PML down-regulation in soft tissue sarcomas.

abstract：:Lung diseases are major cause of morbidity and mortality worldwide. The progress in regenerative medicine and stem cell research in the lung are currently a fast-growing research topic that can provide solutions to these major health problems. Under normal conditions, the rate of cellular proliferation is relatively l...

journal_title：Journal of cellular physiology

authors： Zhu Y,Chen X,Yang X,El-Hashash A

更新日期：2018-10-01 00:00:00

abstract：:HeLa (substrain Ho) grown in serum free medium showed an increase in the specific activity of alkaline phosphatase when fetal calf serum (10%) was added to the medium (9.7 nmoles/sec/mg protein to 86.8). Under the same conditions, eight intracellular enzymes showed no increase in activity. Similar results were obtaine...

journal_title：Journal of cellular physiology

authors： Carlson CW

更新日期：1979-01-01 00:00:00

abstract：:gamma-Glutamyl transpeptidase has multi-catalytic activities. It degrades glutathione and can produce ammonia from glutamine. The present study was designed to examine whether the decreased cell proliferation, cellular glutathione content and concurrent increase in ammonia production in senescent cells in culture are ...

journal_title：Journal of cellular physiology

authors： Takahashi S,Nakagawa S,Zeydel M,Bhargava G

更新日期：1985-10-01 00:00:00

abstract：:During interphase, the centrosome concentrates cell stress response molecules, including chaperones and proteasomes, into a proteolytic center. However, whether the centrosome functions as proteolytic center during mitosis is not known. In this study, cultured mammalian cells were treated with the proteasome inhibitor...

journal_title：Journal of cellular physiology

authors： Ehrhardt AG,Sluder G

更新日期：2005-09-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is mainly associated with hepatitis B virus (HBV) infection and characterized by metastasizing and infiltrating adjacent and distant tissues. Notably, microRNA-1271 (miR-1271) is a tumor suppressor in various cancers. Therefore, we evaluate the ability of miR-1271 to influence cell proli...

journal_title：Journal of cellular physiology

authors： Chen Y,Zhao ZX,Huang F,Yuan XW,Deng L,Tang D

更新日期：2019-04-01 00:00:00

abstract：:Lung cancer is a main cause of death all over the world with a high incidence rate. Metastasis into neighboring and distant tissues as well as resistance of cancer cells to chemotherapy demand novel strategies in lung cancer therapy. Curcumin is a naturally occurring nutraceutical compound derived from Curcuma longa (...

journal_title：Journal of cellular physiology

authors： Ashrafizadeh M,Najafi M,Makvandi P,Zarrabi A,Farkhondeh T,Samarghandian S

更新日期：2020-12-01 00:00:00

abstract：:Four cell lines, named nonparenchymal 11 (NP11), NP26, NP31, and NP32, were established from sinusoidal endothelial cells (SECs) of rat liver. They still retained expression of receptors for vascular endothelial growth factor (VEGF), Fit-1, and kinase domain-containing receptor (KDR). NP31 and NP32 turned out to be in...

journal_title：Journal of cellular physiology

authors： Maru Y,Yamaguchi S,Takahashi T,Ueno H,Shibuya M

更新日期：1998-08-01 00:00:00

abstract：:An analysis of which component of lipopolysaccharides (LPS), the lipid or the polysaccharide (PS), is active in stimulating the murine granulopoietic system has been performed. LPS with different structures, isolated from different mutant strains of Salmonella and chemical degradation products of lipopolysaccharides h...

journal_title：Journal of cellular physiology

authors： Apte RN,Galanos C,Pluznik DH

更新日期：1976-01-01 00:00:00

abstract：:Pyroptosis is a form of necrotic and inflammatory programmed cell death, which could be characterized by cell swelling, pore formation on plasma membranes, and release of proinflammatory cytokines (IL-1β and IL-18). The process of pyroptosis presents as dual effects: protecting multicellular organisms from microbial i...

journal_title：Journal of cellular physiology

authors： Lu F,Lan Z,Xin Z,He C,Guo Z,Xia X,Hu T

更新日期：2020-04-01 00:00:00

abstract：:The possibility that one or both of the synthetic triamines, 1,3,6-triaminohexane and 1,4,7-triaminoheptane, could substitute for the naturally occurring polyamines in the growth of SV-3T3 cells was investigated. It was found that these triamines did lead to a restoration of growth in cells in which spermidine content...

journal_title：Journal of cellular physiology

authors： McGovern KA,Clark RS,Pegg AE

更新日期：1986-05-01 00:00:00

abstract：:Derivation of insulin producing cells (IPCs) from embryonic stem (ES) cells provides a potentially innovative form of treatment for type 1 diabetes. Here, we discuss the current state of the art, unique challenges, and future directions on generating IPCs. ...

