Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants.

abstract：BACKGROUND:Bloodstream infections represent serious conditions carrying a high mortality and morbidity rate. Rapid identification of microorganisms and prompt institution of adequate antimicrobial therapy is of utmost importance for a successful outcome. Aiming at the development of a rapid, simplified and efficient pr...

journal_title：BMC microbiology

authors： Jakovljev A,Bergh K

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood. We sought to determine the effect of environmental variability on growth in vitro and to assess variability between strains. We evaluated the effect of temperat...

journal_title：BMC microbiology

authors： Tóthpál A,Desobry K,Joshi SS,Wyllie AL,Weinberger DM

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:Botrytis cinerea secretes a high number of proteins that are predicted to have numerous O-glycosylation sites, frequently grouped in highly O-glycosylated regions, and analysis of mutants affected in O-glycosylation has shown, in B. cinerea and in other phytopathogenic fungi, that this process is important f...

journal_title：BMC microbiology

authors： González M,Brito N,González C

更新日期：2014-10-12 00:00:00

abstract：BACKGROUND:Biofilm is a fundamental bacterial survival mode which proceeds through three main generalized phases: adhesion, maturation, and dispersion. Lactobacilli spp. (LB) are critical components of gut and reproductive health and are widely used probiotics. Evaluation of time-dependent mechanisms of biofilm formati...

journal_title：BMC microbiology

authors： Martinez S,Garcia JG,Williams R,Elmassry M,West A,Hamood A,Hurtado D,Gudenkauf B,Ventolini G,Schlabritz-Loutsevitch N

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:The resurgence of multi-drug resistant tuberculosis (MDR-TB) and HIV associated tuberculosis (TB) are of serious global concern. To contain this situation, new anti-tuberculosis drugs and reduced treatment regimens are imperative. Recently, a nitroimidazole, PA-824, has been shown to be active against both r...

journal_title：BMC microbiology

authors： Somasundaram S,Anand RS,Venkatesan P,Paramasivan CN

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Most group A streptococcal (GAS) vaccine strategies have focused on the surface M protein, a major virulence factor of GAS. The amino-terminus of the M protein elicits antibodies, that are both opsonic and protective, but which are type specific. J14, a chimeric peptide that contains 14 amino acids from the ...

journal_title：BMC microbiology

authors： Yoonim N,Olive C,Pruksachatkunakorn C,Pruksakorn S

更新日期：2006-08-09 00:00:00

abstract：BACKGROUND:The use of chemical fungicides against fungal pathogens adversely affects soil and plant health thereby resulting in overall environmental hazards. Therefore, biological source for obtaining antifungal agents is considered as an environment-friendly alternative for controlling fungal pathogens. RESULTS:In t...

journal_title：BMC microbiology

authors： Hazarika DJ,Goswami G,Gautom T,Parveen A,Das P,Barooah M,Boro RC

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis is the foremost oral pathogen of adult periodontitis in humans. However, the mechanisms of bacterial invasion and the resultant destruction of the gingival tissue remain largely undefined. RESULTS:We report host-P. gingivalis interactions in primary human gingival fibroblast (HGF) c...

journal_title：BMC microbiology

authors： Urnowey S,Ansai T,Bitko V,Nakayama K,Takehara T,Barik S

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:Total community rDNA was used to determine the diversity of bacteria and archaea from water, wet sediment and microbial mats samples of hot springs in the Eastern lowlands of Eritrea. The temperatures of the springs range from 49.5 °C to 100 °C while pH levels varied from 6.97 to 7.54. Akwar and Maiwooi have...

journal_title：BMC microbiology

authors： Ghilamicael AM,Budambula NLM,Anami SE,Mehari T,Boga HI

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:Thermotolerant Campylobacter is among the more prevalent bacterial pathogens that cause foodborne diseases. This study aimed at evaluating the occurrence of thermotolerant Campylobacter contamination in chicken carcasses and processing plant stations (chilling water, scalding water, defeathering machinery, e...

journal_title：BMC microbiology

authors： Figueroa G,Troncoso M,López C,Rivas P,Toro M

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:Saudi Arabia is mostly barren except the southwestern highlands that are susceptible to environmental changes, a hotspot for biodiversity, but poorly studied for microbial diversity and composition. In this study, 454-pyrosequencing of 16S rRNA gene hypervariable region V6 was used to analyze soil bacterial ...

