Crystal-confined freestanding ionic liquids for reconfigurable and repairable electronics.

abstract：:Chloroplasts communicate information by signalling to nuclei during acclimation to fluctuating light. Several potential operating signals originating from chloroplasts have been proposed, but none have been shown to move to nuclei to modulate gene expression. One proposed signal is hydrogen peroxide (H2O2) produced by...

journal_title：Nature communications

authors： Exposito-Rodriguez M,Laissue PP,Yvon-Durocher G,Smirnoff N,Mullineaux PM

更新日期：2017-06-29 00:00:00

abstract：:DNA strands of well-defined sequence are valuable in synthetic biology and nanostructure assembly. Drawing inspiration from solid-phase synthesis, here we describe a DNA assembly method that uses time, or order of addition, as a parameter to define structural complexity. DNA building blocks are sequentially added with...

journal_title：Nature communications

authors： Hamblin GD,Rahbani JF,Sleiman HF

更新日期：2015-05-05 00:00:00

abstract：:Targeting of immunoglobulin E (IgE) represents an interesting approach for the treatment of allergic disorders. A high-affinity monoclonal anti-IgE antibody, ligelizumab, has recently been developed to overcome some of the limitations associated with the clinical use of the therapeutic anti-IgE antibody, omalizumab. H...

journal_title：Nature communications

authors： Gasser P,Tarchevskaya SS,Guntern P,Brigger D,Ruppli R,Zbären N,Kleinboelting S,Heusser C,Jardetzky TS,Eggel A

更新日期：2020-01-08 00:00:00

abstract：:Understanding the impact of rare variants is essential to understanding human health. We analyze rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced individuals from the UK Biobank and 1934 phenotypes (1821 overlapping with UK Biobank) in 21,866 members of the Healthy Nevada Project (HNP) coho...

journal_title：Nature communications

authors： Cirulli ET,White S,Read RW,Elhanan G,Metcalf WJ,Tanudjaja F,Fath DM,Sandoval E,Isaksson M,Schlauch KA,Grzymski JJ,Lu JT,Washington NL

更新日期：2020-01-28 00:00:00

abstract：:Both anti-PD1/PD-L1 therapy and oncolytic virotherapy have demonstrated promise, yet have exhibited efficacy in only a small fraction of cancer patients. Here we hypothesized that an oncolytic poxvirus would attract T cells into the tumour, and induce PD-L1 expression in cancer and immune cells, leading to more suscep...

journal_title：Nature communications

authors： Liu Z,Ravindranathan R,Kalinski P,Guo ZS,Bartlett DL

更新日期：2017-03-27 00:00:00

abstract：:Solid-state quantum acoustodynamic (QAD) systems provide a compact platform for quantum information storage and processing by coupling acoustic phonon sources with superconducting or spin qubits. The multi-mode composite high-overtone bulk acoustic wave resonator (HBAR) is a popular phonon source well suited for QAD. ...

journal_title：Nature communications

authors： Gokhale VJ,Downey BP,Katzer DS,Nepal N,Lang AC,Stroud RM,Meyer DJ

更新日期：2020-05-08 00:00:00

abstract：:The development of theories and methods devoted to the accurate calculation of the electronic quasi-particle states and levels of molecules, clusters and solids is of prime importance to interpret the experimental data. These quantum systems are often modelled by using the Born-Oppenheimer approximation where the coup...

journal_title：Nature communications

authors： Gali A,Demján T,Vörös M,Thiering G,Cannuccia E,Marini A

更新日期：2016-04-22 00:00:00

abstract：:The ability to detect and deal with errors when manipulating quantum systems is a fundamental requirement for fault-tolerant quantum computing. Unlike classical bits that are subject to only digital bit-flip errors, quantum bits are susceptible to a much larger spectrum of errors, for which any complete quantum error-...

journal_title：Nature communications

authors： Córcoles AD,Magesan E,Srinivasan SJ,Cross AW,Steffen M,Gambetta JM,Chow JM

更新日期：2015-04-29 00:00:00

abstract：:Spectral domain optical coherence tomography (OCT) is a widely employed, minimally invasive bio-medical imaging technique, which requires a broadband light source, typically implemented by super-luminescent diodes. Recent advances in soliton based photonic integrated frequency combs (soliton microcombs) have enabled t...

journal_title：Nature communications

authors： Marchand PJ,Riemensberger J,Skehan JC,Ho JJ,Pfeiffer MHP,Liu J,Hauger C,Lasser T,Kippenberg TJ

更新日期：2021-01-18 00:00:00

abstract：:Neural computation relies on the integration of synaptic inputs across a neuron's dendritic arbour. However, it is far from understood how different cell types tune this process to establish cell-type specific computations. Here, using two-photon imaging of dendritic Ca2+ signals, electrical recordings of somatic volt...

journal_title：Nature communications

authors： Ran Y,Huang Z,Baden T,Schubert T,Baayen H,Berens P,Franke K,Euler T

更新日期：2020-04-30 00:00:00

abstract：:We characterized the population-level neural coding of ensemble representations in visual working memory from human electroencephalography. Ensemble representations provide a unique opportunity to investigate structured representations of working memory because the visual system encodes high-order summary statistics a...

