2D-STI combined with gated 99Tcm-MIBI MPI for the diagnosis of myocardial ischemia in hypercholesterolemia patients.

abstract：:Clinical efficacy of metoprolol combined with irbesartan and hydrochlorothiazide and non-invasive ventilator in the emergency treatment of patients with severe heart failure (HF) was investigated. A retrospective analysis of the medical records of 124 patients with severe HF admitted to Binzhou Medical University Hosp...

journal_title：Experimental and therapeutic medicine

authors： Zhang F,Zhou G,Guo L,Lu F,Zhou G

更新日期：2018-12-01 00:00:00

abstract：:Uterine leiomyoma is the most common benign tumor type of the female reproductive tract. Despite its high prevalence, the exact pathogenesis of the benign tumor remains unknown. In the present study, the effects of di-(2-ethylhexyl) phthalate (DEHP) on the proliferation and apoptosis rates and expression of inflammato...

journal_title：Experimental and therapeutic medicine

authors： Kim JH

更新日期：2018-06-01 00:00:00

abstract：:To suppress the invasion of hepatocellular carcinoma (HCC) cells into surrounding connective tissues during metastasis, we investigated the usefulness of sorafenib. In order to search for model cell lines, cell numbers were counted to reveal cell lines with the potential to proliferate in serum-free media. Cell prolif...

journal_title：Experimental and therapeutic medicine

authors： Tomizawa M,Shinozaki F,Sugiyama T,Yamamoto S,Sueishi M,Yoshida T

更新日期：2010-09-01 00:00:00

abstract：:Our study retrospectively investigated the expression of forkhead/winged helix transcription factor (Foxp3) in renal tissue and clinical features of patients with hepatitis B virus (HBV)-associated glomerulonephritis (HBV-GN). A total of 58 patients with HBV-GN were assigned to group A; 45 serum and renal tissue HBsAg...

journal_title：Experimental and therapeutic medicine

authors： Zhao W,Ma Y,Wang M,Shi C,Sun J,Chu K,Liu C

更新日期：2017-11-01 00:00:00

abstract：:The universal endocrine pathological state affecting young individuals and adults is type 2 diabetes mellitus, which has seen a significant increase in the last 30 years, particularly in children. Genetic and evnironmental factors are the causative agents for this pathological state in children. This rapid and wide sp...

journal_title：Experimental and therapeutic medicine

authors： Xue Y,Gao M,Gao Y

更新日期：2016-10-01 00:00:00

abstract：:The aim of the study was to detect the expression of interleukin-1β (IL-1β) in serum of patients with perimenopausal non-organic sleep disorder (PNSD) and to study the relationship between IL-1β and the severity of insomnia and liver depression, so as to benefit the prevention of PNSD. A total of 268 cases of perimeno...

journal_title：Experimental and therapeutic medicine

authors： Li H,Chen Y,Wu H,Huang J,Ma K,Zheng J,Lv S

更新日期：2019-01-01 00:00:00

abstract：:Pediatric patients with systemic-onset juvenile idiopathic arthritis (SOJIA) may be treated with tacrolimus. However, the therapeutic range for tacrolimus is narrow with considerable inter- and intra-individual variability, making it difficult to formulate an ideal dosage regimen for personalized treatment. The purpos...

journal_title：Experimental and therapeutic medicine

authors： Wang D,Chen X,Xu H,Li Z

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to investigate the pathogenesis of autophagy and apoptosis mediated by Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signal pathway after the onset of acute spinal cord injury (ASCI). A total of 45 Sprague-Dawley adult rats of either sex were selected for this...

journal_title：Experimental and therapeutic medicine

authors： Xia Y,Xia H,Chen D,Liao Z,Yan Y

更新日期：2017-08-01 00:00:00

abstract：:The aim of the present study was to evaluate the thymuses of non-thymomatous myasthenia gravis (MG) patients by computed tomography (CT) for differentiating lymphoid follicular hyperplasia (LFH) thymus from normal/involuted thymus in order to assist surgeons in determining whether a non-thymomatous MG patient requires...

journal_title：Experimental and therapeutic medicine

authors： Zhang H,Zhang P,Yu TL

更新日期：2019-01-01 00:00:00

abstract：:Chronic myelogenous leukemia (CML) is a condition characterized by a balanced genetic translocation, t (9;22) (q34;q11.2), which leads to a fusion of the Abelson oncogene (ABL) from chromosome 9q34 with the breakpoint cluster region (BCR) gene on chromosome 22q11.2. This rearrangement is referred to as the Philadelphi...

journal_title：Experimental and therapeutic medicine

authors： Shen X,Zhang M,Shen Y,Shi W,Liu W,Wei WU

更新日期：2015-10-01 00:00:00

abstract：:Numerous studies have demonstrated that neuronal cell death occurs via extrinsic (death receptors) and intrinsic (mitochondria) pathways. Radiation induces caspase activation fundamentally via the mitochondrial pathway. To investigate the role of caspase, a cell permeable pan-caspase inhibitor, z-VAD-fmk [N-benzyloxyc...

