当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > The protective effect of polysaccharide extracted from Portulaca oleracea L. against Pb-induced learning and memory impairments in rats.

The protective effect of polysaccharide extracted from Portulaca oleracea L. against Pb-induced learning and memory impairments in rats.

Abstract：

:This paper studied the extraction of polysaccharide from Portulaca oleracea L. (POP) by hot water extraction and ethanol precipitation. Structural properties of the extracted polymers were determined. POP was composed of rhamnose, arabinose and galactose in ratios of 1: 2.34: 3.07 with a molecular weight of 1.55 × 107 Da. The neuroprotective effect of POP on Pb-induced neuronal toxicity was then evaluated in vitro and in vivo test. Treatment with POP markedly increased the survival of PC12 cells and repressed the generation of reactive oxygen species following Pb exposure. In Morris water maze analysis, Pb exposure led to an increase in escape latency and a decrease in platform crossing times of rats in the probe test, which could be attenuated by POP treatment. Additionally, the Pb-induced loss of dendritic spine was recovered after feeding rats with POP at 600 mg/kg/day. These results indicated that Pb-induced cognitive impairments could be inhibited by POP.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Tao H,Ye DL,Wu YL,Han MM,Xue JS,Liu ZH,Chen XT,Wang HL

doi

10.1016/j.ijbiomac.2018.07.138

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

617-623

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(18)32791-0

journal_volume

119

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Heteronuclear nuclear magnetic resonance assignments, structure and dynamics of SUMO-1, a human ubiquitin-like protein.

    abstract：:The structure of a ubiquitin-like protein, small ubiquitin-related modifier-1 (SUMO-1), was earlier determined using homonuclear nuclear magnetic resonance (NMR) spectroscopy, since the spectral quality of the protein was not suitable for heteronuclear NMR data collection. In this study, a slightly different construct...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/s0141-8130(00)00169-0

    authors： Jin C,Shiyanova T,Shen Z,Liao X

    更新日期：2001-03-14 00:00:00

  • Synthesis, structural characterization, QSAR and docking studies of a new binuclear nickel (II) complex based on the flexible tetradentate N-donor ligand as a potent antibacterial and anticancer agent.

    abstract：:A new nickel (II)complex namely [Ni2(Lt)Cl4] derived from the NiCl2.6H2O and 1,1,3,3-tetrakis(3,5-dimethyl-1-pyrazolyl)propane (Lt) has been synthesized and fully characterized by the single crystal X-ray diffraction, elemental analysis, FT-IR, UV-vis, density functional theory (DFT) calculations, antibacterial and an...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.06.098

    authors： Beheshti A,Hashemi F,Behavndi F,Zahedi M,Kolahi M,Motamedi H,Mayer P

    更新日期：2017-11-01 00:00:00

  • Characterization and antioxidant activities of polysaccharides from the leaves of Lilium lancifolium Thunb.

    abstract：:In this study, LLP-1, LLP-2, and LLP-3 three novel polysaccharide fractions were purified from the leaves of Lilium lancifolium, and their physicochemical characterizations and antioxidant properties were investigated by chemical methods, high performance gel permeation chromatography (HPGPC), high performance liquid ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.07.028

    authors： Xu Z,Wang H,Wang B,Fu L,Yuan M,Liu J,Zhou L,Ding C

    更新日期：2016-11-01 00:00:00

  • Comparative study on citric acid modified instant starches (alcoholic alkaline treated) isolated from white sorghum and corn grains.

    abstract：:This study investigated the impact of citric acid modification combined with alcoholic-alkaline treatment on physicochemical, textural and rheological properties of sorghum and corn starches. Both starches were modified with citric acid (CA) using concentrations (20 and 40%) w/w and were named as SCA and CCA, respecti...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.10.143

    authors： Zehra N,Mohsin Ali T,Hasnain A

    更新日期：2020-05-01 00:00:00

  • Organisation of the external region of the starch granule as determined by infrared spectroscopy.

    abstract：:Attenuated total reflectance-Fourier transform infrared (ATR-FTIR) was used to study the external regions of starch granules. Native starches (wheat, potato, maize, waxy maize and amylomaize) were analysed and compared to gelatinised and acid-hydrolysed starches. The IR spectra of potato and amylomaize starches were c...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/s0141-8130(02)00067-3

    authors： Sevenou O,Hill SE,Farhat IA,Mitchell JR

    更新日期：2002-12-20 00:00:00

  • Influence of the method of purification on some solution properties of welan gum.

