Abstract:
:Cancer is one of the major growing public health problems making the development of new anti-cancer treatment strategies still compulsory. Conventionally used chemotherapies are quite often associated with severe side effects. One reason is limited cell-permeability of the used drugs resulting in only poor overall bioavailability. During the last thirty years, cell-penetrating peptides (CPPs) have extensively been studied as efficient vehicles for several classes of cargos, and the development of novel therapeutic applications including CPPs has gained a major role in current cancer research. This review summarizes recent trends in CPP-mediated cargo delivery with a future impact on anti-cancer therapy.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Klimpel A,Lützenburg T,Neundorf Idoi
10.1016/j.coph.2019.01.003subject
Has Abstractpub_date
2019-08-01 00:00:00pages
8-13eissn
1471-4892issn
1471-4973pii
S1471-4892(18)30085-7journal_volume
47pub_type
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