Correction to: Comorbidity in gout at the time of first diagnosis: sex differences that may have implications for dosing of urate lowering therapy.

abstract：:We investigated the therapeutic potential and mechanism of action of IFN-beta protein for the treatment of rheumatoid arthritis (RA). Collagen-induced arthritis was induced in DBA/1 mice. At the first clinical sign of disease, mice were given daily injections of recombinant mouse IFN-beta or saline for 7 days. Disease...

journal_title：Arthritis research & therapy

authors： van Holten J,Reedquist K,Sattonet-Roche P,Smeets TJ,Plater-Zyberk C,Vervoordeldonk MJ,Tak PP

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:Properdin amplifies the alternative pathway of complement activation. In the present study, we evaluated its role in the development of collagen antibody-induced arthritis (CAIA). METHODS:Arthritis was induced by intraperitoneal injection of a collagen antibody cocktail into properdin-deficient (KO) and w...

journal_title：Arthritis research & therapy

authors： Dimitrova P,Ivanovska N,Belenska L,Milanova V,Schwaeble W,Stover C

更新日期：2012-07-25 00:00:00

abstract：BACKGROUND:Multisite pain and falls are common in older people, and isolated studies have identified multisite pain as a potential falls risk factor. This study aims to synthesise published literature to further explore the relationship between multisite pain and falls and to quantify associated risks. METHODS:Bibliog...

journal_title：Arthritis research & therapy

authors： Welsh VK,Clarson LE,Mallen CD,McBeth J

更新日期：2019-02-22 00:00:00

abstract：:I comment on the well-designed trial by Alda and colleagues reported in a recent issue of Arthritis Research and Therapy which demonstrated some benefits of cognitive-behavioral therapy (CBT) for fibromyalgia (FM). CBT in this and other studies provides statistically significant but rather modest benefits for FM. This...

journal_title：Arthritis research & therapy

authors： Lumley MA

更新日期：2011-01-01 00:00:00

abstract：:The past 10 years have seen the description of families of receptors that drive proinflammatory cytokine production in infection and tissue injury. Two major classes have been examined in the context of inflammatory joint disease--the Toll-like receptors (TLRs) and NOD-like receptors (NLRs). TLRs such as TLR2 and TLR4...

journal_title：Arthritis research & therapy

authors： McCormack WJ,Parker AE,O'Neill LA

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Chronic nonbacterial osteomyelitis (CNO) is an inflammatory disorder of unknown etiology. In children and adolescents CNO predominantly affects the metaphyses of the long bones, but lesions can occur at any site of the skeleton. Prospectively followed cohorts using a standardized protocol in diagnosis and ...

journal_title：Arthritis research & therapy

authors： Beck C,Morbach H,Beer M,Stenzel M,Tappe D,Gattenlöhner S,Hofmann U,Raab P,Girschick HJ

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The FMS-related tyrosine kinase 3 ligand (Flt3L)/CD135 axis plays a fundamental role in proliferation and differentiation of dendritic cells (DCs). As DCs play an important role in rheumatoid arthritis (RA) immunopathology we studied in detail the Flt3L/CD135 axis in RA patients. METHODS:The levels of Flt...

journal_title：Arthritis research & therapy

authors： Ramos MI,Perez SG,Aarrass S,Helder B,Broekstra P,Gerlag DM,Reedquist KA,Tak PP,Lebre MC

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The patient's perspective is becoming increasingly important in clinical and policy decisions. In this study, we aimed to evaluate the preferences of patients with, or at risk of, osteoporosis for medication attributes, and to establish how patients trade between these attributes. METHODS:A discrete choic...

journal_title：Arthritis research & therapy

authors： Hiligsmann M,Dellaert BG,Dirksen CD,van der Weijden T,Goemaere S,Reginster JY,Watson V,Boonen A

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:Interleukin-17A (IL-17A) plays a pathogenic role in several rheumatic diseases including spondyloarthritis and, paradoxically, has been described to both promote and protect from bone formation. We therefore examined the effects of IL-17A on osteoblast differentiation in vitro and on periosteal bone formatio...

journal_title：Arthritis research & therapy

authors： Shaw AT,Maeda Y,Gravallese EM

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We examined the degree to which Patient Global Assessment of Disease Activity (PtGA) was driven by patient-reported assessments of pain (Pain), physical function, and fatigue in patients receiving tofacitinib 5 mg t...

journal_title：Arthritis research & therapy

authors： Strand V,Kaine J,Alten R,Wallenstein G,Diehl A,Shi H,Germino R,Murray CW

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:The receptor activator of NF-κB ligand (RANKL), a member of the TNF ligand superfamily, is known to regulate bone metabolism. The expression of each component of the RANK/RANKL/osteoprotegerin (OPG) system in the intervertebral disc (IVD) has not been examined in detail. The purposes of this study were to ex...

