Retinal and choroidal neovascularization.

abstract：:While mesenchymal stem cells (MSCs) have been widely used to repair radiation-induced bone damage, the molecular mechanism underlying the effects of MSCs in the maintenance of bone homeostasis under radiation stress remains largely unknown. In this study, the role and mechanisms of R-spondin 1 (Rspo1)-leucine-rich rep...

journal_title：Journal of cellular physiology

authors： Chen X,Chen L,Tan J,Zhang L,Xia J,Cheng B,Zhang W

更新日期：2021-01-16 00:00:00

abstract：:Former studies have linked hepatocyte growth with liver fatty acid binding protein (L-FABP) of rat liver cytosol. In search for the roles of L-FABP in hepatocytes, we previously stably transfected rat L-FABP sense and antisense cDNAs into rat hepatoma HTC cells that do not contain L-FABP RNA or protein, thereby provid...

journal_title：Journal of cellular physiology

authors： Keler T,Sorof S

更新日期：1993-10-01 00:00:00

abstract：:The E5 protein of the bovine papillomavirus induces cellular transformation when transfected into NIH 3T3 cells, and the extent of focal transformation is enhanced by cotransfection with the epidermal growth factor (EGF) receptor (Martin et al., Cell 59:21-32, 1989). To determine whether E5 affects EGF:receptor intera...

journal_title：Journal of cellular physiology

authors： Waters CM,Overholser KA,Sorkin A,Carpenter G

更新日期：1992-08-01 00:00:00

abstract：:Cardiac hypertrophy (CH) has become a huge threat to human health. Recent years, long noncoding RNAs (lncRNAs) have been studied in human diseases, including CH. According to bioinformatics analysis, 10 lncRNAs possibly involved in the progression of CH were screened out. Among which, lncRNA SYNE1 antisense RNA 1 (SYN...

journal_title：Journal of cellular physiology

authors： Wang Y,Cao R,Yang W,Qi B

更新日期：2019-08-01 00:00:00

abstract：:Adhesion of calf lens epithelial cells to lens capsule, their natural basement membrane was found to be considerably more rapid than either to plastic or to type I or type IV collagen coated surfaces. No polarity of the basement membrane was observed as the cells were able to attach to either side of the anterior or p...

journal_title：Journal of cellular physiology

authors： Cammarata PR,Spiro RG

更新日期：1982-11-01 00:00:00

abstract：:BA10-IR transformed cells, obtained by treating Syrian hamster embryo fibroblasts (HEF) with 7-methylbenz(a)anthracene and cultivated for a long period, are highly tumorigenic and grow in suspension as aggregates (spheroids) (Levy et al., 1976). They also grow in attached form or as spheroids in serum-free (S-) synthe...

journal_title：Journal of cellular physiology

authors： Xin LW,Jullien P,Lawrence DA,Pironin M,Vigier P

更新日期：1987-05-01 00:00:00

abstract：:Endometriosis is a chronic gynecological inflammatory disorder in which immune system dysregulation is thought to play a role in its initiation and progression. Due to altered sex steroid receptor concentrations and other signaling defects, eutopic endometriotic tissues have an attenuated response to progesterone. Thi...

journal_title：Journal of cellular physiology

authors： Chowdhury I,Banerjee S,Driss A,Xu W,Mehrabi S,Nezhat C,Sidell N,Taylor RN,Thompson WE

更新日期：2019-05-01 00:00:00

abstract：:Circular RNAs (circRNAs) play critical roles in signal transduction during cell proliferation, differentiation, and apoptosis in a posttranscriptional manner. Recently, circRNAs have been proved to be a large class of animal RNAs with regulatory potency. However, whether circRNAs can respond to mechanical force (MF) a...

journal_title：Journal of cellular physiology

authors： Wang H,Feng C,Jin Y,Tan W,Wei F

更新日期：2019-07-01 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP) (107-139), in contrast to the N-terminal fragment PTHrP (1-36), has been shown to interact with the vascular endothelial growth factor (VEGF) system to modulate human osteoblast differentiation. In this study, we evaluated whether this interaction might affect human osteobla...

journal_title：Journal of cellular physiology

authors： Alonso V,de Gortázar AR,Ardura JA,Andrade-Zapata I,Alvarez-Arroyo MV,Esbrit P

更新日期：2008-12-01 00:00:00

abstract：:Skeletal muscle dysfunction contributes to exercise limitation in COPD. In this study cigarette smoke exposure was hypothesized to increase expression of the inflammatory cytokine, TNF-alpha, thereby suppressing PGC-1alpha, and hence affecting down stream molecules that regulate oxygen transport and muscle function. F...

