Abstract:
PURPOSE:Oral L-citrulline (Cit) increases plasma L-arginine (Arg) concentration and the production of nitric oxide (NO). NO dilates blood vessels and potentially improves sports performance. The combination of oral Arg and Cit (Arg + Cit) immediately and synergistically increases plasma Arg and nitrite/nitrate (NOx) concentrations more than either Cit or Arg alone. This prompted us to assess the effects of oral Arg + Cit on 10-min cycling performance in a double-blind, randomized, placebo-controlled crossover trial. METHODS:Twenty-four male soccer players ingested either Cit + Arg or placebo (both 1.2 g/day each) for 6 days. On day 7, they ingested Cit + Arg 1 h before performing a 10-min full-power pedaling test on a bicycle ergometer. Plasma NOx and amino acid levels were measured before and after the test, as well as the participants' subjective perception of physical exertion. RESULTS:Power output was significantly greater with Cit + Arg than in the placebo group (242 ± 24 vs. 231 ± 21 W; p < 0.05). Plasma concentrations of post-exercise NOx (p < 0.05), Cit (p < 0.01) and Arg (p < 0.01) were significantly higher in the Cit + Arg than in the placebo group, whereas exercise upregulated plasma NOx concentrations in both groups (p < 0.05). Cit + Arg also gave improved post-exercise subjective perception of "leg muscle soreness" and "ease of pedaling" (both p < 0.05). CONCLUSION:Seven days of oral Citrulline (1.2 g/d) and Arginine (1.2 g/d) ingestion improved 10-min cycling performance and the perception of physical exertion in male collegiate soccer players.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Suzuki I,Sakuraba K,Horiike T,Kishi T,Yabe J,Suzuki T,Morita M,Nishimura A,Suzuki Ydoi
10.1007/s00421-019-04097-7subject
Has Abstractpub_date
2019-05-01 00:00:00pages
1075-1084issue
5eissn
1439-6319issn
1439-6327pii
10.1007/s00421-019-04097-7journal_volume
119pub_type
杂志文章,随机对照试验abstract:PURPOSE:To investigate the effect of isolated muscle metaboreflex activation on spontaneous cardiac baroreflex sensitivity (cBRS), and to characterize the potential sex-related differences in this interaction in young healthy subjects. METHODS:40 volunteers (20 men and 20 women, age: 22 ± 0.4 year) were recruited. Aft...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-018-4004-y
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:This study investigated whether muscle cooling and its associated effects on skeletal muscle oxidative responses, blood gases, and hormonal concentrations influenced energy metabolism during cycling. METHODS:Twelve healthy participants (Males: seven; Females: five) performed two steady-state exercise sessions ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-020-04407-4
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To examine the effect of acute quercetin (Q) ingestion on neuromuscular function, biomarkers of muscle damage, and rate of perceived exertion (RPE) in response to an acute bout of resistance training. METHODS:10 young men (22.1 ± 1.8 years, 24.1 ± 3.1 BMI) participated in a randomized, double-blind, crossover ...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-018-3834-y
更新日期:2018-05-01 00:00:00
abstract::Falls from heights resulting from a loss of balance are a major concern in the occupational setting. Previous studies have documented a deleterious effect of lower extremity fatigue on balance. The purpose of this study was to investigate the effect of lumbar extensor fatigue on balance during quiet standing. Addition...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-004-1195-1
更新日期:2004-10-01 00:00:00
abstract::The recently reported static stretching impairments found in adults have not been studied in youth. Furthermore, stretch-training effects on sprint performance are equivocal, hence the purpose of this study was to examine the effect of stretch and sprint training on the acute effects of static stretching in 13-15 year...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0799-2
更新日期:2008-10-01 00:00:00
abstract::This study examined the effects of a 6-week stretching program on the dynamic passive elastic properties of the calf muscle-tendon unit (MTU) of unconditioned younger women. After random assignment of 12 women (age 18-31 years) to a stretching group (SG) or to a control group (CG), six subjects in the SG and four subj...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-006-0366-7
更新日期:2007-03-01 00:00:00
abstract::The aim of this study was to analyze the dynamic behavior of the high-frequency component (HF > 0.15 Hz) of heart rate variability (HRV) and the respiratory frequency in relation to the anaerobic threshold (AT). Twenty-two healthy subjects [mean (SD) age: 24 (6) years, height: 175 (10) cm, body mass: 65 (11) kg] compl...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s004210000302
更新日期:2000-11-01 00:00:00
