Emerging role of SIRT3 in endothelial metabolism, angiogenesis, and cardiovascular disease.

abstract：:Osteoclasts mediate bone resorption by secretion at the site of bone attachment. This process depends on calmodulin concentrated at a specialized acid-secreting membrane. We hypothesized that increased calmodulin and bone attachment were required for acid secretion. We tested this by studying calmodulin, bone attachme...

journal_title：Journal of cellular physiology

authors： Williams JP,Dong SS,Whitaker CH,Jordan SE,Blair HC

更新日期：1996-12-01 00:00:00

abstract：:Cell fusion occurs during fertilization and in the formation of organs such as muscles, placenta, and bones. We have developed an experimental model for epithelial cell fusion which permits analysis of the processes during junction disintegration and formation of polykaryons (Palovuori and Eskelinen [2000] Eur. J. Cel...

journal_title：Journal of cellular physiology

authors： Palovuori R,Myrsky E,Eskelinen S

更新日期：2004-09-01 00:00:00

abstract：:NIH-3T3 cells transformed by the EJ-ras oncogene display reduced platelet-derived growth factor (PDGF)-stimulated phospholipase C activity as measured by inositol 1,4,5-triphosphate (IP3) synthesis and Ca2+ mobilization. The lack of PDGF-stimulated Ca2+ mobilization in EJ-ras transformed cells is not due to a loss of ...

journal_title：Journal of cellular physiology

authors： Olinger PL,Benjamin CW,Gorman RR,Connor JA

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Elevated microsatellite alteration at selected tetranucleotide repeats (EMAST) is a type of microsatellite instability that occurs in ∼60% of colorectal cancers (CRCs) and associated with MSH3 dysfunction. A 5-fluorouracil (5-FU)-related cytotoxicity is attenuated in MSH3-deficient colon cancer cells. Report...

journal_title：Journal of cellular physiology

authors： Mohammadpour S,Goodarzi HR,Jafarinia M,Porhoseingholi MA,Nazemalhosseini-Mojarad E

更新日期：2020-04-01 00:00:00

abstract：:Marrow stromal cells (MSCs) are stem-like cells having a striking somatic plasticity. In fact, besides differentiating into mesenchymal lineages (bone, cartilage, and fat), they are capable of differentiating into neurons and astrocytes in vitro and in vivo. The RB and RB2/P130 genes, belonging to the retinoblastoma g...

journal_title：Journal of cellular physiology

authors： Jori FP,Napolitano MA,Melone MA,Cipollaro M,Cascino A,Giordano A,Galderisi U

更新日期：2004-08-01 00:00:00

abstract：:Recent evidence has verified the cardioprotective actions of irisin in different diseases models. However, the beneficial action of irisin on hypoxia-reoxygenation (HR) injury under high glucose stress has not been described. Herein our research investigated the influence of irisin on HR-triggered cardiomyocyte death ...

journal_title：Journal of cellular physiology

authors： Fan J,Zhu Q,Wu Z,Ding J,Qin S,Liu H,Miao P

更新日期：2020-02-01 00:00:00

abstract：:Leukemic cells in the myeloblastic stage from a murine myeloid leukemia cell line (M1) were induced to differentiate to macrophages by lipopolysaccharide (LPS) from Gram-negative bacteria. A granulocyte-macrophage colony-stimulating factor (CSF) was produced only during differentiation. After induction of differentiat...

journal_title：Journal of cellular physiology

authors： Maeda M,Ichikawa Y

更新日期：1980-03-01 00:00:00

abstract：:Sprouting angiogenesis is a major form of neovascularization of tissues suffering from hypoxia and other related stress. Endothelial cells (ECs) undergo proliferation, differentiation, programmed death, and migration during angiogenic sprouting, but the underlying molecular mechanisms regulating ECs in angiogenesis ha...

journal_title：Journal of cellular physiology

authors： Liu Y,Zheng Q,He G,Zhang M,Yan X,Yang Z,Zhang P,Wang L,Liu J,Liang L,Han H

更新日期：2019-06-01 00:00:00

abstract：:Mitochondrial transcription factor A (TFAM) is responsible for stability, maintenance, and transcriptional control of mitochondrial DNA (mtDNA). We have studied the expression and distribution of TFAM in the gametes and preimplantation embryos of the domestic pig (Sus scrofa). We hypothesized that TFAM is not present ...

journal_title：Journal of cellular physiology

authors： Antelman J,Manandhar G,Yi YJ,Li R,Whitworth KM,Sutovsky M,Agca C,Prather RS,Sutovsky P

更新日期：2008-11-01 00:00:00

abstract：:Insulin gene expression in rat insulinoma (RIN) cells is extinct in RIN x fibroblast hybrids and can reappear upon loss of DNA contributed by the fibroblast parent. (Besnard et al., Exp. Cell Res. 185:101-108, 1989). In the present study, we looked for the role of 5'-flanking sequences of the human insulin gene in the...

