Association of Helicobacter pylori infection with metabolic syndrome in aged Chinese females.

abstract：:The topic of pheochromocytomas is becoming increasingly popular as a result of major advances in different medical fields, including laboratory diagnosis, genetics, therapy, and particularly in novel advances in imaging techniques. The present review article discusses current clinical, biochemical, genetic and histopa...

journal_title：Experimental and therapeutic medicine

authors： Čtvrtlík F,Koranda P,Schovánek J,Škarda J,Hartmann I,Tüdös Z

更新日期：2018-04-01 00:00:00

abstract：:Numerous studies have demonstrated that microRNAs (miRNAs) are dysregulated in esophageal squamous cell carcinoma (ESCC). Changes in miRNA expression may be associated with ESCC formation and progression. Therefore, the identification of ESCC-associated miRNAs may facilitate the development of effective therapeutic ap...

journal_title：Experimental and therapeutic medicine

authors： Zhen C,Huang J,Lu J

更新日期：2019-12-01 00:00:00

abstract：:Ovarian cancer is a highly prevalent cancer among women. Recent studies have indicated that microRNAs (miRs) may serve important roles in the pathogenesis of ovarian cancer. miR-519a was observed to be downregulated in tissue samples of patients with ovarian cancer; however, its role in ovarian cancer requires further...

journal_title：Experimental and therapeutic medicine

authors： Tian F,Jia L,Chu Z,Han H,Zhang Y,Cai J

更新日期：2018-02-01 00:00:00

abstract：:The DNA methylation inhibitor 5-aza-2'-deoxycytidine (5-aza-CdR) is widely used as an anticancer drug for the treatment of leukemia and solid tumors. Gastric cancer (GC) patients who were positive for caudal type homeobox transcription factor 2 (CDX2) expression showed a higher survival rate compared with those who we...

journal_title：Experimental and therapeutic medicine

authors： Zhang JF,Zhang JG,Kuai XL,Zhang H,Jiang W,Ding WF,Li ZL,Zhu HJ,Mao ZB

更新日期：2013-03-01 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a rare but highly aggressive type of malignancy. MicroRNA (miR)-25 has been demonstrated to be involved in the genesis of numerous cancer types. The aim of the present study was to investigate the prognostic value and functional role of miR-25 in CCA. The expression of miR-25 was determined...

journal_title：Experimental and therapeutic medicine

authors： Liu H,Ma L,Wang J

更新日期：2019-10-01 00:00:00

abstract：:The present study aimed to compare the clinical outcome of patients with coronary artery disease (CAD) who underwent a revascularization using conventional coronary angiography or a physiologically guided revascularization with Fractional Flow Reserve (FFR). Furthermore, outcomes in FFR guided percutaneous coronary in...

journal_title：Experimental and therapeutic medicine

authors： Baumann S,Mueller KSE,Hetjens S,Eder F,Schaefer AC,Becher T,Borggrefe M,Akin I,Loßnitzer D

更新日期：2019-03-01 00:00:00

abstract：:Sepsis is a serious condition characterized by an infectious process that induces a severe systemic inflammatory response. In this study, the effects of gemfibrozil (GFZ) on the inflammatory response associated with abdominal sepsis were investigated using a rat model of cecal-ligation and puncture (CLP). Male Wistar ...

journal_title：Experimental and therapeutic medicine

authors： Cámara-Lemarroy CR,Guzman-DE LA Garza FJ,Cordero-Perez P,Ibarra-Hernandez JM,Muñoz-Espinosa LE,Fernandez-Garza NE

更新日期：2015-03-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy and safety of polyethylene glycol 4000 (PEG 4000) for the treatment of constipation in children over 8 years of age. A total of 216 children from 7 hospitals were enrolled. A total of 105 patients received oral PEG 4000 (20 g/day) and 111 patients received oral lactul...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Wang B,Jiang X,Jiang M,Xu C,Shao C,Jia L,Huang Z,Xu X,Liu H,Shang L

更新日期：2012-05-01 00:00:00

abstract：:Dimethyl carbonate (DMC) is a widely used industrial chemical, which may be increasingly used in the future. However, its toxicity profile remains largely unknown. The present study was designed to investigate the effects of DMC exposure on the ovaries and the effect of autophagy activation on follicular development. ...

journal_title：Experimental and therapeutic medicine

authors： Tang Z,Zhang Z,Tang Y,Qi L,Yang F,Wang Z

更新日期：2017-12-01 00:00:00

abstract：:The ChrT gene encodes a chromate reductase enzyme which catalyzes the reduction of Cr(VI). The chromate reductase is also known as flavin mononucleotide (FMN) reductase (FMN_red). The aim of the present study was to clone the full-length ChrT DNA from Serratia sp. CQMUS2 and analyze the deduced amino acid sequence and...

