Highly durable, coking and sulfur tolerant, fuel-flexible protonic ceramic fuel cells.


:Protonic ceramic fuel cells, like their higher-temperature solid-oxide fuel cell counterparts, can directly use both hydrogen and hydrocarbon fuels to produce electricity at potentially more than 50 per cent efficiency1,2. Most previous direct-hydrocarbon fuel cell research has focused on solid-oxide fuel cells based on oxygen-ion-conducting electrolytes, but carbon deposition (coking) and sulfur poisoning typically occur when such fuel cells are directly operated on hydrocarbon- and/or sulfur-containing fuels, resulting in severe performance degradation over time3-6. Despite studies suggesting good performance and anti-coking resistance in hydrocarbon-fuelled protonic ceramic fuel cells2,7,8, there have been no systematic studies of long-term durability. Here we present results from long-term testing of protonic ceramic fuel cells using a total of 11 different fuels (hydrogen, methane, domestic natural gas (with and without hydrogen sulfide), propane, n-butane, i-butane, iso-octane, methanol, ethanol and ammonia) at temperatures between 500 and 600 degrees Celsius. Several cells have been tested for over 6,000 hours, and we demonstrate excellent performance and exceptional durability (less than 1.5 per cent degradation per 1,000 hours in most cases) across all fuels without any modifications in the cell composition or architecture. Large fluctuations in temperature are tolerated, and coking is not observed even after thousands of hours of continuous operation. Finally, sulfur, a notorious poison for both low-temperature and high-temperature fuel cells, does not seem to affect the performance of protonic ceramic fuel cells when supplied at levels consistent with commercial fuels. The fuel flexibility and long-term durability demonstrated by the protonic ceramic fuel cell devices highlight the promise of this technology and its potential for commercial application.






Duan C,Kee RJ,Zhu H,Karakaya C,Chen Y,Ricote S,Jarry A,Crumlin EJ,Hook D,Braun R,Sullivan NP,O'Hayre R




Has Abstract


2018-05-01 00:00:00
















  • Terminal pattern elements in Drosophila embryo induced by the torso-like protein.

    abstract::The genes torso (tor) and torso-like (tsl) are two of the Drosophila maternal group genes implicated in a receptor tyrosine kinase signalling pathway that specifies terminal cell fate (reviewed in ref. 3). Loss-of-function mutations in these loci cause an identical phenotype in which pattern elements from the anterior...


    pub_type: 杂志文章


    authors: Martin JR,Raibaud A,Ollo R

    更新日期:1994-02-24 00:00:00

  • Clinical improvement in psoriasis with specific targeting of interleukin-23.

    abstract::Psoriasis is a chronic inflammatory skin disorder that affects approximately 2-3% of the population worldwide and has severe effects on patients' physical and psychological well-being. The discovery that psoriasis is an immune-mediated disease has led to more targeted, effective therapies; recent advances have focused...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Kopp T,Riedl E,Bangert C,Bowman EP,Greisenegger E,Horowitz A,Kittler H,Blumenschein WM,McClanahan TK,Marbury T,Zachariae C,Xu D,Hou XS,Mehta A,Zandvliet AS,Montgomery D,van Aarle F,Khalilieh S

    更新日期:2015-05-14 00:00:00

  • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death.

    abstract::Current ideas about the dependence of neurons on target-derived growth factors were formulated on the basis of experiments involving neurons with projections to the periphery. Nerve growth factor (NGF) and recently identified members of the NGF family of neuronal growth factors, known as neurotrophins, are thought to ...


    pub_type: 杂志文章


    authors: Yan Q,Elliott J,Snider WD

    更新日期:1992-12-24 00:00:00

  • Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.

    abstract::Human apolipoprotein E has three isoforms: APOE2, APOE3 and APOE4. APOE4 is a major genetic risk factor for Alzheimer's disease and is associated with Down's syndrome dementia and poor neurological outcome after traumatic brain injury and haemorrhage. Neurovascular dysfunction is present in normal APOE4 carriers and i...


    pub_type: 杂志文章


    authors: Bell RD,Winkler EA,Singh I,Sagare AP,Deane R,Wu Z,Holtzman DM,Betsholtz C,Armulik A,Sallstrom J,Berk BC,Zlokovic BV

    更新日期:2012-05-16 00:00:00

  • Continuing Colorado plateau uplift by delamination-style convective lithospheric downwelling.

    abstract::The Colorado plateau is a large, tectonically intact, physiographic province in the southwestern North American Cordillera that stands at ∼1,800-2,000 m elevation and has long been thought to be in isostatic equilibrium. The origin of these high elevations is unclear because unlike the surrounding provinces, which hav...