journal_title：Nature communications

authors： Oh BI,Kim YJ,Kang MS

更新日期：2019-12-11 00:00:00

abstract：:To learn, obtain reward and survive, humans and other animals must monitor, approach and act on objects that are associated with variable or unknown rewards. However, the neuronal mechanisms that mediate behaviours aimed at uncertain objects are poorly understood. Here we demonstrate that a set of neurons in an intern...

journal_title：Nature communications

authors： White JK,Monosov IE

更新日期：2016-09-14 00:00:00

abstract：:The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions to systematically prioritize the most likely causal genes at associated loci, highlight enrich...

journal_title：Nature communications

authors： Pers TH,Karjalainen JM,Chan Y,Westra HJ,Wood AR,Yang J,Lui JC,Vedantam S,Gustafsson S,Esko T,Frayling T,Speliotes EK,Genetic Investigation of ANthropometric Traits (GIANT) Consortium.,Boehnke M,Raychaudhuri S,Fehrmann RS,

更新日期：2015-01-19 00:00:00

abstract：:The general paradigm is that monocytes are recruited to sites of inflammation and terminally differentiate into macrophages. There has been no demonstration of proliferation of peripherally-derived inflammatory macrophages under physiological conditions. Here we show that proliferation of both bone marrow-derived infl...

journal_title：Nature communications

authors： Davies LC,Rosas M,Jenkins SJ,Liao CT,Scurr MJ,Brombacher F,Fraser DJ,Allen JE,Jones SA,Taylor PR

更新日期：2013-01-01 00:00:00

abstract：:The incidence of non-alcoholic fatty liver disease (NAFLD) increases with age. Cellular senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of proinflammatory cytokines and mitochondrial dysfunction. Senescent cells contribute to age-related tissue degeneration. Here we show that...

journal_title：Nature communications

authors： Ogrodnik M,Miwa S,Tchkonia T,Tiniakos D,Wilson CL,Lahat A,Day CP,Burt A,Palmer A,Anstee QM,Grellscheid SN,Hoeijmakers JHJ,Barnhoorn S,Mann DA,Bird TG,Vermeij WP,Kirkland JL,Passos JF,von Zglinicki T,Jurk D

更新日期：2017-06-13 00:00:00

abstract：:The plasma membrane is uniquely enriched in phosphatidylserine (PtdSer). This anionic phospholipid is restricted almost exclusively to the inner leaflet of the plasmalemma. Because of their high density, the headgroups of anionic lipids experience electrostatic repulsion that, being exerted asymmetrically, is predicte...

journal_title：Nature communications

authors： Hirama T,Lu SM,Kay JG,Maekawa M,Kozlov MM,Grinstein S,Fairn GD

更新日期：2017-11-09 00:00:00

abstract：:There is increasing evidence from genome-wide association studies for a strong inherited genetic basis of susceptibility to acute lymphoblastic leukaemia (ALL) in children, yet the effects of protein-coding variants on ALL risk have not been systematically evaluated. Here we show a missense variant in CDKN2A associate...

journal_title：Nature communications

authors： Xu H,Zhang H,Yang W,Yadav R,Morrison AC,Qian M,Devidas M,Liu Y,Perez-Andreu V,Zhao X,Gastier-Foster JM,Lupo PJ,Neale G,Raetz E,Larsen E,Bowman WP,Carroll WL,Winick N,Williams R,Hansen T,Holm JC,Mardis E,Fulton

更新日期：2015-06-24 00:00:00

abstract：:The ubiquitous SAR11 and Prochlorococcus bacteria manage to maintain a sufficient supply of phosphate in phosphate-poor surface waters of the North Atlantic subtropical gyre. Furthermore, it seems that their phosphate uptake may counter-intuitively be lower in more productive tropical waters, as if their cellular dema...

journal_title：Nature communications

authors： Zubkov MV,Martin AP,Hartmann M,Grob C,Scanlan DJ

更新日期：2015-07-22 00:00:00

abstract：:The early diversification of animals (∼ 630 Ma), and their development into both motile and macroscopic forms (∼ 575-565 Ma), has been linked to stepwise increases in the oxygenation of Earth's surface environment. However, establishing such a linkage between oxygen and evolution for the later Cambrian 'explosion' (54...

journal_title：Nature communications

authors： Chen X,Ling HF,Vance D,Shields-Zhou GA,Zhu M,Poulton SW,Och LM,Jiang SY,Li D,Cremonese L,Archer C

更新日期：2015-05-18 00:00:00

abstract：:Cancer persister cells tolerate anticancer drugs and serve as the founders of acquired resistance and cancer relapse. Here we show that a subpopulation of BRAFV600 mutant melanoma cells that tolerates exposure to BRAF and MEK inhibitors undergoes a reversible remodelling of mRNA translation that evolves in parallel wi...