journal_title：Experimental and therapeutic medicine

authors： Li J,Wang Y,DU L,Xu C,Cao J,Wang Q,Liu Q,Fan F

更新日期：2014-02-01 00:00:00

abstract：:Electrospinning using biocompatible polymer scaffolds, seeded with or without stem cells, is considered a promising technique for producing fibrous scaffolds with therapeutic possibilities for ischemic heart disease. However, no optimal scaffolds for treating ischemic heart disease have been identified thus far. In th...

journal_title：Experimental and therapeutic medicine

authors： Du M,Gu J,Wang J,Xue Y,Ma Y,Mo X,Xue S

更新日期：2019-05-01 00:00:00

abstract：:Opioids are commonly used in cancer pain management. The present study aimed to investigate the occurrence of endocrine dysfunction in patients with cancer pain treated with opioids. The study included 20 patients with cancer-associated pain. All data were obtained from malignant tumors diagnosed and followed up at th...

journal_title：Experimental and therapeutic medicine

authors： Merdin A,Merdin FA,Gündüz Ş,Bozcuk H,Coşkun HŞ

更新日期：2016-05-01 00:00:00

abstract：:The aim of this study was to explore the chronergy of intravenous recombinant streptokinase (r-SK) in patients with acute myocardial infarction (AMI). A total of 114 patients were divided into two groups according to the time of AMI onset: the morning onset (6:01-12:00, n=53) and non-morning onset (12:01-06:00, n=61) ...

journal_title：Experimental and therapeutic medicine

authors： Wang ZM,Liu YB,Jin QC,Wang XQ,Dai M,Shao H,Zhao WP,Dong QL,Wang SP,Zhang HT,Kong LC,Liu SY,Wang DY

更新日期：2013-05-01 00:00:00

abstract：:The present study aims to raise awareness about the necessity of a thorough differential diagnosis process when diagnosing paraganglioma as it is an extremely rare entity with a high malignant potential. A 64-year-old female patient was admitted to the hospital with symptoms of bowel obstruction and a palpable abdomin...

journal_title：Experimental and therapeutic medicine

authors： Iliesiu A,Ungureanu IA,Petca A,Constantin MM,Petca RC,Sandru F,Constantin T,Dumitrascu MC

更新日期：2020-09-01 00:00:00

abstract：:The aim of this study was to investigate the anticarcinogenic effects of silymarin in diethylnitrosamine (DEN)-induced hepatocarcinogenic rat models. Severe and mild models of hepatocellular carcinoma (HCC) were generated by the intraperitoneal administration of 40 mg/kg DEN once a week for 18 weeks and 100 mg/kg DEN ...

journal_title：Experimental and therapeutic medicine

authors： Imamoto R,Okano JI,Sawada S,Fujise Y,Abe R,Murawaki Y

更新日期：2014-01-01 00:00:00

abstract：:The present study aimed to investigate the effect of triptolide (TL) on ulcerative colitis (UC) and explore the potential association between the therapeutic effects of TL and IL-1β expression using a 4,4-dimethyl-4-silapentane-1-sulfonic acid (DSS)-induced mouse model to simulate human UC. A total of 70 BALB/c female...

journal_title：Experimental and therapeutic medicine

authors： Zhang H,Gong C,Qu L,Ding X,Cao W,Chen H,Zhang B,Zhou G

更新日期：2016-09-01 00:00:00

abstract：:Metastatic breast cancer is one of the most common metastatic tumors. Although studies have validated the role of β-inducible gene-h3 (βig-h3) in human biology and disease, the detailed mechanisms mediated by βig-h3 in breast carcinoma metastasis remain unclear. Thus, the present study investigated the role and potent...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,Li Z

更新日期：2018-03-01 00:00:00

abstract：:NY-ESO-1 has been identified as one of the most immunogenic antigens; thus, is a highly attractive target for cancer immunotherapy. The present study analyzed the expression of serum antibodies (Abs) against NY-ESO-1 in patients with advanced colorectal cancer (CRC), with the aim of guiding the treatment of NY-ESO-1-b...

journal_title：Experimental and therapeutic medicine

authors： Long YY,Wang Y,Huang QR,Zheng GS,Jiao SC

更新日期：2014-10-01 00:00:00

abstract：:This study aimed to investigate the effect of ambroxol on the concentration of cefotaxime in the bronchioalveolar lavage fluid of rats with bleomycin-induced pulmonary fibrosis. A total of 54 Wistar male rats were randomly divided into three groups, namely the normal control group, model group and ambroxol group. On e...

