Analysis of the relation between alopecia and resistance to 1,25-dihydroxyvitamin D.

abstract：:A new model has been established for the perfused in situ rat lung. During perfusion with glucose at 4 mmol/l, physiological concentrations of insulin (50 mu/l) caused an initial 1.5 fold increase in lactate production; the increase being sustained at 30% for the 4 h of perfusion. The observation that the lung respond...

journal_title：Clinical endocrinology

authors： Stubbs WA,Morgan I,Lloyd B,Alberti KG

更新日期：1977-09-01 00:00:00

abstract：OBJECTIVE:Cadmium (Cd) has been shown to impair pubertal development in experimental animals. However, no data are available for male adolescents with increased urinary cadmium levels. DESIGN:The aim of this cross-sectional study was to evaluate pubertal onset and pituitary-gonadal axis hormones in male adolescents wi...

journal_title：Clinical endocrinology

authors： Interdonato M,Pizzino G,Bitto A,Galfo F,Irrera N,Mecchio A,Pallio G,Ramistella V,De Luca F,Santamaria A,Minutoli L,Marini H,Squadrito F,Altavilla D

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Resistance to thyroid hormone (RTH) is associated with a varied clinical presentation. The cardiac effects of RTH have been described but vascular function has yet to be fully evaluated in this condition. We have measured the arterial function of those with RTH to assess any vascular changes. DESIGN:An obser...

journal_title：Clinical endocrinology

authors： Owen PJ,Chatterjee VK,John R,Halsall D,Lazarus JH

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:There is increasing evidence for the role of cytokines in pituitary differentiated function and tumorigenesis, but the spectrum of cytokines found in the pituitary is unknown. Therefore profiles of cytokine expression were determined in different human anterior pituitary adenoma sub-types. DESIGN:The reverse...

journal_title：Clinical endocrinology

authors： Green VL,Atkin SL,Speirs V,Jeffreys RV,Landolt AM,Mathew B,Hipkin L,White MC

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVES:Bilateral adrenalectomy may be indicated in patients with Cushing's disease in whom hypercortisolism is not resolved after pituitary microsurgery. However, Nelson's syndrome is a major long-term complication of such therapy. We have carried out a longitudinal study on patients with Cushing's disease who unde...

journal_title：Clinical endocrinology

authors： Moreira AC,Castro M,Machado HR

更新日期：1993-07-01 00:00:00

abstract：:The role of endogenous opiate peptides in puerperal hyperprolactinaemia, and in the control of TSH in hypothyroidism, has been investigated. Although exogenous opioids raise prolactin and TSH levels, 16 mg naloxone administered to women on days 2-4 of the puerperium produced no significant change in serum prolactin an...

journal_title：Clinical endocrinology

authors： Grossman A,West S,Williams J,Evans J,Rees LH,Besser GM

更新日期：1982-03-01 00:00:00

abstract：CONTEXT:Transient thelarche (TT), that is, the appearance, regression and subsequent reappearance of breast buds, is a frequent phenomenon, but little is known about pubertal transition in these girls. OBJECTIVE:To describe pubertal progression, growth, genotypes, reproductive hormones and growth factors in girls with...

journal_title：Clinical endocrinology

authors： Soto J,Pereira A,Busch AS,Almstrup K,Corvalan C,Iñiguez G,Juul A,Mericq V

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To compare ultrasonography and 99mTc thyroid scintigraphy for the aetiologic diagnosis of permanent congenital hypothyroidism (CH). STUDY DESIGN:Eighty-eight consecutive patients with CH were recruited at an endocrinology outpatient clinic and submitted to high-frequency ultrasonography and to 99mTc scintigr...

journal_title：Clinical endocrinology

authors： Kreisner E,Camargo-Neto E,Maia CR,Gross JL

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:Mutations in SLC16A2, the gene encoding the thyroid hormone (TH)-specific transporter monocarboxylate transporter 8 (MCT8), result in a thyroid phenotype and severe mental retardation caused by neuronal TH deficiency. These mutational effects raise the question of whether polymorphic variation in SLC16A2 may ...

journal_title：Clinical endocrinology

authors： Lago-Lestón R,Iglesias MJ,San-José E,Areal C,Eiras A,Araújo-Vilar D,Lado-Abeal J,Domínguez-Gerpe L

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:We compared the effectiveness of high intensity focused ultrasound (HIFU) and radioiodine (RAI) to treat patients carrying toxic thyroid nodule (TTN). Normalization of serum thyrotropin (TSH) 1 year after treatment was the primary end-point; concurrent changes in nodules' volume and scintigraphic pattern were a...

