Abstract:
:This study examines the regulation of thyroid activity in adult rough-skinned newts, Taricha granulosa. Aquatic, breeding-condition newts were hypophysectomized and were injected for 23 days with the mammalian adenohypophysial hormones: ACTH, PRL, and GH. During a fourth week of treatment, these newts also received TSH. Plasma T4 concentrations were lower in hypophysectomized newts than in sham-hypophysectomized newts 23 days after surgery. Both ACTH and PRL increased T4 titers above these in saline-injected control newts; GH alone had no effect. TSH effectively increased the plasma T4 concentrations in newts from all five groups. GH, and possibly PRL, depressed the response to TSH. Plasma T4 concentration was positively correlated with body fluid loss, suggesting that hormone concentration/dilution effects may occur generally in animals such as these that undergo substantial seasonal changes in degree of hydration.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Specker JL,Brown PS,Brown SCdoi
10.1016/0016-6480(85)90385-5subject
Has Abstractpub_date
1985-08-01 00:00:00pages
326-31issue
2eissn
0016-6480issn
1095-6840journal_volume
59pub_type
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
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