    pub_type: 杂志文章


    authors: Levander A,Schmandt B,Miller MS,Liu K,Karlstrom KE,Crow RS,Lee CT,Humphreys ED

    更新日期:2011-04-28 00:00:00

  • Asymmetric relationships between homosynaptic long-term potentiation and heterosynaptic long-term depression.

    abstract::All synaptically-based neuropsychological theories of learning postulate that there are changes resulting from neural activity which are long-lasting and confined to specific sets of synapses. In the past decade a form of synaptic strengthening known as long-term potentiation (LTP) has been found which results from hi...


    pub_type: 杂志文章


    authors: Abraham WC,Goddard GV

    更新日期:1983-10-20 00:00:00

  • Neural circuitry linking mating and egg laying in Drosophila females.

    abstract::Mating and egg laying are tightly cooordinated events in the reproductive life of all oviparous females. Oviposition is typically rare in virgin females but is initiated after copulation. Here we identify the neural circuitry that links egg laying to mating status in Drosophila melanogaster. Activation of female-speci...


    pub_type: 杂志文章


    authors: Wang F,Wang K,Forknall N,Patrick C,Yang T,Parekh R,Bock D,Dickson BJ

    更新日期:2020-03-01 00:00:00

  • Gigantism in mice lacking suppressor of cytokine signalling-2.

    abstract::Suppressor of cytokine signalling-2 (SOCS-2) is a member of the suppressor of cytokine signalling family, a group of related proteins implicated in the negative regulation of cytokine action through inhibition of the Janus kinase (JAK) signal transducers and activators of transcription (STAT) signal-transduction pathw...


    pub_type: 杂志文章


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  • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.

    abstract::Epigenetic pathways can regulate gene expression by controlling and interpreting chromatin modifications. Cancer cells are characterized by altered epigenetic landscapes, and commonly exploit the chromatin regulatory machinery to enforce oncogenic gene expression programs. Although chromatin alterations are, in princi...


    pub_type: 杂志文章


    authors: Zuber J,Shi J,Wang E,Rappaport AR,Herrmann H,Sison EA,Magoon D,Qi J,Blatt K,Wunderlich M,Taylor MJ,Johns C,Chicas A,Mulloy JC,Kogan SC,Brown P,Valent P,Bradner JE,Lowe SW,Vakoc CR

    更新日期:2011-08-03 00:00:00

  • Peptide growth factors are multifunctional.

    abstract::The actions of many peptide growth factors include both stimulation and inhibition of cell proliferation, as well as effects unrelated to the control of cell growth. One peptide can have both stimulatory and inhibitory activity in a single cell, depending on the context of the other signal molecules present. ...


    pub_type: 杂志文章,评审


    authors: Sporn MB,Roberts AB

    更新日期:1988-03-17 00:00:00

  • A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.

    abstract::Immunomodulatory drugs bind to cereblon (CRBN) to confer differentiated substrate specificity on the CRL4(CRBN) E3 ubiquitin ligase. Here we report the identification of a new cereblon modulator, CC-885, with potent anti-tumour activity. The anti-tumour activity of CC-885 is mediated through the cereblon-dependent ubi...


    pub_type: 杂志文章


    authors: Matyskiela ME,Lu G,Ito T,Pagarigan B,Lu CC,Miller K,Fang W,Wang NY,Nguyen D,Houston J,Carmel G,Tran T,Riley M,Nosaka L,Lander GC,Gaidarova S,Xu S,Ruchelman AL,Handa H,Carmichael J,Daniel TO,Cathers BE,Lopez-Gi

    更新日期:2016-07-14 00:00:00

  • Tissue-specific activation of a cloned alpha-fetoprotein gene during differentiation of a transfected embryonal carcinoma cell line.

    abstract::To identify cis-acting DNA elements involved in the activation of the alpha-fetoprotein gene during differentiation, modified copies of the gene were introduced into murine F9 embryonal carcinoma cells. The differentiation of the transformants to either parietal or visceral endoderm was accompanied by induction of the...


    pub_type: 杂志文章


    authors: Scott RW,Vogt TF,Croke ME,Tilghman SM

    更新日期:1984-08-16 00:00:00

  • Quantum simulation of antiferromagnetic spin chains in an optical lattice.

    abstract::Understanding exotic forms of magnetism in quantum mechanical systems is a central goal of modern condensed matter physics, with implications for systems ranging from high-temperature superconductors to spintronic devices. Simulating magnetic materials in the vicinity of a quantum phase transition is computationally i...


