Abstract:
RATIONALE AND OBJECTIVES:This study compares the performance of T2 maps in the detection of prostate cancer (PCa) in comparison to T2-weighted (T2W) magnetic resonance images. MATERIALS AND METHODS:The prospective study was institutional review board approved. Consenting patients (n = 45) with histologic confirmed PCa underwent preoperative 3-T magnetic resonance imaging with or without endorectal coil. Two radiologists, working independently, marked regions of interests (ROIs) on PCa lesions separately on T2W images and T2 maps. Each ROI was assigned a score of 1-5 based on the confidence in accurately detecting cancer, with 5 being the highest confidence. Subsequently, the histologically confirmed PCa lesions (n = 112) on whole-mount sections were matched with ROIs to calculate sensitivity, positive predictive value (PPV), and radiologist confidence score. Quantitative T2 values of PCa and benign tissue ROIs were measured. RESULTS:Sensitivity and confidence score for PCa detection were similar for T2W images (51%, 4.5 ± 0.8) and T2 maps (52%, 4.5 ± 0.6). However, PPV was significantly higher (P = .001) for T2 maps (88%) compared to T2W (72%) images. The use of endorectal coils nominally improved sensitivity (T2W: 55 vs 47%, T2 map: 54% vs 48%) compared to the use of no endorectal coils, but not the PPV and the confidence score. Quantitative T2 values for PCa (105 ± 28 milliseconds) were significantly (P = 9.3 × 10-14) lower than benign peripheral zone tissue (211 ± 71 milliseconds), with moderate significant correlation with Gleason score (ρ = -0.284). CONCLUSIONS:Our study shows that review of T2 maps by radiologists has similar sensitivity but higher PPV compared to T2W images. Additional quantitative information obtained from T2 maps is helpful in differentiating cancer from normal prostate tissue and determining its aggressiveness.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Chatterjee A,Devaraj A,Mathew M,Szasz T,Antic T,Karczmar GS,Oto Adoi
10.1016/j.acra.2018.04.005subject
Has Abstractpub_date
2019-01-01 00:00:00pages
15-21issue
1eissn
1076-6332issn
1878-4046pii
S1076-6332(18)30188-0journal_volume
26pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:The authors developed a computerized method for delineating the costophrenic angles in digital posteroanterior chest radiographs to derive quantitative information that allows for detection of abnormal blunting of the costophrenic angle. MATERIALS AND METHODS:An automated lung-segmentation sch...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80151-7
更新日期:1998-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to present and evaluate a fully automated system for emphysema quantification on low-dose computed tomographic images. The platform standardizes emphysema measurements against changes in the reconstruction algorithm and slice thickness. MATERIALS AND METHODS:Emphysema...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.06.015
更新日期:2011-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to test the effectiveness of resident-prepared, independent learning cases in teaching residents chest radiology. MATERIALS AND METHODS:Three 2nd-year residents (one each from the University of Wisconsin, the Oregon Health Sciences University, and the University o...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s1076-6332(99)80059-2
更新日期:1999-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Epicardial adipose tissue (EAT), pericardial adipose tissue (PAT), and subcutaneous adipose tissue (SAT) are mediators of metabolic risk and may be involved in the pathogenesis of coronary artery disease. The aim of this study was to investigate the association of visceral and subcutaneous fat ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.08.017
更新日期:2010-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Balloon dilatation is a mechanical form of controlled injury used to alleviate vascular stenoses. Several factors influence successful angioplasty. Few mechanical models exist to illustrate the physical principles of balloon dilatation. METHODS:We used mechanical analysis of membrane stresses,...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80340-x
更新日期:1995-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study was performed to evaluate the feasibility of using a joystick-controlled robotic needle driver to place a 22-gauge needle for nerve and facet blocks. MATERIALS AND METHODS:Biplane fluoroscopy and a robotic needle driver were used to place 12 needles into the lumbar paraspinal region...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80356-2
更新日期:2002-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to determine the feasibility of using transabdominal ultrasonography (US) to monitor tumor growth and response to therapy in a mouse model of orthotopic bladder carcinoma. MATERIALS AND METHODS:Human bladder carcinoma cell suspensions were injected into the bladde...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(01)90038-8
更新日期:2001-02-01 00:00:00
abstract::We discuss the benefits of maintaining an active, rigorous, and highly structured grand rounds (GR) program in an academic radiology department. These benefits include education for faculty (continuing medical education), fellows, and residents and a venue for building collaboration and camaraderie within the departme...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.08.003
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:This study was to investigate the CT quantification of COVID-19 pneumonia and its impacts on the assessment of disease severity and the prediction of clinical outcomes in the management of COVID-19 patients. MATERIALS METHODS:Ninety-nine COVID-19 patients who were confirmed by positive nucleic acid test (NAT...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.09.004
更新日期:2020-12-01 00:00:00
abstract::This paper outlines the efforts of the American College of Radiology to understand the public perception of radiologists and to effect change in that perception. Through focus groups, in-depth interviews with Capitol Hill staff members, and national telephone surveys, it was found that the public is unaware of the edu...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.02.003
更新日期:2009-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Early loss of a sensory modality has been associated with cortical reorganization in both animal models and humans. The purpose of this study was to map visual activation with functional magnetic resonance (MR) imaging and to document possible developmental reorganization in the temporal lobe c...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80684-0
更新日期:2001-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study presents a method for generating breast masses and microcalcifications in mammography via simulation. This simulation method allows for the creation of large image datasets with particular lesions, which may serve as a useful tool for perception studies measuring imaging system perfo...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.03.015
