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Multisite pain and self-reported falls in older people: systematic review and meta-analysis.

Abstract：

BACKGROUND:Multisite pain and falls are common in older people, and isolated studies have identified multisite pain as a potential falls risk factor. This study aims to synthesise published literature to further explore the relationship between multisite pain and falls and to quantify associated risks. METHODS:Bibliographic databases were searched from inception to December 2017. Studies of community-dwelling adults aged 50 years and older with a multisite pain measurement and a falls outcome were included. Two reviewers screened articles, undertook quality assessment and extracted data. Random-effects meta-analysis was used to pool the effect estimate (odds ratio (OR) and 95% confidence interval (95%CI)). Heterogeneity was assessed by I2; sensitivity analyses used adjusted risk estimates and exclusively longitudinal studies. RESULTS:The search identified 49,577 articles, 3145 underwent abstract review, 22 articles were included in the systematic review and 18 were included in the meta-analysis. The unadjusted pooled OR of 1.82 (95%CI 1.55-2.13), demonstrating that those reporting multisite pain are at increased risk of falls, is supported by the adjusted pooled OR of 1.56 (95%CI 1.39-1.74). Multisite pain predicts future falls risk (OR = 1.74 (95%CI 1.57-1.93)). For high-quality studies, those reporting multisite pain have double the odds of a future fall compared to their pain-free counterparts. CONCLUSION:Multisite pain is associated with an increased future falls risk in community-dwelling older people. Increasing public awareness of multisite pain as a falls risk factor and advising health and social care professionals to identify older people with multisite pain to signpost accordingly will enable timely falls prevention strategies to be implemented.

journal_name

Arthritis Res Ther

journal_title

Arthritis research & therapy

authors

Welsh VK,Clarson LE,Mallen CD,McBeth J

doi

10.1186/s13075-019-1847-5

subject

Has Abstract

pub_date

2019-02-22 00:00:00

pages

67

issue

1

eissn

1478-6354

issn

1478-6362

pii

10.1186/s13075-019-1847-5

journal_volume

21

pub_type

杂志文章,meta分析

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