journal_title：BMC microbiology

authors： Yasir M,Azhar EI,Khan I,Bibi F,Baabdullah R,Al-Zahrani IA,Al-Ghamdi AK

更新日期：2015-03-14 00:00:00

abstract：BACKGROUND:Atherosclerosis is still the leading cause of death in the western world. Besides known risk factors studies demonstrating Chlamydophila pneumoniae (C. pneumoniae) to be implicated in the progression of the disease, little is known about C. pneumoniae infection dynamics. We investigated whether C. pneumoniae...

journal_title：BMC microbiology

authors： Marino J,Stoeckli I,Walch M,Latinovic-Golic S,Sundstroem H,Groscurth P,Ziegler U,Dumrese C

更新日期：2008-02-19 00:00:00

abstract：BACKGROUND:Tetrahymena thermophila is one of the best characterized unicellular eukaryotes and its genome is sequenced in its entirety. However, the AT-richness of the genome and an unusual codon usage cause problems in cloning and expression of the ciliate DNA. To overcome these technical hiatuses we developed a Cre-d...

journal_title：BMC microbiology

authors： Weide T,Bockau U,Rave A,Herrmann L,Hartmann MW

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Papua New Guinea (PNG) is a high tuberculosis (TB) burden country of the WHO Western Pacific Region, but so far research on drug resistance (DR) and genotypes of Mycobacterium tuberculosis (M. tuberculosis) was only conducted in few provinces in the country. The aim of the present study was to obtain baselin...

journal_title：BMC microbiology

authors： Ley SD,Harino P,Vanuga K,Kamus R,Carter R,Coulter C,Pandey S,Feldmann J,Ballif M,Siba PM,Phuanukoonnon S,Gagneux S,Beck HP

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Legionella pneumophila, the causative agent of Legionnaire's disease, may enter a viable but non-culturable (VBNC) state triggered by environmental stress conditions. Specific outer-membrane epitopes of L. pneumophila are used in many diagnostic applications and some of them are linked to important virulence...

journal_title：BMC microbiology

authors： Schrammel B,Petzold M,Cervero-Aragó S,Sommer R,Lück C,Kirschner A

更新日期：2018-07-17 00:00:00

abstract：BACKGROUND:The Uzon Caldera is one of the places on our planet with unique geological, ecological, and microbiological characteristics. Uzon oil is the youngest on Earth. Uzon oil has unique composition, with low proportion of heavy fractions and relatively high content of saturated hydrocarbons. Microbial communities ...

journal_title：BMC microbiology

authors： Peltek SE,Bryanskaya AV,Uvarova YE,Rozanov AS,Ivanisenko TV,Ivanisenko VA,Lazareva EV,Saik OV,Efimov VM,Zhmodik SM,Taran OP,Slynko NM,Shekhovtsov SV,Parmon VN,Dobretsov NL,Kolchanov NA

更新日期：2020-11-24 00:00:00

abstract：BACKGROUND:Pandemic Vibrio parahaemolyticus has undergone rapid changes in both K- and O-antigens, making detection of outbreaks more difficult. In order to understand these rapid changes, the genetic regions encoding these antigens must be examined. In Vibrio cholerae and Vibrio vulnificus, both O-antigen and capsular...

journal_title：BMC microbiology

authors： Chen Y,Dai J,Morris JG Jr,Johnson JA

更新日期：2010-11-02 00:00:00

abstract：BACKGROUND:The cell tropism of Brucella abortus, a causative agent of brucellosis and facultative intracellular pathogen, in the placenta is thought to be a key event of infectious abortion, although the molecular mechanism for this is largely unknown. There is a higher degree of bacterial colonization in the placenta ...

journal_title：BMC microbiology

authors： Watanabe K,Tachibana M,Tanaka S,Furuoka H,Horiuchi M,Suzuki H,Watarai M

更新日期：2008-12-05 00:00:00

abstract：BACKGROUND:A disrupted cell cycle progression of hepatocytes was reported in chronic hepatitis C virus (HCV) infection, which can contribute significantly in the associated pathogenesis. The present study aimed to further elaborate these disruptions by evaluating the expression of key cell cycle and apoptotic proteins ...

journal_title：BMC microbiology

authors： Sarfraz S,Hamid S,Siddiqui A,Hussain S,Pervez S,Alexander G

更新日期：2008-08-05 00:00:00

abstract：BACKGROUND:There is an urgent need to develop potent antimicrobials for the treatment of infections caused by antibiotic-resistant bacterial pathogens. Paenipeptin C' (C8-Pat) is a novel linear lipopeptide recently discovered by our group. The objectives of this study were to determine the time-kill kinetics of paenipe...

