Metalloproteinases and their inhibitors-diagnostic and therapeutic opportunities in orthopedics.

abstract：BACKGROUND AND PURPOSE:Most lung cancer patients with skeletal metastases have a short survival and it is difficult to identify those patients who will benefit from palliative surgery. We report complication and survival rates in a consecutive series of lung cancer patients who were operated for symptomatic skeletal me...

journal_title：Acta orthopaedica

authors： Weiss RJ,Wedin R

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:International standards indicate that bone allografts for human use should be stored in a -40 degrees C or colder environment and the storage time should be up to 5 years. Bone allografts contain lipids which oxidate and become toxic with time. MATERIAL AND METHODS:We determined lipid oxidation in femoral h...

journal_title：Acta orthopaedica

authors： Laitinen M,Kivikari R,Hirn M

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Operative findings during revision of metal-on-metal hip arthroplasty (MOMHA) vary widely and can involve massive soft tissue and bone disruption. As a result, planning of theater time and resources is difficult, surgery is challenging, and outcomes are often poor. We describe our experience with...

journal_title：Acta orthopaedica

authors： Liddle AD,Satchithananda K,Henckel J,Sabah SA,Vipulendran KV,Lewis A,Skinner JA,Mitchell AW,Hart AJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There are no reports in the literature on the influence of learning on the pedicle screw insertion. We studied the effect of learning on the rate of screw misplacement in patients with adolescent idiopathic scoliosis treated with segmental pedicle screw fixation. METHOD:We retrospectively evalua...

journal_title：Acta orthopaedica

authors： Abul-Kasim K,Ohlin A

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Resurfacing total hip arthroplasty (RTHA) may preserve the femoral neck bone stock postoperatively. Bone mineral density (BMD) may be affected by the hip position, which might bias longitudinal studies. We investigated the dependency of BMD precision on type of ROI and hip position. METHOD:We DX...

journal_title：Acta orthopaedica

authors： Penny JØ,Ovesen O,Brixen K,Varmarken JE,Overgaard S

更新日期：2010-06-01 00:00:00

abstract：:Background and purpose-Nonunion is common in femoral fractures. Previous studies suggested that the systemic immune response after trauma can interfere with fracture healing. Therefore, we investigated whether there is a relation between peripheral blood cell counts and healing of femur fractures. Patients and methods...

journal_title：Acta orthopaedica

authors： Hesselink L,Bastian OW,Heeres M,Ten Berg M,Huisman A,Hoefer IE,van Solinge WW,Koenderman L,van Wessem KJP,Leenen LPH,Hietbrink F

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Cyclooxigenase-2 (COX-2) inhibitors have been reported to delay fracture healing. To investigate the major inhibitory period of COX-2 inhibitors in fracture healing, we administrated etodolac, a COX-2-specific inhibitor, to a rat fracture model by altering the period of administration from early to late. ME...

journal_title：Acta orthopaedica

authors： Endo K,Sairyo K,Komatsubara S,Sasa T,Egawa H,Ogawa T,Yonekura D,Murakami R,Yasui N

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is continuing confusion among practitioners with regard to the optimal choice of anesthetic type for repair of hip fractures. We investigated whether type of anesthetic was associated with short-term mortality after hip fracture surgery. PATIENTS AND METHODS:We conducted a retrospective co...

journal_title：Acta orthopaedica

authors： Brox WT,Chan PH,Cafri G,Inacio MC

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSES:The nervous system plays an important role in bone metabolism. However, the effect of denervation on bone formation during distraction osteogenesis (DO) remains unclear. We studied neural influence on bone regeneration during DO in a rabbit model. METHODS:24 New Zealand male white rabbits under...

journal_title：Acta orthopaedica

authors： Song D,Jiang X,Zhu S,Li W,Khadka A,Hu J

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Total hip replacement is increasingly used in active, relatively healthy elderly patients with fractures of the femoral neck. Dislocation of the prosthesis is a severe complication, and there is still controversy regarding the optimal surgical approach and its influence on stability. We analyzed factors infl...

journal_title：Acta orthopaedica

authors： Enocson A,Hedbeck CJ,Tidermark J,Pettersson H,Ponzer S,Lapidus LJ

更新日期：2009-04-01 00:00:00

abstract：:Background and purpose - The Mitch proximal epiphyseal replacement (PER) was developed to preserve proximal femoral bone and minimize femoral neck fracture associated with hip resurfacing arthroplasty (HRA). We studied the survival and risk of revision of HRA compared with cementless metal-on-polyethylene (MoP) total ...