    abstract：:The origin and some consequences of the presence of aggregates and impurities (deriving from the fermentation procedure) on the solution properties of welan gum have been studied. For this purpose, a method of purification was developed for a fermentation welan broth. It was verified that this method is ineffective fo...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(94)90030-2

    authors： Lopes L,Milas M,Rinaudo M

    更新日期：1994-10-01 00:00:00

  • Study the effect of trypsin enzyme activity on the screening of applying frontal affinity chromatography.

    abstract：:Frontal affinity chromatography (FAC) combined with enzyme has been widely used for drug screening. In this paper, the effect of target enzyme activity on screening of bioactive compounds was studied through applying FAC. Trypsin with different degree of inactivation were prepared as target enzyme by thermal denaturat...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.07.218

    authors： Qian J,Zhao C,Tong J,Jiang S,Zhang Z,Lu S,Guo H

    更新日期：2019-10-15 00:00:00

  • Characterization of a purified decolorizing detergent-stable peroxidase from Streptomyces griseosporeus SN9.

    abstract：:A novel extracellular lignin peroxidase (called LiP-SN) was produced and purified from a newly isolated Streptomyces griseosporeus strain SN9. The findings revealed that the pure enzyme was a monomeric protein with an estimated molecular mass of 43 kDa and a Reinheitzahl value of 1.63. The 19 N-terminal residue sequen...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.11.021

    authors： Rekik H,Nadia ZJ,Bejar W,Kourdali S,Belhoul M,Hmidi M,Benkiar A,Badis A,Sallem N,Bejar S,Jaouadi B

    更新日期：2015-02-01 00:00:00

  • Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing.

    abstract：:Lyophilized wafers comprising sodium alginate (SA) and gelatin (GE) (0/100, 75/25, 50/50, 25/75, 0/100 SA/GE, respectively) with silver sulfadiazine (SSD, 0.1% w/w) have been developed for potential application on infected chronic wounds. Polymer-drug interactions and physical form were characterized by Fourier transf...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.04.048

    authors： Boateng J,Burgos-Amador R,Okeke O,Pawar H

    更新日期：2015-08-01 00:00:00

  • Aspergillus oryzae S2 alpha-amylase production under solid state fermentation: optimization of culture conditions.

    abstract：:Aspergillus oryzae S2 was assayed for alpha-amylase production under solid state fermentation (SSF). In addition to AmyA and AmyB already produced in monitored submerged culture, the strain was noted to produce new AmyB oligomeric forms, in particular a dominant tetrameric form named AmyC. The latter was purified to h...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.01.026

    authors： Sahnoun M,Kriaa M,Elgharbi F,Ayadi DZ,Bejar S,Kammoun R

    更新日期：2015-04-01 00:00:00

  • Structural-functional insights and studies on saccharide binding of Sophora japonica seed lectin.

    abstract：:Functional and conformational transitions of the Sophora japonica seed lectin (SJL) were studied in detail using bioinformatics and biophysical tools. Homology model of the lectin displayed all the characteristics of the legume lectin monomer and the experimental observations correlated well with the structural inform...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.05.047

    authors： Yadav P,Shahane G,Ramasamy S,Sengupta D,Gaikwad S

    更新日期：2016-10-01 00:00:00

  • Chitosan oligosaccharide-g-linalool polymer as inhibitor of hyaluronidase and collagenase activity.

    abstract：:In this study, chitosan oligosaccharide (COS) was modified by grafting Linalool (Lin) on its backbone to improve its anti-inflammatory activity. By changing the molar ratios of COS to Lin, three different degrees of substitution COS-g-Lin1-3 were prepared. The degrees of substitution of derivatives were 0.65, 0.80 and...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.11.036

    authors： Mao S,Liu X,Xia W

    更新日期：2021-01-01 00:00:00

  • Pectin-blended anionic polysaccharide films for cationic contaminant sorption from water.

    abstract：:Substantial amounts of industrial, agricultural, medical and domestic water worldwide are polluted by different types of contaminants. Removing these contaminants from effluent by adsorbent materials made from abundant, inexpensive polysaccharides is a feasible and promising approach to deal with this problem. In the ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.03.091

    authors： Li M,Buschle-Diller G

    更新日期：2017-08-01 00:00:00

  • High-performance interactive analysis of split aptamer and HIV-1 Tat on multiwall carbon nanotube-modified field-effect transistor.

    abstract：:Interaction between split RNA aptamer and the clinically important target, HIV-1 Tat was investigated on a biosensing surface transduced by functionally choreographed multiwall carbon nanotubes (MWCNTs). Acid oxidation was performed to functionalize MWCNTs with carboxyl functional groups. X-ray photoelectron spectrosc...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.12.066

    authors： Fatin MF,Rahim Ruslinda A,Gopinath SCB,Arshad MKM

    更新日期：2019-03-15 00:00:00

  • The xylose-rich pectins from pea hulls.