journal_title：Arthritis research & therapy

authors： Takegami N,Akeda K,Yamada J,Sano T,Murata K,Huang J,Masuda K,Sudo A

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Pepsin agglutinators, discovered over 50 years ago, have been recently referred to as anti-hinge antibodies (AHAs) because of their reaction with the IgG hinge epitope. AHAs have different reactivity for each hinge epitope generated by each protease that cleaves the hinge region at different sites. Moreover,...

journal_title：Arthritis research & therapy

authors： Ota T,Ota SI,Uchino A,Nagano S

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:The anti-cyclic citrullinated peptide (CCP) antibody is a diagnostic biomarker of rheumatoid arthritis (RA). However, some non-RA connective tissue disease (CTD) patients also test positive for the anti-CCP antibody and, thus, may ultimately develop RA. We retrospectively investigated whether anti-CCP-positi...

journal_title：Arthritis research & therapy

authors： Iwasaki T,Nakabo S,Terao C,Murakami K,Nakashima R,Hashimoto M,Imura Y,Yukawa N,Yoshifuji H,Miura Y,Yurugi K,Maekawa T,van Delft MAM,Trouw LA,Fujii T,Mimori T,Ohmura K

更新日期：2020-10-19 00:00:00

abstract：:Idiopathic CD4 lymphocytopenia (ICL) is a presumed heterogenous syndrome with key element low CD4 T-cell counts (below 300/mm³) without evidence of HIV infection or other known immunodeficiency. The etiology, pathogenesis, and management of ICL remain poorly understood and inadequately defined. The clinical presentati...

journal_title：Arthritis research & therapy

authors： Zonios D,Sheikh V,Sereti I

更新日期：2012-08-31 00:00:00

abstract：BACKGROUND:Arhalofenate acid, the active acid form of arhalofenate, is a non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand, with uricosuric activity via URAT1 inhibition. Phase II studies revealed decreased acute arthritis flares in arhalofenate-treated gout compared with allopurinol alone. Hence,...

journal_title：Arthritis research & therapy

authors： McWherter C,Choi YJ,Serrano RL,Mahata SK,Terkeltaub R,Liu-Bryan R

更新日期：2018-09-06 00:00:00

abstract：:Anti-glucose-6-phosphate isomerase (GPI) antibodies are known to be arthritogenic autoantibodies in K/BxN mice, although some groups have reported that few healthy humans retain these antibodies. The expression of Fcgamma receptors (FcgammaRs) is genetically regulated and has strong implications for the development of...

journal_title：Arthritis research & therapy

authors： Matsumoto I,Zhang H,Muraki Y,Hayashi T,Yasukochi T,Kori Y,Goto D,Ito S,Tsutsumi A,Sumida T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Stem cell therapy is considered as a promising alternative to treat intervertebral disc degeneration (IDD). Extensive work had been done on identifying and comparing different types of candidate stem cells, both in vivo and in vitro. However, few studies have shed light on degenerative nucleus pulposus cells...

journal_title：Arthritis research & therapy

authors： Han Z,Wang J,Gao L,Wang Q,Wu J

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:Lupus nephritis (LN) is one of the most severe complications of systemic lupus erythematosus (SLE). Circular RNAs (circRNAs) can act as competitive endogenous RNAs (ceRNAs) to regulate gene transcription, which is involved in mechanism of many diseases. However, the role of circRNA in lupus nephritis has bee...

journal_title：Arthritis research & therapy

authors： Zhang C,Gao C,Di X,Cui S,Liang W,Sun W,Yao M,Liu S,Zheng Z

更新日期：2021-01-13 00:00:00

abstract：:Over the last decades, genetic factors for rheumatoid diseases like the HLA haplotypes have been studied extensively. However, during the past years of research, it has become more and more evident that the influence of epigenetic processes on the development of rheumatic diseases is probably as strong as the genetic ...

journal_title：Arthritis research & therapy

authors： Strietholt S,Maurer B,Peters MA,Pap T,Gay S

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) is a common complication of connective tissue disease (CTD) and a leading cause of morbidity and mortality. There are various lung ultrasound (LUS) scoring systems with different lung intercostal spaces (LIS). The purpose of this meta-analysis was to find a simplified LUS meth...

journal_title：Arthritis research & therapy

authors： Xie HQ,Zhang WW,Sun S,Chen XM,Yuan SF,Gong ZH,Liu L

更新日期：2019-04-11 00:00:00

abstract：INTRODUCTION:Ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) share genetic and clinical features. IBD is associated with the presence of antibodies to a variety of commensal microorganisms including anti-Saccharomyces cerevesiae antibodies (ASCA), antineutrophil cytoplasmic antibodies (ANCA), anti-I2 (...

