Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Colizoli O,de Gee JW,Urai AE,Donner THdoi
10.1038/s41598-018-33559-9subject
Has Abstractpub_date
2018-10-23 00:00:00pages
15904issue
1issn
2045-2322pii
10.1038/s41598-018-33559-9journal_volume
8pub_type
已发布勘误abstract::Human immunodeficiency virus type 1 (HIV-1) infection promotes a generalized activation of host responses that involves not only CD4 T cells, but also cells of the microenvironment, which are not directly infected, such as endothelial cells. The mechanisms triggering HIV-1-associated vascular alterations remain poorly...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44743-w
更新日期:2019-07-16 00:00:00
abstract::Herein, we propose an advanced energy-storage system: all-graphene-battery. It operates based on fast surface-reactions in both electrodes, thus delivering a remarkably high power density of 6,450 W kg(-1)(total electrode) while also retaining a high energy density of 225 Wh kg(-1)(total electrode), which is comparabl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05278
更新日期:2014-06-13 00:00:00
abstract::We propose an internal (on-chip) Wheatstone bridge configuration to evaluate the efficiency of near-field transducers (NFT) as used in heat-assisted magnetic recording (HAMR). The electric field enhancement between the transducer and the image plane is monitored by measuring the resistance of metal electrodes composin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24423
更新日期:2016-04-14 00:00:00
abstract::Enhancing endogenous cannabinoid (eCB) signaling has been considered as a potential strategy for the treatment of stress-related conditions. Fatty acid amide hydrolase (FAAH) represents the primary degradation enzyme of the eCB anandamide (AEA), oleoylethanolamide (OEA) and palmitoylethanolamide (PEA). This study desc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20895-z
更新日期:2018-02-05 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-62684-7
更新日期:2020-04-03 00:00:00
abstract::Solid stress is a biomechanical abnormality of the tumor microenvironment that plays a crucial role in tumor progression. When it is applied to cancer cells, solid stress hinders their proliferation rate and promotes cancer cell invasion and metastatic potential. However, the underlying mechanisms of how it is implica...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37425-6
更新日期:2019-01-30 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. The genomic landscape of the PDAC genome features four frequently mutated genes (KRAS, CDKN2A, TP53, and SMAD4) and dozens of candidate driver genes altered at low frequency, including potential clinical targets. Circulating cell-free...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep18425
更新日期:2015-12-16 00:00:00
abstract::Antiretroviral therapy-naive HIV-1 infected infants experience poor viral containment and rapid disease progression compared to adults. Viral factors (e.g. transmitted cytotoxic T- lymphocyte (CTL) escape mutations) or infant factors (e.g. reduced CTL functional capacity) may explain this observation. We assessed CTL ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29536
更新日期:2016-07-12 00:00:00
abstract::Sesame is prized for its oil. Genetic improvement of sesame can be enhanced through marker-assisted breeding. However, few simple sequence repeat (SSR) markers and SSR-based genetic maps were available in sesame. In this study, 7,357 SSR markers were developed from the sesame genome and transcriptomes, and a genetic m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08858-2
更新日期:2017-08-21 00:00:00
abstract::Cadherin-related 23 (CDH23) is an adhesive protein important for hearing and vision, while CAMSAP3/Marshalin is a microtubule (MT) minus-end binding protein that regulates MT networks. Although both CDH23 and CAMSAP3/Marshalin are expressed in the organ of Corti, and carry several protein-protein interaction domains, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28706
更新日期:2016-06-28 00:00:00
abstract::Basic leucine zippers (bZIPs) form a large plant transcription factor family. C and S1 bZIP groups can heterodimerize, fulfilling crucial roles in seed development and stress response. S1 sequences also harbor a unique regulatory mechanism, termed Sucrose-Induced Repression of Translation (SIRT). The conservation of b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30444
更新日期:2016-07-26 00:00:00
abstract::Conventional effluent trading systems (ETSs) between point sources (PSs) and nonpoint sources (NPSs) are often unreliable because of the uncertain characteristics of NPSs. In this study, a new framework was established for PS-NPS ETSs, and a comprehensive analysis was conducted by quantifying the impacts of the uncert...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29398
更新日期:2016-07-11 00:00:00
abstract::A new semiconducting phase of two-dimensional phosphorous in the Kagome lattice is proposed from first-principles calculations. The band gaps of the monolayer (ML) and bulk Kagome phosphorous (Kagome-P) are 2.00 and 1.11 eV, respectively. The magnitude of the band gap is tunable by applying the in-plane strain and/or ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23151
更新日期:2016-03-16 00:00:00
abstract::The remineralization mechanism in dental caries lesions is not completely understood. This study reports on ultrastructural and chemical changes observed within arrested caries lesions. Carious human teeth were observed using scanning electron microscopy (SEM) and focused-ion-beam (FIB)-SEM. The crystals detected in t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61111-1
更新日期:2020-03-09 00:00:00
abstract::Sweet potato leaf curl virus (SPLCV) causes yield losses in sweet potato cultivation. Diagnostic techniques such as serological detection have been developed because these plant viruses are difficult to treat. Serological assays have been used extensively with recombinant antibodies such as whole immunoglobulin or sin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64996-0
