Growth hormone secreting pituitary carcinoma: a case report and literature review.

abstract：OBJECTIVE:To study the mechanism through which mifepristone interrupts folliculogenesis. DESIGN:Normally ovulating women undergoing donor intrauterine insemination (IUI) treatment were investigated during two menstrual cycles treated with gonadotrophins. In the first cycle (FSH cycle), the women were given 150 IU reco...

journal_title：Clinical endocrinology

authors： Messinis IE,Krishnan M,Kazem R,Khadilkar S,Templeton AA

更新日期：1997-03-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:Nonfunctioning pituitary adenomas (NFPAs) are the most common subtype of pituitary tumour. Hypopituitarism is observed in NFPAs due to tumour- or treatment-related factors and may increase mortality risk. Here, we analysed the associations of hypopituitarism, hormone replacement and mortality in a...

journal_title：Clinical endocrinology

authors： O'Reilly MW,Reulen RC,Gupta S,Thompson CA,Dineen R,Goulden EL,Bugg G,Pearce H,Toogood AA,Gittoes NJ,Mitchell R,Thompson CJ,Ayuk J

更新日期：2016-11-01 00:00:00

abstract：:The measurement of serum intact parathyroid hormone (PTH) (1-84) over a 24-h period has shown the existence of a circadian rhythm in normal males which is absent in patients with primary hyperparathyroidism. The physiological significance of this observation is reflected in the presence of parallel changes in nephroge...

journal_title：Clinical endocrinology

authors： Logue FC,Fraser WD,Gallacher SJ,Cameron DA,O'Reilly DS,Beastall GH,Patel U,Boyle IT

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:We investigated the clinical usefulness of thyroid blood-flow measurement in predicting relapse of Graves' disease (GD) in comparison with known risk factors for GD relapse. MEASUREMENT:Thyroid blood flow was measured in pulsed Doppler mode at the inferior thyroid artery (ITA), and the peak systolic velocity...

journal_title：Clinical endocrinology

authors： Ueda M,Inaba M,Kumeda Y,Nagasaki T,Hiura Y,Tahara H,Onoda N,Ishikawa T,Nishizawa Y

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To assess the clinical and neurological outcomes in newborns with primary congenital hypothyroidism presented with delayed TSH elevation (dTSH), and to define parameters that may predict the evolution of transient vs. permanent hypothyroidism in these newborns. DESIGN AND PATIENTS:An observational study was ...

journal_title：Clinical endocrinology

authors： Zung A,Radi A,Almashanu S

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:PCOS is associated with obesity and insulin resistance. Efforts have focused on whether an abnormal energy homeostasis contributes to the development of obesity in these patients. There are conflicting results in the literature regarding whether women with PCOS have an altered basal metabolic rate (BMR), ther...

journal_title：Clinical endocrinology

authors： Churchill SJ,Wang ET,Bhasin G,Alexander C,Bresee C,Pall M,Azziz R,Mathur R,Pisarska MD

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Fracture risk in type 2 diabetes mellitus with insulin resistance is increased, despite relatively preserved bone mineral density (BMD). In this study, we investigated the relationship between insulin resistance and composite indices of femoral neck strength in Koreans. DESIGN:A population-based, cross-secti...

journal_title：Clinical endocrinology

authors： Ahn SH,Kim H,Kim BJ,Lee SH,Koh JM

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Obesity disproportionately affects African Americans (AA) (especially women), and is linked to depressed 25-hydroxyvitamin D (25-OH D) and elevated parathyroid hormone (PTH). The relationship of 25-OH D and PTH with body composition and size in AA is not well known. OBJECTIVE:To determine the relationship o...

journal_title：Clinical endocrinology

authors： Valiña-Tóth AL,Lai Z,Yoo W,Abou-Samra A,Gadegbeku CA,Flack JM

更新日期：2010-05-01 00:00:00

abstract：:The growth hormone (GH) and prolactin (PRL) responses to metoclopramide (MCP) were compared to those with arginine and insulin-induced hypoglycaemia in eight children. While a significant rise in GH release after stimulation with arginine and insulin occurred in all subjects (P less than 0.05), no significant increase...

journal_title：Clinical endocrinology

authors： Ijaiya K,Roth B,Schwenk A

更新日期：1980-06-01 00:00:00

abstract：CONTEXT & OBJECTIVE:A recent paper by our group reported that regular aerobic exercise during pregnancy led to lower foetal IGF-I and IGF-II concentrations and a modest reduction in offspring birth weight when compared with the offspring of nontraining control participants. Maternal hormonal alterations in response to ...