journal_title：Journal of cellular physiology

authors： Besnard C,Monthioux E,Loràs P,Jami J,Daegelen D

更新日期：1991-03-01 00:00:00

abstract：:This study examined the role of agonist-induced Rho kinase (ROCK) involvement in the morphological outcome of pulmonary-derived fibroblasts. Normal human lung fibroblasts (NHLF) spontaneously differentiate into network-like structures in a two-dimensional growth factor reduced Matrigel matrix-based assay. Sphingosine ...

journal_title：Journal of cellular physiology

authors： Harvey KA,Paranavitana CN,Zaloga GP,Siddiqui RA

更新日期：2007-05-01 00:00:00

abstract：:Gastric cancer has the fifth highest incidence of disease and is the third leading cause of cancer-associated mortality in the world. The etiology of gastric cancer is complex and needs to be fully elucidated. Thus, it is necessary to explore potential pathogenic genes and pathways that contribute to gastric cancer. G...

journal_title：Journal of cellular physiology

authors： Ren F,Zhao Q,Liu B,Sun X,Tang Y,Huang H,Mei L,Yu Y,Mo H,Dong H,Zheng P,Mi Y

更新日期：2020-03-01 00:00:00

abstract：:The effects of ouabain on the growth of murine lymphoblasts in vitro have been studied. Exposure of cells to ouabain (0.1 mM) initially inhibited 86Rb+ uptake rate, reduced the intracellular potassium concentration, and decreased population growth rates. Continued exposure to the same ouabain concentration resulted in...

journal_title：Journal of cellular physiology

authors： Cuff JM,Lichtman MA

更新日期：1975-04-01 00:00:00

abstract：:Cells are quite sensitive to a change of the extracellular pH and respond to it through detection of the H+/HCO3- level in extracellular fluid. However, little is known about molecular details induced by acidosis, such as intracellular pathways and gene expression. Here we describe properties of gene expression, prote...

journal_title：Journal of cellular physiology

authors： Shimokawa N,Kumaki I,Qiu CH,Ohmiya Y,Takayama K,Koibuchi N

更新日期：2005-10-01 00:00:00

abstract：:Infection with Verotoxin producing Escherichia coli (VTEC) has been implicated in hemolytic uremic syndrome, the leading cause of pediatric renal failure. Verotoxin (VT) binds to globotriaosylceramide (Gal alpha 1-4Gal beta 1-4GlcCer Gb3) in susceptible cells. Gb3 is required for cytotoxicity and toxin-resistant cells...

journal_title：Journal of cellular physiology

authors： Pudymaitis A,Lingwood CA

更新日期：1992-03-01 00:00:00

abstract：:A method, based on the differing capacities of cells to adhere to a column of polyester fibres, has been described for separating human bone marrow cells into a nonadherent and an adherent fraction. The effect of this cell separation procedure on colony formation by erythroid progenitor cells was investigated. In cont...

journal_title：Journal of cellular physiology

authors： Aye MT

更新日期：1977-04-01 00:00:00

abstract：:Numerous studies have reported that long noncoding RNA (lncRNA) dysregulation is involved in the progression of many malignant tumors, including glioma. The lncRNA ZNFX1 antisense RNA 1 (ZFAS1) plays an oncogenic role in various malignant tumors, such as gastric cancer and hepatocellular carcinoma. However, the underl...

journal_title：Journal of cellular physiology

authors： Li X,Luo Y,Liu L,Cui S,Chen W,Zeng A,Shi Y,Luo L

更新日期：2020-03-01 00:00:00

abstract：:Sleep-disordered breathing with recurrent apnea (periodic cessation of breathing) results in chronic intermittent hypoxia (IH), which leads to cardiovascular and respiratory pathology. Molecular mechanisms underlying IH-evoked cardio-respiratory co-morbidities have not been delineated. Mice with heterozygous deficienc...

journal_title：Journal of cellular physiology

authors： Yuan G,Nanduri J,Khan S,Semenza GL,Prabhakar NR

更新日期：2008-12-01 00:00:00

abstract：:Interleukin-1 is a proinflammatory and immunomodulatory cytokine that plays a crucial role in inflammatory diseases of the skin, including bacterial infections, bullous diseases, UV damage, and especially psoriasis. To characterize the molecular effects of IL-1 in epidermis, we defined the transcriptional changes in h...

journal_title：Journal of cellular physiology

authors： Yano S,Banno T,Walsh R,Blumenberg M

更新日期：2008-01-01 00:00:00

abstract：:A successful aging could be gained by life satisfaction, social functioning, or psychological resources and, definitely, by increasing resistance to diverse age-related pathologies. Nowadays, cancer can be considered an age-related disease since the incidence of most cancers increases with age, rising more rapidly beg...