journal_title：Journal of cellular physiology

authors： Tang K,Wagner PD,Breen EC

更新日期：2010-02-01 00:00:00

abstract：:The progression of T-lymphoma cells (CCRF-CEM) growing in suspension has been monitored during long term (12-28 h) batch experiments using microcalorimetry. In parallel with the calorimetric measurements, changes in cell concentration, pH, p(O2) and concentrations of the main energy sources (glucose and glutamine) wer...

journal_title：Journal of cellular physiology

authors： Bäckman P,Kimura T,Schön A,Wadsö I

更新日期：1992-01-01 00:00:00

abstract：:Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to Clostridium perfringens enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detached. Nearly half of the cells were non...

journal_title：Journal of cellular physiology

authors： McClane BA,McDonel JL

更新日期：1979-05-01 00:00:00

abstract：:Colon cancer remains one of the lethal malignancies in the world. Aberrant activation of canonical Wnt/β-catenin signaling pathway has been observed in colon cancer. In contrast, the non-canonical Wnt signaling functions remain obscure. Wnt5a is a representative non-canonical Wnt ligand which has gained extensive atte...

journal_title：Journal of cellular physiology

authors： Cheng R,Sun B,Liu Z,Zhao X,Qi L,Li Y,Gu Q

更新日期：2014-12-01 00:00:00

abstract：:The galactosylsphingosine psychosine (Psy) is one of the sphingolipids and induce the formation of multinuclear cells in several cell lines by inhibiting cytokinesis. In the present report, we show that intracellular organelles, including wheat germ agglutinin (WGA)-positive vesicles and early endosomes, are selective...

journal_title：Journal of cellular physiology

authors： Kanazawa T,Takematsu H,Yamamoto A,Yamamoto H,Kozutsumi Y

更新日期：2008-05-01 00:00:00

abstract：:Addition of ATP to cultures of transformed mouse fibroblasts, 3T6 cells, resulted in cell growth inhibition, whereas the growth of the non-transformed counterparts, 3T3 cells, was only slightly affected. The inhibition was found to be specific for adenine nucleotides, and concentration dependent. At relatively low con...

journal_title：Journal of cellular physiology

authors： Belzer I,Friedberg I

更新日期：1989-09-01 00:00:00

abstract：:The development of acute pancreatitis (AP) is triggered by acinar events, but the subsequent extra-acinar events, particularly a distinct immune response, appear to determine its severity. Cytokines modulate this immune response and are derived not only from immunocytes but also from pancreatic acinar cells. We studie...

journal_title：Journal of cellular physiology

authors： Gallmeier E,Schäfer C,Moubarak P,Tietz A,Plössl I,Huss R,Göke B,Wagner AC

更新日期：2005-04-01 00:00:00

abstract：:Tyrosine hydroxylase (TH), catalyzing the conversion of tyrosine into l-DOPA, is the rate-limiting enzyme in dopamine synthesis. Defects in insulin action contribute to alterations of TH expression and/or activity in the brain and insulin increases TH levels in 1-methyl-4-phenylpyridinium (MPP+)-treated neuronal cells...

journal_title：Journal of cellular physiology

authors： Fiory F,Mirra P,Nigro C,Pignalosa FC,Zatterale F,Ulianich L,Prevete N,Formisano P,Beguinot F,Miele C

更新日期：2019-07-01 00:00:00

abstract：:Past work has shown that delta-opioid receptor (DOR) activation by [D-Ala(2),D-Leu(5)]-enkephalin (DADLE) attenuated the disruption of K(+) homeostasis induced by hypoxia or oxygen-glucose deprivation (OGD) in the cortex, while naltrindole, a DOR antagonist blocked this effect, suggesting that DOR activity stabilizes ...

journal_title：Journal of cellular physiology

authors： Chao D,Bazzy-Asaad A,Balboni G,Xia Y

更新日期：2007-07-01 00:00:00

abstract：:In quiescent human fibroblasts stimulated to proliferate by fresh medium plus 15% serum, no changes were seen in the incorporation of 3H tryptophan into the protein of nuclear ribonucleoprotein during the first three hours following re-feeding. This was in contrast to non-histone chromosomal proteins where the incorpo...

journal_title：Journal of cellular physiology

authors： Augenlicht LH,Lipkin M

更新日期：1977-07-01 00:00:00

abstract：:Apoptosis is involved in both the cellular and humoral immune system destroying tumors. An apoptosis-inducing factor from HL-60 myeloid leukemia cells was obtained, purified, and sequenced. The protein found has been identified as a human complement factor B-derived fragment Bb, although it is known that factor B is a...

journal_title：Journal of cellular physiology

authors： Uwai M,Terui Y,Mishima Y,Tomizuka H,Ikeda M,Itoh T,Mori M,Ueda M,Inoue R,Yamada M,Hayasawa H,Horiuchi T,Niho Y,Matsumoto M,Ishizaka Y,Ikeda K,Ozawa K,Hatake K

