Spike-Wave Discharges and Sleep-Wake States during Circadian Desynchronization: No Effects of Agomelatine upon Re-Entrainment.

abstract：:Androgens are known to affect cognitive and mnemonic aspects of spatial processing. The cholinergic system is thought to play an important role in cognition and memory, but little is known about the interaction between androgen and cholinergic neurons. The present study focused on the effects of testosterone on the ch...

journal_title：Neuroscience

authors： Nakamura N,Fujita H,Kawata M

更新日期：2002-01-01 00:00:00

abstract：:In situ hybridization was used to measure the levels of proenkephalin mRNA and prodynorphin mRNA in regions of rat striatum and nucleus accumbens. Chronic administration of haloperidol (2.4 mg/kg/day for 7 days) increased the levels of proenkephalin mRNA in both striatum and nucleus accumbens. In contrast, the levels ...

journal_title：Neuroscience

authors： Morris BJ,Höllt V,Herz A

更新日期：1988-05-01 00:00:00

abstract：:The neuropeptide oxytocin (OT) has been implicated in a range of mammalian reproductive and social behaviors including parent-offspring bonding and partner preference formation between socially monogamous mates. Its role in mediating non-reproductive social relationships in rodents, however, remains largely unexplored...

journal_title：Neuroscience

authors： Beery AK,Zucker I

更新日期：2010-08-25 00:00:00

abstract：:Perceiving the sensory consequences of our actions with a delay alters the interpretation of these afferent signals and impacts motor learning. For reaching movements, delayed visual feedback of hand position reduces the rate and extent of visuomotor adaptation, but substantial adaptation still occurs. Moreover, the d...

journal_title：Neuroscience

authors： Shiller DM,Mitsuya T,Max L

更新日期：2020-10-15 00:00:00

abstract：:The caudal anterior cingulate cortex (cAC) is an essential component of the circuitry involved in acquisition of forebrain-dependent trace eyeblink conditioning. Lesions of the cAC prevent trace eyeblink conditioning [Weible AP, McEchron MD, Disterhoft JF (2000) Cortical involvement in acquisition and extinction of tr...

journal_title：Neuroscience

authors： Weible AP,Weiss C,Disterhoft JF

更新日期：2007-03-02 00:00:00

abstract：:The central nervous system responds to diverse neurologic injuries with a vigorous activation of astrocytes. While this phenomenon is found in many different species, its function is obscure. Understanding the molecular profile characteristic of reactive astrocytes should help define their function. The purpose of thi...

journal_title：Neuroscience

authors： Eddleston M,Mucke L

更新日期：1993-05-01 00:00:00

abstract：:Morphine (opiate agonist) produced a dose-dependent decrease in the spontaneous motility of 5- and 9-day chick embryos. Naloxone (opiate antagonist) appeared to reverse competitively the inhibition of motility caused by morphine. The effects of morphine on spontaneous motility in 5-day embryos were also reversed stere...

journal_title：Neuroscience

authors： Maderdrut JL,Reitzel JL,Okado N,Oppenheim RW

更新日期：1985-10-01 00:00:00

abstract：:Decreased levels of soluble ubiquitin carboxy-terminal hydrolase L1 (UCHL1) have been reported in the brains of sporadic Alzheimer's disease (AD) patients, and the introduction of UCHL1 rescued the synaptic and cognitive function of AD model mice. Obviously, a reduction in the levels of UCHL1 may play a role in the pa...

journal_title：Neuroscience

authors： Zhao ZB,Wu L,Xiong R,Wang LL,Zhang B,Wang C,Li H,Liang L,Chen SD

更新日期：2014-09-05 00:00:00

abstract：:After loading cultured rat hippocampal neurons with teh acetoxymethyl ester of the Ca2+ buffer BAPTA, or its dimethyl analogue DMB, the magnitudes of transient (20-25 s) depolarization- or excitatory amino acid-induced Ca2+ responses were reduced, as were the rates of increase and recovery of [Ca2+]i. In contrast, dur...

journal_title：Neuroscience

authors： Abdel-Hamid KM,Baimbridge KG

更新日期：1997-12-01 00:00:00

abstract：:Repeated administration of amphetamine-like psychostimulants produce a progressive and long-lasting hypersensitivity to their behavioural effects known as behavioural sensitization. Previous studies have shown that administration of the purinergic P2 receptor agonist 2-methylthio ATP into the nucleus accumbens of rats...

