A fluvoxamine-related fatality: Case report with postmortem concentrations.

Abstract:

:Fluvoxamine is a selective serotonin reuptake inhibitor that has been considered relatively safe in overdose. At therapeutic and supratherapeutic concentrations, fluvoxamine affects cardiac conduction, prolongs QTc interval, causes hypotension, obtundation, and can increase propensity for seizures. A man in his 60s was found dead at his home with a postmortem fluvoxamine peripheral blood concentration of 4.9 mg/L, and a liver concentration of 440 mg/kg. His cause of death was determined to be acute fluvoxamine toxicity.

journal_name

Forensic Sci Int

authors

Otter J,McIntyre IM,Morhaime J,Cantrell L

doi

10.1016/j.forsciint.2019.02.047

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

e31-e33

eissn

0379-0738

issn

1872-6283

pii

S0379-0738(18)30757-6

journal_volume

300

pub_type

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