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1135-1141issue
6eissn
1757-7853issn
1757-7861journal_volume
11pub_type
杂志文章abstract:OBJECTIVE:To review the long-term clinical results after revision surgery and the relationship between the different clinical variables involved with a failed total knee arthroplasty (TKA) and its evolution to provide a better understanding of the current treatment methods. METHODS:The present study involved 89 subjec...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12593
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The arcuate foramen is a complete or partial bony bridge over the vertebral artery groove of atlas. The mechanism of the arcuate foramen is not clearly understood. Omission of the arcuate foramen sometimes causes lethal iatrogenic injury during spinal surgery. CASE PRESENTATION:We describe a patient who was...
journal_title:Orthopaedic surgery
pub_type:
doi:10.1111/os.12868
更新日期:2020-12-03 00:00:00
abstract:BACKGROUND:Femoral avulsion fracture of the posterior cruciate ligament (PCL) in association with meniscus tear is extremely rare in children, and similar cases are not available in the existing literature. CASE PRESENTATION:In this paper, we present a case of a 9-year-old boy treated by an arthroscopic repair techniq...
journal_title:Orthopaedic surgery
pub_type:
doi:10.1111/os.12636
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:To analyze the curative effect of TiRobot surgical robotic navigation and location system-assisted percutaneous sacroiliac screw fixation and percutaneous sacroiliac screw by traditional fluoroscopy, and to summarize the safety and benefits of TiRobot. METHODS:A total of 91 patients with pelvic posterior ri...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12461
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To establish a three-dimensional finite element model of the L(5)/S(1) motion segment with percutaneous axial lumbosacral screw and analyze the biomechanical stress on the screw. METHODS:With the help of related software and the Mechanical Virtual Human of China, a three-dimensional finite element model was ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2010.00088.x
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of surgery and rehabilitation on patients undergoing total knee arthroplasty (TKA). METHODS:Twelve patients and 12 healthy controls were enrolled and their clinical scores evaluated by a doctor. Gait data, including walking velocity, stride length, single support time, foot fall and s...
journal_title:Orthopaedic surgery
pub_type: 临床试验,杂志文章
doi:10.1111/os.12270
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To compare the clinical efficacy of intramedullary nail fixation for intertrochanteric fractures assisted by orthopaedic robot navigation and the traditional intramedullary nail fixation in elderly patients, and to investigate the application advantages of intramedullary nail fixation for femoral intertrochan...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12447
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:Knee arthroscopy is a commonly performed orthopedic procedure. Post-operatively, adequate pain relief reduces the surgical stress response and patient's morbidity and facilitates rehabilitation. The analgesic effect of dexmedetomidine (2 μg/kg body weight) as an adjunct to ropivacaine in knee arthroscopic kne...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/os.12182
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and safety of the postoperative long-term effect of the treatment of single-level cervical spondylosis through anterior cervical discectomy and fusion (ACDF) and artificial cervical disc replacement (ACDR). METHODS:This is a retrospective contrastive study, which was conducted for the...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12634
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:To determine whether the rates of postoperative complications, rate of readmission, cumulative transfusion volume, and length of stay (LOS) differ between simultaneous total hip arthroplasty (THA) and staged bilateral THA and to assess whether the length of the interval between staged procedures influences s...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12617
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and safety of hip replacement and intramedullary nails for treating unstable intertrochanteric fractures in elderly patients. METHODS:Randomized clinical trials (RCTs) to compare hip replacement with intramedullary nail in the management of elderly patients with unstable intertrochan...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,meta分析
doi:10.1111/os.12532
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcome of computed tomography (CT)-guided percutaneous puncture and local chemotherapy for tuberculosis (TB) of the lumbar or lumbosacral spine. METHODS:From January 2002 to August 2006, 49 patients with lumbar or lumbosacral spinal TB in whom conservative treatment had failed were treated b...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2009.00060.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:A series of constant anatomical structures were used as guide targets for screw placement to improve the accuracy of cortical screw placement and reduce surgical injury and fluoroscopy radiation. The most commonly used angles and distances between the cortical bone screw insertion point and the lateral margi...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12775
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of timing of surgery on clinical results and perioperative complications in pediatric patients with Gartland III type supracondylar humeral fractures without neurovascular compromise. METHODS:Eighty-six consecutive children treated surgically at our hospital from April 2005 to June ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2011.00153.x
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:Accurate understanding of the cause of the underlying pathology in children with diastrophic dysplasia would help in designing targeted management of their locomotion. METHODS:Diastrophic dysplasia was diagnosed in twelve patients (nine girls and three boys; age range 1-14 years), all of whom presented with ...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12146
