Transposon mutagenesis and identification of mutated genes in growth-delayed Edwardsiella ictaluri.

abstract：BACKGROUND:Francisella tularensis is a fastidious, Gram-negative coccobacillus and is the causative agent of tularemia. To assess viability yet overcome lengthy incubation periods, a culture-based PCR method was used to detect early growth of the lowest possible number of F. tularensis cells. This method utilized a pre...

journal_title：BMC microbiology

authors： Buse HY,Morris BJ,Rice EW

更新日期：2020-03-25 00:00:00

abstract：BACKGROUND:The global spread of bacterial resistance has given rise to a growing interest in new anti-bacterial agents with a new strategy of action. Pilicides are derivatives of ring-fused 2-pyridones which block the formation of the pili/fimbriae crucial to bacterial pathogenesis. They impair by means of a chaperone-...

journal_title：BMC microbiology

authors： Piatek R,Zalewska-Piatek B,Dzierzbicka K,Makowiec S,Pilipczuk J,Szemiako K,Cyranka-Czaja A,Wojciechowski M

更新日期：2013-06-12 00:00:00

abstract：BACKGROUND:Saccharomyces cerevisiae multicellular communities are sustained by a scaffolding extracellular matrix, which provides spatial organization, and nutrient and water availability, and ensures group survival. According to this tissue-like biology, the yeast extracellular matrix (yECM) is analogous to the higher...

journal_title：BMC microbiology

authors： Faria-Oliveira F,Carvalho J,Ferreira C,Hernáez ML,Gil C,Lucas C

更新日期：2015-11-25 00:00:00

abstract：BACKGROUND:Trichomonas vaginalis is a human urogenital pathogen responsible for trichomonosis, the number-one, non-viral sexually transmitted disease (STD) worldwide, while T. tenax is a commensal of the human oral cavity, found particularly in patients with poor oral hygiene and advanced periodontal disease. The exten...

journal_title：BMC microbiology

authors： Kucknoor AS,Mundodi V,Alderete J

更新日期：2009-03-18 00:00:00

abstract：BACKGROUND:Previous phylogenetic analyses of species within the genus Golovinomyces (Ascomycota, Erysiphales), based on ITS and 28S rDNA sequence data, revealed a co-evolutionary relationship between powdery mildew species and hosts of certain tribes of the plant family Asteraceae. Golovinomyces growing on host plants ...

journal_title：BMC microbiology

authors： Qiu PL,Liu SY,Bradshaw M,Rooney-Latham S,Takamatsu S,Bulgakov TS,Tang SR,Feng J,Jin DN,Aroge T,Li Y,Wang LL,Braun U

更新日期：2020-03-05 00:00:00

abstract：BACKGROUND:The date palm root borer Oryctes agamemnon (Coleoptera: Scarabaeidae) is one of the major pests of palms. In Saudi Arabia, both larvae and adults of Oryctes are particularly troublesome, especially during the establishment of young date palm orchards. Endosymbiotic bacteria are known to have a key role in fo...

journal_title：BMC microbiology

authors： El-Sayed WS,Ibrahim RA

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in reaching the different areas of the gastrointestinal tract (GIT) in vivo....

journal_title：BMC microbiology

authors： Marzorati M,Vanhoecke B,De Ryck T,Sadaghian Sadabad M,Pinheiro I,Possemiers S,Van den Abbeele P,Derycke L,Bracke M,Pieters J,Hennebel T,Harmsen HJ,Verstraete W,Van de Wiele T

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:Predicting antibiotic resistance before it emerges at clinical settings constitutes a novel approach for preventing and fighting resistance of bacterial pathogens. To analyse the possibility that novel plasmid-encoded quinolone resistance determinants (Qnr) can emerge and disseminate among bacterial pathogen...

journal_title：BMC microbiology

authors： Sánchez MB,Hernández A,Rodríguez-Martínez JM,Martínez-Martínez L,Martínez JL

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:It is unclear how DNA is packaged in a bacterial cell in the absence of nucleosomes. To investigate the initial level of DNA condensation in bacterial nucleoid we used in vivo DNA digestion coupled with high-throughput sequencing of the digestion-resistant fragments. To this end, we transformed E. coli cells...

journal_title：BMC microbiology

authors： Tolstorukov MY,Virnik K,Zhurkin VB,Adhya S

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:The human gastrointestinal (GI) tract microbiota has been a subject of intense research throughout the 3rd Millennium. Now that a general picture about microbiota composition in health and disease is emerging, questions about factors determining development of microbiotas with specific community structures w...

journal_title：BMC microbiology

authors： Peñate-Medina O,Tower RJ,Peñate-Medina T,Will O,Saris PEJ,Suojanen J,Sorsa T,Huuskonen L,Hiippala K,Satokari R,Glüer CC,de Vos WM,Reunanen J