journal_title：Nature communications

authors： Shen S,Faouzi S,Bastide A,Martineau S,Malka-Mahieu H,Fu Y,Sun X,Mateus C,Routier E,Roy S,Desaubry L,André F,Eggermont A,David A,Scoazec JY,Vagner S,Robert C

更新日期：2019-12-16 00:00:00

abstract：:Human activities are transforming grassland biomass via changing climate, elemental nutrients, and herbivory. Theory predicts that food-limited herbivores will consume any additional biomass stimulated by nutrient inputs ('consumer-controlled'). Alternatively, nutrient supply is predicted to increase biomass where her...

journal_title：Nature communications

authors： Borer ET,Harpole WS,Adler PB,Arnillas CA,Bugalho MN,Cadotte MW,Caldeira MC,Campana S,Dickman CR,Dickson TL,Donohue I,Eskelinen A,Firn JL,Graff P,Gruner DS,Heckman RW,Koltz AM,Komatsu KJ,Lannes LS,MacDougall AS,Mar

更新日期：2020-11-27 00:00:00

abstract：:Anthropogenic methane emissions from China are likely greater than in any other country in the world. The largest fraction of China's anthropogenic emissions is attributable to coal mining, but these emissions may be changing; China enacted a suite of regulations for coal mine methane (CMM) drainage and utilization th...

journal_title：Nature communications

authors： Miller SM,Michalak AM,Detmers RG,Hasekamp OP,Bruhwiler LMP,Schwietzke S

更新日期：2019-01-29 00:00:00

abstract：:With damage tolerance rivalling advanced engineering alloys and thermoplastic forming capabilities analogous to conventional plastics, metallic glasses are emerging as a modern engineering material. Here, we take advantage of their unique electrical and rheological properties along with the classic Lorentz force conce...

journal_title：Nature communications

authors： Kaltenboeck G,Demetriou MD,Roberts S,Johnson WL

更新日期：2016-02-08 00:00:00

abstract：:Niobium diselenide has long served as a prototype of two-dimensional charge ordering, believed to arise from an instability of the electronic structure analogous to the one-dimensional Peierls mechanism. Despite this, various anomalous properties have recently been identified experimentally, which cannot be explained ...

journal_title：Nature communications

authors： Flicker F,van Wezel J

更新日期：2015-05-07 00:00:00

abstract：:Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS meta-analysis of total-body lean mass (TB-LM) and total-body less head bone mineral density (TBLH...

journal_title：Nature communications

authors： Medina-Gomez C,Kemp JP,Dimou NL,Kreiner E,Chesi A,Zemel BS,Bønnelykke K,Boer CG,Ahluwalia TS,Bisgaard H,Evangelou E,Heppe DHM,Bonewald LF,Gorski JP,Ghanbari M,Demissie S,Duque G,Maurano MT,Kiel DP,Hsu YH,C J van d

更新日期：2017-07-25 00:00:00

abstract：:Surface charge density is the key factor for developing high performance triboelectric nanogenerators (TENG). The previously invented charge excitation TENG provides a most efficient way to achieve maximum charge output of a TENG device. Herein, criteria to quantitatively evaluate the contact efficiency and air breakd...

journal_title：Nature communications

authors： Liu Y,Liu W,Wang Z,He W,Tang Q,Xi Y,Wang X,Guo H,Hu C

更新日期：2020-03-27 00:00:00

abstract：:To fully exploit the microbial genome resources, a high-throughput experimental platform is needed to associate genes with phenotypes at the genome level. We present here a novel method that enables investigation of the cellular consequences of repressing individual transcripts based on the CRISPR interference (CRISPR...

journal_title：Nature communications

authors： Wang T,Guan C,Guo J,Liu B,Wu Y,Xie Z,Zhang C,Xing XH

更新日期：2018-06-26 00:00:00

abstract：:Real-time imaging of moving organs and tissues at microscopic resolutions represents a major challenge in studying the complex biology of live animals. Here we present a technique based on a novel stabilizer setup combined with a gating acquisition algorithm for the imaging of a beating murine heart at the single-cell...

journal_title：Nature communications

authors： Lee S,Vinegoni C,Feruglio PF,Fexon L,Gorbatov R,Pivoravov M,Sbarbati A,Nahrendorf M,Weissleder R

更新日期：2012-01-01 00:00:00

abstract：:Supersymmetry is a conjectured symmetry between bosons and fermions aiming at solving fundamental questions in string and quantum field theory. Its subsequent application to quantum mechanics led to a ground-breaking analysis and design machinery, later fruitfully extrapolated to photonics. In all cases, the algebraic...

journal_title：Nature communications

authors： García-Meca C,Ortiz AM,Sáez RL

更新日期：2020-02-10 00:00:00

abstract：:Our ability to uncover complex network structure and dynamics from data is fundamental to understanding and controlling collective dynamics in complex systems. Despite recent progress in this area, reconstructing networks with stochastic dynamical processes from limited time series remains to be an outstanding problem...

journal_title：Nature communications

authors： Shen Z,Wang WX,Fan Y,Di Z,Lai YC

更新日期：2014-07-11 00:00:00