journal_title：Experimental and therapeutic medicine

authors： Deng P,Tan X,Wu Y,Bai Q,Jia Y,Xiao H

更新日期：2015-03-01 00:00:00

abstract：:In the development of anti-blood cancer drugs, the chronic myelocytic leukemia (KU812), acute myelocytic leukemia (KG-1) and lymphoma (U937) cell lines are commonly used in preclinical pharmacology studies as human cancer xenograft models in mice. In the present study, mRNA expression levels of typical human ATP-bindi...

journal_title：Experimental and therapeutic medicine

authors： Takeuchi K,Shibata M,Kashiyama E,Umehara K

更新日期：2012-09-01 00:00:00

abstract：:The aim of the present study was to screen for biomarkers of Parkinson's disease (PD) using proteomics and bioinformatics approaches. PD patients were divided into three groups: Those without surgery (PD1 group); those who had undergone deep brain stimulation (DBS) surgery without electrode stimulation (PD2 group); an...

journal_title：Experimental and therapeutic medicine

authors： Dong W,Qiu C,Gong D,Jiang X,Liu W,Liu W,Zhang L,Zhang W

更新日期：2019-10-01 00:00:00

abstract：:This study aimed to investigate the reliability of ultrasound two-dimensional speckle tracking imaging (2D-STI) for the evaluation of myocardial ischemia in familial hypercholesterolemia (FH) patients. We recruited 28 patients clinically diagnosed with homozygous familial hypercholesterolemia (HoFH) and subjected them...

journal_title：Experimental and therapeutic medicine

authors： Song Y,Zhang RF,Liu Y

更新日期：2017-08-01 00:00:00

abstract：:Hepatic stellate cells (HSCs) have been demonstrated to have immunoinhibitory activity. The aim of this study was to investigate the role of HSCs in the development of immunotolerance following liver transplantation. A rat liver transplantation tolerance model [donor Lewis into recipient Dark Agouti (DA)] and rejectio...

journal_title：Experimental and therapeutic medicine

authors： Jiang Z,Chen Y,Feng X,Jiang J,Chen T,Xie H,Zhou L,Zheng S

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to investigate the anticarcinogenic effects of silymarin in diethylnitrosamine (DEN)-induced hepatocarcinogenic rat models. Severe and mild models of hepatocellular carcinoma (HCC) were generated by the intraperitoneal administration of 40 mg/kg DEN once a week for 18 weeks and 100 mg/kg DEN ...

journal_title：Experimental and therapeutic medicine

authors： Imamoto R,Okano JI,Sawada S,Fujise Y,Abe R,Murawaki Y

更新日期：2014-01-01 00:00:00

abstract：:The objective of this study was to investigate the effects of leukotriene B4 (LTB4) on the expression of interleukin-32 (IL-32) interferon-γ (IFN-γ) and chemokine monocyte chemoattractant protein (MCP-1) and macrophage inhibitory protein (MIP-1α) in rheumatoid arthritis (RA). The rat model of RA collagen induced-arthr...

journal_title：Experimental and therapeutic medicine

authors： Bi D,Bi D,Zhong M,Zhang H,Jin S,Ma S,Luo H

更新日期：2017-10-01 00:00:00

abstract：:Caspase-8 (encoded by the CASP-8 gene) is crucial in generating cell death signals and eliminating potentially malignant cells. Genetic variation in CASP8 may affect susceptibility to cancer. The CASP-8 -652 6N ins/del (rs3834129) polymorphism has been previously reported to influence the progression to several cancer...

journal_title：Experimental and therapeutic medicine

authors： Chen D,Ma T,Liu XW,Liu Z

更新日期：2012-10-01 00:00:00

abstract：:FRMD7 mutations are associated with X-linked idiopathic congenital nystagmus (ICN); however, the underlying mechanisms whereby mutations of FRMD7 lead to ICN remain unclear. In a previous study, the first FRMD7 splice variant (FRMD7-S) was cloned and identified, and FRMD7-S was hypothesized to play a significant role ...

journal_title：Experimental and therapeutic medicine

authors： Li Y,Pu J,Zhang B

更新日期：2014-10-01 00:00:00

abstract：:Discoid lateral meniscus of the knee causes a high morbidity in China. Since the traditional treatment to open the capsule and resect the meniscus often results in arthritis, it is now believed that a discoid lateral meniscus should be treated with arthroscopy to preserve part of the meniscus. The current study aimed ...

journal_title：Experimental and therapeutic medicine

authors： Cao H,Zhang Y,Qian W,Cheng XH,Ke Y,Guo XP

更新日期：2012-11-01 00:00:00

abstract：:The present report describes the clinical course and treatment of a Mooren-like ulcer associated with abuse of topical anesthetics and dexamethasone. A 38-year-old male physician treated himself with lidocaine, tetracaine and dexamethasone (DEX) eye drops for severe pain and decline of vision in both eyes. After six m...