更新日期：2000-11-01 00:00:00

abstract：:Skeletal muscle atrophy/wasting is associated with impaired protein metabolism in diverse physiological and pathophysiological conditions. Elevated levels of reactive oxygen species (ROS), disturbed redox status, and weakened antioxidant defense system are the major contributing factors toward atrophy. Regulation of p...

journal_title：Journal of cellular physiology

authors： Kaur N,Gupta P,Saini V,Sherawat S,Gupta S,Dua A,Kumar V,Injeti E,Mittal A

更新日期：2019-05-01 00:00:00

abstract：:While dental mesenchymal stem cells are well-studied, the origin of these cells is still unclear. Bone marrow-derived cells (BMDCs) have the potential to engraft into several tissues after injury, but whether they can become dental tissue-specific progenitor cells under normal conditions and the relationship of these ...

journal_title：Journal of cellular physiology

authors： Zhou J,Shi S,Shi Y,Xie H,Chen L,He Y,Guo W,Wen L,Jin Y

更新日期：2011-08-01 00:00:00

abstract：:The growth response of cultured rat intestinal epithelial (RIE-1) cells to epidermal growth factor (EGF) depends on the cell population density. EGF stimulated the proliferation of RIE-1 cells in dense cultures, but inhibited the proliferation of cells growing at low population densities. In contrast, insulin enhanced...

journal_title：Journal of cellular physiology

authors： Blay J,Brown KD

更新日期：1986-12-01 00:00:00

abstract：:Chrysophanol is an anthraquinone compound, mainly isolated from rhubarb, with anti-cancer effects on some types of cancer cells. However, effects of chrysophanol on human choriocarcinoma cells are not known. Therefore, the objective of this study was to determine effects of chrysophanol on choriocarcinoma cells (JAR a...

journal_title：Journal of cellular physiology

authors： Lim W,Yang C,Bazer FW,Song G

更新日期：2017-02-01 00:00:00

abstract：:The zafirlukast has been reported to be anti-inflammatory and widely used to alleviate the symptoms of asthma. However, its influence on insulin secretion in pancreatic β-cells has not been investigated. Herein, we examined the effects of zafirlukast on insulin secretion and the potential underlying mechanisms. Among ...

journal_title：Journal of cellular physiology

authors： Hwang HJ,Park KS,Choi JH,Cocco L,Jang HJ,Suh PG

更新日期：2018-11-01 00:00:00

abstract：:Multiple modalities for lung cancer therapy have emerged in the past decade, whereas their clinical applications and survival-beneficiary is little known. Vaccination with dendritic cells (DCs) or DCs/cytokine-induced killer (CIK) cells has shown limited success in the treatment of patients with advanced non-small-cel...

journal_title：Journal of cellular physiology

authors： Mohsenzadegan M,Peng RW,Roudi R

更新日期：2020-01-01 00:00:00

abstract：:A process of unconventional secretion that is dependent on the Golgi stacking protein GRASP and multiple components of the autophagy machinery has recently been documented for several cytoplasmic and membrane protein. Classical secretion via the exocytic pathway is inhibited during cell division in animal cells, as ke...

journal_title：Journal of cellular physiology

authors： Tang BL

更新日期：2013-05-01 00:00:00

abstract：:We examined the role of superoxide in the increase in intracellular pH (pHi) of human histiocytic leukemia U937 cells treated with 4 beta-phorbol-12,13-didecanoate (4 beta-PDD) or serum. 4 beta-PDD or serum induced a rapid increase in pHi, and antioxidants such as superoxide dismutase (SOD), vitamin E, and butylated h...

journal_title：Journal of cellular physiology

authors： Shibanuma M,Kuroki T,Nose K

更新日期：1988-08-01 00:00:00

abstract：:Synovial fibroblasts (SFs) of rheumatoid arthritis (RA) are phenotypically aggressive, typically progressing into arthritic cartilage degradation. Throughout our study, we made explorations into the effects of microRNA-135a (miR-135a) on the SFs involved in RA by mediating the phosphatidylinositol 3-kinase (PI3K)/AKT ...

journal_title：Journal of cellular physiology

authors： Qu Y,Zhang YP,Wu J,Jie LG,Deng JX,Zhao DB,Yu QH

更新日期：2019-08-01 00:00:00

abstract：:Macrophages and many chemokines are closely associated with the adipogenic differentiation of bone marrow mesenchymal stem cells (MSCs), but their roles in adipogenesis and the underlying mechanisms are not fully understood. Here, we first investigated the influence of macrophages on the differentiation of MSCs in vit...

journal_title：Journal of cellular physiology

authors： Cao D,Ma F,Ouyang S,Liu Z,Li Y,Wu J

更新日期：2019-06-01 00:00:00