Highly durable, coking and sulfur tolerant, fuel-flexible protonic ceramic fuel cells.

abstract：:Polar molecules have a rich internal structure and long-range dipole-dipole interactions, making them useful for quantum-controlled applications and fundamental investigations. Their potential fully unfolds at ultracold temperatures, where various effects are predicted in many-body physics, quantum information science...

journal_title：Nature

authors： Zeppenfeld M,Englert BG,Glöckner R,Prehn A,Mielenz M,Sommer C,van Buuren LD,Motsch M,Rempe G

更新日期：2012-11-22 00:00:00

abstract：:The isolation of a mutant adenovirus carrying an insertion of cellular DNA has led to the identification of a new family of human repetitive sequences, which are found tandemly arranged in the genome. The sequence of the viral insert resembles that of eukaryotic transposable elements. ...

journal_title：Nature

authors： Shimizu Y,Yoshida K,Ren CS,Fujinaga K,Rajagopalan S,Chinnadurai G

更新日期：1983-04-14 00:00:00

abstract：:There has been much interest in the biochemical and biophysical processes that couple extracellular signals to alterations in gene expression. While many early events associated with the treatment of cells with growth factors have been described (for example, ion flux and protein phosphorylation), it has proved diffic...

journal_title：Nature

authors： Morgan JI,Curran T

更新日期：1986-08-07 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, is characterized by elevated glycogen levels and fat deposition. These consistent metabolic alterations are associated with normoxic stabilization of hypoxia-inducible factors (HIFs) secondary to von Hippel-Lindau (VHL) mutations that occu...

journal_title：Nature

authors： Li B,Qiu B,Lee DS,Walton ZE,Ochocki JD,Mathew LK,Mancuso A,Gade TP,Keith B,Nissim I,Simon MC

更新日期：2014-09-11 00:00:00

abstract：:Homologous recombination is a molecular process that has multiple important roles in DNA metabolism, both for DNA repair and genetic variation in all forms of life. Generally, homologous recombination involves the exchange of genetic information between two identical or nearly identical DNA molecules; however, homolog...

journal_title：Nature

authors： Keskin H,Shen Y,Huang F,Patel M,Yang T,Ashley K,Mazin AV,Storici F

更新日期：2014-11-20 00:00:00

abstract：:Despite active transport into Earth's mantle, water has been present on our planet's surface for most of geological time. Yet water disappeared from the Martian surface soon after its formation. Although some of the water on Mars was lost to space via photolysis following the collapse of the planet's magnetic field, t...

journal_title：Nature

authors： Wade J,Dyck B,Palin RM,Moore JDP,Smye AJ

更新日期：2017-12-20 00:00:00

abstract：:Only about 1% of human XO conceptuses survive to birth and these usually have the characteristics of Turner's syndrome, with a complex and variable phenotype including short stature, gonadal dysgenesis and anatomical defects. Both the embryonic lethality and Turner's syndrome are thought to be due to monosomy for a ge...

journal_title：Nature

authors： Ashworth A,Rastan S,Lovell-Badge R,Kay G

更新日期：1991-05-30 00:00:00

abstract：:The Earth's convecting upper mantle can be viewed as comprising three main reservoirs, beneath the Pacific, Atlantic and Indian oceans. Because of the uneven global distribution and migration of ridges and subduction zones, the surface area of the Pacific reservoir is at present contracting at about 0.6 km2 x y(r-1), ...

journal_title：Nature

authors： Pearce JA,Leat PT,Barker PF,Millar IL

更新日期：2001-03-22 00:00:00

abstract：:The hypothesis that animal population dynamics may be synchronized by climate is highly relevant in the context of climate change because it suggests that several populations might respond simultaneously to climatic trends if their dynamics are entrained by environmental correlation. The dynamics of many species throu...

journal_title：Nature

authors： Post E,Forchhammer MC

更新日期：2002-11-14 00:00:00

abstract：:Where continental plates break apart, slip along multiple normal faults provides the required space for the Earth's crust to thin and subside. After initial rifting, however, the displacement on normal faults observed at the sea floor seems not to match the inferred extension. Here we show that crustal thinning can be...

journal_title：Nature

authors： Lavier LL,Manatschal G

更新日期：2006-03-16 00:00:00

abstract：:Monoclonal antibodies can now be genetically engineered and endowed with new properties. In the future, gene technology could enable antigen-binding fragments to be made by exploiting repertoires of variable domain genes derived from immunized animals and expressed in bacteria. How readily can this approach be extende...

