Abstract:
:Immunoreactive TRH-containing neurons and their synaptic associations were studied electron microscopically in the paraventricular nucleus (PVN) and dorsomedial nucleus (DMH) of the rat hypothalamus. In propylthiouracil (PTU)-treated rats, the immunoreactive cell bodies in the PVN appeared to be activated, showing a hypertrophic perikaryon, well developed Golgi bodies and numerous secretory granules. No such alterations were evident in the TRH neurons in the DMH. These findings suggest that the PVN-TRH neurons are involved in the hypothalamic-hypophysial-thyroid axis. Further, it was shown that unlabeled nerve terminals containing small and large clear vesicles make synaptic contacts with the TRH perikarya in the PVN. Thus it is likely that PVN-TRH neurons are regulated both by thyroid hormones and by other neuronal signals. In the DMH, unlabeled nerve terminals containing small and large clear vesicles, and immunoreactive terminals form synapses with TRH neurons. Thus the DMH-TRH neurons may be under dual neuronal control. It was further noted that in the DMH and PVN, TRH nerve terminals make synaptic contacts with other unlabeled neurons. It is evident that TRH acts as a neurotransmitter or neuromodulator, although the origin of TRH terminals should be elucidated.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Hisano S,Ishizuka H,Nishiyama T,Tsuruo Y,Katoh S,Daikoku Sdoi
10.1007/BF00237473subject
Has Abstractpub_date
1986-01-01 00:00:00pages
495-504issue
3eissn
0014-4819issn
1432-1106journal_volume
63pub_type
杂志文章abstract::Quantitative in situ hybridization was used to examine the expression of mRNA for nerve growth factor (NGF) and its receptors, p140Trk (TrkA) and p75LNGFR (LNGFR), in different brain regions of adult (3-month-old) and aged (27-month-old) Wistar rats. The brain regions studied were hippocampus (dentate gyrus, CA3 regio...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005629
更新日期:1997-04-01 00:00:00
abstract::This paper presents ILGM (the Infant Learning to Grasp Model), the first computational model of infant grasp learning that is constrained by the infant motor development literature. By grasp learning we mean learning how to make motor plans in response to sensory stimuli such that open-loop execution of the plan leads...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-1914-1
更新日期:2004-10-01 00:00:00
abstract::Correlations between pairs of spontaneous climbing fiber responses (CFRs) recorded from couples of nearby Purkinje cells (PCs) were studied in immature rats by using cross-correlograms between CFR pairs, and compaired to those in adult animals. Correlations were found as early as day 3. Some days later, on PN days 7--...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236821
更新日期:1979-01-01 00:00:00
abstract::The European Resuscitation Guidelines recommend that survivors of cardiac arrest (CA) be resuscitated with 100% O2 and undergo subsequent-post-return of spontaneous circulation (ROSC)-reduction of O2 supply to prevent hyperoxia. Hyperoxia produces a "second neurotoxic hit," which, together with the initial ischemic in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05746-6
更新日期:2020-04-01 00:00:00
abstract::Reactive responses to balance perturbations have been shown to be improved by training. This investigation aimed to compare the effects of block and random training perturbation schedules on stability gains of compensatory arm and leg movements in response to unpredictable large-magnitude balance perturbations. Pertur...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05806-x
更新日期:2020-05-01 00:00:00
abstract::This study compared and contrasted the manifestation of neuropathic pain behaviors in several strains of rats. These included ACI, Brown-Norway, Fischer 344, Lewis, Long-Evans, Sprague-Dawley, and Wistar-Furth, all obtained from Harlan Sprague-Dawley Inc. Comparison was also made between two substrains of Sprague-Dawl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050886
更新日期:1999-11-01 00:00:00
abstract::In order to see whether septal neurones are connected to the hypothalamic neurones secreting vasopressin or oxytocin, neurones in different regions of the septum were recorded during electrical stimulation of the supraoptic nucleus. The position of the stimulating electrode within the latter was verified using lactati...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237493
更新日期:1981-01-01 00:00:00
abstract::Stimulation of the parietal association cortex as well as the frontal motor cortex elicited clearly extracellular unitary activities or field potentials in the ipsilateral inferior olive in the cat. The parietal-induced responses came out generally at a longer and more variable latency than the frontal-induced ones. T...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF01474258
更新日期:1979-09-01 00:00:00
abstract::Although maintenance of steady contractions is required for many daily tasks, there is little understanding of brain areas that modulate lower limb force accuracy. Functional magnetic resonance imaging was used to determine brain areas associated with steadiness and force during static (isometric) lower limb target-ma...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3976-z
更新日期:2014-10-01 00:00:00
abstract::We examine cross-modality commonalities in visual and auditory imageries during fMRI scanning in a sample of healthy young adults. In a visual task combining viewed and imagined stimuli, 28 participants were asked to imagine novel scenes related to the other images, and in a similar auditory task combining heard and i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-019-05492-4
更新日期:2019-05-01 00:00:00
abstract::The present study was carried out to determine the effects of central nervous free fatty acids, lysophospholipids, or platelet activating factor (PAF), in a mouse facial carrageenan injection model of orofacial pain. Mice that received intracerebroventricular (I.C.V.) injection of arachidonic acid or oleic acid showed...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0672-7
更新日期:2006-10-01 00:00:00
abstract::Changing direction during walking is a common task humans encounter every day. This destabilizing event requires the central nervous system (CNS) to quickly produce an appropriate response, maintain stability, and propel the body in the intended direction. Previous research has demonstrated that 'individuals with mult...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3873-5
更新日期:2014-06-01 00:00:00
abstract::The present study was conducted to visualize the ultrastructural features of vestibular efferent boutons in the oyster toadfish, Opsanus tau. The crista ampullaris of the horizontal semicircular canal was processed for and examined by routine transmission electron microscopy. The results demonstrate that such boutons ...