journal_title：Neuroscience

authors： Kittner H,Krügel U,Illes P

更新日期：2001-01-01 00:00:00

abstract：:Endomorphin 2 (EM2) plays essential roles in regulating nociceptive transmission within the spinal dorsal horn, where EM2-immunopositive (EM2-IP) fibers and terminals are densely encountered. However, the origins of these EM2-IP structures are still obscure. Unilateral primary sensory afferents disruption (lumbar 3-6 ...

journal_title：Neuroscience

authors： Hui R,Wang W,Chen T,Lü BC,Li H,Zhang T,Wu SX,Li YQ

更新日期：2010-08-11 00:00:00

abstract：:Developmental or degenerative damage of the neuronal architecture in the entorhinal cortex may disintegrate a functional part of hippocampal input since the entorhinal cortex provides a major source of neocortical and subcortical input to the hippocampus. These alterations, such as seen in Alzheimer's disease, schizop...

journal_title：Neuroscience

authors： Falkenberg T,Metsis M,Timmusk T,Lindefors N

更新日期：1993-12-01 00:00:00

abstract：:Previous studies found that prostaglandins in skeletal muscle play a role in evoking the exercise pressor reflex; however the role played by prostaglandins in the spinal transmission of the reflex is not known. We determined, therefore, whether or not spinal blockade of cyclooxygenase (COX) activity and/or spinal bloc...

journal_title：Neuroscience

authors： Stone AJ,Copp SW,Kaufman MP

更新日期：2014-09-26 00:00:00

abstract：:Musculoskeletal pain conditions, particularly those associated with temporomandibular disorders (TMD) affect a large percentage of the population. Identifying mechanisms underlying hyperalgesia could contribute to the development of new treatment strategies for the management of TMD and other muscle pain conditions. I...

journal_title：Neuroscience

authors： Saloman JL,Chung MK,Ro JY

更新日期：2013-03-01 00:00:00

abstract：:The hippocampal CA1 region receives cortical information via two main inputs: directly via the perforant (temporoammonic) path (pp-CA1 synapse) and indirectly via the tri-synaptic pathway. Although synaptic plasticity has been reported at the pp-CA1 synapse of freely behaving animals, the mechanisms underlying this ph...

journal_title：Neuroscience

authors： Aksoy-Aksel A,Manahan-Vaughan D

更新日期：2015-11-19 00:00:00

abstract：:The distribution of D1 dopamine receptors was studied autoradiographically in the basal ganglia of the cat, monkey and human. These receptor binding sites were labeled directly with the D1-selective antagonist [3H]SCH 23390, and ligand-binding assays were performed concurrently. Serial- or same-action analysis permitt...

journal_title：Neuroscience

authors： Besson MJ,Graybiel AM,Nastuk MA

更新日期：1988-07-01 00:00:00

abstract：:Most patients with temporal lobe epilepsy (TLE), the most common type of epilepsy, show pronounced loss of neurons in limbic brain regions, including the hippocampus. The massive neurodegeneration in the hippocampus is known as hippocampal sclerosis, and is considered one of the hallmarks of this type of difficult-to-...

journal_title：Neuroscience

authors： Brandt C,Potschka H,Löscher W,Ebert U

更新日期：2003-01-01 00:00:00

abstract：:Serotonin (5-HT) and norepinephrine (NE) have been implicated in the mediation of endogenous analgesic mechanisms via the descending inhibitory pain pathway in the brain, and dysfunction in both the 5-HT and NE systems has been suggested as an etiology of fibromyalgia (FM). Given that 5-HT reuptake inhibition in the b...

journal_title：Neuroscience

authors： Murai N,Fushiki H,Honda S,Murakami Y,Iwashita A,Irie M,Tamura S,Nagakura Y,Aoki T

更新日期：2015-03-19 00:00:00

abstract：:Neurons in the region of dorsomedial hypothalamus are involved in the organization of the physiological responses to emotional stress. We have recently shown that the cardiovascular response evoked by activation of dorsomedial hypothalamus neurons is largely dependent on a synaptic relay with the lateral/dorsolateral ...

journal_title：Neuroscience

authors： da Silva LG Jr,Menezes RC,Villela DC,Fontes MA

更新日期：2006-01-01 00:00:00

abstract：:Depolarization-induced transmitter release in synaptosomes prepared from the hippocampus of aged rats is decreased compared with release from young animals. Although the underlying cause of this deficit is not known, some evidence suggests that increased membrane rigidity may contribute to these age-related synaptic c...

