CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer.

abstract：:The high theoretical capacity and low discharge potential of silicon have attracted much attention on Si-based anodes. Herein, hollow porous SiO2 nanocubes have been prepared via a two-step hard-template process and evaluated as electrode materials for lithium-ion batteries. The hollow porous SiO2 nanocubes exhibited ...

journal_title：Scientific reports

authors： Yan N,Wang F,Zhong H,Li Y,Wang Y,Hu L,Chen Q

更新日期：2013-01-01 00:00:00

abstract：:Although the cause of Alzheimer's disease (AD) is unknown, glial-induced neuroinflammation is an early symptom. Familial AD is caused by increases in amyloid-beta (Aβ) peptide, particularly soluble oligomeric (oAβ), considered a proximal neurotoxin and neuroinflammatory stimuli. APOE4, a naturally occurring genotype o...

journal_title：Scientific reports

authors： Ghura S,Tai L,Zhao M,Collins N,Che CT,Warpeha KM,LaDu MJ

更新日期：2016-07-07 00:00:00

abstract：:The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically, we use sgRNA-mediated CRISPR/Cas9 to target the open reading fr...

journal_title：Scientific reports

authors： You Y,Ramachandra SG,Jin T

更新日期：2020-09-08 00:00:00

abstract：:A new species of fossil conifer wood, Podocarpoxylon donghuaiense sp. nov., is described from the late Eocene of Nadu Formation in Baise Basin of the Guangxi Province, South China. This fossil wood is characterized by distinct growth rings, circular to oval tracheids in cross section, 1-2-seriate opposite pits on radi...

journal_title：Scientific reports

authors： Li L,Jin JH,Quan C,Oskolski AA

更新日期：2016-08-30 00:00:00

abstract：:Prostaglandins (PGs) are hormone-like mediators in many physiological and pathological processes that are present in all vertebrates, in some terrestrial and aquatic invertebrates, and have also been identified in some macroalgae. They have recently been reported also in marine microalgae but their role as chemical me...

journal_title：Scientific reports

authors： Di Dato V,Barbarinaldi R,Amato A,Di Costanzo F,Fontanarosa C,Perna A,Amoresano A,Esposito F,Cutignano A,Ianora A,Romano G

更新日期：2020-03-25 00:00:00

abstract：:The therapeutic potential of targeting CD4+Foxp3+ regulatory T cells (Tregs) remains controversial under the condition of neuroinflammation. This study aims to explore the neuroprotective role of Tregs in optic nerve ischemia (ONI) and evaluate the therapeutic strategy of Tregs transfer with a focus on targeting the m...

journal_title：Scientific reports

authors： Chen G,Tang L,Wei W,Li Z,Li Y,Duan X,Chen H

更新日期：2016-11-25 00:00:00

abstract：:Dysfunction of energy metabolism is involved in inflammatory bowel disease (IBD). This study was designed to investigate the potential of astragaloside IV (ASIV), an active ingredient of Radix Astragalus, to ameliorate colonic mucosal injury, with focusing on the implication of energy restoration in the underlying mec...

journal_title：Scientific reports

authors： Jiang XG,Sun K,Liu YY,Yan L,Wang MX,Fan JY,Mu HN,Li C,Chen YY,Wang CS,Han JY

更新日期：2017-02-02 00:00:00

abstract：:This study was aimed to assess the relationship of intraocular forward scattering, corneal backward scattering, and corneal higher-order aberrations (HOAs) with corrected distance visual acuity (CDVA) in eyes with granular corneal dystrophy (GCD). We retrospectively examined forty two eyes of 42 consecutive patients w...

journal_title：Scientific reports

authors： Kamiya K,Kobashi H,Igarashi A,Shoji N,Shimizu K

更新日期：2016-04-18 00:00:00

abstract：:Compromised gut health and dysbiosis in people with heart failure has received a great deal of attention over the last decade. Whether dogs with heart failure have a similar dysbiosis pattern to what is described in people is currently unknown. We hypothesised that dogs with congestive heart failure have quantifiable ...

journal_title：Scientific reports

authors： Seo J,Matthewman L,Xia D,Wilshaw J,Chang YM,Connolly DJ

更新日期：2020-08-13 00:00:00

abstract：:Aging is accompanied by a decline in memory and other brain functions. Physical exercise may mitigate this decline through the modulation of factors participating in the crosstalk between skeletal muscle and the brain, such as neurotrophins and oxidative stress parameters. We aimed to determine whether long term exerc...

journal_title：Scientific reports

authors： De la Rosa A,Solana E,Corpas R,Bartrés-Faz D,Pallàs M,Vina J,Sanfeliu C,Gomez-Cabrera MC