更新日期:2006-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Pathogenic mutations in some genes elevate women's breast cancer risk, necessitating risk-reduction strategies. Unfortunately, women are underscreened for cancer risk, and when identified as potentially high risk, women seldom pursue genetic counseling or testing. To improve cancer risk managem...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.005
更新日期:2020-12-15 00:00:00
abstract:RATIONALE AND OBJECTIVES:We evaluated the effect of gravity on intrahepatic perfusion (IHP) in patients with a port-catheter system (PCS) implanted for hepatic arterial infusion chemotherapy (HAIC). Using fused single photon-emission computed tomographic (SPECT)/computed tomographic (CT) images, we compared IHP after t...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2008.12.004
更新日期:2009-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A survey was administered to fourth-year radiology residents after receiving their results from the first American Board of Radiology (ABR) Core examination in 2013. The purpose was to gather information regarding resources and study strategies to share with program directors and future residen...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.07.026
更新日期:2015-01-01 00:00:00
abstract::The outbreak of 2019 novel coronavirus (2019-nCoV) pneumonia was reported in Wuhan, Hubei Province, China in December 2019 and has spread internationally. This article discusses how radiology departments can most effectively respond to this public health emergency. ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.02.003
更新日期:2020-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to prospectively examine the impact of a tablet-based curriculum on the radiology resident educational experience. MATERIALS AND METHODS:A comprehensive tablet-based curriculum was developed by creating subspecialty modules with appropriate content level for each requ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.05.018
更新日期:2018-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To investigate the correlation between prevalence and degree of coronary artery calcification (CAC) and extracoronary calcifications (ECCs), scored quantitatively according to Agatston and semiquantitatively by visual analysis, in chest computed tomography (CT) studies obtained for lung cancer ...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2015.03.005
更新日期:2015-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Great expertise is necessary to mentally compile a series of individual two-dimensional image sections into a three-dimensional (3D) composite view that can aid in differential diagnosis. The purpose of this study was to test 3D volume-rendering techniques for differentiating congenital cystic ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80108-3
更新日期:2003-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Hyperpolarized (3)He magnetic resonance imaging (MRI) previously revealed the temporal and spatial heterogeneity of ventilation defects in asthmatics, but these findings have not been used in treatment studies or to guide personalized therapy. Our objective was to exploit the temporal and spati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.08.002
更新日期:2014-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Pulmonary vascular alteration is one of the characteristic features of chronic obstructive pulmonary disease (COPD). Recent studies suggest that vascular alteration is closely related to endothelial dysfunction and may be further influenced by emphysema. However, the relationship between morpho...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2009.07.022
更新日期:2010-01-01 00:00:00
abstract::Technologic advances have resulted in the expansion of web-based conferencing and education. While historically video-conferencing has been used for didactic educational sessions, we present its novel use in virtual radiology read-outs in the face of the COVID-19 pandemic. Knowledge of key aspects of set-up, implement...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.04.028
更新日期:2020-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We evaluated the inter- and intraobserver reproducibility of measuring five morphologic parameters of the anorectum in defecography (evacuation proctography). METHODS:Measurements from 42 defecographic studies were statistically analyzed. The parameters measured during resting, squeezing, and ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80719-6
更新日期:1994-11-01 00:00:00
abstract::Response Evaluation Criteria in Solid Tumors (RECIST) is a standardized methodology for determining therapeutic response to anticancer therapy using changes in lesion appearance on imaging studies. Many radiologists are now using RECIST in their routine clinical workflow, as part of consultative arrangements, or withi...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2015.01.015
更新日期:2015-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the feasibility and performance of an x-ray beam equalization system for chest radiography using anthropomorphic phantoms. MATERIALS AND METHODS:Area beam equalization involves the process of the initial unequalized image acquisition, attenuator thickness calculation, mask generati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00730-x
更新日期:2004-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Amphiphilic biocompatible polyoxyethylene (PEO)-based polymers form particles (micelles) that are 10-50 nm in diameter. In the current research, we successfully incorporated amphiphilic indium-111 (111In) and gadolinium chelates into these particles and used them as particulate contrast media i...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80448-x
更新日期:1996-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the image quality of virtual monochromatic images (VMI) reconstructed from dual-energy dual-source noncontrast head CT with different reconstruction kernels. MATERIALS AND METHODS:Twenty-five consecutive adult patients underwent noncontrast dual-energy CT. VMI were retrospectively ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.05.038
更新日期:2020-06-30 00:00:00
abstract:RATIONALE AND OBJECTIVES:(23)Na magnetic resonance imaging is a promising technique for the noninvasive imaging of renal function. Past investigations of the renal corticomedullary [(23)Na] gradient have relied on imaging only in the coronal plane and on cumbersome calculations of [(23)Na], which require the use of ext...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.10.009
更新日期:2013-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Prospective studies of radiologists' interpretations of selected radiographs reported 20-40 years ago indicated error rates of 30% and higher. The authors retrospectively evaluated the interpretations of groups of radiologists and determined a range of rates of disagreement in interpretation. Q...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80277-8
更新日期:1998-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Improvements in imaging technology have led to the increased use of computed tomography (CT). For example, micro-CT and quantitative CT (QCT) are now often used in osteoporosis research, in which micro-CT is able to analyze small bones or bone samples with high spatial resolution. In contrast, ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.09.017
更新日期:2009-04-01 00:00:00