Abstract:
:Background and purpose - Impaction bone grafting (IBG) is an established method in hip revision surgery to reconstruct loss of bone stock. There is limited knowledge concerning the actual bone remodelling process within the allograft. We investigated with repeated bone mineral density (BMD) measurements the biological process of bone remodelling in the allograft in vivo. We hypothesized that an initial decrease in BMD would be followed by an increase towards baseline values. Patients and methods - Dual-energy X-ray absorptiometry (DXA) was used to measure BMD values in 3 regions of interest (ROI) in 20 patients (average age at surgery 70 years, 11 males) after an acetabular reconstruction with IBG and a cemented cup. A postoperative DXA was used as baseline and DXA was repeated at 3 and 6 months and at 1 and 2 years. The Oxford Hip Score (OHS), the 12-Item Short Form Health Survey (SF12), and a 0 to 100 mm visual analogue scale (VAS) for pain and satisfaction were obtained simultaneously. Results - The overall mean BMD in the IBG regions increased significantly by 9% (95% CI 2-15) at 2 years' follow-up. In the cranial ROI BMD increased 14% (CI 6-22), whereas the BMD in the medial and caudal ROI showed an increase of 10% (CI 1-18) and 4% (CI -6-16), respectively. The OHS, SF12-mental, and VAS for pain all improved statistically significantly 2 years after surgery, with a mean VAS for satisfaction of 77 (CI 63-90) out of 100 points. The SF12-physical showed non-significant improvement. Interpretation - The BMD in the allograft gradually increased after IBG for acetabular reconstruction arthroplasties, particularly in the cranial ROI. An initial decrease in the BMD was not encountered. These BMD changes, as proxy measurements for bone remodeling, may indicate progressive apposition of vital new host bone in the grafted area.
journal_name
Acta Orthopjournal_title
Acta orthopaedicaauthors
Gerhardt DMJM,De Visser E,Hendrickx BW,Schreurs BW,Van Susante JLCdoi
10.1080/17453674.2018.1460776subject
Has Abstractpub_date
2018-06-01 00:00:00pages
302-307issue
3eissn
1745-3674issn
1745-3682journal_volume
89pub_type
杂志文章abstract::Background and purpose - Femoral neck preserving hip replacement has been suggested to improve clinical results and facilitate late revision. We compared the 2-year outcome and radiostereometric pattern of femoral head migration between the Collum Femoris Preserving (CFP) stem and the Corail stem. Patients and methods...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453674.2019.1577344
更新日期:2019-06-01 00:00:00
abstract::Background and purpose - About 86,000 total hip replacements (THR) have been registered in patients under 55 years in the National Joint Registry of England and Wales (NJR). The use of uncemented implants has increased, despite their outcomes not having been proven to be significantly better than cemented implants in ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2018.1427320
更新日期:2018-04-01 00:00:00
abstract::Background and purpose - During revision hip arthroplasty the dual mobility cup (DMC) is widely used to prevent dislocation despite limited knowledge of implant longevity. We determined the 5-year cup re-revision rates of DMC compared with unipolar cups (UC) following cup revisions in the Netherlands. Patients and met...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1617560
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:There is no consensus on the best surgical treatment of periprosthetic femoral fractures. We report our experience with a dynamic compression plate. PATIENTS AND METHODS:We reviewed the results of 18 periprosthetic femoral fractures treated with open reduction and internal fixation using the dynamic compres...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670510041529
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Since the osteogenic potential of bone marrow derived mesenchymal stem cells (BMSCs) becomes reduced with passage, establishment of culture condition that permit the rapid expansion of BMSCs while retaining their potential for differentiation is needed for clinical application. Bone morphogenetic proteins st...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670710013816
更新日期:2007-04-01 00:00:00
abstract::Background and purpose - Patient-specific instrumentation (PSI) for total knee arthroplasty (TKA) has been introduced to improve alignment and reduce outliers, increase efficiency, and reduce operation time. In order to improve our understanding of the outcomes of patient-specific instrumentation, we conducted a meta-...
journal_title:Acta orthopaedica
pub_type: 杂志文章,评审
doi:10.1080/17453674.2016.1193799
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The advent of highly crosslinked polyethylene has allowed the re-evaluation of the use of femoral heads larger than 32 mm for metal-on-polyethylene total hip arthroplasties. However, the effect of larger heads on the frictional torque of highly crosslinked polyethylene is unknown. METHODS:We performed an in...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610012881
更新日期:2006-10-01 00:00:00
abstract::Matrix metalloproteinases (MMPs) and related enzymes (ADAMs, ADAMTS) and their inhibitors control matrix turnover and function. Recent advances in our understanding of musculoskeletal conditions such as tendinopathy, arthritis, Dupuytren's disease, degenerative disc disease, and bone and soft tissue healing suggest th...