    pub_type: 杂志文章


    authors: Simon J,Bakr WS,Ma R,Tai ME,Preiss PM,Greiner M

    更新日期:2011-04-21 00:00:00

  • Androgenetic haploid embryonic stem cells produce live transgenic mice.

    abstract::Haploids and double haploids are important resources for studying recessive traits and have large impacts on crop breeding, but natural haploids are rare in animals. Mammalian haploids are restricted to germline cells and are occasionally found in tumours with massive chromosome loss. Recent success in establishing ha...


    pub_type: 杂志文章


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    更新日期:2012-10-18 00:00:00

  • Demonstration by genetic suppression of interaction of GroE products with many proteins.

    abstract::The way in which proteins attain and maintain their final form is of fundamental importance. Recent work has focused on the role of a set of ubiquitous proteins, termed chaperonins, in the assembly of phage and multisubunit proteins. The range of chaperonin action is unknown; they could interact with most cellular pol...


    pub_type: 杂志文章


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    更新日期:1989-11-23 00:00:00

  • Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity.

    abstract::The protein TFIIB is a general transcription initiation factor that interacts with a promoter complex (D.DNA) containing the TATA-binding subunit (TFIID tau, or TBP) of TFIID to facilitate subsequent interaction with RNA polymerase II (ref. 2) through the associated TFIIF (ref. 3). The potential bridging function of T...


    pub_type: 杂志文章


    authors: Hisatake K,Roeder RG,Horikoshi M

    更新日期:1993-06-24 00:00:00

  • Optogenetic dissection of a behavioural module in the vertebrate spinal cord.

    abstract::Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic motor commands for rhythmic movements. In vertebrates, the excitatory synaptic drive for inducing the spinal CPG can originate from either supraspinal glutamatergic inputs or from within the spinal cord. Here we identi...


    pub_type: 杂志文章


    authors: Wyart C,Del Bene F,Warp E,Scott EK,Trauner D,Baier H,Isacoff EY

    更新日期:2009-09-17 00:00:00

  • Transient increase in obese gene expression after food intake or insulin administration.

    abstract::Obesity is a disorder of energy balance, indicating a chronic disequilibrium between energy intake and expenditure. Recently, the mouse ob gene, and subsequently its human and rat homologues, have been cloned. The ob gene product, leptin, is expressed exclusively in adipose tissue, and appears to be a signalling facto...


    pub_type: 杂志文章


    authors: Saladin R,De Vos P,Guerre-Millo M,Leturque A,Girard J,Staels B,Auwerx J

    更新日期:1995-10-12 00:00:00

  • New deep-sea species of Xenoturbella and the position of Xenacoelomorpha.

    abstract::The discovery of four new Xenoturbella species from deep waters of the eastern Pacific Ocean is reported here. The genus and two nominal species were described from the west coast of Sweden, but their taxonomic placement remains unstable. Limited evidence placed Xenoturbella with molluscs, but the tissues can be conta...


    pub_type: 杂志文章


    authors: Rouse GW,Wilson NG,Carvajal JI,Vrijenhoek RC

    更新日期:2016-02-04 00:00:00

  • The avian Z-linked gene DMRT1 is required for male sex determination in the chicken.

    abstract::Sex in birds is chromosomally based, as in mammals, but the sex chromosomes are different and the mechanism of avian sex determination has been a long-standing mystery. In the chicken and all other birds, the homogametic sex is male (ZZ) and the heterogametic sex is female (ZW). Two hypotheses have been proposed for t...


    pub_type: 杂志文章


    authors: Smith CA,Roeszler KN,Ohnesorg T,Cummins DM,Farlie PG,Doran TJ,Sinclair AH

    更新日期:2009-09-10 00:00:00

  • Developmental genetics of vertebrate glial-cell specification.

    abstract::Oligodendrocytes and astrocytes are macroglial cells of the vertebrate central nervous system. These cells have diverse roles in the maintenance of neurological function. In the embryo, the genetic mechanisms that underlie the specification of macroglial precursors in vivo appear strikingly similar to those that regul...


    pub_type: 杂志文章,评审


    authors: Rowitch DH,Kriegstein AR

    更新日期:2010-11-11 00:00:00

  • Rapid regulation of steroidogenesis by mitochondrial protein import.

    abstract::Most mitochondrial proteins are synthesized on cytoplasmic ribosomes and imported into mitochondria. The imported proteins are directed to one of four submitochondrial compartments--the outer mitochondrial membrane, the inner mitochondrial membrane, the intramembraneous space, or the matrix--where the protein then fun...


    pub_type: 杂志文章


    authors: Bose HS,Lingappa VR,Miller WL

    更新日期:2002-05-02 00:00:00

  • Focus formation in rat fibroblasts exposed to a tumour promoter after transfer of polyoma plt and myc oncogenes.