更新日期:2020-05-15 00:00:00
abstract::Potential distributions of endemic relic shrubs in western Ordos were poorly mapped, which hindered our implementation of proper conservation. Here we investigated the applicability of ecological niche modeling for endangered relic shrubs to detect areas of priority for biodiversity conservation and analyze difference...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26268
更新日期:2016-05-20 00:00:00
abstract::Genome editing has emerged as a technology with a potential to revolutionize plant breeding. In this study, we report on generating, in less than ten months, Tomelo, a non-transgenic tomato variety resistant to the powdery mildew fungal pathogen using the CRISPR/Cas9 technology. We used whole-genome sequencing to show...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00578-x
更新日期:2017-03-28 00:00:00
abstract::The vertical migration of zooplankton and micronekton (hereafter 'zooplankton') has ramifications throughout the food web. Here, we present the first evidence that climate fluctuations affect the vertical migration of zooplankton in the Southern Ocean, based on multi-year acoustic backscatter data from one of the deep...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46423-1
更新日期:2019-07-12 00:00:00
abstract::In this study, Tb3+-doped natural sodium feldspar (NaAlSi3O8) phosphors have been successfully prepared using high-temperature solid-state method with natural sodium feldspar as a substrate. Energy-dispersive X-ray spectrometry analysis (EDX) of NaAlSi3O8 showed that 0.03 wt% of Eu element was present, and elemental d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51171-3
更新日期:2019-10-10 00:00:00
abstract::Hypoplastic left heart syndrome (HLHS) is a fatal congenital heart disease in which the left side of the heart is underdeveloped, impairing the systemic circulation. Underdeveloped left ventricle exerts biomechanical stress on the right ventricle that can progress into heart failure. Genome-wide transcriptome changes ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30896
更新日期:2016-08-03 00:00:00
abstract::Tsetse flies are the transmitting vector of trypanosomes causing human sleeping sickness and animal trypanosomiasis in sub-saharan Africa. 3-alkylphenols are used as attractants in tsetse fly traps to reduce the spread of the disease. Here we present an inexpensive production method for 3-ethylphenol (3-EP) and 3-prop...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66997-5
更新日期:2020-06-19 00:00:00
abstract::A novel one-pot synthesis of tri-substituted purines and the discovery of purine analogues with trypanocidal activity are reported. The reaction is initiated by a metal-free oxidative coupling of primary alkoxides and diaminopyrimidines with Schiff base formation and subsequent annulation in the presence of large N,N-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09139
更新日期:2015-03-16 00:00:00
abstract::The mammalian Major Histocompatibility Complex (MHC) region contains several gene families characterized by highly polymorphic loci with extensive nucleotide diversity, copy number variation of paralogous genes, and long repetitive sequences. This structural complexity has made it difficult to construct a reliable ref...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45518
更新日期:2017-03-31 00:00:00
abstract::Wave retarders having spatially varying optical axes orientations, called q-plates are extremely efficient devices for converting spin to orbital angular momentum of light and for the generation of optical vortices. Most often, these plates are designed for a specific wavelength and have a homogeneous constant retarda...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48163-8
更新日期:2019-08-15 00:00:00
abstract::The non-protein amino acid β-methylamino-L-alanine (BMAA) is a neurotoxin present in microalgae and shown to accumulate in the food web. BMAA has been linked to the complex neurodegenerative disorder of Guam and to increased incidents sporadic ALS. Two main neurotoxic routes are suggested; an excitotoxic by acting as ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29631
更新日期:2016-07-12 00:00:00
abstract::Food thickening agents are used to aid the administration of medicine to elderly patients with dysphagia. Magnesium oxide tablets are sometimes administered with food thickening agents. Non-disintegration and disintegration delay of these tablets in the body are problems associated with food thickening agent use. Howe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73135-8
更新日期:2020-09-30 00:00:00
abstract::This study aimed to evaluate the effects of ketorolac, a commonly used non-steroidal anti-inflammatory drug (NSAID) as patient controlled intravenous infusion analgesia (PCIA) for the patients underwent radical cystectomy (RC) due to bladder cancer regarding post-operational indices of recovery. Total seventy patients...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-018-22677-z
更新日期:2018-03-15 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-23132-9
更新日期:2018-03-19 00:00:00
abstract::Ichthyoarchaeological evidence is uncommon at ancient hunter-gatherer sites from various regions and timeframes. This research contributes to the development of microarchaeological techniques useful for identifying fishing economies in situations where classifiable bones are unavailable. Specifically, traces of heat a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03737-2
更新日期:2017-06-15 00:00:00
abstract::The endogenous peptide C-type natriuretic peptide (CNP) binds its receptor, guanylyl cyclase B (GCB), and is expressed by endothelial cells in diverse tissues. Because the endothelial cells of visceral adipose tissue have recently been reported to play a role in lipid metabolism and inflammation, we investigated the e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10240-1
更新日期:2017-08-29 00:00:00