journal_title：Nature

authors： Winter G,Milstein C

更新日期：1991-01-24 00:00:00

abstract：:The discovery of intervening sequences (introns) in DNA led Gilbert and Tonegawa to suggest that a new protein could have been produced by bringing together certain segments of pre-existing ones. However, Blake argued that if DNA was so organized that coding sequences (exons) correspond to structural as well as functi...

journal_title：Nature

authors： Go M

更新日期：1981-05-07 00:00:00

abstract：:In this Letter, the top structure of the right panel of Fig. 1a should be that of cis-9-octadecenoic acid, not trans-9-octadecenoic acid. Please see the accompanying Author Correction. This error has not been corrected online. ...

journal_title：Nature

authors： Yang Z,Wei J,Sobolev YI,Grzybowski BA

更新日期：2019-03-01 00:00:00

abstract：:The carotid body type I cell contains amines and has features, both morphological and cytochemical, which indicate that it may also produce a peptide. Many regulatory peptides are now known to be present in both central and peripheral tissues. In the periphery these neuropeptides occur in both classical endocrine (APU...

journal_title：Nature

authors： Wharton J,Polak JM,Pearse AG,McGregor GP,Bryant MG,Bloom SR,Emson PC,Bisgard GE,Will JA

更新日期：1980-03-20 00:00:00

abstract：:Evolutionary adaptation can be rapid and potentially help species counter stressful conditions or realize ecological opportunities arising from climate change. The challenges are to understand when evolution will occur and to identify potential evolutionary winners as well as losers, such as species lacking adaptive c...

journal_title：Nature

authors： Hoffmann AA,Sgrò CM

更新日期：2011-02-24 00:00:00

abstract：:The folding of newly synthesized proteins to the native state is a major challenge within the crowded cellular environment, as non-productive interactions can lead to misfolding, aggregation and degradation1. Cells cope with this challenge by coupling synthesis with polypeptide folding and by using molecular chaperone...

journal_title：Nature

authors： Shiber A,Döring K,Friedrich U,Klann K,Merker D,Zedan M,Tippmann F,Kramer G,Bukau B

更新日期：2018-09-01 00:00:00

abstract：:Nuclear magic numbers correspond to fully occupied energy shells of protons or neutrons inside atomic nuclei. Doubly magic nuclei, with magic numbers for both protons and neutrons, are spherical and extremely rare across the nuclear landscape. Although the sequence of magic numbers is well established for stable nucle...

journal_title：Nature

authors： Taniuchi R,Santamaria C,Doornenbal P,Obertelli A,Yoneda K,Authelet G,Baba H,Calvet D,Château F,Corsi A,Delbart A,Gheller JM,Gillibert A,Holt JD,Isobe T,Lapoux V,Matsushita M,Menéndez J,Momiyama S,Motobayashi T,Nii

更新日期：2019-05-01 00:00:00

abstract：:Thermoelectric energy harvesting-the transformation of waste heat into useful electricity-is of great interest for energy sustainability. The main obstacle is the low thermoelectric efficiency of materials for converting heat to electricity, quantified by the thermoelectric figure of merit, ZT. The best available n-ty...

journal_title：Nature

authors： Rhyee JS,Lee KH,Lee SM,Cho E,Kim SI,Lee E,Kwon YS,Shim JH,Kotliar G

更新日期：2009-06-18 00:00:00

abstract：:The primary structure of the poliovirus genome has been determined. The RNA molecule is 7,433 nucleotides long, polyadenylated at the 3' terminus, and covalently linked to a small protein (VPg) at the 5' terminus. An open reading frame of 2,207 consecutive triplets spans over 89% of the nucleotide sequence and codes f...

journal_title：Nature

authors： Kitamura N,Semler BL,Rothberg PG,Larsen GR,Adler CJ,Dorner AJ,Emini EA,Hanecak R,Lee JJ,van der Werf S,Anderson CW,Wimmer E

更新日期：1981-06-18 00:00:00

abstract：:Polymer electrolyte membrane fuel cells (PEMFCs) running on hydrogen are attractive alternative power supplies for a range of applications, with in situ release of the required hydrogen from a stable liquid offering one way of ensuring its safe storage and transportation before use. The use of methanol is particularly...

journal_title：Nature

authors： Lin L,Zhou W,Gao R,Yao S,Zhang X,Xu W,Zheng S,Jiang Z,Yu Q,Li YW,Shi C,Wen XD,Ma D

更新日期：2017-04-06 00:00:00

abstract：:An emerging concept in the field of cancer biology is that a rare population of 'tumour stem cells' exists among the heterogeneous group of cells that constitute a tumour. This concept, best described with human leukaemia, indicates that stem cell function (whether normal or neoplastic) might be defined by a common se...