更新日期：2019-07-18 00:00:00

abstract：BACKGROUND:Clostridium termitidis CT1112 is an anaerobic, Gram-positive, mesophilic, spore-forming, cellulolytic bacterium, originally isolated from the gut of a wood feeding termite Nasusitermes lujae. It has the ability to hydrolyze both cellulose and hemicellulose, and ferment the degradation products to acetate, fo...

journal_title：BMC microbiology

authors： Munir RI,Spicer V,Krokhin OV,Shamshurin D,Zhang X,Taillefer M,Blunt W,Cicek N,Sparling R,Levin DB

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:The ATP-Binding Cassette (ABC) functional superfamily includes integral transmembrane exporters that have evolved three times independently, forming three families termed ABC1, ABC2 and ABC3, upon which monophyletic ATPases have been superimposed for energy-coupling purposes [e.g., J Membr Biol 231(1):1-10, ...

journal_title：BMC microbiology

authors： Zheng WH,Västermark Å,Shlykov MA,Reddy V,Sun EI,Saier MH Jr

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Escherichia coli is a well-studied anaerobic bacteria which is able to regulate metabolic pathways depending on the type of sugar presented in the medium. We have studied the glucose-lactose shift in E. coli at the protein level using a recently developed mass spectrometry platform. METHOD:Cells were grown ...

journal_title：BMC microbiology

authors： Mostovenko E,Deelder AM,Palmblad M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The phenomenon of misdiagnosing tuberculosis (TB) by laboratory cross-contamination when culturing Mycobacterium tuberculosis (MTB) has been widely reported and it has an obvious clinical, therapeutic and social impact. The final confirmation of a cross-contamination event requires the molecular identificati...

journal_title：BMC microbiology

authors： Martín A,Herranz M,Lirola MM,Fernández RF,INDAL-TB group.,Bouza E,García de Viedma D

更新日期：2008-02-14 00:00:00

abstract：BACKGROUND:Recent studies suggest that the reported protective effects of statins (HMG-CoA reductase inhibitors) against community-acquired pneumonia (CAP) and sepsis in humans may be due to confounders and a healthy user-effect. To directly test whether statins are protective against Streptococcus pneumoniae, the lead...

journal_title：BMC microbiology

authors： Boyd AR,Hinojosa CA,Rodriguez PJ,Orihuela CJ

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:The bacterial surface protein internalin (InlA) is a major virulence factor of the food-born pathogen Listeria monocytogenes. It plays a critical role in the bacteria crossing the host intestinal barrier by a species-specific interaction with the cell adhesion molecule E-cadherin. In mice, the interaction of...

journal_title：BMC microbiology

authors： Bergmann S,Beard PM,Pasche B,Lienenklaus S,Weiss S,Gahan CG,Schughart K,Lengeling A

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:Cathepsins are a group of endosomal proteases present in many cells including dendritic cells (DCs). The activity of cathepsins is regulated by their endogenous inhibitors - cystatins. Cathepsins are crucial to antigen processing during viral and bacterial infections, and as such are a prerequisite to antige...

journal_title：BMC microbiology

authors： Bossowska-Nowicka M,Mielcarska MB,Romaniewicz M,Kaczmarek MM,Gregorczyk-Zboroch KP,Struzik J,Grodzik M,Gieryńska MM,Toka FN,Szulc-Dąbrowska L

更新日期：2019-05-10 00:00:00

abstract：BACKGROUND:Photorhabdus are Gram negative bacteria that are pathogenic to insect larvae whilst also having a mutualistic interaction with nematodes from the family Heterorhabditis. Iron is an essential nutrient and bacteria have different mechanisms for obtaining both the ferrous (Fe2+) and ferric (Fe3+) forms of this ...

journal_title：BMC microbiology

authors： Watson RJ,Millichap P,Joyce SA,Reynolds S,Clarke DJ

更新日期：2010-06-22 00:00:00

abstract：BACKGROUND:The life cycle of a bacteriophage has tightly programmed steps to help virus infect its host through the interactions between the bacteriophage and its host proteins. However, bacteriophage-host protein interactions in high temperature environment remain poorly understood. To address this issue, the protein ...

journal_title：BMC microbiology

authors： Chen Y,Wei D,Wang Y,Zhang X

更新日期：2013-02-26 00:00:00

abstract：BACKGROUND:Following genital chlamydial infection, an early T helper type 1 (Th1)-associated immune response precedes the activation and recruitment of specific Th1 cells bearing distinct chemokine receptors, subsequently leading to the clearance of Chlamydia. We have shown that CCR5, a receptor for CCL5, is crucial fo...