journal_title：Experimental and therapeutic medicine

authors： Chen F,Zhang YX,Zhang CQ

更新日期：2015-02-01 00:00:00

abstract：:In the present study, the thenar muscles were evaluated using magnetic resonance imaging (MRI), in addition, the correlations between thenar muscle changes, clinical findings and electrodiagnostic results from patients with carpal tunnel syndrome were investigated. The subjects were 13 patients (17 wrists) who were cl...

journal_title：Experimental and therapeutic medicine

authors： Dilokhuttakarn T,Naito K,Kinoshita M,Sugiyama Y,Goto K,Iwase Y,Kaneko K

更新日期：2017-09-01 00:00:00

abstract：:Recurrent patellar dislocations were treated via knee arthroscopy combined with C-arm fluoroscopy, and reconstruction of the medial patellofemoral ligaments. Between October 2013 and March 2017, 52 cases of recurrent patellar dislocation [27 males and 25 females; age, 16-47 years (mean, 21.90 years)] were treated. Art...

journal_title：Experimental and therapeutic medicine

authors： Li L,Wang H,He Y,Si Y,Zhou H,Wang X

更新日期：2018-06-01 00:00:00

abstract：:Psoriasis affects 2-4% of the population worldwide and its treatment is currently far from satisfactory. Calcipotriol and Portulaca oleracea have been reported to exhibit the capacity to inhibit inflammation in psoriatic patients and improve their clinical condition. However, the efficacy of a combination regimen of t...

journal_title：Experimental and therapeutic medicine

authors： Zhao H,Li S,Luo F,Tan Q,Li H,Zhou W

更新日期：2015-02-01 00:00:00

abstract：:The aim of this study was to isolate and purify Rhizoma Pinelliae trypsin inhibitor (RPTI), determine its N-terminal amino acid sequence and evaluate its inhibitory effect on the proliferation of poorly differentiated BGC-823 human gastric adenocarcinoma cells. RPTI was separated and purified from a 40% (NH4)2SO4 prec...

journal_title：Experimental and therapeutic medicine

authors： Zu G,Wang H,Wang J,Dou Y,Zhao W,Sun Y

更新日期：2014-07-01 00:00:00

abstract：:Active P-glycoprotein (P-gp) molecules have been shown to transport steroids out of peripheral lymphocytes, resulting in poor responses to systemic steroid therapy in patients with systemic lupus erythematosus (SLE). This study was carried out to investigate the correlation between the expression or activity of P-gp i...

journal_title：Experimental and therapeutic medicine

authors： Zhang B,Shi Y,Lei TC

更新日期：2012-10-01 00:00:00

abstract：:The diaphragm is an important respiratory organ. The aim of this study was to quantitatively evaluate the longitudinal deformation of the right hemidiaphragm in normal subjects using two-dimensional strain ultrasound speckle tracking. Twenty-one healthy subjects were enrolled in this study. GE Healthcare Vivid E9 equi...

journal_title：Experimental and therapeutic medicine

authors： Ye X,Xiao H,Bai W,Liang Y,Chen M,Zhang S

更新日期：2013-08-01 00:00:00

abstract：:Erythropoietin (EPO), a glycoprotein originally known for its important role in the stimulation of erythropoiesis, has recently been shown to have significant protective effects in animal models of kidney and intestinal ischemia-reperfusion injury (IRI). However, the mechanism underlying these protective effects remai...

journal_title：Experimental and therapeutic medicine

authors： Rong R,Xijun X

更新日期：2015-08-01 00:00:00

abstract：:The aim of the present study was to investigate the effect of Forkhead family transcription factor P3 (Foxp3) knockdown on the function of cluster of differentiation (CD)4+CD25+ regulatory T cell (Tregs) and the tumor growth of a hepatocellular carcinoma (HCC) mouse model. CD4+CD25+ Tregs and CD4+CD25- T cells were so...

journal_title：Experimental and therapeutic medicine

authors： Shi C,Zhang Y,Yang H,Dong T,Chen Y,Xu Y,Yang X,Liu P

更新日期：2018-01-01 00:00:00

abstract：:Fluvoxamine, a common antidepressant agent, is designed to exert its pharmacological effect by inhibiting synaptic serotonin reuptake. However, increasing evidence has demonstrated that σ1 receptors are likely to be involved in the mechanism of action of fluvoxamine. The present study aimed to observe the effects of f...

journal_title：Experimental and therapeutic medicine

authors： Su DA,Jiang RY,Liu N,Ding LC,Wang DM,Yu HY,Yan ES,Zhu MH,Zhu B

更新日期：2014-02-01 00:00:00

abstract：:To study the effects of multiple cerebral concussion (MCC)-induced chronic traumatic encephalopathy on balance motion behavior learning and memory abilities of rats and its possible mechanism. 4MCC rat models were established by means of striking the head (4MCC group, n=15), while normal Sprague-Dawley (SD) rats were ...

journal_title：Experimental and therapeutic medicine

authors： Zhang H,Zhang Z,Wang Z,Zhen Y,Yu J,Song H

更新日期：2018-09-01 00:00:00