abstract:PURPOSE:The twofold purpose of this study was (1) to compare differences in development and etiology of neuromuscular fatigue at different plantar flexor (PF) muscle-tendon unit (MTU) lengths between boys and men, and (2) to examine the relationship between musculotendinous stiffness and peripheral fatigue. METHODS:Ni...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-020-04305-9
更新日期:2020-03-01 00:00:00
abstract::Using two photomultiplier tubes (PMT), we measured the biophoton emission of the left and right wrists simultaneously. The subjects performed hand-grip exercises with both hands, during the measurements. We found a slow increase of the emission rates during the exercises, rising in average from 51.6 cps (counts per se...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-007-0607-4
更新日期:2008-03-01 00:00:00
abstract::Appropriate technique choice may affect ski performance. V2 ski skating technique has in recent years become more widely applied on uphill terrain where V1 technique has typically been used. This investigation compared physiological responses of skiers using V1 and V2 techniques during uphill treadmill roller-skiing. ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-005-1332-5
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:The cross-stressor adaptation hypothesis suggests that regular exercise leads to adaptations in the stress response systems that induce decreased physiological responses to psychological stressors. Even though an exercise intervention to buffer the detrimental effects of psychological stressors on health might ...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-015-3284-8
更新日期:2016-02-01 00:00:00
abstract::The purpose of this study was to evaluate the effects of various modes of training on the time-course of changes in lipoprotein-lipid profiles in the blood, cardiovascular fitness, and body composition after 16 weeks of training and 6 weeks of detraining in young women. A group of 48 sedentary but healthy women [mean ...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s004210000234
更新日期:2000-08-01 00:00:00
abstract:PURPOSE:To investigate the effects of aging on postural control and cognitive performance in single- and dual-tasking. METHODS:A cross-sectional comparative design was conducted in a university motion analysis laboratory. Young adults (n = 30; age 21.9 ± 2.4 years) and older adults (n = 30; age 71.9 ± 6.4 years) were ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-013-2740-6
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:Pentraxin 3 (PTX3) is a vital regulator of innate immune function. Although plasma PTX3 concentrations are elevated with aerobic fitness, the cellular functions of PTX3 remain unknown in aerobically trained and untrained subjects. METHODS:Thirty individuals (aerobically trained = 15 and untrained = 15) partici...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-018-3882-3
更新日期:2018-07-01 00:00:00
abstract::The present study aimed to characterize cardiac hypertrophy induced by activation of the renin-angiotensin system in terms of functional alterations on the level of the contractile proteins, employing transgenic rats harboring the mouse renin gene (TGR(mREN2)27). Ca2+-dependent tension and myosin ATPase activity were ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-006-0323-5
更新日期:2007-01-01 00:00:00
abstract::In this study, we compared the biomechanical and physiological responses of healthy men and women during bilateral load carriage while they walked on a treadmill at their self-selected velocity. Eleven men mean (SD) maximal oxygen uptake, [VO(2)(max) = 56.0 (7.1) ml x kg(-1) x min(-1)] and 11 women [VO(2)(max) = 44.6 ...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/PL00013800
更新日期:2000-01-01 00:00:00
abstract::The purpose of this study was to investigate the effects of a submaximal aerobic exercise bout on adiponectin and resistin levels as well as insulin sensitivity, until 48 h post-exercise in healthy overweight males. Nine subjects performed an exercise bout at an intensity corresponding to approximately 65% of their ma...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-006-0169-x
更新日期:2006-05-01 00:00:00
abstract::The aim of the study was to compare the kinematics and the timing and amount of electromyographic (EMG) activity during the lat-pull down exercise performed on machines that afforded one, two, or three degrees of freedom for the movement. Seven healthy men (age 29.4 +/- 5.6 years) participated in the study. The exerci...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-010-1421-y
更新日期:2010-07-01 00:00:00
abstract::The purpose of this study was to determine whether cross-education, defined as the increase in strength of an untrained limb after training of the contralateral homologous limb, is specific to low and high velocity eccentric training. Twenty-six subjects were randomized into two groups ( n=13 each) that performed unil...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00421-003-0841-3