journal_title:Acta orthopaedica
pub_type: 杂志文章,评审
doi:10.3109/17453670903448257
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We have previously reported that the first 10 years of hip arthroplasty in Lithuania resulted in a higher cumulative revision rate than that observed in Sweden. We thus compared the corresponding results after introduaction of total knee replacement in Lithuania. METHODS:The 10-year revision rat...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670902804984
更新日期:2009-02-01 00:00:00
abstract::Background and purpose - Modular-neck hip stems have been identified with corrosion-related problems from the neck-stem junction. We report an ongoing varus deformity of modular-neck hip stems with simultaneous metal ion release observed during a study comparing the migration of modular vs. standard hip stems. Patient...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1853387
更新日期:2020-12-10 00:00:00
abstract:BACKGROUND AND PURPOSE:Metal artifact reduction sequence (MARS) MRI is widely advocated for surveillance of metal-on-metal hip arthroplasties (MOM-HAs). However, its use is limited by susceptibility artifact at the prosthesis-bone interface, local availability, patient compliance, and cost (Hayter et al. 2011a). We wan...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.964618
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Current techniques for epiphysiodesis involve opening of cortical windows; use of staples, screws, and tension devices; and fusion with curettes or drills. Complications may have serious consequences. There is a need for a more reliable, precise, and less traumatic procedure that overcomes the kn...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.939014
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND PURPOSES:The nervous system plays an important role in bone metabolism. However, the effect of denervation on bone formation during distraction osteogenesis (DO) remains unclear. We studied neural influence on bone regeneration during DO in a rabbit model. METHODS:24 New Zealand male white rabbits under...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.702389
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Periacetabular osteotomy improves radiographic predictors of osteoarthrosis and diminishes pain and functional impairment. No changes in function quantified by gait analysis have yet been documented. We evaluated the functional outcome of periacetabular osteotomy in relation to gait. METHODS:The gait patter...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610045920
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We previously evaluated a new uncemented femoral stem designed for elderly patients with a femoral neck fracture and found stable implant fixation and good clinical results up to 2 years postoperatively, despite substantial periprosthetic bone mineral loss. We now present the medium-term follow-u...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.931195
更新日期:2014-08-01 00:00:00
abstract::Background and purpose - Alternative bearing surfaces such as ceramics and highly crosslinked polyethylene (HXLPE) were developed in order to further improve implant performance of total hip arthroplasties (THAs). Whether these alternative bearing surfaces result in increased longevity is subject to debate. Patients a...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2017.1405669
更新日期:2018-04-01 00:00:00
abstract::Background and purpose - Osteoarthritis has become the most common indication for shoulder arthroplasty in Denmark, and the treatment strategies have changed towards the use of anatomical total shoulder arthroplasty and reverse shoulder arthroplasty. We investigated whether changes in the use of arthroplasty types hav...
journal_title:Acta orthopaedica
pub_type: 杂志文章,多中心研究
doi:10.1080/17453674.2019.1633759
更新日期:2019-10-01 00:00:00
abstract::Background and purpose - To date there is a lack of studies defining the anatomical position of the proximal fibula. This is especially relevant when planning surgical interventions affecting the knee joint such as permanent or temporary epiphysiodesis to correct leg length discrepancies or angular deformities in grow...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1769378
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Outcome measurement of shoulder arthroplasty is not standardized. We compared 3 scores and 1 evaluation form. PATIENTS AND METHODS:We report on 35 hemiarthroplasties of the shoulder (32 cementless). Mean age of the patients was 62 (29-87) years. After a mean follow-up of 6 years (range 2-18 years) patients ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610012980
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Integration of repaired cartilage with surrounding native cartilage is a major challenge for successful tissue-engineering strategies of cartilage repair. We investigated whether incorporation of mesenchymal stem cells (MSCs) into the collagen scaffold improves integration and repair of cartilage...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.958807
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The most common surgical approaches in total hip arthroplasty in Sweden are the posterior and the anterolateral transgluteal approach. Currently, however, there is insufficient evidence to prefer one over the other regarding risk of subsequent surgery. PATIENTS AND METHODS:We searched the Swedis...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.742394
更新日期:2012-12-01 00:00:00
abstract::Background and purpose - The long-term effects of computer-assisted surgery in total knee replacement (CAS) compared to conventionally operated knee replacement (CON) are still not clear. We compared survivorship and relative risk of revision in CAS and CON based on data from the Norwegian Arthroplasty Register. Patie...
journal_title:Acta orthopaedica
pub_type: 杂志文章,多中心研究
doi:10.1080/17453674.2016.1244884
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Overweight and a high level of physical activity are known risk factors for loosening of a total hip arthroplasty (THA) due to primary osteoarthritis. We wanted to investigate how these factors, together with age and sex, affect the risk of revision surgery. PATIENTS AND METHODS:We matched data from the Nor...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610013493
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The Knee Injury and Osteoarthritis Outcome Score (KOOS) is distinguished from other knee-specific measures by the inclusion of separate scales for evaluation of activities of daily living, sports and recreation function, and knee-related quality of life, with presentation of separate subscale sco...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.747921
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Complications related to the fibula during distraction osteogenesis could cause malalignment. Most published studies have analyzed only migration of the fibula during lengthening, with few studies examining the effects of fibular complications. PATIENTS AND METHODS:We retrospectively reviewed 12...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.665328
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The mechanism of failure of metal-on-metal (MoM) total hip arthroplasty (THA) has been related to a high rate of metal wear debris, which is partly generated from the head-trunnion interface. However, it is not known whether implant fixation is affected by metal wear debris. PATIENTS AND METHODS:49 cases of...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.922731
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:External fixators allowing movement during fracture healing are commonly used for treatment of unstable distal radius fractures. The dynamic Dynawrist fixator with the distal pins in metacarpal bone may avoid fixation problems in comminuted fractures and may reduce the risk of nerve injury. We co...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453670902807433
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:(18)F-FDG PET is a widely used tool for molecular imaging of oncological, cardiovascular, and neurological disorders. We evaluated (18)F-FDG microPET as an implant osteomyelitis imaging tool using a Staphylococcus aureus-induced peroperative implant infection in rabbits. METHODS:Intramedullary t...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.900894
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In recent years several different plate designs for internal fixation of fractures of the distal radius have been developed. However, few biomechanical studies have been performed to compare these new implants. The purpose of this study was to compare the mechanical properties of 5 different comm...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453670902947440
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:This randomized study compared clinical results after surgery for posttraumatic shoulder instability with either an anatomical repair or an older, less anatomical but commonly used method. The less anatomical procedure has been considered quicker and less demanding, but it has been questioned reg...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.3109/17453670902988345
更新日期:2009-06-01 00:00:00