Abstract:
: Background: The use of bioimpedance spectroscopy (BIS) for the detection of unilateral upper limb lymphedema is growing. Currently, normatively determined diagnostic thresholds using bioimpedance are available for females only. It is unclear if they are suitable for males at risk of unilateral upper limb lymphedema. The aim of the present study was to determine normatively based bioimpedance thresholds for male unilateral upper limb lymphedema. Methods and Results: Impedance values (R0) for the upper limbs of 60 healthy adult male participants were assessed using BIS. As has been found in females, dominance was found to significantly impact on R0 values (p = 0.002); therefore, two diagnostic thresholds are required depending on the at-risk limb. Interlimb impedance thresholds were calculated, set at both two standard deviations (2SD) and three standard deviations (3SD) above the mean. The 3SD threshold for unilateral lymphedema in the upper limbs of males is 1.127 for the dominant at-risk limb and 1.094 for the nondominant at-risk limb. The 2SD threshold is 1.090 for the dominant at-risk limb and 1.058 for the nondominant at-risk limb. These differ from what has previously been found for females. Conclusions: This study is the first to establish normatively determined bioimpedance thresholds for male unilateral upper limb lymphedema. These thresholds should now be used to improve early detection of male unilateral upper limb lymphedema.
journal_name
Lymphat Res Bioljournal_title
Lymphatic research and biologyauthors
Xie AZT,Lee MJ,Dylke Edoi
10.1089/lrb.2018.0051subject
Has Abstractpub_date
2020-02-01 00:00:00pages
27-30issue
1eissn
1539-6851issn
1557-8585journal_volume
18pub_type
杂志文章abstract:BACKGROUND:Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Lymphedema Quality of life Inventory (LyQLI) has been tested for reliability and validity. The purpose of this study was to test the LyQLI for responsiveness and sensitivity. METHO...
journal_title:Lymphatic research and biology
pub_type: 杂志文章,多中心研究
doi:10.1089/lrb.2017.0048
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The aim of this prospective controlled study was to assess the efficacy of two different combination treatment modalities of lymphedema (LE). Manual lymphatic drainage (MLD) and compression bandage combination (complex decongestive therapy) have been compared with intermittent pneumatic compression (IPC) plu...
journal_title:Lymphatic research and biology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/lrb.2012.0002
更新日期:2012-09-01 00:00:00
abstract:: Background: Platelet-rich plasma (PRP) is an autologous concentrated preparation of platelets characterized by lymphangiogenetic and tissue-repairing effects. Although PRP has been safely used in many different fields, there is no clinical study regarding the use of PRP in...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0064
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The spleen has an important physiological role in maintaining blood volume; this study aimed to determine whether during pathophysiological circumstances, namely endotoxemia, the extrasplenic pathway is dysfunctional. We hypothesize that increased 'leakiness' of lymphatics in response to lipopolysaccharide (...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2008.1019
更新日期:2009-01-01 00:00:00
abstract::Pediatric hepatic angiosarcoma is a very rare malignant vascular tumor. A few cases have shown pediatric hepatic angiosarcoma occurring on a background of preexisting vascular lesions. We report the case of a newborn girl who presented extensive limbs and upper trunk cutaneous mixed vascular malformations at birth. Th...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2009.0034
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Previous studies suggest that rhythmic compression of the abdomen (abdominal lymphatic pump techniques, LPT) enhances immunity and resistance to infectious disease, but direct evidence of this has not been documented. In this study, the thoracic duct of eight anesthetized mongrel dogs was catheterized, so th...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2007.1001
更新日期:2007-01-01 00:00:00
abstract:: Background: Local tissue water in patients with breast cancer-related lymphedema (BCRL) can be assessed by measurement of the tissue dielectric constant using the MoistureMeterD Compact® (MMDC) device, or by performing the pitting test. Although these assessment methods ar...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0013
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Analysis of the innervation pattern of the thoracic duct in young and elderly human subjects has been performed. The subdivision of the vessels in cervical and lumbar region were taken in consideration. METHODS AND RESULTS:Immunostaining for general nerve fibers with a PGP 9.5 marker disclosed a diffuse inn...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2011.0014
更新日期:2012-06-01 00:00:00
abstract::Abstracts Background: Arm lymphedema after breast cancer surgery affects women both from physical and psychological points of view. Lymphedema leads to adipose tissue deposition. Liposuction and controlled compression therapy (CCT) reduces the lymphedema completely. METHODS AND RESULTS:Sixty female patients with arm ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0035
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:The aim of the article was to assess risk factors and to analyze methods applied in the prevention and treatment of lower limb edema in pregnant women with a particular focus on compression therapy and exercise. MATERIALS AND METHODS:Fifty-four women during the early 24-hour period following delivery were as...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0038
更新日期:2017-06-01 00:00:00
abstract::The present report describes a case with the triad of yellow nail syndrome (YNS) and the use of low-pressure compression pump as treatment of lymphedema in YNS. A 71-year-old woman presented with bilateral lower extremity lymphedema, yellow nails, and recurrent bilateral pleural effusion. In this case, we specifically...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2011.0012
更新日期:2012-03-01 00:00:00
abstract::The knowledge of humoral and cellular factors retained in tissues affected by ineffective lymph transport is necessary to comprehend the pathological mechanisms of the evolving changes in the extremity. In this article, we report our observations on changes in the protein composition of lymph in obstructive lymphedema...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/153968503768330265
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study is to investigate the effects of the aqua-lymphatic therapy (ALT) on unilateral lower extremity lymphedema in the maintenance phase. MATERIALS AND METHODS:This is a randomized controlled trial with a blinded assessor. The study was completed with 30 ALT and 27 control group partici...