journal_title：Acta orthopaedica

authors： Tang-Jensen M,Kjærsgaard-Andersen P,Poulsen TK,Overgaard S,Varnum C

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:To overcome the mismatch between a stiff stem and the more elastic bone, the concept of isoelasticity was introduced in the 1970s. This concept was based on the assumption that the implant and the bone should deform as one unit to avoid stress shielding. The Robert Mathys (RM) cementless total hip replacemen...

journal_title：Acta orthopaedica

authors： Trebse R,Milosev I,Kovac S,Mikek M,Pisot V

更新日期：2005-04-01 00:00:00

abstract：:Background and purpose - Unnecessary radiographic and clinical follow-ups are common in treatment of pediatric fractures. We hypothesized that follow-up radiographs are unnecessary to monitor union of physeal fractures of the distal tibia.Patients and methods - All 224 (147 boys) children under 16 years old treated fo...

journal_title：Acta orthopaedica

authors： Stenroos A,Kosola J,Puhakka J,Laaksonen T,Ahonen M,Nietosvaara Y

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Fat embolism (FE), the release of bone marrow contents into the circulation and the subsequent cardiovascular changes, is still a potentially fatal com-plication during orthopedic surgery. Different causative factors have been suggested, but the exact pathomechanism of FE still remains unclear. We investigat...

journal_title：Acta orthopaedica

authors： Aebli N,Schwenke D,Davis G,Hii T,Theis JC,Krebs J

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Hospital-specific variation in outcome is generally considered to be an important source of information for clinical improvement. We have measured the magnitude of this variation. METHODS:We determined the revision risk in 37,642 cemented primary total knee arthroplasties inserted as a result of osteoarthri...

journal_title：Acta orthopaedica

authors： Robertsson O,Ranstam J,Lidgren L

更新日期：2006-06-01 00:00:00

abstract：:Background and purpose - Knee extensor (KE) muscle weakness is a modifiable feature commonly observed in individuals with knee osteoarthritis (KOA) and constitutes a potential target for patient-specific interventions. Therefore, in this study, we explored whether KE weakness is associated with radiographic (medial an...

journal_title：Acta orthopaedica

authors： Dell'isola A,Wirth W,Steultjens M,Eckstein F,Culvenor AG

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have previously shown that early fracture callus of rat rib has viscoelastic and contractile properties resembling those of smooth muscle. The cells responsible for this contractility have been hypothesized to be myofibroblast-like in nature. In soft-tissue healing, force generated by contract...

journal_title：Acta orthopaedica

authors： McDonald SJ,Dooley PC,McDonald AC,Schuijers JA,Ward AR,Grills BL

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Extracorporeal shock wave treatment has been used successfully for the treatment of avascular necrosis of the femoral head. The pathway of biological events by which this is accomplished has not been fully elucidated. BMP-2 is a key mediator of bone development and repair, and is uniquely require...

journal_title：Acta orthopaedica

authors： Ma HZ,Zeng BF,Li XL,Chai YM

更新日期：2008-02-01 00:00:00

abstract：:Background and purpose - A lifetime perspective on revision risks is needed for optimal timing of arthroplasty in osteoarthritis (OA) patients, weighing the benefit of total hip arthroplasty/total knee arthroplasty (THA/TKA) against the risk of revision, after which outcomes are less favorable. Therefore, we provide p...

journal_title：Acta orthopaedica

authors： Gademan MGJ,Van Steenbergen LN,Cannegieter SC,Nelissen RGHH,Marang-Van De Mheen PJ

更新日期：2021-01-22 00:00:00

abstract：:Background and purpose - Virtual reality simulation of hip fracture surgery is available for orthopedic residents nationwide in Denmark. Summative assessment of learning applying the learning curve cumulative summation test (LC-CUSUM) has not been utilized in orthopedic simulation training. The strength of the LC-CUSU...

journal_title：Acta orthopaedica

authors： Rölfing JD,Jensen RD,Paltved C

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:The use of impaction grafting in revisions with larger acetabular bone defects has mixed outcomes and sometimes high failures rates. PATIENTS AND METHODS:This prospective, single-center study involved a consecutive series of 24 patients who underwent complex reconstruction of the acetabulum using a trabecul...