journal_title：Journal of cellular physiology

authors： Tramontano D,De Amicis F

更新日期：2018-11-01 00:00:00

abstract：:Cell- and matrix-related parameters, which characterize the aging and differentiation process of cartilage in vivo, were measured in cultured chick epiphyseal chondrocytes during maintenance in a suspension culture for 34 days. A gradual decrease in the rates of proliferation and an increase in the size of the cells w...

journal_title：Journal of cellular physiology

authors： Beit-Or A,Nevo Z,Kalina M,Eilam Y

更新日期：1990-08-01 00:00:00

abstract：:Signal transduction of fibroblast growth factor (FGF) receptors is known to involve tyrosine phosphorylation of several substrates, including Grb2, phospholipase C-gamma, and phosphatidylinositol 3-kinase, whereas the role of G-proteins in FGF receptor signaling is controversial. In the present study we investigated t...

journal_title：Journal of cellular physiology

authors： Piiper A,Stryjek-Kaminska D,Gebhardt R,Zeuzem S

更新日期：1996-04-01 00:00:00

abstract：:To construct a long noncoding RNA (lncRNA)-microRNA (miRNA)-messenger RNA (mRNA) regulatory network related to epithelial ovarian cancer (EOC) cisplatin-resistant, differentially expressed genes (DEGs), differentially expressed lncRNAs (DELs), and differentially expressed miRNAs (DEMs) between MDAH and TOV-112D cells ...

journal_title：Journal of cellular physiology

authors： Zhao X,Tang DY,Zuo X,Zhang TD,Wang C

更新日期：2019-11-01 00:00:00

abstract：:Over the past decade, a wide range of scientific investigations have been performed to reveal neuropathological aspects of cognitive disorders; however, only limited therapeutic approaches currently exist. The failures of conventional therapeutic options as well as the predicted dramatic rise in the prevalence of cogn...

journal_title：Journal of cellular physiology

authors： Farzaei MH,Bahramsoltani R,Abbasabadi Z,Braidy N,Nabavi SM

更新日期：2019-03-01 00:00:00

abstract：:Effects of interstitial fluid flow on osteoblasts were investigated. Intracellular cyclic adenosine monophosphate (cAMP) levels were monitored in cultured osteoblasts subjected to shear rates ranging from 10 to 3,500 sec-1. Cyclic AMP levels were significantly increased at all shear rates from 1 pmole/mg protein to 10...

journal_title：Journal of cellular physiology

authors： Reich KM,Gay CV,Frangos JA

更新日期：1990-04-01 00:00:00

abstract：:We have examined the transport of amino acids by the sodium-dependent "A" and "ASC" system in thymic- and splenic-derived lymphocytes from the Long-Evans rat. Lymphocytes derived from the thymus transport amino acids by both the "A" and "ASC" systems, whereas lymphocytes from the spleen transport amino acids by the "A...

journal_title：Journal of cellular physiology

authors： Wise WC

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVE:This study aimed to explore the underlying function of Gubenxiezhuo dialysis on the distribution of gut microflora uremia. METHODS:A uremia rat model was constructed, and the morphology of renal tissue was determined using the hematoxylin-eosin (H&E) staining. Moreover, the blood samples were collected and t...

journal_title：Journal of cellular physiology

authors： He H,Hu P,Tang Y,Xu X

更新日期：2019-07-01 00:00:00

abstract：:Low-power laser irradiation (LPLI) has been shown to exert promotive effects on cell survival and proliferation through activation of various signaling pathways. Estrogen receptors (ERs, ERα, and ERβ) are ligand-activated transcription factors, which regulate target gene expression, promote cell proliferation, and res...

journal_title：Journal of cellular physiology

authors： Huang L,Tang Y,Xing D

更新日期：2013-05-01 00:00:00

abstract：:Vitamin D3 metabolites regulate the differentiation of chondrocytes isolated from the growth zone or resting zone of rat costochondral cartilage. Since some of the direct membrane effects of vitamin D metabolites are nongenomic, we hypothesized that protein kinase C (PKC) plays a role in signal transduction for these ...

journal_title：Journal of cellular physiology

authors： Sylvia VL,Schwartz Z,Schuman L,Morgan RT,Mackey S,Gomez R,Boyan BD

更新日期：1993-11-01 00:00:00

abstract：:We have previously observed major differences in the phosphorylation of membrane proteins in sparse, proliferating versus confluent, quiescent pig aortic endothelial cells (EC) (Kazlauskas and DiCorleto, 1987). In the present study we examined whether EC growth state can influence the activity of a specific phosphoryl...

journal_title：Journal of cellular physiology

authors： Uratsuji Y,DiCorleto PE

更新日期：1988-09-01 00:00:00