    abstract：:The hot acid extract of pea hull, HSP, was rich in galacturonic acid, arabinose and xylose. It was fractionated by copper precipitation followed by ion-exchange chromatography. The copper-soluble fraction represented 26% of HSP and was mostly composed of an arabinan with a low degree of branching, some heteroxylans an...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/s0141-8130(97)00055-x

    authors： Renard CM,Weightman RM,Thibault JF

    更新日期：1997-08-01 00:00:00

  • Production and characterization of hydrophilic and hydrophobic sunflower protein isolate nanofibers by electrospinning method.

    abstract：:In the present study, sunflower protein isolate (SPI) was extracted and applied for production of nanofiber using polyvinyl alcohol (PVA) in different SPI:PVA volume ratios (0:100, 20:80, 40:60, 60:40, 80:20 and 100:0) under two voltages (18 and 23 kV) and two flow rates (0.5 and 0.75 ml/h). Nanofibers with average di...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.07.132

    authors： Shanesazzadeh E,Kadivar M,Fathi M

    更新日期：2018-11-01 00:00:00

  • Doxorubicin-loaded fucoidan capped gold nanoparticles for drug delivery and photoacoustic imaging.

    abstract：:Polymer nanoparticles are emerging as a useful tool for a wide variety of biomedical and therapeutic applications. The present study demonstrates the multifunctional doxorubicin-loaded fucoidan capped gold nanoparticles (DOX-Fu AuNPs) for drug delivery and photoacoustic imaging (PAI). Biocompatible AuNPs were synthesi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.06.007

    authors： Manivasagan P,Bharathiraja S,Bui NQ,Jang B,Oh YO,Lim IG,Oh J

    更新日期：2016-10-01 00:00:00

  • Cellulose extraction from methyltrioctylammonium chloride pretreated sugarcane bagasse and its application.

    abstract：:Cellulose, the most abundant feedstock of chemicals and energy is extracted from various agro-industrial wastes, such as sugarcane bagasse (SB). Pretreatment of SB with ionic liquids improves extraction of cellulose, yet the use of ionic liquid is hindered by its high cost. In this study, cellulose was extracted from ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.09.151

    authors： Ejaz U,Muhammad S,Ali FI,Hashmi IA,Sohail M

    更新日期：2020-12-15 00:00:00

  • Sequestration of toxic congo red dye from aqueous solution using ecofriendly guar gum/ activated carbon nanocomposite.

    abstract：:In the present study, a potential Guar gum/activated carbon nanocomposite as an adsorbent was synthesized and utilized for the sequestration of toxic congo red dye from synthetic wastewater. The nanocomposite was characterized using different techniques such as SEM, EDX, TEM, FTIR and XRD. Various physico-chemical par...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.05.025

    authors： Gupta VK,Agarwal S,Ahmad R,Mirza A,Mittal J

    更新日期：2020-05-07 00:00:00

  • Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis.

    abstract：:Glycosylation possess prominent biological and pharmacological significance in natural product and drug candidate synthesis. The glycosyltransferase YjiC, discovered from Bacillus subtilis (Bs-YjiC), shows potential applications in drug development due to its wide substrate spectrums. In order to elucidate its catalyt...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.10.238

    authors： Liu B,Zhao C,Xiang Q,Zhao N,Luo Y,Bao R

    更新日期：2021-01-01 00:00:00

  • Structure elucidation and properties of different lignins isolated from acorn shell of Quercus variabilis Bl.

    abstract：:Chemical and structure properties of Ethanol lignin (EL), alkali lignin (AL), milled wood lignin (MWL) and cellulase enzymatic lignin (CEL) extracted from acorn shell of Quercus variabilis Bl. was studied by GPC, TG, SEM, FT-IR, 13C NMR, DEPT-135 NMR, 2D-HSQC and functional groups measurement. Results indicated that A...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.09.099

    authors： Zhang Y,Yang L,Wang D,Li D

    更新日期：2018-02-01 00:00:00

  • Interaction of three new tetradentates Schiff bases containing N2O2 donor atoms with calf thymus DNA.

    abstract：:Interaction of 1,3-bis(2-hydroxy-benzylidene)-urea (H2L1), 1,3-bis(2-hydroxy-3-methoxy-benzylidene)-urea (H2L2) and 1,3-bis(2-hydroxy-3-methoxy-benzylidene)-urea nickel(II) (NiL2) with calf-thymus DNA were investigated by UV-vis absorption, fluorescence emission and circular dichroism (CD) spectroscopy as well as cycl...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.03.016

    authors： Ajloo D,Shabanpanah S,Shafaatian B,Ghadamgahi M,Alipour Y,Lashgarbolouki T,Saboury AA

