miR-124 promotes neural differentiation in mouse bulge stem cells by repressing Ptbp1 and Sox9.

abstract：:Electrical stimulation (ES) has been shown to improve some of impairments after spinal cord injury (SCI), but the underlying mechanisms remain unclear. The Wnt signaling pathways and the endocannabinoid system appear to be modulated in response to SCI. This study aimed to investigate the effect of ES therapy on the ac...

journal_title：Journal of cellular physiology

authors： Ghorbani M,Shahabi P,Karimi P,Soltani-Zangbar H,Morshedi M,Bani S,Jafarzadehgharehziaaddin M,Sadeghzadeh-Oskouei B,Ahmadalipour A

更新日期：2020-12-01 00:00:00

abstract：:Activation of the receptor tyrosine kinase c-kit by the kit-ligand, also known as stem cell factor (SCF), is essential to melanocyte and germ cell development and during the early stages of hematopoiesis. Deregulated expression of c-kit has been reported in malignancies affecting these lineages, i.e., myeloid leukemia...

journal_title：Journal of cellular physiology

authors： Bellone G,Silvestri S,Artusio E,Tibaudi D,Turletti A,Geuna M,Giachino C,Valente G,Emanuelli G,Rodeck U

更新日期：1997-07-01 00:00:00

abstract：:Primary porcine bronchial epithelial cells (PBECs) are an ideal model to study the molecular and pathogenic mechanisms of various porcine respiratory pathogens. However, the short lifespan of primary PBECs greatly limit their application. Here, we isolated and cultured primary PBECs and established immortalized PBECs ...

journal_title：Journal of cellular physiology

authors： Xie X,Gan Y,Pang M,Shao G,Zhang L,Liu B,Xu Q,Wang H,Feng Y,Yu Y,Chen R,Wu M,Zhang Z,Hua L,Xiong Q,Liu M,Feng Z

更新日期：2018-12-01 00:00:00

abstract：:To test the hypothesis that football training would be accompanied by physiological adaptations and hormonal changes, we analyzed the effects of a whole football season on physical fitness and hormonal concentrations in youth football players. Male football players (n = 29, age 16.51 ± 0.7 years) in a regional profess...

journal_title：Journal of cellular physiology

authors： Muscella A,Vetrugno C,Spedicato M,Stefàno E,Marsigliante S

更新日期：2019-11-01 00:00:00

abstract：:Pancreatic cancer is a common malignant digestive disease. Epidemiological and clinical studies have demonstrated that pancreatic cancer is closely related to diabetes mellitus. Diabetic patients are more likely to develop pancreatic cancer, which is linked with poor outcomes. Pancreatic cancer is complicated with abn...

journal_title：Journal of cellular physiology

authors： Ma X,Cui Z,Du Z,Lin H

更新日期：2020-09-01 00:00:00

abstract：:At the initial stage of cell-cell contact of epithelial cells, primordial spot-like junctions are formed at the tips of thin cellular protrusions radiating from adjacent cells, where E-cadherin and ZO-1 are precisely coconcentrated (Yonemura et al., 1995, J. Cell Sci. 108:127-142). In fully polarized epithelial cells,...

journal_title：Journal of cellular physiology

authors： Ando-Akatsuka Y,Yonemura S,Itoh M,Furuse M,Tsukita S

更新日期：1999-05-01 00:00:00

abstract：:Hyperammonaemia and hyperethanolaemia are thought to be driving factors behind skeletal muscle myopathy in liver disease, that is, cirrhosis. Despite this, the singular and combined impacts of ethanol- and ammonia-induced protein catabolism are poorly defined. As such, we aimed to dissect out the effects of ammonia an...

journal_title：Journal of cellular physiology

authors： Crossland H,Smith K,Atherton PJ,Wilkinson DJ

更新日期：2018-12-01 00:00:00

abstract：:We compared the effects of 95% O2 (hyperoxia) alone, endotoxin (20 ng/ml) alone, and 95% O2 plus endotoxin on the release of lactate dehydrogenase (LDH), uptake of 5-hydroxytryptamine (5-HT), and antioxidant enzyme activities in porcine pulmonary arterial and aortic endothelial cells in monolayer culture. Hyperoxia in...

journal_title：Journal of cellular physiology

authors： Block ER,Patel JM,Sheridan NP

更新日期：1985-02-01 00:00:00

abstract：:Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken int...

journal_title：Journal of cellular physiology

authors： Caligiuri I,Rizzolio F,Boffo S,Giordano A,Toffoli G

更新日期：2012-08-01 00:00:00

abstract：:alpha-Thrombin, bradykinin, and histamine are endogenous mediators that increase endothelial permeability. We examined the mechanism by which these three vasoactive mediators could alter permeability to albumin of human umbilical vein endothelial cells (HUVEC). HUVEC were grown to confluence on Transwell membranes and...

