Abstract:
:Noradrenaline enhanced in a concentration-dependent way the basal release of endogenous GABA from superfused rat hippocampus synaptosomes. The alpha 2-adrenoceptor antagonist yohimbine prevented the releasing effect of noradrenaline while the alpha 1-adrenoceptor antagonist prazosin was ineffective. It is concluded that GABAergic nerve terminals in rat hippocampus possess adrenoceptors of the alpha 2-subtype whose activation causes enhancement of GABA release.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Pittaluga A,Raiteri Mdoi
10.1016/0304-3940(87)90430-7subject
Has Abstractpub_date
1987-05-19 00:00:00pages
363-7issue
3eissn
0304-3940issn
1872-7972pii
0304-3940(87)90430-7journal_volume
76pub_type
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