journal_title：Clinical endocrinology

authors： Giovanella L,Piccardo A,Pezzoli C,Bini F,Ricci R,Ruberto T,Trimboli P

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Both severe growth hormone (GH) deficiency in hypopituitary adults and physiological ageing are associated with an increase in fat mass, dyslipidaemia, and an increased incidence of cardiovascular disease. Ageing is also associated with a physiological decrease in spontaneous as well as stimulated GH secretio...

journal_title：Clinical endocrinology

authors： Vahl N,Klausen I,Christiansen JS,Jørgensen JO

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:Human GH treatment of short children who had intrauterine growth retardation (IUGR) results in a highly variable growth response. The object of this study was to test the hypothesis that differences in responsiveness to exogenously administered GH might reflect differences in endogenous GH secretion or sensit...

journal_title：Clinical endocrinology

authors： Frank GR,Cheung PT,Horn JA,Alfaro MP,Smith EP,Chernausek SD

更新日期：1996-06-01 00:00:00

abstract：:Recent evidence suggests that oxytocin (OXT) and arginine vasopressin (AVP) are involved in the response to stress. We have examined the changes in peripheral plasma OXT during abdominal surgery in eight patients (six males, two female; ages 60-82 years) undergoing hemicolectomy and compared the results with those for...

journal_title：Clinical endocrinology

authors： Nussey SS,Page SR,Ang VT,Jenkins JS

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Autonomous cortisol secretion of adrenal incidentalomas (AIs) is associated with poor cardiovascular outcome. Because centripetal obesity is a cardiovascular risk factor, we aimed to investigate whether autonomous cortisol secretion is associated with increased visceral fat accumulation. DESIGN:Retrospective...

journal_title：Clinical endocrinology

authors： Yener S,Baris M,Peker A,Demir O,Ozgen B,Secil M

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Staging systems applied to medullary thyroid cancer (MTC) rely on initial clinical and pathological features and do not consider the response to treatment. To determine whether MTC staging can be improved by incorporating the first postoperative calcitonin measurement. PATIENTS AND MEASUREMENTS:Eighty-five p...

journal_title：Clinical endocrinology

authors： Yang JH,Lindsey SC,Camacho CP,Valente FO,Germano-Neto F,Machado AL,Mamone MC,Brodskyn F,Biscolla RP,Tuttle RM,Dias-da-Silva MR,Maciel RM

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the volumetric bone mineral density (BMD) in girls with Turner's syndrome (TS) before and during growth hormone (GH) treatment in combination with low dose oestrogens as well as three years after discontinuation of GH treatment. DESIGN:In a prospective, randomized injectio...

journal_title：Clinical endocrinology

authors： Sass TC,De Muinck Keizer-Schrama SM,Stijnen T,Asarfi A,Van Leeuwen WJ,Van Teunenbroek A,Van Rijn RR,Drop SL

更新日期：2000-05-01 00:00:00

abstract：:A 32-year-old Caucasian male, clinically euthyroid, with paranoid schizophrenia and granulocytopenia, had elevated total and free serum T4 and T3; serum TSH was normal (2.7 +/- 0.7 micronU/ml). There was no goitre present, no evidence of Graves' disease, and no evidence of pituitary tumour. He had a normal response to...

journal_title：Clinical endocrinology

authors： Tamagna EI,Carlson HE,Hershman JM,Reed AW

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:We examined the individual pharmacological effects of the addition of rosiglitazone and metformin to glimepiride on inflammatory markers and adipokines in patients with type 2 diabetes mellitus. We analysed the relationships between these variables, the measurements of insulin sensitivity and beta-cell functi...

journal_title：Clinical endocrinology

authors： Kim HJ,Kang ES,Kim DJ,Kim SH,Ahn CW,Cha BS,Nam M,Chung CH,Lee KW,Nam CM,Lee HC

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by chronic anovulation, hyperandrogenism, polycystic ovary morphology (PCOM) and metabolic disturbances including insulin resistance and type 2 diabetes mellitus. Although insulin resistance could be associated with PCOM, r...

journal_title：Clinical endocrinology

authors： Hong SH,Sung YA,Hong YS,Jeong K,Chung H,Lee H

更新日期：2017-10-01 00:00:00

abstract：CONTEXT:Few studies have evaluated the metabolic outcomes of growth hormone (GH) treatment in idiopathic short stature (ISS). Moreover, children with ISS appear to need higher GH doses than children with GH deficiency (GHD) to achieve the same amount of growth and may therefore be at increased risk of adverse events du...