更新日期：2019-03-04 00:00:00

abstract：:Colorectal cancer (CRC) is a common complex disease caused by the combination of genetic variants and environmental factors. Genome-wide association studies (GWAS) have been performed and reported some novel CRC susceptibility variants. However, the potential genetic mechanisms for newly identified CRC susceptibility ...

journal_title：Scientific reports

authors： Lu X,Cao M,Han S,Yang Y,Zhou J

更新日期：2016-05-05 00:00:00

abstract：:We demonstrated tailored plasmon-induced transparency (PIT) in a metal (Au)-insulator (SiO2)-metal (Ag) (MIM) structure, where the Fano interference between the MIM waveguide mode and the surface plasmon polariton (SPP) resonance mode induced a transparency window in an otherwise opaque wavenumber (k) region. A series...

journal_title：Scientific reports

authors： Matsunaga K,Hirai Y,Neo Y,Matsumoto T,Tomita M

更新日期：2017-12-19 00:00:00

abstract：:Although copy number variation (CNV) and presence-absence variation (PAV) have been discovered in selected gene families in most crop species, the global prevalence of these polymorphisms in most complex genomes is still unclear and their influence on quantitatively inherited agronomic traits is still largely unknown....

journal_title：Scientific reports

authors： Gabur I,Chawla HS,Lopisso DT,von Tiedemann A,Snowdon RJ,Obermeier C

更新日期：2020-03-05 00:00:00

abstract：:Oviposition site-selection in insects is mediated through innate recognition templates (IRTs) tuned to specific chemical cues. These cues aid gravid insects in choosing suitable oviposition sites and may even enhance the fitness of their offspring by warding off predators and parasitoids. However, studies on the evolu...

journal_title：Scientific reports

authors： Damodaram KJ,Kempraj V,Aurade RM,Rajasekhar SB,Venkataramanappa RK,Nandagopal B,Verghese A

更新日期：2014-12-15 00:00:00

abstract：:Satellite aerosol optical depth (AOD) is widely used to estimate particulate matter with aerodynamic diameter ≤2.5 µm (PM2.5) mass concentrations. Polar orbiting satellite retrieval 1-2 times each day is frequently affected by cloud, snow cover or misclassification of heavy pollution. Novel methods are therefore requi...

journal_title：Scientific reports

authors： Fu D,Xia X,Wang J,Zhang X,Li X,Liu J

更新日期：2018-07-05 00:00:00

abstract：:Symbiodinium is best-known as the photosynthetic symbiont of corals, but some clades are symbiotic in other organisms or include free-living forms. Identifying similarities and differences among these clades can help us understand their relationship with corals, and thereby inform on measures to manage coral reefs in ...

journal_title：Scientific reports

authors： González-Pech RA,Ragan MA,Chan CX

更新日期：2017-11-03 00:00:00

abstract：:The present study investigated the effect of aldehyde dehydrogenase2 (ALDH2) rs671 polymorphism and alcohol consumption on the severity of primary open-angle glaucoma (POAG). The questionnaire for alcohol consumption pattern and targeted genotyping for ALDH2 rs671 polymorphism was performed from 445 Korean POAG patien...

journal_title：Scientific reports

authors： Han YS,Kim YW,Kim YJ,Park KH,Jeoung JW

更新日期：2020-10-15 00:00:00

abstract：:The glycocalyx regulates the interaction of mammalian cells with extracellular molecules, such as cytokines. However, it is unknown to which extend the glycocalyx of distinct cancer cells control the binding and uptake of nanoparticles. In the present study, exome sequencing data of cancer patients and analysis of dis...

journal_title：Scientific reports

authors： von Palubitzki L,Wang Y,Hoffmann S,Vidal-Y-Sy S,Zobiak B,Failla AV,Schmage P,John A,Osorio-Madrazo A,Bauer AT,Schneider SW,Goycoolea FM,Gorzelanny C

更新日期：2020-12-31 00:00:00

abstract：:Stemborers (Busseola fusca, Sesamia calamistis and Chilo partellus), the fall armyworm (Spodoptera frugiperda) and associated parasitoids constitute an interacting system in maize fields in Kenya. This work aims at developing and evaluating models that represent the evolution of those interactions by applying system t...

journal_title：Scientific reports

authors： Sokame BM,Tonnang HEZ,Subramanian S,Bruce AY,Dubois T,Ekesi S,Calatayud PA

更新日期：2021-01-14 00:00:00

abstract：:A better understanding of the structure and extent of genetic variability in a breeding population of a crop is essential for translating genetic diversity to genetic gain. We assessed the nature and pattern of genetic variability and differentiation in a panel of 100 winged-yam (Dioscorea alata) accessions using 24 p...