journal_title：BMC microbiology

authors： Sakthivel SK,Singh UP,Singh S,Taub DD,Igietseme JU,Lillard JW Jr

更新日期：2008-08-13 00:00:00

abstract：BACKGROUND:Several intracellular bacterial pathogens have evolved subtle strategies to subvert vesicular trafficking pathways of their host cells to avoid killing and to replicate inside the cells. Brucellae are Gram-negative facultative intracellular bacteria that are responsible for brucellosis, a worldwide extended ...

journal_title：BMC microbiology

authors： Hamer I,Goffin E,De Bolle X,Letesson JJ,Jadot M

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Many bacterial extracytoplasmic proteins are stabilized by intramolecular disulfide bridges that are formed post-translationally between their cysteine residues. This protein modification plays an important role in bacterial pathogenesis, and is facilitated by the Dsb (disulfide bond) family of the redox pro...

journal_title：BMC microbiology

authors： Grabowska AD,Wandel MP,Łasica AM,Nesteruk M,Roszczenko P,Wyszyńska A,Godlewska R,Jagusztyn-Krynicka EK

更新日期：2011-07-25 00:00:00

abstract：BACKGROUND:Streptococcus pseudopneumoniae, is a novel member of the genus Streptococcus, falling close to related members like S. pneumoniae, S. mitis, and S. oralis. Its recent appearance has shed light on streptococcal infections, which has been unclear till recently. In this study, the transcriptome of S. pseudopneu...

journal_title：BMC microbiology

authors： Park HK,Myung SC,Kim W

更新日期：2012-07-06 00:00:00

abstract：BACKGROUND:The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic activities, as well as differences in disposal regulations and enforcement increase the contamina...

journal_title：BMC microbiology

authors： Mendoza J,Botsford J,Hernandez J,Montoya A,Saenz R,Valles A,Vazquez A,Alvarez M

更新日期：2004-04-22 00:00:00

abstract：BACKGROUND:GeoChip 3.0, a microbial functional gene array, containing ~28,000 oligonucleotide probes and targeting ~57,000 sequences from 292 functional gene families, provided a powerful tool for researching microbial community structure in natural environments. The alpine meadow is a dominant plant community in the Q...

journal_title：BMC microbiology

authors： Zhang Y,Lu Z,Liu S,Yang Y,He Z,Ren Z,Zhou J,Li D

更新日期：2013-03-29 00:00:00

abstract：BACKGROUND:Sigma factors are one of the components of RNA polymerase holoenzymes, and an essential factor of transcription initiation in bacteria. Corynebacterium glutamicum possesses seven genes coding for sigma factors, most of which have been studied to some detail; however, the role of SigD in transcriptional regul...

journal_title：BMC microbiology

authors： Taniguchi H,Busche T,Patschkowski T,Niehaus K,Pátek M,Kalinowski J,Wendisch VF

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Propionibacterium acnes is a commensal of human skin but is also known to be involved in certain diseases, such as acne vulgaris and infections of orthopaedic implants. Treatment of these conditions is complicated by increased resistance to antibiotics and/or biofilm formation of P. acnes bacteria. P. acnes ...

journal_title：BMC microbiology

authors： Lood R,Mörgelin M,Holmberg A,Rasmussen M,Collin M

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:Vibrio cholerae is the causative agent of cholera. Extensive studies reveal that complicated regulatory cascades regulate expression of virulence genes, the products of which are required for V. cholerae to colonize and cause disease. In this study, we investigated the expression of the key virulence regulat...

journal_title：BMC microbiology

authors： Xu X,Stern AM,Liu Z,Kan B,Zhu J

更新日期：2010-01-06 00:00:00

abstract：BACKGROUND:adhC from Haemophilus influenzae encodes a glutathione-dependent alcohol dehydrogenase that has previously been shown to be required for protection against killing by S-nitrosoglutathione (GSNO). This group of enzymes is known in other systems to be able to utilize substrates that form adducts with glutathio...

journal_title：BMC microbiology

authors： Kidd SP,Jiang D,Tikhomirova A,Jennings MP,McEwan AG

更新日期：2012-07-31 00:00:00

abstract：BACKGROUND:Metabolically versatile soil bacteria Burkholderia cepacia complex (Bcc) have emerged as opportunistic pathogens, especially of cystic fibrosis (CF). Previously, we initiated the characterization of the phenylacetic acid (PA) degradation pathway in B. cenocepacia, a member of the Bcc, and demonstrated the ne...

journal_title：BMC microbiology

authors： Hamlin JN,Bloodworth RA,Cardona ST

更新日期：2009-10-18 00:00:00