journal_title：Acta orthopaedica

authors： Borland WS,Bhattacharya R,Holland JP,Brewster NT

更新日期：2012-08-01 00:00:00

abstract：UNLABELLED:BACKGROUND AND PURPOSE Analgesics can have undesirable effects. We assessed whether a single preoperative dose of 120 mg etoricoxib reduces the need for additional opioids after therapeutic arthroscopic knee surgery. METHODS A double-blind, placebo-controlled study was performed at a single center. 66 patien...

journal_title：Acta orthopaedica

authors： Lierz P,Losch H,Felleiter P

更新日期：2012-12-01 00:00:00

abstract：:Background and purpose - Femoral neck preserving hip replacement has been suggested to improve clinical results and facilitate late revision. We compared the 2-year outcome and radiostereometric pattern of femoral head migration between the Collum Femoris Preserving (CFP) stem and the Corail stem. Patients and methods...

journal_title：Acta orthopaedica

authors： Klein LJ,Puretic G,Mohaddes M,Kärrholm J

更新日期：2019-06-01 00:00:00

abstract：:Background and purpose - The uncemented Symax hip stem has shown early proximal ingrowth as result of the BONIT-hydroxyapatite (HA) coating and the distal DOTIZE surface treatment. We evaluated 2-year postoperative radiostereometric analysis (RSA) migration of the Symax hip stem in THA patients. We also investigated t...

journal_title：Acta orthopaedica

authors： Kruijntjens DSMG,Koster L,Kaptein BL,Jutten LMC,Arts JJ,Ten Broeke RHM

更新日期：2020-04-01 00:00:00

abstract：:Background and purpose - Patients having a total knee arthroplasty (TKA) after a previous high tibial osteotomy (HTO) constitute a minor group among those undergoing primary TKA for knee osteoarthritis (OA). There have been few reports on whether such patients differ pre- and postoperatively from those who undergo TKA...

journal_title：Acta orthopaedica

authors： W-Dahl A,Robertsson O

更新日期：2016-08-01 00:00:00

abstract：:Background and purpose - There is a general call for phased introduction of new implants, and one step in the introduction is an early evaluation of micromotion. We compared the micromotion in the Triathlon and its predecessor, the Duracon total knee prosthesis, concentrating especially on continuous migration over 5 ...

journal_title：Acta orthopaedica

authors： Molt M,Ryd L,Toksvig-Larsen S

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In recent years, intramedullary nails (INs) for the treatment of pertrochanteric hip fractures have gained prominence relative to conventional, sliding hip screws (SHSs). There is little empirical background for this development, however. A previous series of ours suggested that the use of SHS wa...

journal_title：Acta orthopaedica

authors： Palm H,Lysén C,Krasheninnikoff M,Holck K,Jacobsen S,Gebuhr P

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Optical coherence tomography (OCT) is a light-based imaging technique suitable for depiction of thin tissue layers such as articular cartilage. Quantification of results and direct comparison with a reference standard is needed to confirm the role of OCT in cartilage evaluation. MATERIALS AND ME...

journal_title：Acta orthopaedica

authors： Cernohorsky P,Kok AC,Bruin DM,Brandt MJ,Faber DJ,Tuijthof GJ,Kerkhoffs GM,Strackee SD,van Leeuwen TG

更新日期：2015-04-01 00:00:00

abstract：:Background and purpose - Impaction bone grafting (IBG) is an established method in hip revision surgery to reconstruct loss of bone stock. There is limited knowledge concerning the actual bone remodelling process within the allograft. We investigated with repeated bone mineral density (BMD) measurements the biological...

journal_title：Acta orthopaedica

authors： Gerhardt DMJM,De Visser E,Hendrickx BW,Schreurs BW,Van Susante JLC

更新日期：2018-06-01 00:00:00

abstract：:Background and purpose - Smoking is a modifiable risk factor that may adversely affect postoperative outcomes. Healthcare providers are increasingly denying smokers access to total hip and knee arthroplasty (THA and TKA) until they stop smoking. Evidence supporting this is unclear. We assessed the effect of smoking on...

journal_title：Acta orthopaedica

authors： Matharu GS,Mouchti S,Twigg S,Delmestri A,Murray DW,Judge A,Pandit HG

更新日期：2019-12-01 00:00:00