    更新日期：2015-01-01 00:00:00

  • Isolation and characterization of Populus xyloglucan endotransglycosylase/hydrolase (XTH) involved in osmotic stress responses.

    abstract：:Xyloglucan endotransglycosylase/hydrolase (XTH) belongs to the GH16 subfamily of the glycoside hydrolases of carbohydrate active enzymes and plays an important role in the structure and function of plant cell walls. In this study, 11 members of the XTH gene family were cloned from Populus tomentosa. A bioinformatics a...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.11.099

    authors： Jiang Y,Li Y,Lu C,Tang Y,Jiang X,Gai Y

    更新日期：2020-07-15 00:00:00

  • Development of albumin-based nanoparticles for the delivery of abacavir.

    abstract：:The study was designed to prepare and evaluate albumin nanoparticles containing antiviral drug abacavir sulphate. Various batches of albumin nanoparticles containing abacavir sulphate were prepared by desolvation method. The abacavir loaded particles were characterized for their yield, percentage of drug loading, surf...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.09.015

    authors： Wilson B,Paladugu L,Priyadarshini SR,Jenita JJ

    更新日期：2015-11-01 00:00:00

  • Biomaterials based on N,N,N-trimethyl chitosan fibers in wound dressing applications.

    abstract：:In the present work, N,N,N-trimethyl chitosan (TMC) fibers were synthesized successfully and the resulting quaternized materials were characterized by FTIR. The designed TMC fibers with different degree of quaternization achieved high water absorption capability. In antibacterial activity study, TMC fibers showed high...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.02.036

    authors： Zhou Z,Yan D,Cheng X,Kong M,Liu Y,Feng C,Chen X

    更新日期：2016-08-01 00:00:00

  • Structure and hypoglycemic activity of a novel exopolysaccharide of Cordyceps militaris.

    abstract：:A novel neutral exopolysaccharide (EPS-III) was isolated from culture broth of Cordyceps militaris (C. militaris). The EPS-III was a homogeneous polysaccharide with Mw of 1.56 × 103 kDa. The yield of EPS-III from culture broth was 123.2 ± 3.1 mg/L and the sugar content was 93.32 ± 0.87%. The backbone of EPS-III was ma...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.10.207

    authors： Sun H,Yu X,Li T,Zhu Z

    更新日期：2021-01-01 00:00:00

  • α-Glucosidase inhibition by luteolin: kinetics, interaction and molecular docking.

    abstract：:α-Glucosidase is a critical associated enzyme with type 2 diabetes mellitus in humans. Inhibition of α-glucosidase is important due to the potential effect of down regulating glucose absorption in patients. In this study, the inhibitory activity of flavone luteolin on α-glucosidase and their interaction mechanism were...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.12.007

    authors： Yan J,Zhang G,Pan J,Wang Y

    更新日期：2014-03-01 00:00:00

  • Alginate based tamoxifen/metal dual core-folate decorated shell: Nanocomposite targeted therapy for breast cancer via ROS-driven NF-κB pathway modulation.

    abstract：:Breast cancer endocrine resistance prevents unleashing full capabilities of Tamoxifen (TMX), besides TMX off-target side effects on healthy tissue. In this study, we engineered TMX nanocomposite via co-loading it on alginate-based silver nanoparticles and embedding within folic acid-polyethylene glycol surface conjuga...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.12.266

    authors： Ibrahim OM,El-Deeb NM,Abbas H,Elmasry SM,El-Aassar MR

    更新日期：2020-03-01 00:00:00

  • Characterization, release, and antioxidant activity of curcumin-loaded sodium alginate/ZnO hydrogel beads.

    abstract：:In this study, we fabricated a series of novel sodium alginate/ZnO hydrogel beads to optimize the release profile of curcumin (Cur) and to avoid the burst release associated with pure hydrogels, which were used to mitigate the weaknesses of Cur, such as rapid physiological clearance and sensitivity to ultraviolet (UV)...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.10.121

    authors： Wang H,Gong X,Guo X,Liu C,Fan YY,Zhang J,Niu B,Li W

    更新日期：2019-01-01 00:00:00

  • Date palm (Phoenix dactylifera L.) fruit's polyphenols as potential inhibitors for human amylin fibril formation and toxicity in type 2 diabetes.

    abstract：BACKGROUND:β-Cell death is the key feature of type 2 diabetes mellitus (T2DM). The misfolding of human Islet Amyloid Polypeptide (hIAPP) is regarded as one of the causative factors of T2DM. Recent studies suggested that a diet based on date fruits presents various health benefits, as these fruits are naturally enriched...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.08.080

    authors： Chaari A,Abdellatif B,Nabi F,Khan RH

    更新日期：2020-12-01 00:00:00