journal_title：Clinical endocrinology

authors： Hopkins SA,Baldi JC,Cutfield WS,McCowan L,Hofman PL

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Discontinuation of dopamine agonist (DA) treatment in women with prolactinoma after menopause is a potential approach; studies systematically assessing long-term outcomes are lacking. Our aim was to investigate the natural history of prolactinoma in this group. DESIGN/PATIENTS:Retrospective cohort study of w...

journal_title：Clinical endocrinology

authors： Santharam S,Fountas A,Tampourlou M,Arlt W,Ayuk J,Gittoes N,Toogood A,Karavitaki N

更新日期：2018-09-01 00:00:00

abstract：:A 39-year-old woman presented with amenorrhoea, hyperprolactinaemia and sellar mass. Bromocriptine normalized PRL levels but failed to suppress tumour growth. Subsequently, she developed clinical signs and elevated blood cortisol levels consistent with a diagnosis of Cushing's disease. A pituitary tumour was removed w...

journal_title：Clinical endocrinology

authors： Ikeda H,Yoshimoto T,Kovacs K,Horvath E

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:Diagnosing thyroid nodules preoperatively using traditional diagnostic tools - ultrasonography (US) and cytology - still carries a considerable degree of uncertainty, and surgery is recommended for a far from negligible number of patients simply for diagnostic purposes. Thyroid elastosonography (USE) and BRAF...

journal_title：Clinical endocrinology

authors： Nacamulli D,Nico L,Barollo S,Zambonin L,Pennelli G,Girelli ME,Casal Ide E,Pelizzo MR,Vianello F,Negro I,Watutantrige-Fernando S,Mantero F,Rugge M,Mian C

更新日期：2012-10-01 00:00:00

abstract：:A modified short ACTH test for the detection of heterozygote carriers of 21-hydroxylase deficiency (21-OHD) was applied to twenty-one controls and fourteen parents of children with 21-OHD. The following modifications were introduced: (1) Endogenous ACTH was suppressed by dexamethasone administration prior to the test,...

journal_title：Clinical endocrinology

authors： Lejeune-Lenain C,Cantraine F,Dufrasnes M,Prevot F,Wolter R,Franckson JR

更新日期：1980-06-01 00:00:00

abstract：OBJECTIVE:Autonomous cortisol secretion of adrenal incidentalomas (AIs) is associated with poor cardiovascular outcome. Because centripetal obesity is a cardiovascular risk factor, we aimed to investigate whether autonomous cortisol secretion is associated with increased visceral fat accumulation. DESIGN:Retrospective...

journal_title：Clinical endocrinology

authors： Yener S,Baris M,Peker A,Demir O,Ozgen B,Secil M

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To determine whether treatment with transdermal oestrogen replacement therapy (TERT) in postmenopausal women with type 2 diabetes mellitus was able to increase the activity of constitutive nitric oxide synthase (cNOS) in platelets. RESEARCH DESIGN AND METHODS:Eighteen postmenopausal women with type 2 diabete...

journal_title：Clinical endocrinology

authors： Martina V,Bruno GA,Origlia C,Gaia D,Trucco F,Pescarmona G

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:No single histological or molecular marker is diagnostic for malignant phaeochromocytomas and paragangliomas (PPGLs). This study aimed to establish and evaluate a prognostic nomogram to improve the prediction of metastatic probability in individual PPGL patients. METHODS:Three hundred and 47 consecutive PPGL...

journal_title：Clinical endocrinology

authors： Zhong X,Ye L,Su T,Xie J,Zhou W,Jiang Y,Jiang L,Ning G,Wang W

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Cabergoline therapy normalizes prolactin levels and reduces the size of macroprolactinomas. However there are no data indicating whether cabergoline can normalize growth hormone secretion in patients who were growth hormone deficient at the time of diagnosis of a macroprolactinoma. SUBJECTS AND METHODS:We st...

journal_title：Clinical endocrinology

authors： George LD,Nicolau N,Scanlon MF,Davies JS

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Papillary thyroid cancer (PTC) is a common endocrine cancer and commonly presents with lymph node (LN) metastases. The role of surgical removal of the central cervical LN compartment is poorly defined. There are no prospective randomized controlled trials addressing the relevance to the extent of the initial...

journal_title：Clinical endocrinology

authors： Mulla M,Schulte KM

更新日期：2012-01-01 00:00:00

abstract：:The thyroid functional parameters of 102 children with protein-calorie malnutrition (PCM) classified as undernourished, marasmic, kwashiorkor and marasmic-kwashiorkor were studied by measuring the serum T4, T3, T3 percentage uptake (T3%UT), free thyroxine index (FTI), and (in a few subjects) TSH. Total plasma proteins...