journal_title：Neuroscience

authors： McGahon BM,Martin DS,Horrobin DF,Lynch MA

更新日期：1999-01-01 00:00:00

abstract：:The hypothalamic-pituitary-adrenal (HPA) axis underlies both adaptive and maladaptive responses to stress and may be an important marker of childhood vulnerability to psychopathology, although little is known about genetic variants that influence cortisol reactivity. We therefore examined associations between corticot...

journal_title：Neuroscience

authors： Sheikh HI,Kryski KR,Smith HJ,Hayden EP,Singh SM

更新日期：2013-01-15 00:00:00

abstract：:The circadian rhythms of mammals are generated by the circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Its intrinsic period is entrained to a 24 h cycle by external cues, mainly by light. Light impinging on the SCN at night causes either advancing or delaying phase shifts of the circad...

journal_title：Neuroscience

authors： Bendová Z,Sumová A,Mikkelsen JD

更新日期：2009-03-17 00:00:00

abstract：:Recent studies have demonstrated that astrocytes express a variety of ion channels and neurotransmitter receptors and can modulate the activity of neurons. Since a single astrocyte makes tight contacts with many neighboring neuronal cells, they can provide efficient and wide modulation of neuronal networks. Here, we p...

journal_title：Neuroscience

authors： Yamazaki Y,Hozumi Y,Kaneko K,Li J,Fujii S,Miyakawa H,Kudo Y,Kato H

更新日期：2005-01-01 00:00:00

abstract：:GABA release was recorded in vivo by push-pull perfusion from the globus pallidus and substantia nigra of control rats, rats with unilateral ibotenic acid lesions of the neostriatum, and rats with embryonic striatal tissue grafts implanted in the lesioned striatum. The lesions reduced baseline levels of GABA release t...

journal_title：Neuroscience

authors： Sirinathsinghji DJ,Dunnett SB,Isacson O,Clarke DJ,Kendrick K,Björklund A

更新日期：1988-03-01 00:00:00

abstract：:Fetal alcohol spectrum disorder is associated with defects in neuronal generation, migration, and differentiation. The present study tested the hypothesis that ethanol exposure during the period of naturally occurring neuronal death causes a time- and Bax-dependent neuronal loss. Wild-type and Bax knockout mice were g...

journal_title：Neuroscience

authors： Britton SM,Miller MW

更新日期：2018-01-15 00:00:00

abstract：:The glucocorticoid-induced receptor (GIR) is an orphan G-protein-coupled receptor awaiting pharmacological characterization. GIR was originally identified in murine thymoma cells, and shows a widespread, yet not completely complementary distribution in mouse and human brain. Expression of the mouse GIR gene is modulat...

journal_title：Neuroscience

authors： Sah R,Pritchard LM,Richtand NM,Ahlbrand R,Eaton K,Sallee FR,Herman JP

更新日期：2005-01-01 00:00:00

abstract：:Pathological narcissism is often characterized by arrogant behavior, a lack of empathy, and willingness to exploit other individuals. Generally, individuals with high levels of narcissism are more likely to suffer mental disorders. However, the brain structural basis of individual pathological narcissism trait among h...

journal_title：Neuroscience

authors： Mao Y,Sang N,Wang Y,Hou X,Huang H,Wei D,Zhang J,Qiu J

更新日期：2016-07-22 00:00:00

abstract：:The proto-oncogene bcl-2 and its family members, bcl-x and bax are recognized as major regulators of cell death and survival. Although Bcl-2 and Bcl-x are expressed in brain, little is known how they are regulated in neurons. Here we have studied the expression of bcl-2, bcl-xL and bax mRNA in rat cerebellar granule n...

journal_title：Neuroscience

authors： Ohga Y,Zirrgiebel U,Hamnér S,Michaelidis TM,Cooper J,Thoenen H,Lindholm D

更新日期：1996-08-01 00:00:00

abstract：:A previous study in our laboratory, involving early stage, amyloid pathology in 8-month-old transgenic mice, demonstrated a selective loss of cholinergic terminals in the cerebral and hippocampal cortices of doubly transgenic (APP(K670N,M671L)+PSl(M146L)) mice, an up-regulation in the single mutant APP(K670N,M671L) mi...

journal_title：Neuroscience

authors： Hu L,Wong TP,Côté SL,Bell KF,Cuello AC

更新日期：2003-01-01 00:00:00

abstract：:Conduction time is typically ignored in computational models of neural network function. Here we consider the effects of conduction delays on the synchrony of neuronal activity and neural oscillators, and evaluate the consequences of allowing conduction velocity (CV) to be regulated adaptively. We propose that CV vari...

journal_title：Neuroscience

authors： Pajevic S,Basser PJ,Fields RD

更新日期：2014-09-12 00:00:00