journal_title：Journal of cellular physiology

authors： Raikwar SP,Zavazava N

更新日期：2009-02-01 00:00:00

abstract：:The differentiation of mesenchymal stem cells (MSCs) into type II alveolar epithelial (AT II) cells in vivo and in vitro, is critical for reepithelization and recovery in acute lung injury (ALI), but the mechanisms responsible for differentiation are unclear. In the present study, we investigated the role of the canon...

journal_title：Journal of cellular physiology

authors： Liu AR,Liu L,Chen S,Yang Y,Zhao HJ,Liu L,Guo FM,Lu XM,Qiu HB

更新日期：2013-06-01 00:00:00

abstract：:Bone morphogenetic protein-2 (BMP-2), a member of transforming growth factor-beta superfamily, plays a crucial role in migration and metastasis of human cancer cells. Integrins are the major adhesive molecules in mammalian cells. Here we found that BMP-2 directed the migration and increased cell surface and mRNA expre...

journal_title：Journal of cellular physiology

authors： Fong YC,Li TM,Wu CM,Hsu SF,Kao ST,Chen RJ,Lin CC,Liu SC,Wu CL,Tang CH

更新日期：2008-12-01 00:00:00

abstract：:The peroxisome proliferation-activated receptor gamma (PPARgamma) is mainly expressed in the adipose tissue and integrates the control of energy, lipid, and glucose homeostasis. The present study, by means of RT-PCR, Western blot, and immunofluorescence techniques, demonstrates that human sperm express the PPARgamma. ...

journal_title：Journal of cellular physiology

authors： Aquila S,Bonofiglio D,Gentile M,Middea E,Gabriele S,Belmonte M,Catalano S,Pellegrino M,Andò S

更新日期：2006-12-01 00:00:00

abstract：:Restitution is a crucial event during the healing of superficial injury of the gastric mucosa involving epithelial cell sheet movement into the damaged area. We demonstrated that growth factors promote the restitution of human gastric epithelial cells. However, the intracellular signaling pathways that transmit extrac...

journal_title：Journal of cellular physiology

authors： Tétreault MP,Chailler P,Beaulieu JF,Rivard N,Ménard D

更新日期：2008-02-01 00:00:00

abstract：:Glycochenodeoxycholate (GCDA) is closely associated with carcinogenesis and chemoresistance of hepatocellular carcinoma (HCC). Signal transducer and activator of transcription 3 (STAT3), a transcription factor, is involved in various human tumors. Whether GCDA induces chemoresistance through STAT3 and the mechanism of...

journal_title：Journal of cellular physiology

authors： Wang J,Zhou M,Jin X,Li B,Wang C,Zhang Q,Liao M,Hu X,Yang M

更新日期：2020-03-01 00:00:00

abstract：:In order to study the generation, factors controlling endogenous folate pools, and their functional importance, Friend erythroleukemia cells were grown in media containing 100; 1,000; and 10,000 ng/ml of tritiated pteroylglutamic acid (3H)PteGlu1 and then studied in unlabeled media with varying amounts of PteGlu1. The...

journal_title：Journal of cellular physiology

authors： Steinberg SE,Fonda S,Campbell CL,Hillman RS

更新日期：1983-02-01 00:00:00

abstract：:We have previously shown that 24,25-(OH)2D3 plays a major role in resting zone (RC) chondrocyte differentiation and that this vitamin D metabolite regulates protein kinase C (PKC). The aim of the present study was to identify the signal transduction pathway used by 24,25-(OH)2D3 to stimulate PKC activation. Confluent,...

journal_title：Journal of cellular physiology

authors： Helm S,Sylvia VL,Harmon T,Dean DD,Boyan BD,Schwartz Z

更新日期：1996-12-01 00:00:00

abstract：:The endocannabinoid system (ECS) is activated at the onset of obesity and diverse metabolic diseases. Endocannabinoids mediate their physiological and behavioral effects by activating specific cannabinoid receptors, mainly cannabinoid receptor 1 (CB(1)R). Diabetic nephropathy (DN) is induced by hyperlipidemia, and ren...

journal_title：Journal of cellular physiology

authors： Lim JC,Lim SK,Han HJ,Park SH

更新日期：2010-11-01 00:00:00

abstract：:Dishevelled-associated activator of morphogenesis 1 (DAAM1) is a formin-family protein involved in nucleation of unbranched actin filaments and in cytoskeletal organization through Wnt-Dishevelled PCP pathway, which participates in essential biological processes, such as cell polarity, movement, and adhesion during mo...

journal_title：Journal of cellular physiology

authors： Pariante P,Dotolo R,Venditti M,Ferrara D,Donizetti A,Aniello F,Minucci S

