Abstract:
BACKGROUND:The putrefaction factor is one of the biggest problems when undertaking unembalmed cadaveric tissue dissections for lymphatic vessel mapping. METHODS:One female bilateral breast and anterior upper torso from an unembalmed human cadaver was studied over an 8-week period. Multiple prefrozen domestic ice bricks were used to cover in turn and keep constantly cold or partially frozen, the contralateral side of the tissue during the dissections. Using hydrogen peroxide to identify the lymphatics under the surgical microscope, the vessels were injected with a lead oxide mixture, and then radiographed to demonstrate lymphatic vessels in both breasts. The final results transferred to the computer for analysis. RESULTS:Lymph collecting vessels were found in breasts, anterior upper torso, and the internal mammary vascular bundles. The lymphatics of the breast and the anterior upper torso drain radially into the axillary lymph nodes. Unexpectedly, the lymphatic vessel drainage patterns of each breast are asymmetrical in this specimen. CONCLUSION:This study provides a new method to slow down putrefaction of unembalmed cadaveric tissue, thus enabling lymphatic dissection of a bilateral breast and torso specimen.
journal_name
Lymphat Res Bioljournal_title
Lymphatic research and biologyauthors
Pan WRdoi
10.1089/lrb.2008.1020subject
Has Abstractpub_date
2009-01-01 00:00:00pages
17-20issue
1eissn
1539-6851issn
1557-8585journal_volume
7pub_type
杂志文章abstract:BACKGROUND:It has recently become apparent that the lymph pump is an electrical entity that rivals the heart in complexity. Many interesting currents have been demonstrated by voltage clamping isolated lymphatic smooth muscle cells, but until now the role of these currents in the intact syncitium has not been studied. ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2007.5104
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Lymphedema Quality of life Inventory (LyQLI) has been tested for reliability and validity. The purpose of this study was to test the LyQLI for responsiveness and sensitivity. METHO...
journal_title:Lymphatic research and biology
pub_type: 杂志文章,多中心研究
doi:10.1089/lrb.2017.0048
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been studied in experimental mammals, little is known concerning the presence and properties of lymphatic stomata in the adult human pleura. Thus, adult human...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2014.0009
更新日期:2015-06-01 00:00:00
abstract:: Background: Surgical excision and/or radiation targeting of regional lymph nodes are an essential component in the clinical management of cancer. Importantly, a more accurate understanding of lymphatic anatomy could enable refinement of present treatment strategies. Given ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0007
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:In arm lymphedema secondary to axillary surgery and radiotherapy (breast cancer-related lymphedema), the swelling is largely epifascial and lymph flow per unit epifascial volume is impaired. The subfascial muscle compartment is not measurably swollen despite the iatrogenic damage to its axillary drainage pat...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/153968503321642615
更新日期:2003-01-01 00:00:00
abstract::Exciting studies involving the molecular regulation of lymphangiogenesis in lymphatic-associated disorders (e.g., wound healing, lymphedema and tumor metastasis) have focused renewed attention on the intrinsic relationship between lymphatic endothelial cells (LECs) and extracellular matrix (ECM) microenvironment. ECM ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章,评审
doi:10.1089/lrb.2006.4.83
更新日期:2006-01-01 00:00:00
abstract::The present report describes a case with the triad of yellow nail syndrome (YNS) and the use of low-pressure compression pump as treatment of lymphedema in YNS. A 71-year-old woman presented with bilateral lower extremity lymphedema, yellow nails, and recurrent bilateral pleural effusion. In this case, we specifically...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2011.0012
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Compared to volume/circumference measurements to diagnose lymphedema, thickening and disturbance of echogenicity of cutis and subcutis associated with the development of lymphedema is measured directly by ultrasonography. The aim of the present study was to investigate the evolution of thickness and echogeni...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2013.0028
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Lymphedema is the abnormal accumulation of protein-rich fluid in the interstitial space. Primary lymphedema is a rare genetic condition with both autosomal dominant and autosomal recessive modes of inheritance. Three genes, FLT4 (VEGFR3), FOXC2, and SOX18 cause varying forms of primary lymphedema. In industr...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2008.1524
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:A relative inability to capture a sufficiently large patient population in any one geographic location has traditionally limited research into rare diseases. METHODS AND RESULTS:Clinicians interested in the rare disease lymphangioleiomyomatosis (LAM) have worked with the LAM Treatment Alliance, the MIT Medi...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2009.0028
更新日期:2010-03-01 00:00:00
abstract::Abstracts Background: Arm lymphedema after breast cancer surgery affects women both from physical and psychological points of view. Lymphedema leads to adipose tissue deposition. Liposuction and controlled compression therapy (CCT) reduces the lymphedema completely. METHODS AND RESULTS:Sixty female patients with arm ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0035
更新日期:2017-03-01 00:00:00
abstract:: Background: Local tissue water in patients with breast cancer-related lymphedema (BCRL) can be assessed by measurement of the tissue dielectric constant using the MoistureMeterD Compact® (MMDC) device, or by performing the pitting test. Although these assessment methods ar...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0013
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Lymphedema of the arm and/or hand is a well-established complication of breast cancer therapy. The objective of the study was to determine the interest of auto-adjustable MOBIDERM® Autofit night arm sleeve in controlling edema rebound effect in breast cancer-related lymphedema patients just after a successfu...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0026
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:The composition of breast cancer-related lymphedema (BCRL) has been shown to evolve from the initial accumulation of fluid to the development of fibrotic lesions and abnormal fat deposition. Therefore, precise and reliable assessments of BCRL are required to develop accurate staging and management. Although ...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2012.0020
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Corneal lymphangiogenesis (LG) and hemangiogenesis (HG) accompany many diseases after inflammatory, infectious, traumatic or chemical insults. They also contribute to transplant rejection. It is known that corneal transplants in infants or children have a higher rejection rate than in adults. However, it has...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2011.0005
更新日期:2011-01-01 00:00:00
abstract::The vasculature of the central nervous system (CNS) is highly specialized with a blood-brain-barrier, reciprocal neuroepithelial-endothelial cell interactions and extensive pericyte coverage. Developmentally, numerous important signaling pathways participate in CNS angiogenesis to orchestrate the precise timing and sp...