journal_title：BMC microbiology

authors： Moon SH,Huang E

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Bacteria employ multiple mechanisms to control gene expression and react to their constantly changing environment. Bacterial growth in rich laboratory medium is a dynamic process in which bacteria utilize nutrients from simple to complex and change physical properties of the medium, as pH, during the process...

journal_title：BMC microbiology

authors： Sitkiewicz I,Musser JM

更新日期：2009-02-10 00:00:00

abstract：BACKGROUND:Bacterial and cellular genotyping is becoming increasingly important in the diagnosis of infectious diseases. However, difficulties in obtaining sufficient amount of bacterial and cellular DNA extracted from the same human biopsy specimens is often a limiting factor. In this study, total DNA (host and bacter...

journal_title：BMC microbiology

authors： Ryberg A,Borch K,Sun YQ,Monstein HJ

更新日期：2008-10-08 00:00:00

abstract：BACKGROUND:Many bacterial extracytoplasmic proteins are stabilized by intramolecular disulfide bridges that are formed post-translationally between their cysteine residues. This protein modification plays an important role in bacterial pathogenesis, and is facilitated by the Dsb (disulfide bond) family of the redox pro...

journal_title：BMC microbiology

authors： Grabowska AD,Wandel MP,Łasica AM,Nesteruk M,Roszczenko P,Wyszyńska A,Godlewska R,Jagusztyn-Krynicka EK

更新日期：2011-07-25 00:00:00

abstract：BACKGROUND:It is known that insects and crustaceans can carry simultaneous, active infections of two or more viruses without showing signs of disease, but it was not clear whether co-infecting viruses occupied the same cells or different cells in common target tissues. Our previous work showed that successive challenge...

journal_title：BMC microbiology

authors： Kanthong N,Khemnu N,Pattanakitsakul SN,Malasit P,Flegel TW

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:Aspergillus fumigatus is a ubiquitous saprotrophic fungus and an opportunistic pathogen of humans and animals. Humans and animals can inhale hundreds of A. fumigatus spores daily. Normally this is harmless for humans, but in case of immunodeficiency, invasive pulmonary aspergillosis (IPA) can develop with a ...

journal_title：BMC microbiology

authors： Valdes ID,van den Berg J,Haagsman A,Escobar N,Meis JF,Hagen F,Haas PJ,Houbraken J,Wösten HAB,de Cock H

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a food-borne pathogen and the most common cause of infections in hospitalized patients. The increase in the resistance of this pathogen to antibacterials has made necessary the development of new anti-staphylococcal agents. In this context, bacteriophage lytic enzymes such as endolys...

journal_title：BMC microbiology

authors： Rodríguez L,Martínez B,Zhou Y,Rodríguez A,Donovan DM,García P

更新日期：2011-06-17 00:00:00

abstract：BACKGROUND:Enteropathogenic Escherichia coli (EPEC) are classified into typical and atypical strains based on the presence of the E. coli adherence factor (EAF) plasmid. The EAF plasmid contains the bfp (bundle-forming pilus) operon and the perABC (plasmid encoded regulator) gene cluster. A 1-kb cryptic region of EAF p...

journal_title：BMC microbiology

authors： Teixeira NB,Rojas TC,da Silveira WD,Matheus-Guimarães C,Silva NP,Scaletsky IC

更新日期：2015-10-05 00:00:00

abstract：BACKGROUND:Glycopeptidolipids (GPLs) are among the major free glycolipid components of the outer membrane of several saprophytic and clinically-relevant Mycobacterium species. The architecture of GPLs is based on a constant tripeptide-amino alcohol core of nonribosomal peptide synthetase origin that is N-acylated with ...

journal_title：BMC microbiology

authors： Tatham E,Sundaram Chavadi S,Mohandas P,Edupuganti UR,Angala SK,Chatterjee D,Quadri LE

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:Although Aspergillus fumigatus is an important human fungal pathogen there are few expression systems available to study the contribution of specific genes to the growth and virulence of this opportunistic mould. Regulatable promoter systems based upon prokaryotic regulatory elements in the E. coli tetracycl...

journal_title：BMC microbiology

authors： Vogt K,Bhabhra R,Rhodes JC,Askew DS

更新日期：2005-01-13 00:00:00

abstract：BACKGROUND:With the growing demand for fossil fuels and the severe energy crisis, lignocellulose is widely regarded as a promising cost-effective renewable resource for ethanol production, and the use of lignocellulose residues as raw material is remarkable. Polar organisms have important value in scientific research a...

journal_title：BMC microbiology

authors： Cong B,Wang N,Liu S,Liu F,Yin X,Shen J

更新日期：2017-05-30 00:00:00