Abstract:
:Helicobacter pylori is the most abundant bacterium in the gastric epithelium, and its presence has been associated with the risk of developing gastric cancer. As of 15 years ago, no other bacteria were associated with gastric epithelial colonization; but thanks to new methodologies, many other non-H. pylori bacteria have been identified. It is possible that non-H. pylori may have a significant role in the development of gastric cancer. Here, we discuss the specific role of H. pylori as a potential trigger for events that may be conducive to gastric cancer, and consider whether or not the rest of the gastric microbiota represent an additional risk in the development of this disease.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Li J,Perez Perez GIdoi
10.3390/ijms19051353subject
Has Abstractpub_date
2018-05-03 00:00:00issue
5issn
1422-0067pii
ijms19051353journal_volume
19pub_type
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journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms13077902
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journal_title:International journal of molecular sciences
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abstract::Selectively targeted nanoscale drug delivery systems have recently emerged as promising intravenously therapeutic option for most chronic joint diseases. Here, a newly synthetized dodecapeptide (GE11)-polylactide-co-glycolide (PLGA)-based conjugate was used to prepare smart nanoparticles (NPs) intended for intra-artic...
journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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更新日期:2018-05-15 00:00:00
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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更新日期:2017-10-25 00:00:00
abstract::Eukaryotic cells express a large variety of RNA binding proteins (RBPs), with diverse affinities and specificities towards target RNAs. These proteins play a crucial role in almost every aspect of RNA biogenesis, expression and function. The heterogeneous nuclear ribonucleoproteins (hnRNPs) are a complex and diverse f...
journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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更新日期:2019-10-11 00:00:00
abstract::Zinc finger protein 554 (ZNF554), a member of the Krüppel-associated box domain zinc finger protein subfamily, is predominantly expressed in the brain and placenta in humans. Recently, we unveiled that ZNF554 regulates trophoblast invasion during placentation and its decreased expression leads to the early pathogenesi...
journal_title:International journal of molecular sciences
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abstract::Activated carbon honeycomb-monoliths with different textural properties were prepared by chemical activation of African palm shells with H(3)PO(4), ZnCl(2) and CaCl(2) aqueous solutions of various concentrations. The adsorbents obtained were characterized by N(2) adsorption at 77 K, and their carbon dioxide adsorption...
journal_title:International journal of molecular sciences
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doi:10.3390/ijms13078388
更新日期:2012-01-01 00:00:00
abstract::The concentration of five soil heavy metals (Pb, Co, Cr, Cu, Hg) was measured in forty sampling sites in central Transylvania, Romania, regions known as centres of pollution due to the chemical and metallurgical activities. The soil samples were collected from locations where the ground is not sliding and the probabil...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms9040434
更新日期:2008-04-01 00:00:00
abstract::Curcumin diglutaric acid (CurDG), an ester prodrug of curcumin, has the potential to be developed as an anti-inflammatory agent due to its improved solubility and stability. In this study, the anti-inflammatory effects of CurDG were evaluated. The effects of CurDG on inflammatory mediators were evaluated in LPS-stimul...
journal_title:International journal of molecular sciences
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abstract::MicroRNAs (miRNAs) play key roles in plant reproduction. However, knowledge on microRNAome analysis in autotetraploid rice is rather limited. Here, high-throughput sequencing technology was employed to analyze miRNAomes during pollen development in diploid and polyploid rice. A total of 172 differentially expressed mi...
journal_title:International journal of molecular sciences
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doi:10.3390/ijms17040499
更新日期:2016-04-12 00:00:00
abstract::The genetic basis of the wide variation for nutritional traits in Brassica rapa is largely unknown. A new Recombinant Inbred Line (RIL) population was profiled using High Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) analysis to detect quantitative trait loci (QTLs) controlling seed toc...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms140815561
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abstract::The Mexican axolotl salamander (Ambystoma mexicanum) is one member of a select group of vertebrate animals that have retained the amazing ability to regenerate multiple body parts. In addition to being an important model system for regeneration, the axolotl has also contributed extensively to studies of basic developm...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms160922046
更新日期:2015-09-11 00:00:00
abstract::Molecular etiology of thyroid cancers has been widely studied, and several molecular alterations have been identified mainly associated with follicular and papillary histotypes. However, the molecular bases of the complex pathogenesis of thyroid carcinomas remain poorly understood. HOX genes regulate normal embryonic ...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms141121727
更新日期:2013-11-01 00:00:00
abstract::Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of irreversible blindness in the developed world. DR arises as the result of prolonged hyperglycemia and is characterized by leaky retinal vasculature, retinal ischemia, retinal inflammation, angiogenesis, and neovascularization. Th...
journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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doi:10.3390/ijms151121270
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
pub_type: 杂志文章
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更新日期:2020-07-01 00:00:00
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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更新日期:2020-08-10 00:00:00
abstract::Phytochelatins (PCs) play an important role in detoxification of heavy metals in plants. PCs are synthesized from glutathione by phytochelatin synthase (PCS), a dipeptidyltransferase. Sesbania rostrata is a tropical legume plant that can tolerate high concentrations of Cd and Zn. In this study, the S. rostrata PCS gen...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
doi:10.3390/ijms10083269
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21218229
更新日期:2020-11-03 00:00:00
abstract::The Duchenne muscular dystrophy (DMD) gene has a complex expression pattern regulated by multiple tissue-specific promoters and by alternative splicing (AS) of the resulting transcripts. Here, we used an RNAi-based approach coupled with DMD-targeted RNA-seq to identify RNA-binding proteins (RBPs) that regulate splicin...
journal_title:International journal of molecular sciences
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doi:10.3390/ijms21207803
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journal_title:International journal of molecular sciences
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doi:10.3390/ijms21020460
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms21238989
更新日期:2020-11-26 00:00:00