journal_title:Lymphatic research and biology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/lrb.2017.0017
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:The putrefaction factor is one of the biggest problems when undertaking unembalmed cadaveric tissue dissections for lymphatic vessel mapping. METHODS:One female bilateral breast and anterior upper torso from an unembalmed human cadaver was studied over an 8-week period. Multiple prefrozen domestic ice brick...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2008.1020
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Secondary lymphedema, resulting from damage to lymphatic vessels, is a common sequela following surgical removal of lymph nodes for cancer. Current therapeutics for treating lymphedema are limited and further research on underlying causes is warranted. Published studies on molecular mechanisms of lymphedema ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0042
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Lymphedema leads to adipose tissue deposition. Water-fat magnetic resonance imaging (MRI) can quantify and localize fat and water. The presence of excess fat and excess water/muscle in the subfascial compartment of the lymphedematous limb has not been investigated before. The aim of this study was to investi...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0042
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:A relative inability to capture a sufficiently large patient population in any one geographic location has traditionally limited research into rare diseases. METHODS AND RESULTS:Clinicians interested in the rare disease lymphangioleiomyomatosis (LAM) have worked with the LAM Treatment Alliance, the MIT Medi...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2009.0028
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Lymphedema is the abnormal accumulation of protein-rich fluid in the interstitial space. Primary lymphedema is a rare genetic condition with both autosomal dominant and autosomal recessive modes of inheritance. Three genes, FLT4 (VEGFR3), FOXC2, and SOX18 cause varying forms of primary lymphedema. In industr...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2008.1524
更新日期:2008-01-01 00:00:00
abstract:: Background: Lymphedema is a disorder in which lymph accumulates in the interstitial spaces due to poor lymphatic flow resulting from hypoplasia or aplasia of the lymphatic vessels, or to morpho-functional alterations that impair lymphatic flow. Lymphedema is a debilitating...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0052
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Corneal lymphangiogenesis (LG) and hemangiogenesis (HG) accompany many diseases after inflammatory, infectious, traumatic or chemical insults. They also contribute to transplant rejection. It is known that corneal transplants in infants or children have a higher rejection rate than in adults. However, it has...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2011.0005
更新日期:2011-01-01 00:00:00
abstract::Exciting studies involving the molecular regulation of lymphangiogenesis in lymphatic-associated disorders (e.g., wound healing, lymphedema and tumor metastasis) have focused renewed attention on the intrinsic relationship between lymphatic endothelial cells (LECs) and extracellular matrix (ECM) microenvironment. ECM ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章,评审
doi:10.1089/lrb.2006.4.83
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Lower limb lymphedema (LLL) is a common complication of cancer treatment. The disease is chronic and progressive with no cure. Although a common and significant source of morbidity, the impact of this condition on health-related quality of life (HRQOL) has only recently been addressed. In effort to identify ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章,评审
doi:10.1089/lrb.2012.0015
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Near-infrared fluorescence (NIRF) imaging is a new imaging technique that is used to visualize lymphatic vessels in humans. It has a high spatial and temporal resolution, allowing real-time visualization of lymphatic flow. METHODS AND RESULTS:The current study investigated the intra- and inter-individual va...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0061
更新日期:2017-09-01 00:00:00
abstract:: Background: Lymphedema may impact patients' health-related quality of life (HRQoL). The purpose of this study was to evaluate HRQoL after two different treatments to the 12-month follow-up point. Methods and Results: Study part...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2018.0065
更新日期:2020-08-01 00:00:00
abstract:: Background: Surgical excision and/or radiation targeting of regional lymph nodes are an essential component in the clinical management of cancer. Importantly, a more accurate understanding of lymphatic anatomy could enable refinement of present treatment strategies. Given ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0007
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Changes in arm soft tissue composition, especially increased adipose tissue, has been found in advanced, non-pitting breast cancer-related lymphedema (BCRL). The aim of this study was to examine whether these changes were localized to any particular region of the arm and whether they occurred in lymphedema w...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2014.0033
更新日期:2015-03-01 00:00:00
abstract:: Background: The purpose of this study was to investigate acute cardiovascular responses to manual lymphatic drainage (MLD) on different parts of the body. Materials and Methods: Thirty healthy individuals (10 women and 20 men) ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2018.0043
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:It has recently become apparent that the lymph pump is an electrical entity that rivals the heart in complexity. Many interesting currents have been demonstrated by voltage clamping isolated lymphatic smooth muscle cells, but until now the role of these currents in the intact syncitium has not been studied. ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2007.5104
更新日期:2007-01-01 00:00:00
abstract:: Background: Conservative nonsurgical treatment has traditionally been applied to lymphedema. Early surgical procedures were invasive and disfiguring and their long-term success was often limited. In contrast, contemporary surgical techniques are much less invasive and have...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2018.0038
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been studied in experimental mammals, little is known concerning the presence and properties of lymphatic stomata in the adult human pleura. Thus, adult human...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2014.0009
更新日期:2015-06-01 00:00:00