journal_title：Nature

authors： Lessard J,Sauvageau G

更新日期：2003-05-15 00:00:00

abstract：:Gene targeting in mouse embryo-derived stem cells has been used to disrupt the homeobox gene hox-1.5. Mice heterozygous at the hox-1.5 locus appear normal, whereas hox-1.5-/hox-1.5- mice die at or shortly after birth. These homozygotes are athymic, aparathyroid, have reduced thyroid and submaxillary tissue and exhibit...

journal_title：Nature

authors： Chisaka O,Capecchi MR

更新日期：1991-04-11 00:00:00

abstract：:The distribution of geochemical species in the Earth's interior is largely controlled by fractional melting and crystallization processes that are intimately linked to the thermal state and evolution of the mantle. The existence of patches of dense partial melt at the base of the Earth's mantle, together with estimate...

journal_title：Nature

authors： Labrosse S,Hernlund JW,Coltice N

更新日期：2007-12-06 00:00:00

abstract：:Growth factors raise intracellular pH (pHi) by stimulating Na+/H+ exchange in the absence of HCO3-. In mutant cells that lack the Na+/H+ exchange activity, this alkalinization does not occur, and the cells do not proliferate without artificial elevation of pHi. It has therefore been widely suggested that an early pHi ...

journal_title：Nature

authors： Ganz MB,Boyarsky G,Sterzel RB,Boron WF

更新日期：1989-02-16 00:00:00

abstract：:Regular mesoporous oxide materials have been widely studied and have a range of potential applications, such as catalysis, absorption and separation. They are not generally considered for their optical and electronic properties. Elemental semiconductors with nanopores running through them represent a different form of...

journal_title：Nature

authors： Armatas GS,Kanatzidis MG

更新日期：2006-06-29 00:00:00

abstract：:Quantum light is characterized by distinctive statistical distributions that are possible only because of quantum mechanical effects. For example, single photons and correlated photon pairs exhibit photon number distributions with variance lower than classically allowed limits. This enables high-fidelity transmission ...

journal_title：Nature

authors： Mittal S,Goldschmidt EA,Hafezi M

更新日期：2018-09-01 00:00:00

abstract：:Insulin-dependent diabetes is a complex multifactorial disorder characterized by loss or dysfunction of β-cells. Pancreatic β-cells differ in size, glucose responsiveness, insulin secretion and precursor cell potential; understanding the mechanisms that underlie this functional heterogeneity might make it possible to ...

journal_title：Nature

authors： Bader E,Migliorini A,Gegg M,Moruzzi N,Gerdes J,Roscioni SS,Bakhti M,Brandl E,Irmler M,Beckers J,Aichler M,Feuchtinger A,Leitzinger C,Zischka H,Wang-Sattler R,Jastroch M,Tschöp M,Machicao F,Staiger H,Häring HU,Chme

更新日期：2016-07-21 00:00:00

abstract：:Haemoglobin is the prototype of an allosteric protein in which cooperative behaviour depends on interaction between unlike subunits. Here we present haematological and biochemical evidence that electrostatic interactions are an important determinant of haemoglobin assembly. Individuals heterozygous for positively char...

journal_title：Nature

authors： Bunn HF,McDonald MJ

更新日期：1983-12-01 00:00:00

abstract：:The partial amino-acid sequence of purified human transforming growth factor-beta (TGF-beta) was used to identify a series of cDNA clones encoding the protein. The cDNA sequence indicates that the 112-amino acid monomeric form of the natural TGF-beta homodimer is derived proteolytically from a much longer precursor po...

journal_title：Nature

authors： Derynck R,Jarrett JA,Chen EY,Eaton DH,Bell JR,Assoian RK,Roberts AB,Sporn MB,Goeddel DV

更新日期：1985-08-22 00:00:00

abstract：:A long-standing goal of artificial intelligence is an algorithm that learns, tabula rasa, superhuman proficiency in challenging domains. Recently, AlphaGo became the first program to defeat a world champion in the game of Go. The tree search in AlphaGo evaluated positions and selected moves using deep neural networks....

journal_title：Nature

authors： Silver D,Schrittwieser J,Simonyan K,Antonoglou I,Huang A,Guez A,Hubert T,Baker L,Lai M,Bolton A,Chen Y,Lillicrap T,Hui F,Sifre L,van den Driessche G,Graepel T,Hassabis D

更新日期：2017-10-18 00:00:00