更新日期:2003-08-01 00:00:00
abstract::Using an improved Peronnet-Thibault model to analyse the maximal power available during exercise, it was found that a 3rd-order relaxation process for the decreasing dynamics of aerobic power can describe accurately the data available for world track records and aerobic-to-total energy ratio (ATER). It was estimated t...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-001-0555-3
更新日期:2002-04-01 00:00:00
abstract::Hyperventilation prior to breath-hold diving increases the risk of syncope as a result of hypoxia. Recently, a number of cases of near-drownings in which the swimmers did not hyperventilate before breath-hold diving have come to our attention. These individuals had engaged in prolonged exercise prior to breath-hold di...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-004-1242-y
更新日期:2005-03-01 00:00:00
abstract::This study aimed to investigate the involvement of cerebral oxygenation in limitation of maximal exercise. We hypothesized that O2 supplementation improves physical performance in relation to its effect on cerebral oxygenation during exercise. Eight untrained men (age 27 ± 6 years; VO2 max 45 ± 8 ml min(-1) kg(-1)) pe...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-013-2637-4
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the effects of a fatigue-inducing bout of submaximal, intermittent isometric contractions on the electromechanical delay (EMD) of the leg extensors and flexors in young and old men. METHODS:Twenty young (mean ± SD: age = 25 ± 2.8 years) and sixteen old (age = 70.8 ±...
journal_title:European journal of applied physiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00421-013-2675-y
更新日期:2013-09-01 00:00:00
abstract::This study examined the association of blood lactate concentration [La] and heart rate (HR) with ratings of perceived exertion (RPE) during 60 min of steady workload cycling. Physically active college-aged subjects (n = 14) completed an exhaustive cycling test to determine VO(2) (peak) and lactate threshold (2.5 mmol ...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-004-1311-2
更新日期:2005-05-01 00:00:00
abstract::Cardiopulmonary exercise test is the gold standard for the identification of the ventilatory compensation point (VCP), an important threshold for exercise training prescription. We hypothesized that changes in the slope of increment in minute ventilation (V'(E)) over heart rate (HR) during incremental exercise can be ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0777-8
更新日期:2008-09-01 00:00:00
abstract::This study compared the first and second exercise bouts consisting of electrically evoked isometric contractions for muscle damage profile. Nine healthy men (31 +/- 4 years) had two electrical muscle stimulation (EMS) bouts separated by 2 weeks. The knee extensors of one leg were stimulated by biphasic rectangular pul...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00421-009-1278-0
更新日期:2010-03-01 00:00:00
abstract::The purpose of this study was to investigate the effects of resistance training on the morphological and functional properties of human lower limb muscles during 20 days of 6 degrees head-down-tilt bed rest. Nine men were randomly assigned to the resistance training group (BR-Tr, n = 5) or the non-training, control gr...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s004210050648
更新日期:2000-05-01 00:00:00
abstract::Evidence indicates that repeated-bouts of eccentric exercise (EE) do not exacerbate the extent of muscle damage indices, as compared to a single-bout. We hypothesized that molecular adaptations, under repeated-bouts of EE, would include suppression of muscle repair inhibitory factors such as myostatin and up-regulatio...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-007-0510-z
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:Equations for blood oxyhemoglobin (HbO2) and carbaminohemoglobin (HbCO2) dissociation curves that incorporate nonlinear biochemical interactions of oxygen and carbon dioxide with hemoglobin (Hb), covering a wide range of physiological conditions, are crucial for a number of practical applications. These include...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-015-3228-3
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:The focus of this study was to monitor daily objective measures of standing postural control over an 8-week period, recorded in a person's home, in a population of healthy older adults. Establishing natural patterns of variation in the day-to-day signal, occurring in the relative absence of functional decline o...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-014-3034-3
更新日期:2015-02-01 00:00:00