journal_title:Experimental brain research
pub_type: 更正并重新发布的文章,杂志文章
doi:10.1007/s00221-004-1898-x
更新日期:2004-07-01 00:00:00
abstract::Here, we demonstrate a systematic shift in the perceived location of a tactile stimulus on the arm toward where the eye is looking. Participants reported the perceived position of touches presented between the elbow and the wrist while maintaining eye positions at various eccentricities. The perceived location of the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1884-4
更新日期:2009-09-01 00:00:00
abstract::Extracellular single-unit recordings were made during day- and night-time in the pineal gland of urethane-anesthetized adult male Sprague-Dawley rats. All cells exhibiting spontaneous electrical activity had firing frequencies from less than 1 Hz to about 100 Hz, and their discharge patterns were characterized as regu...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235276
更新日期:1984-01-01 00:00:00
abstract::Extracellular recordings of neuronal activity made in the lumbosacral spinal segments of the anesthetized cat have disclosed the existence of a set of neurons in Rexed's laminae III-VI that discharged in a highly synchronized manner during the occurrence of spontaneous negative cord dorsum potentials (nCDPs) and respo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1303-6
更新日期:2003-02-01 00:00:00
abstract::The arm movement control system often relies on visual feedback to drive motor adaptation and to help specify desired trajectories. Here we studied whether kinematic errors that were indicated with auditory feedback could be used to control reaching in a way comparable with when vision was available. We randomized twe...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-012-3144-2
更新日期:2012-08-01 00:00:00
abstract::When asked to identify the position of a sound, listeners can report its perceived location as well as their subjective certainty about this spatial judgement. Yet, research to date focused primarily on measures of perceived location (e.g., accuracy and precision of pointing responses), neglecting instead the phenomen...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05748-4
更新日期:2020-03-01 00:00:00
abstract::The projection from the nucleus prepositus hypoglossi (PH) to the superior colliculus (SC) has been proposed to provide a feedback control of collicular saccadic activities. The present study aimed to identify the functional properties of PH neurones projecting to the SC relative to eye movement parameters. Preposito-...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229141
更新日期:1996-08-01 00:00:00
abstract::In the lateral septal area (LSA), both inhibitory and excitatory dopamine (DA) actions, as well as hypothalamic and midbrain DA efferents, have been described. Some neurons of the hypothalamic and midbrain DA systems contain somatostatin (SOM) or neurotensin (NT), and, in the LSA, the distribution of fibers containing...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229030
更新日期:1993-01-01 00:00:00
abstract::The study aimed to compare the ability of dance and non-dance subjects to perform fine control of a simple heel-raising/lowering movement, and to determine if there are any differences in motor unit activity in the primary plantar flexor muscles during the movement. Subjects were instructed to accurately track a sinus...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5131-0
更新日期:2018-02-01 00:00:00
abstract::Abstract. Although the contribution of binocular vision to reach-to-grasp movements has been extensively studied, it has been largely ignored in locomotion. The aim of these studies was to explore the role of binocular vision during the approach phase and step over the obstacle and the contribution of head movements t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-001-0948-x
更新日期:2002-02-01 00:00:00
abstract::Emotional processing that occurs partially in advance of perceptual processing is known as pre-perceptual emotional processing. The facilitation of sensory processing due to pre-perceptual emotional processing can be observed in visual search and attentional blink tasks. However, previous event-related potential studi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4486-3
更新日期:2016-02-01 00:00:00
abstract::The spatial separation of the eyes in animals with overlapping visual fields means that parts of a three dimensional object project to slightly disparate retinal points in each eye. This disparity, once interpreted by the brain, is thought to be a sufficient condition for stereoperception. In the present experiment, s...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239515
更新日期:1986-01-01 00:00:00
abstract::The present study investigated age-related changes in the attentional demands associated with interlimb coordination involving upper and lower limbs performed at three different movement frequencies. Younger and older adults performed rhythmical, 180° out-of-phase flexion-extension movements of the knee and elbow with...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3511-7
更新日期:2013-06-01 00:00:00
abstract::The content of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) in motoneurons was studied in four motor pools supplying muscles in the rat hind limb subserving different types of motor activity. The motor pools were identified by retrograde labeling with horseradish peroxidase or fluorophore-conjugated...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227109
更新日期:1993-01-01 00:00:00
abstract::The objective of this study was to define cortical and subcortical structures activated during both active and passive movements of the ankle, which have a fundamental role in the physiology of locomotion, to improve our understanding of brain sensorimotor integration. Sixteen healthy subjects, all right-foot dominant...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2335-5
更新日期:2005-09-01 00:00:00
abstract::The blood-brain barrier (BBB) arises from epithelial-like tight junctions that virtually cement adjoining capillary endothelium together in the brain microvasculature. Several experimental manipulations have been shown able to increase the permeability of brain capillaries, by altering endothelial cell membrane integr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005725
更新日期:1997-07-01 00:00:00
abstract::Ageing affects many visual functions. Here, we investigated the effects of ageing on vernier acuity and backward masking using the shine-through paradigm. We divided healthy older adults (>60 years) into two groups depending on whether vernier duration was comparable to younger adults (Older Adults 1) or not (Older Ad...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4314-9
更新日期:2015-08-01 00:00:00
abstract::Fast cyclic movements and discrete motor acts are controlled differently, presumably because fast cyclic tasks are more automated, thereby depending on different circuits. If fast cyclic movements are made less predictable (e.g., by mixing frequencies), one would predict that their control will be less automated, requ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3686-y
更新日期:2013-11-01 00:00:00