journal_title：Experimental and therapeutic medicine

authors： Wu H,Hu Y,Shi XR,Xu F,Jiang CY,Huang R,Jia H

更新日期：2016-07-01 00:00:00

abstract：:Asthma is a major inflammatory airway disease with high incidence and mortality rates. The Global Initiative for Asthma released a report called 'The Global Burden of Asthma' in 2004. However, the specific pathogenesis of asthma remains unclear. An increasing number of studies have demonstrated that neuromedin U (NMU)...

journal_title：Experimental and therapeutic medicine

authors： Ren X,Dong F,Zhuang Y,Wang Y,Ma W

更新日期：2020-02-01 00:00:00

abstract：:The functions of telomeric repeat-binding factor 1 (TRF1) and 2 (TRF2) in oral carcinogenesis are largely unexplored. This study examined the relationship between the expression of TRF1 and TRF2 and clinicopathological variables and survival in oral cavity squamous cell carcinoma (OCSCC). Western blotting and immunohi...

journal_title：Experimental and therapeutic medicine

authors： Chuang HC,Chen CH,Huang CC,Fang FM,Tsai HT,Chien CY

更新日期：2011-01-01 00:00:00

abstract：:Tuberculosis is highly infectious and has a high incidence worldwide. Therefore, effective treatment is essential for the disease. The immune function and inflammatory factors can reflect the therapeutic effect of pulmonary tuberculosis to some extent. Thus, the aim of the present study was to investigate the clinical...

journal_title：Experimental and therapeutic medicine

authors： Cheng C,Pan W,Li X,Qu H

更新日期：2020-09-01 00:00:00

abstract：:Neuropathic pain (NP) is a common clinical chronic pain with very complex mechanisms. This study explored the function of activated Wnt signaling pathway in NP. A rat model of chronic constriction injury (CCI) was established. Different doses of IWP-2, a Wnt signal inhibitor, were intrathecally injected to observe the...

journal_title：Experimental and therapeutic medicine

authors： Zhao Y,Yang Z

更新日期：2018-10-01 00:00:00

abstract：:Scarred uterus is caused by cesarean section surgery, and this condition affects further gestation and delivery in patients. Previous evidence suggested that resveratrol, a polyphenol compound, presents beneficial outcomes for patients with scarred uterus. Therefore, the aim of the present study was to analyze the eff...

journal_title：Experimental and therapeutic medicine

authors： Ma H,Qiao Z

更新日期：2018-06-01 00:00:00

abstract：:The diagnostic value of detection of serum β-human chorionic gonadotropin (β-HCG) and Chlamydia trachomatis immunoglobulin G (CT-IgG) combined with transvaginal ultrasonography in early tubal pregnancy was investigated. A total of 55 patients with early tubal pregnancy were selected as the tubal pregnancy group, while...

journal_title：Experimental and therapeutic medicine

authors： Xin H,Liu W,Li P

更新日期：2018-07-01 00:00:00

abstract：:In spite of the favorable prognosis of early gastric cancer (EGC), recurrence or second primary cancers present in certain patients after curative surgery. It is crucial to identify who are at high risk and when. In the present study, 323 patients with EGC who underwent curative surgery were studied. A total of 22 pat...

journal_title：Experimental and therapeutic medicine

authors： Huang B,Wang Z,Xing C,Sun Z,Zhao B,Xu H

更新日期：2011-11-01 00:00:00

abstract：:Glucocorticoids are a class of steroid hormones commonly used for the treatment of hematological malignancies due to their ability to induce apoptosis in lymphoid cells. An understanding of the critical steps in glucocorticoid-induced apoptosis is required to identify sources of drug resistance. Previously, we found t...

journal_title：Experimental and therapeutic medicine

authors： Tome ME,Lee K,Jaramillo MC,Briehl MM

更新日期：2012-02-01 00:00:00

abstract：:The transient receptor potential melastatin 2 (TRPM2) channel, a Ca2+ permeable channel activated by cAMP, is expressed on pancreatic β-cells and is responsible for the regulation of insulin secretion. It is known that glucose-stimulated insulin secretion (GSIS) can be potentiated by glucagon like peptide-1 (GLP-1), a...

journal_title：Experimental and therapeutic medicine

authors： Pang B,Kim S,Li D,Ma Z,Sun B,Zhang X,Wu Z,Chen L

更新日期：2017-11-01 00:00:00

abstract：:The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene promoter and the h...

journal_title：Experimental and therapeutic medicine

authors： Yoruker EE,Mert U,Bugra D,Yamaner S,Dalay N

更新日期：2012-11-01 00:00:00