journal_title：Clinical endocrinology

authors： Onuora C,Maharajan G,Singh A,Etta KM

更新日期：1983-01-01 00:00:00

abstract：:This study deals with serum prolactin concentrations during various conditions in the early puerperium in an attempt to investigate some characteristics of the mechanisms responsible for the regulation of the lactotropes. In nursing, in non-nursing, non-medicated and in non-nursing, bromocriptine-treated women prolact...

journal_title：Clinical endocrinology

authors： Vemer HM,Rolland R

更新日期：1981-08-01 00:00:00

abstract：UNLABELLED:Objective To evaluate the effect of strontium ranelate (SR) on bone turnover markers in women with established osteoporosis previously treated with teriparatide (TPTD--recombinant human PTH 1-34). DESIGN PATIENTS: Twenty-two postmenopausal Caucasian women (aged 65.7 +/- 1.7 years) with established osteoporos...

journal_title：Clinical endocrinology

authors： Anastasilakis AD,Goulis DG,Polyzos SA,Gerou S,Ballaouri I,Efstathiadou Z,Kita M,Avramidis A

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Women with polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. The contribution of lipid abnormalities to this higher risk, in particular atherogenic modifications of low density lipoprotein (LDL) such as a shift towards smaller LDL, has not been properly explored. We aimed to e...

journal_title：Clinical endocrinology

authors： Dejager S,Pichard C,Giral P,Bruckert E,Federspield MC,Beucler I,Turpin G

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:It has previously been shown that patients with postpartum pituitary necrosis (Sheehan's syndrome, SS) have paradoxically increased TSH levels and loss of the nocturnal TSH surge. This study sought to determine the circadian and pulsatile characteristics of TSH secretion underlying those abnormalities. DESIG...

journal_title：Clinical endocrinology

authors： MacCagnan P,Oliveira JH,Castro V,Abucham J

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:We determined the effect of subclinical hyperthyroidism (defined as low circulating TSH with normal serum free T4) and subclinical hypothyroidism (raised serum TSH with normal free T4) on fasting levels of blood lipids. DESIGN:Prospective study of lipid concentrations in patients identified as having abnorma...

journal_title：Clinical endocrinology

authors： Parle JV,Franklyn JA,Cross KW,Jones SR,Sheppard MC

更新日期：1992-11-01 00:00:00

abstract：:Serum prolactin concentrations have been measured at 15 min intervals for 2 h on 240 occasions in 227 patients with symptoms which could have been due to hyperprolactinaemic gonadal dysfunction. Of the 227, 138 had at least one elevated random prolactin level. Overall, 22% showed no significant fluctuation in prolacti...

journal_title：Clinical endocrinology

authors： Moult PJ,Dacie JE,Rees LH,Besser GM

更新日期：1981-04-01 00:00:00

abstract：:We have studied the effects of dopamine on the secretion of TSH and its subunits in vivo and in vitro. Four normal controls, seven patients with primary hypothyroidism, two patients with peripheral resistance to thyroid hormone (PRTH), and two patients with alpha-secreting pituitary tumours underwent a 3-h dopamine in...

journal_title：Clinical endocrinology

authors： Cooper DS,Klibanski A,Ridgway EC

更新日期：1983-03-01 00:00:00

abstract：:In recent years the techniques of molecular and cellular biology have made it possible to begin to dissect the origins and behaviour of the ACTH-secreting tumour cell. It is becoming apparent that these tumours represent undifferentiated neuroendocrine cells, and it may be that their peptide-secreting properties may h...

journal_title：Clinical endocrinology

authors： White A,Clark AJ

更新日期：1993-08-01 00:00:00

abstract：:This study was to examine indirectly the effect of endogenous progesterone, a known competitor for 5 alpha-reductase, on androgen metabolism in target organs in hirsute women. Serum levels of progesterone, testosterone (T), androstenedione (A), dihydrotestosterone (DHT) and 5 alpha-androstane 3 alpha 17 beta-diol (3 a...

journal_title：Clinical endocrinology

authors： Dewis P,Newman M,Anderson DC

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:Hyperandrogenism is one of the characteristic features of the polycystic ovary syndrome (PCOS). Androgens are important for bone mass. Studies on bone mineral density (BMD) and fractures in postmenopausal women with PCOS are lacking. The aim of this study was to investigate whether postmenopausal women with P...

journal_title：Clinical endocrinology

authors： Schmidt J,Dahlgren E,Brännström M,Landin-Wilhelmsen K

更新日期：2012-08-01 00:00:00