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To assess whether computed tomography (CT)-based 3-dimensional (3D) computerized pre-operative planning is accurate and reliable in patients with high-riding dislocation developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA). METHODS:Between September 2009 and February 2011, a prosp...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12099
更新日期:2014-05-01 00:00:00
abstract::In the realm of orthopaedics, the terrible triad of the elbow is infamous, not simply because the prognosis is poor for most patients, but also, maybe to a greater extent, because the unique name of this malady attracts considerable attention and interest in both doctors and patients. The adjective terrible is bestowe...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,评审
doi:10.1111/os.12149
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To discuss the methods, timing and clinical outcomes of surgical treatment for open pilon fractures. METHODS:From April 2003 to July 2008, 28 patients with open pilon fractures were treated. All had type C fractures according to the Arbeitsgemeinschaft für osteosynthesefragen-Association for the Study of Int...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2010.00113.x
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To introduce an iliosacral screw fixation guide and evaluate its efficacy in fixation of sacroiliac joint fracture-dislocations. METHODS:Between January 2011 and May 2011, eight patients (five men, three women) with sacroiliac joint fracture-dislocation underwent percutaneous iliosacral screw fixation with t...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/j.1757-7861.2011.00162.x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To investigate the influence of preoperative osteopenia/osteoporosis on periprosthetic bone loss after total hip arthroplasty (THA) and the efficiency of zoledronate (ZOL) treatment in periprosthetic bone preservation. METHODS:This multicenter, prospective cohort study was conducted in four centers between A...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,多中心研究
doi:10.1111/os.12513
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to evaluate the effect of patellar denervation (PD) in preventing anterior knee pain (AKP) and improving knee function after total knee arthroplasty (TKA) without patellar resurfacing, and to help surgeons decide whether or not to use PD in TKA. METHODS:The electronic databas...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12815
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical outcomes of anterior and posterior instrumentation with different debridement and graft fusion methods for multi-level contiguous thoracic spinal tuberculosis. METHODS:We retrospectively evaluated 81 patients with multi-level contiguous thoracic spinal tuberculosis who underwent ante...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12288
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To investigate the methods for, and clinical outcome of, the operative treatment of thoracolumbar fractures through an approach via the paravertebral muscle (PVM). METHODS:From June 2005 to August 2006, 62 patients, comprising 48 men and 14 women with an average age of 45.2 years (range, 21-58) with thoracol...
journal_title:Orthopaedic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1757-7861.2009.00032.x
更新日期:2009-08-01 00:00:00
abstract::The authors describe a hybrid technique that involves a combination of open decompression and posterior lumbar interbody fusion (PLIF) and percutaneously inserted pedicle screws. This technique allows performance of PLIF and decompression via a midline incision and approach without compromising operative time and visu...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12042
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To investigate the efficiency of anterior decompression on the proximal-type cervical spondylotic amyotrophy patients. METHODS:This was a retrospective analysis. From January 2014 to November 2017, 21 patients with proximal-type cervical spondylotic amyotrophy (CSA) underwent anterior decompression. There we...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12654
更新日期:2020-06-01 00:00:00
abstract::To observe the morphology character of the anterior epidural space at the L4-5 disc level and to provide an anatomical basis for safely and accurately performing a percutaneous endoscopic lumbar discectomy (PELD). Fifty-five cases with L5 S1 lumbar disc herniation were included in this study, and cases with L4-5 disea...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12325
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To examine the results of an anular closure device for prevention of lumbar disc reherniation in daily routine practice. METHODS:Fifty patients with large anular defects were treated with limited discectomy and a bone-anchored anular closure device. The device physically occludes the defect in the anulus fib...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12495
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:To summarize the indications and the clinical effects of a transfibular neck osteotomy approach and a combined anterolateral and posterolateral approach in the treatment of fractures of the lateral tibial plateau involving the posterolateral column. METHODS:Eleven patients with lateral tibial plateau fractur...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12544
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To compare the biomechanical properties of single- and two-segment fusion for Denis type B spinal fracture. METHODS:Two female patients with Denis type B L1 vertebral fractures were studied. Both patients had achieved intervertebral fusion by 1 year postoperatively, at which time CT data were collected, incl...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12068
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:Relatively few studies have reported on the morphology of the supracondylar femur, which is a fundamental factor affecting prosthetic reconstruction. The objectives of the present study were to measure the morphological parameters of the supracondylar femur, to classify the supracondylar femur, and to provide...
journal_title:Orthopaedic surgery
pub_type: 杂志文章
doi:10.1111/os.12443
更新日期:2019-04-01 00:00:00