journal_title：Scientific reports

authors： Agre P,Asibe F,Darkwa K,Edemodu A,Bauchet G,Asiedu R,Adebola P,Asfaw A

更新日期：2019-12-03 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a common liver disease. Previous studies on the association between Helicobacter pylori (HP) infection and NAFLD are inconsistent. Our study was aimed to find out the relationship between HP infection and NAFLD. We performed a large cross-sectional study in northern Chinese...

journal_title：Scientific reports

authors： Jiang T,Chen X,Xia C,Liu H,Yan H,Wang G,Wu Z

更新日期：2019-03-19 00:00:00

abstract：:Assistive wearable soft robotic systems have recently made a surge in the field of biomedical robotics, as soft materials allow safe and transparent interactions between the users and devices. A recent interest in the field of soft pneumatic actuators (SPAs) has been the introduction of a new class of actuators called...

journal_title：Scientific reports

authors： Nguyen PH,Zhang W

更新日期：2020-06-15 00:00:00

abstract：:Ionizing radiation (IR)-induced intestinal damage is characterized by a loss of intestinal crypt cells, intestinal barrier disruption and translocation of intestinal microflora resulting in sepsis-mediated lethality. We have shown that mice lacking C/EBPδ display IR-induced intestinal and hematopoietic injury and leth...

journal_title：Scientific reports

authors： Banerjee S,Fu Q,Shah SK,Melnyk SB,Sterneck E,Hauer-Jensen M,Pawar SA

更新日期：2019-09-27 00:00:00

abstract：:Insulin resistance is common among children with overweight and obesity. However, knowledge about glucose fluctuations in these children is scarce. This study aims to evaluate glycaemic profiles in children with overweight and obesity in free-living conditions, and to examine the association between glycaemic profiles...

journal_title：Scientific reports

authors： Rijks J,Karnebeek K,van Dijk JW,Dorenbos E,Gerver WJ,Stouthart P,Plat J,Vreugdenhil A

更新日期：2016-08-18 00:00:00

abstract：:Corticofugal fibers target the subthalamic nucleus (STN), a component nucleus of the basal ganglia, in addition to the striatum, their main input. The cortico-subthalamic, or hyperdirect, pathway, is thought to supplement the cortico-striatal pathways in order to interrupt/change planned actions. To explore the previo...

journal_title：Scientific reports

authors： Froux L,Le Bon-Jego M,Miguelez C,Normand E,Morin S,Fioramonti S,Barresi M,Frick A,Baufreton J,Taupignon A

更新日期：2018-06-11 00:00:00

abstract：:In this report, we propose and demonstrate an air-mode photonic crystal ring resonator (PhCRR) on silicon-on-insulator platform. Air mode is utilized to confine the optical field into photonic crystal (PhC) air holes, which is confirmed by the three-dimensional finite-difference time-domain simulation. PhCRR structure...

journal_title：Scientific reports

authors： Gao G,Zhang Y,Zhang H,Wang Y,Huang Q,Xia J

更新日期：2016-01-28 00:00:00

abstract：:Biochar can influence native soil organic carbon (SOC) mineralisation through "priming effects". However, the long-term direction, persistence and extent of SOC priming by biochar remain uncertain. Using natural (13)C abundance and under controlled laboratory conditions, we show that biochar-stimulated SOC mineralisat...

journal_title：Scientific reports

authors： Singh BP,Cowie AL

更新日期：2014-01-21 00:00:00

abstract：:RNaseIII proteins are dsRNA-specific endonucleases involved in many important biological processes, such as small RNA processing and maturation in eukaryotes. Various small RNAs have been identified in a protozoan parasite Entamoeba histolytica. EhRNaseIII is the only RNaseIII endonuclease domain (RIIID)-containing pr...

journal_title：Scientific reports

authors： Yu X,Li X,Zheng L,Ma J,Gan J

更新日期：2017-03-20 00:00:00

abstract：:Three-dimensional anodic alumina templates (3D-AAO) are an astonishing framework with open highly ordered three-dimensional skeleton structures. Since these templates are architecturally different from conventional solids or porous templates, they teem with opportunities for engineering thermal properties. By establis...

journal_title：Scientific reports

authors： Abad B,Maiz J,Ruiz-Clavijo A,Caballero-Calero O,Martin-Gonzalez M

更新日期：2016-12-09 00:00:00

abstract：:Overuse of antibiotics has caused serious problems, such as appearance of super bacteria, whose accumulation in the human body through the food chain is a concern. Kanamycin is a common antibiotic used to treat diverse infections; however, residual kanamycin can cause many side effects in humans. Thus, development of ...

journal_title：Scientific reports

authors： Ha NR,Jung IP,La IJ,Jung HS,Yoon MY

更新日期：2017-01-05 00:00:00