更新日期：2016-10-01 00:00:00

abstract：:Cancer is one of the common lifestyle diseases and is considered to be the leading cause of death worldwide. Epstein-Barr virus (EBV)-infected individuals remain asymptomatic; but under certain stress conditions, EBV may lead to the development of cancers such as Burkitt's and Hodgkin's lymphoma and nasopharyngeal car...

journal_title：Journal of cellular physiology

authors： Ojha R,Nandani R,Prajapati VK

更新日期：2019-05-01 00:00:00

abstract：:Considerable evidence has accumulated for a role of a nonsteroidal mevalonate product in the regulation of DNA replication and cell division. We report here a similar requirement for mevalonate in a nonreplicative function, that of natural killer (NK) cell cytotoxicity. Treatment of NK cells with 10 microM compactin f...

journal_title：Journal of cellular physiology

authors： Cutts JL,Scallen TJ,Watson J,Bankhurst AD

更新日期：1989-06-01 00:00:00

abstract：:In this study, we developed an injectable in situ forming hydrogel/microparticle system consisting of two drugs, melatonin and methylprednisolone, to investigate the capability of the system for chondrogenesis in vitro and in vivo. The chemical, mechanical, and rheological properties of the hydrogel/microparticle were...

journal_title：Journal of cellular physiology

authors： Naghizadeh Z,Karkhaneh A,Nokhbatolfoghahaei H,Farzad-Mohajeri S,Rezai-Rad M,Dehghan MM,Aminishakib P,Khojasteh A

更新日期：2021-03-01 00:00:00

abstract：:The metabolome is a data-rich source of information concerning all the low-molecular-weight metabolites in a biofluid, which can indicate early biological changes to the host due to perturbations in metabolic pathways. Major changes can be seen after minor stimuli, which make it a valuable target for analysis. Due to ...

journal_title：Journal of cellular physiology

authors： Johnson CH,Gonzalez FJ

更新日期：2012-08-01 00:00:00

abstract：:Lung cancer (LC) is the leading cause of cancer-related deaths all over the world, among both men and women, with an incidence of over 200,000 new cases per year coupled with a very high mortality rate. LC comprises of two major clinicopathological categories: small-cell (SCLC) and nonsmall-cell lung carcinoma (NSCLC)...

journal_title：Journal of cellular physiology

authors： Uddin A,Chakraborty S

更新日期：2018-04-20 00:00:00

abstract：:This study aimed at investigating the expression and function of uracil nucleotide-sensitive receptors (P2Y(2), P2Y(4), and P2Y(6)) on osteogenic differentiation of human bone marrow stromal cells (BMSCs) in culture. Bone marrow specimens were obtained from postmenopausal female patients (68 ± 5 years old, n = 18) und...

journal_title：Journal of cellular physiology

authors： Noronha-Matos JB,Costa MA,Magalhães-Cardoso MT,Ferreirinha F,Pelletier J,Freitas R,Neves JM,Sévigny J,Correia-de-Sá P

更新日期：2012-06-01 00:00:00

abstract：:Interleukin-34 (IL-34) shares a common receptor with macrophage colony-stimulating factor (M-CSF), and can bind to CSF-1R, induces lymphocytes differentiation, proliferation, and regulates the synthesis of inflammatory components. Recent findings reported aberrant expression of IL-34 in several autoimmune disorders, s...

journal_title：Journal of cellular physiology

authors： Xu WD,Huang AF,Fu L,Liu XY,Su LC

更新日期：2019-12-01 00:00:00

abstract：:Polyoma transformed hamster cells (PyBHK) and SV40 transformed mouse cells (SV3T3) were transferred in culture using crystalline trypsin followed by neutralisation with soybean trypsin inhibitor. Such cells were able to proliferate freely in defined medium without any serum supplement and without any intervening perio...

journal_title：Journal of cellular physiology

authors： Bush H,Shodell M

更新日期：1977-03-01 00:00:00

abstract：:Mitochondrial (mt) dysfunction and oxidative stress are involved in the pathogenesis of ischemia/reperfusion (I/R)-injury. Lycopene, a lipophilic antioxidant found mainly in tomatoes and in other vegetables and fruits, can protect mtDNA against oxidative damage. However, the role of mtDNA in myocardial I/R-injury is u...

journal_title：Journal of cellular physiology

authors： Yue R,Xia X,Jiang J,Yang D,Han Y,Chen X,Cai Y,Li L,Wang WE,Zeng C

更新日期：2015-09-01 00:00:00

abstract：:The genetic factors known to be involved in the final realization of beta-glucuronidase activity in mice are considered from the standpoint of structural genes determining the catalytic activity of enzyme molecules as well as the recognition features of enzyme molecules that identify them for subsequent processing by ...

journal_title：Journal of cellular physiology

authors： Paigen K,Swank RT,Tomino S,Ganschow RE

更新日期：1975-04-01 00:00:00