journal_title：Arthritis research & therapy

authors： Wallis D,Asaduzzaman A,Weisman M,Haroon N,Anton A,McGovern D,Targan S,Inman R

更新日期：2013-10-26 00:00:00

abstract：:The relationship between serum urate, menopause, and aging has not been clearly defined by scientific evidence. In the present issue of Arthritis Research and Therapy, Hak and Choi present a cross-sectional analysis to clarify the effect of menopause and hormone replacement therapy on serum urate in women within the T...

journal_title：Arthritis research & therapy

authors： Gaffo AL,Saag KG

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:The microdialysis method was applied to the human knee joint with osteoarthritis (OA) in order to reveal changes in biochemical markers of cartilage and inflammation, intraarticularly and in the synovium, in response to a single bout of mechanical joint loading. METHODS:Thirty-one female subjects with OA ...

journal_title：Arthritis research & therapy

authors： Helmark IC,Mikkelsen UR,Børglum J,Rothe A,Petersen MC,Andersen O,Langberg H,Kjaer M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Persistence of biologic therapy in psoriatic arthritis (PsA) patients is an important factor in individualized patient treatment planning and healthcare policy and guideline development. OBJECTIVE:To estimate the persistence of biologic agents prescribed to PsA patients in a real-life setting as well as fac...

journal_title：Arthritis research & therapy

authors： Haddad A,Gazitt T,Feldhamer I,Feld J,Cohen AD,Lavi I,Tatour F,Bergman I,Zisman D

更新日期：2021-01-29 00:00:00

abstract：BACKGROUND:Some abnormalities in nailfold videocapillaroscopy (NVC), such as the presence of micro-haemorrhages (MHEs), micro-thromboses (MTs), giant capillaries (GCs) and reduction in the number of capillaries (nCs), suggest a disease activity (DA) phase in systemic sclerosis (SSc). In a previous paper, we showed that...

journal_title：Arthritis research & therapy

authors： Andracco R,Irace R,Zaccara E,Vettori S,Maglione W,Riccardi A,Pignataro F,Ferrara R,Sambataro D,Sambataro G,Vitali C,Valentini G,Del Papa N

更新日期：2017-06-13 00:00:00

abstract：INTRODUCTION:The pleiotropic cytokine interleukin-6 (IL-6) plays an important role in the pathogenesis of different diseases, including rheumatoid arthritis (RA). ALX-0061 is a bispecific Nanobody® with a high affinity and potency for IL-6 receptor (IL-6R), combined with an extended half-life by targeting human serum a...

journal_title：Arthritis research & therapy

authors： Van Roy M,Ververken C,Beirnaert E,Hoefman S,Kolkman J,Vierboom M,Breedveld E,'t Hart B,Poelmans S,Bontinck L,Hemeryck A,Jacobs S,Baumeister J,Ulrichts H

更新日期：2015-05-20 00:00:00

abstract：BACKGROUND:Lack of adequate self-care, frequent admissions, and poor quality of life are common and serious problems in adult patients with systemic lupus erythematosus (SLE). Some studies have revealed that transitional care is effective in improving self-care and quality of life as well as reducing rehospitalization ...

journal_title：Arthritis research & therapy

authors： Xie X,Song Y,Yang H,Nie A,Chen H,Li JP

更新日期：2018-08-16 00:00:00

abstract：INTRODUCTION:To date, no single most-appropriate factor or delivery method has been identified for the purpose of mesenchymal stem cell (MSC)-based treatment of cartilage injury. Therefore, in this study we tested whether gene delivery of the growth factor Indian hedgehog (IHH) was able to induce chondrogenesis in huma...

journal_title：Arthritis research & therapy

authors： Steinert AF,Weissenberger M,Kunz M,Gilbert F,Ghivizzani SC,Göbel S,Jakob F,Nöth U,Rudert M

更新日期：2012-07-20 00:00:00

abstract：:Following publication of the original article [1], the authors reported a typesetting error. ...

journal_title：Arthritis research & therapy

authors： Orsolini G,Adami G,Rossini M,Fassio A,Giollo A,Caimmi C,Idolazzi L,Gatti D,Viapiana O

更新日期：2018-11-05 00:00:00

abstract：:Dysregulated psychophysiological responses have been observed in patients with fibromyalgia syndrome (FMS), although the results are inconsistent. Surface electromyographic (EMG), systolic and diastolic blood pressure, heart rate (HR), and skin conductance levels (SCLs) were continuously recorded at baseline, and duri...

journal_title：Arthritis research & therapy

authors： Thieme K,Turk DC

更新日期：2006-01-01 00:00:00