    abstract::The gene encoding the large-T protein of polyoma virus (plt), the E1A genes of adenoviruses, the viral myc gene (v-myc) or rearranged forms of the cellular c-myc gene confer on rat embryo fibroblast (REF) cells in primary culture a series of new properties ('immortality', reduced serum requirement and sensitivity to t...


    pub_type: 杂志文章


    authors: Connan G,Rassoulzadegan M,Cuzin F

    更新日期:1985-03-21 00:00:00

  • Highly siderophile elements in Earth's mantle as a clock for the Moon-forming impact.

    abstract::According to the generally accepted scenario, the last giant impact on Earth formed the Moon and initiated the final phase of core formation by melting Earth's mantle. A key goal of geochemistry is to date this event, but different ages have been proposed. Some argue for an early Moon-forming event, approximately 30 m...


    pub_type: 杂志文章


    authors: Jacobson SA,Morbidelli A,Raymond SN,O'Brien DP,Walsh KJ,Rubie DC

    更新日期:2014-04-03 00:00:00

  • Evolutionary genomics: codon bias and selection on single genomes.

    abstract::The idea that natural selection on genes might be detected using only a single genome has been put forward by Plotkin and colleagues, who present a method that they claim can detect selection without the need for comparative data and which, if correct, would confer greater power of analysis with less information. Here...


    pub_type: 评论,杂志文章


    authors: Hahn MW,Mezey JG,Begun DJ,Gillespie JH,Kern AD,Langley CH,Moyle LC

    更新日期:2005-01-20 00:00:00

  • Molecular analysis of spontaneous somatic mutants.

    abstract::Eukaryotic structural gene mutations occurring spontaneously in a mouse myeloma cell line offer the opportunity to study somatic mutation in animal cells at the molecular level. Studies on the myeloma protein and on mRNA have enabled us to characterise four such mutants representing four different mutation mechanisms....


    pub_type: 杂志文章,评审


    authors: Adetugbo K,Milstein C,Secher DS

    更新日期:1977-01-27 00:00:00

  • Sisyphus cooling of electrically trapped polyatomic molecules.

    abstract::Polar molecules have a rich internal structure and long-range dipole-dipole interactions, making them useful for quantum-controlled applications and fundamental investigations. Their potential fully unfolds at ultracold temperatures, where various effects are predicted in many-body physics, quantum information science...


    pub_type: 杂志文章


    authors: Zeppenfeld M,Englert BG,Glöckner R,Prehn A,Mielenz M,Sommer C,van Buuren LD,Motsch M,Rempe G

    更新日期:2012-11-22 00:00:00

  • Two-million-year-old snapshots of atmospheric gases from Antarctic ice.

    abstract::Over the past eight hundred thousand years, glacial-interglacial cycles oscillated with a period of one hundred thousand years ('100k world'1). Ice core and ocean sediment data have shown that atmospheric carbon dioxide, Antarctic temperature, deep ocean temperature, and global ice volume correlated strongly with each...


    pub_type: 杂志文章


    authors: Yan Y,Bender ML,Brook EJ,Clifford HM,Kemeny PC,Kurbatov AV,Mackay S,Mayewski PA,Ng J,Severinghaus JP,Higgins JA

    更新日期:2019-10-01 00:00:00

  • Dynamic cortical activity in the human brain reveals motor equivalence.

    abstract::That animals and humans can accomplish the same goal using different effectors and different goals using the same effectors attests to the remarkable flexibility of the central nervous system. This phenomenon has been termed 'motor equivalence', an example being the writing of a name with a pencil held between the toe...


    pub_type: 杂志文章


    authors: Kelso JA,Fuchs A,Lancaster R,Holroyd T,Cheyne D,Weinberg H

    更新日期:1998-04-23 00:00:00

  • A distance to the Large Magellanic Cloud that is precise to one per cent.

    abstract::In the era of precision cosmology, it is essential to determine the Hubble constant empirically with an accuracy of one per cent or better1. At present, the uncertainty on this constant is dominated by the uncertainty in the calibration of the Cepheid period-luminosity relationship2,3 (also known as the Leavitt law). ...


    pub_type: 杂志文章


    authors: Pietrzyński G,Graczyk D,Gallenne A,Gieren W,Thompson IB,Pilecki B,Karczmarek P,Górski M,Suchomska K,Taormina M,Zgirski B,Wielgórski P,Kołaczkowski Z,Konorski P,Villanova S,Nardetto N,Kervella P,Bresolin F,Kudritzki RP

    更新日期:2019-03-01 00:00:00