journal_title：Journal of cellular physiology

authors： Ehringer WD,Edwards MJ,Miller FN

更新日期：1996-06-01 00:00:00

abstract：:Atherosclerosis is one of the leading causes of morbidity and mortality, mainly due to the immune response triggered by the recruitment of monocytes/macrophages in the artery wall. Accumulating evidence have shown that matrix stiffness and oxidized low-density lipoproteins (ox-LDL) play important roles in atherosclero...

journal_title：Journal of cellular physiology

authors： Li J,Wang S,Li Y,Zhang N,Gribskov M,Zhang X,Lin M,Shao D,Zhang C,Dai L,Qin C,Duan X,Li J,Xu F,Yang H

更新日期：2020-09-01 00:00:00

abstract：:It was the goal of this study to determine whether during long-term quiescence WI-38 cells gradually lose labile components which then need to be resynthesized before a stimulated cell can progress through G-1 and enter S. The metabolic and molecular status of WI-38 cells was systematically analyzed as they entered an...

journal_title：Journal of cellular physiology

authors： Owen TA,Carter R,Whitman MM,Soprano DR,Soprano KJ

更新日期：1990-01-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) promotes the regeneration of periodontal tissue. Since angiogenesis is important for tissue regeneration, investigating effect of BDNF on endothelial cell function may help to reveal its mechanism, whereby, BDNF promotes periodontal tissue regeneration. In this study, we examin...

journal_title：Journal of cellular physiology

authors： Matsuda S,Fujita T,Kajiya M,Takeda K,Shiba H,Kawaguchi H,Kurihara H

更新日期：2012-05-01 00:00:00

abstract：:The unique vascular supply of the retina, the ability to visualize the vasculature in vivo, and the ability to selectively express genes in the retina make the retina an ideal model system to study molecular mechanisms of angiogenesis. In addition, this area of investigation has great clinical significance, because re...

journal_title：Journal of cellular physiology

authors： Campochiaro PA

更新日期：2000-09-01 00:00:00

abstract：:The expression of a set of cell cycle dependent (CCD) genes (c-fos, c-myc, ornithine decarboxylase (ODC), and thymidine kinase (TK)) was comparatively studied in cultured arterial smooth muscle cells (SMC) during exit from quiescence and exponential proliferation. These genes, which were not expressed in quiescent SMC...

journal_title：Journal of cellular physiology

authors： Campan M,Desgranges C,Gadeau AP,Millet D,Belloc F

更新日期：1992-03-01 00:00:00

abstract：:MicroRNAs (miRNAs) is a small molecule (19-25 nucleotide) noncoding RNA that inhibits the expression of target messenger RNA (mRNA) at the posttranscriptional level as an endogenous regulator. There is an increasing evidence that miR-199a-3p has a significant effect on the development of multiple tumors. However, the ...

journal_title：Journal of cellular physiology

authors： Chen HP,Wen J,Tan SR,Kang LM,Zhu GC

更新日期：2019-12-01 00:00:00

abstract：:Plasminogen activator inhibitor-1 (PAI-1) is known as an inhibitor of fibrinolytic system. Previous studies suggest that PAI-1 is involved in the pathogenesis of osteoporosis induced by ovariectomy, diabetes, and glucocorticoid excess in mice. However, the roles of PAI-1 in early-stage osteogenic differentiation have ...

journal_title：Journal of cellular physiology

authors： Takafuji Y,Tatsumi K,Ishida M,Kawao N,Okada K,Matsuo O,Kaji H

更新日期：2019-06-01 00:00:00

abstract：:Thymosin β4 (Tβ4), a G-actin-sequestering secreted peptide, improves neurovascular remodeling and central nervous system plasticity, which leads to neurological recovery in many neurological diseases. Inflammatory response adjustment and tissue inflammation consequences from neurological injury are vital for neurologi...

journal_title：Journal of cellular physiology

authors： Shomali N,Baradaran B,Deljavanghodrati M,Akbari M,Hemmatzadeh M,Mohammadi H,Jang Y,Xu H,Sandoghchian Shotorbani S

更新日期：2020-04-01 00:00:00

abstract：:HCF-1 functions as a coactivator for herpes simplex virus VP16 and a number of mammalian transcription factors. Mature HCF-1 is composed of two subunits generated by proteolytic cleavage of a larger precursor at six centrally-located HCF(PRO) repeats. The resulting N- and C-terminal subunits remain tightly associated ...

journal_title：Journal of cellular physiology

authors： Mahajan SS,Johnson KM,Wilson AC

更新日期：2003-02-01 00:00:00

abstract：:Pyroptosis is a form of necrotic and inflammatory programmed cell death, which could be characterized by cell swelling, pore formation on plasma membranes, and release of proinflammatory cytokines (IL-1β and IL-18). The process of pyroptosis presents as dual effects: protecting multicellular organisms from microbial i...