journal_title:Lymphatic research and biology
pub_type: 杂志文章,评审
doi:10.1089/lrb.2008.1014
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:The aim of the article was to assess risk factors and to analyze methods applied in the prevention and treatment of lower limb edema in pregnant women with a particular focus on compression therapy and exercise. MATERIALS AND METHODS:Fifty-four women during the early 24-hour period following delivery were as...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0038
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Near-infrared fluorescence (NIRF) imaging is a new imaging technique that is used to visualize lymphatic vessels in humans. It has a high spatial and temporal resolution, allowing real-time visualization of lymphatic flow. METHODS AND RESULTS:The current study investigated the intra- and inter-individual va...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2016.0061
更新日期:2017-09-01 00:00:00
abstract:: Background: Lymphedema may impact patients' health-related quality of life (HRQoL). The purpose of this study was to evaluate HRQoL after two different treatments to the 12-month follow-up point. Methods and Results: Study part...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2018.0065
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Lymphedema leads to adipose tissue deposition. Water-fat magnetic resonance imaging (MRI) can quantify and localize fat and water. The presence of excess fat and excess water/muscle in the subfascial compartment of the lymphedematous limb has not been investigated before. The aim of this study was to investi...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0042
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Lymph is pumped through the collecting lymphatic vessels by both intrinsic and extrinsic forces, propelling it downstream back into circulation. The intrinsic lymph pump relies on the spontaneous contraction of lymphatic muscles to generate the force of pumping lymph (P(lp)). However, the association between...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2014.0015
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Lymphedema of limbs affects a large mass of tissues. Pathological changes develop in skin and subcutaneous tissue. Bacterial retention in edema fluid is followed by chronic inflammatory reaction. The question arises whether the chronic processes affecting a large mass of limb tissues are reflected in the ser...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0003
更新日期:2017-09-01 00:00:00
abstract:: Background: The Lymphedema Functioning, Disability, and Health questionnaire for Upper Limb Lymphedema (Lymph-ICF-UL) is a health-related quality-of-life questionnaire for patients with breast cancer-related lymphedema. Previous testing of this questionnaire showed very go...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2019.0073
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Lymphangiomatosis is a rare disorder of the lymphatic system that can impact the dermis, soft tissue, bone, and viscera and can be characterized by lymphangiomas, swelling, and chylous discharge. Whether disordered lymphangiogenesis in lymphangiomatosis affects the function and anatomy of the entire systemic...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2015.0013
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The aim of this prospective controlled study was to assess the efficacy of two different combination treatment modalities of lymphedema (LE). Manual lymphatic drainage (MLD) and compression bandage combination (complex decongestive therapy) have been compared with intermittent pneumatic compression (IPC) plu...
journal_title:Lymphatic research and biology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/lrb.2012.0002
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Bioimpedance spectroscopy (BIS) is commonly used in the assessment and monitoring of lymphedema. This study investigated electrodes as a source of variability that could impact the accuracy of BIS in the clinic and determined if Ag/AgCl electrocardiograph (ECG) electrodes could be used as an alternative to i...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2018.0002
更新日期:2019-02-01 00:00:00
abstract:: Background: Conservative nonsurgical treatment has traditionally been applied to lymphedema. Early surgical procedures were invasive and disfiguring and their long-term success was often limited. In contrast, contemporary surgical techniques are much less invasive and have...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2018.0038
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Primary idiopathic lymphedema is an uncommon condition that typically affects the lower extremities. Patients have a malformed lymphatic system that causes subcutaneous fluid and adipose deposition. Rarely, the disease also has been described in the upper extremities. The purpose of this study was to investi...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0085
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:This study sought to evaluate the effect of elastic compression, functional compressive bandaging, and kinesiotherapy on blood flow of the upper limb with lymphedema secondary to the treatment of breast cancer. METHODS:This was a randomized blind crossover clinical trial with a washout period of 7 days betwe...
journal_title:Lymphatic research and biology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/lrb.2016.0022
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Surgical manipulations of the axilla may cause a condition known as Axillary Web Syndrome (AWS). The systems compromised and the sequence of events leading to this syndrome remains unknown. This study evaluated clinical, surgical, and vascular factors associated with onset and duration of AWS after breast ca...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0037
更新日期:2018-06-01 00:00:00