journal_title：Clinical endocrinology

authors： Decker R,Albertsson-Wikland K,Kriström B,Nierop AF,Gustafsson J,Bosaeus I,Fors H,Hochberg Z,Dahlgren J

更新日期：2010-09-01 00:00:00

abstract：:We report a patient with unilateral thyroid carcinoma, who developed hyperfunction of the thyroid gland during the metastatic progression of the thyroid carcinoma. Concurrently with this event, TSI increased and it is suggested that the differentiated aggressive metastatic thyroid neoplasm had initiated the autoimmune...

journal_title：Clinical endocrinology

authors： Steffensen FH,Aunsholt NA

更新日期：1994-11-01 00:00:00

abstract：:A controlled therapeutic trial on seventy-four 70-year-old women was carried out with the purpose of finding the optimal treatment for post menopausal osteoporosis. The bone mineral content (BMC) was measured by I-photonabsorptiometry at two sites in the distal part of the forearms, where the trabecular/cortical ratio...

journal_title：Clinical endocrinology

authors： Jensen GF,Christiansen C,Transbøl I

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVES:There is growing evidence for the association between bone mineral density (BMD) and vascular calcification, which is related to cardiovascular disease. Coronary multidetector row computed tomography (MDCT) is a noninvasive tool developed to evaluate coronary status precisely. We used MDCT to evaluate this a...

journal_title：Clinical endocrinology

authors： Choi SH,An JH,Lim S,Koo BK,Park SE,Chang HJ,Choi SI,Park YJ,Park KS,Jang HC,Shin CS

更新日期：2009-11-01 00:00:00

abstract：:Only five cases of growth hormone secreting pituitary carcinoma have been documented. We present a 49-year-old West Indian male with grossly elevated plasma growth hormone (760-10,400 mU/l), and a large aggressive pituitary tumour that continued to grow despite repeated pituitary surgery, radiotherapy and medical ther...

journal_title：Clinical endocrinology

authors： Stewart PM,Carey MP,Graham CT,Wright AD,London DR

更新日期：1992-08-01 00:00:00

abstract：:The thyroid functional parameters of 102 children with protein-calorie malnutrition (PCM) classified as undernourished, marasmic, kwashiorkor and marasmic-kwashiorkor were studied by measuring the serum T4, T3, T3 percentage uptake (T3%UT), free thyroxine index (FTI), and (in a few subjects) TSH. Total plasma proteins...

journal_title：Clinical endocrinology

authors： Onuora C,Maharajan G,Singh A,Etta KM

更新日期：1983-01-01 00:00:00

abstract：:In recent years the techniques of molecular and cellular biology have made it possible to begin to dissect the origins and behaviour of the ACTH-secreting tumour cell. It is becoming apparent that these tumours represent undifferentiated neuroendocrine cells, and it may be that their peptide-secreting properties may h...

journal_title：Clinical endocrinology

authors： White A,Clark AJ

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To study the mechanism through which mifepristone interrupts folliculogenesis. DESIGN:Normally ovulating women undergoing donor intrauterine insemination (IUI) treatment were investigated during two menstrual cycles treated with gonadotrophins. In the first cycle (FSH cycle), the women were given 150 IU reco...

journal_title：Clinical endocrinology

authors： Messinis IE,Krishnan M,Kazem R,Khadilkar S,Templeton AA

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Disturbances in the GH/IGF-I axis are reported in 25-60% of short children born small for gestational age (SGA). We hypothesized that these abnormalities might be related to abnormalities in the pituitary region. Therefore, the results of magnetic resonance imaging (MRI) of short SGA children were compared t...

journal_title：Clinical endocrinology

authors： Arends NJ,V d Lip W,Robben SG,Hokken-Koelega AC

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Pseudohypoparathyroidism type Ia (PHP-Ia) is a hereditary disorder characterized by resistance to multiple hormones that work via cAMP such as PTH and TSH, accompanied by typical skeletal features including short stature and brachydactyly, termed Albright hereditary osteodystrophy (AHO). In affected kindreds,...

journal_title：Clinical endocrinology

authors： Mouallem M,Shaharabany M,Weintrob N,Shalitin S,Nagelberg N,Shapira H,Zadik Z,Farfel Z

更新日期：2008-02-01 00:00:00

abstract：:After administration of intravenous metoclopramide, a dopaminergic receptor blocking agent, no rise in thyroid stimulating hormone (TSH) could be found in patients with chronic renal failure, in contrast to non-uraemic controls. Basal TSH values were normal in the uraemic patients but the TSH response to thyrotrophin-...

journal_title：Clinical endocrinology

authors： Weetman AP,Weightman DR,Scanlon MF

更新日期：1981-11-01 00:00:00