journal_title：Journal of cellular physiology

authors： Lu F,Lan Z,Xin Z,He C,Guo Z,Xia X,Hu T

更新日期：2020-04-01 00:00:00

abstract：:In recent years, research on glioma immunotherapy have grown rapidly. However, the autoimmune-like side effects that are caused by blocking immunological checkpoints hinder their clinical application in gliomas currently. Galectin-9, a ligand for T-cell immunoglobulin mucin 3, has shed a new light on the treatment of ...

journal_title：Journal of cellular physiology

authors： Yuan F,Ming H,Wang Y,Yang Y,Yi L,Li T,Ma H,Tong L,Zhang L,Liu P,Li J,Lin Y,Yu S,Ren B,Yang X

更新日期：2020-05-01 00:00:00

abstract：:Construction of artificial organs and tissues by tissue engineering is strongly dependent on the availability of viable cells. For that reason, the viability and the physiological status of cells kept in culture must be evaluated before the cells can be used for clinical purposes. In this work, we determined the viabi...

journal_title：Journal of cellular physiology

authors： Alaminos M,Sanchez-Quevedo MC,Muñoz-Avila JI,García JM,Crespo PV,González-Andrades M,Campos A

更新日期：2007-06-01 00:00:00

abstract：:Vimentin-positive, desmin-negative cells were established in culture from the nodule and from apparently normal palmar aponeurosis of a patient with Dupuytren's disease and compared with normal human embryonic and adult fibroblasts or sarcomatous cells. Cells from the nodule display in vitro biological properties that...

journal_title：Journal of cellular physiology

authors： Azzarone B,Failly-Crepin C,Daya-Grosjean L,Chaponnier C,Gabbiani G

更新日期：1983-12-01 00:00:00

abstract：:We have previously identified two stimulatory activities affecting blood cell maturation in PHA-stimulated human lymphocytes conditioned medium (PHA-LyCM). One was granulocyte-macrophage colony stimulatory activity (GM-CSA), and the other was T lymphocyte growth stimulatory activity (TL-GSA) in suspension culture. In ...

journal_title：Journal of cellular physiology

authors： Wu AM

更新日期：1979-11-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) Rev protein facilitates the nuclear export of viral mRNA containing the Rev response element (RRE). Although several host proteins co-operating with Rev in viral RNA export have been reported, little is known about the innate host defense factors that Rev overcomes to me...

journal_title：Journal of cellular physiology

authors： Modem S,Reddy TR

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Surgical stress has been suggested to facilitate colon cancer growth and metastasis. However, the precise mechanisms by which surgical trauma promotes colon cancer progression remain poorly understood. METHODS:To unravel the mechanisms underlying surgery-induced colon cancer progression, a syngenic transpla...

journal_title：Journal of cellular physiology

authors： Sun Z,Du C,Xu P,Miao C

更新日期：2019-04-01 00:00:00

abstract：:Using the Madin Darby canine kidney (MDCK) cell "calcium switch," we have previously demonstrated that, as MDCK cells establish contact and ultimately form tight junctions, there are marked global and localized changes in intracellular calcium at the sites of cell-cell contact (Nigam et al., 1992, Proc. Natl. Acad. Sc...

journal_title：Journal of cellular physiology

authors： Stuart RO,Sun A,Panichas M,Hebert SC,Brenner BM,Nigam SK

更新日期：1994-06-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (BMSC) can ameliorate ischemic injury of various tissues. However, the molecular mechanisms involved remain to be clarified. In this study, we intend to investigate the effects of BMSC-derived conditioned medium (BMSC-CM) on hypoxia/reoxygenation (H/R)-induced injury of H9c2 myocardi...

journal_title：Journal of cellular physiology

authors： Li X,Xie X,Yu Z,Chen Y,Qu G,Yu H,Luo B,Lei Y,Li Y

更新日期：2019-08-01 00:00:00

abstract：:The effects of the glucose supply on growth and metabolism of an SP2/0 derived recombinant myeloma cell line were studied in chemostat culture during growth on IMDM medium at a fixed dilution rate of 0.032 h-1. Lowering of the feed medium glucose concentration from 25.0 to 1.4 mmol/L resulted in a decrease of steady-s...

journal_title：Journal of cellular physiology

authors： Meijer JJ,van Dijken JP

更新日期：1995-02-01 00:00:00

abstract：:We have previously shown that mitochondrial activity is an important regulator of myoblast differentiation, partly through processes targeting myogenin expression. Here, we investigated the possible involvement of c-myc in these processes. Inhibition of mitochondrial activity by chloramphenicol abrogated the decrease ...

journal_title：Journal of cellular physiology

authors： Seyer P,Grandemange S,Busson M,Carazo A,Gamaléri F,Pessemesse L,Casas F,Cabello G,Wrutniak-Cabello C

更新日期：2006-04-01 00:00:00