Cyclooxygenase-2 inhibitor delays fracture healing in rats.

abstract：BACKGROUND AND PURPOSE:The risk of complications in cirrhosis patients after orthopedic surgery is unclear. We examined this risk after total hip arthroplasty (THA) or total knee arthroplasty (TKA). PATIENTS AND METHODS:Using Danish healthcare registries, we identified all Danish residents who underwent a THA or TKA f...

journal_title：Acta orthopaedica

authors： Deleuran T,Vilstrup H,Overgaard S,Jepsen P

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Substantial bone loss in revision total knee arthroplasty (TKA) is a challenging problem. We studied whether impaction bone grafting provides long-term restoration of bone stock in the treatment of major bone defects in revision surgery of rotational and hinged knee arthroplasties (LINK Endo-Mode...

journal_title：Acta orthopaedica

authors： Hilgen V,Citak M,Vettorazzi E,Haasper C,Day K,Amling M,Gehrke T,Gebauer M

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The most common surgical approaches in total hip arthroplasty in Sweden are the posterior and the anterolateral transgluteal approach. Currently, however, there is insufficient evidence to prefer one over the other regarding risk of subsequent surgery. PATIENTS AND METHODS:We searched the Swedis...

journal_title：Acta orthopaedica

authors： Lindgren V,Garellick G,Kärrholm J,Wretenberg P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is increasing awareness that non-steroidal anti-inflammatory drugs (NSAIDs), and especially the cyclooxygenase-2 (COX-2) selective ones, may retard bone healing. We have used NSAIDs (indomethacin for at least 7 days) to prevent heterotopic ossification after acetabular reconstructions using...

journal_title：Acta orthopaedica

authors： van der Heide HJ,Hannink G,Buma P,Schreurs BW

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Length of stay (LOS) following total hip and knee arthroplasty (THA and TKA) has been reduced to about 3 days in fast-track setups with functional discharge criteria. Earlier studies have identified patient characteristics predicting LOS, but little is known about specific reasons for being hospi...

journal_title：Acta orthopaedica

authors： Husted H,Lunn TH,Troelsen A,Gaarn-Larsen L,Kristensen BB,Kehlet H

更新日期：2011-12-01 00:00:00

abstract：:Background and purpose - About one-fourth of hip fracture patients have cognitive impairment. We investigated whether patients' cognitive function affects surgical treatment, risk of reoperation, and mortality after hip fracture, based on data in the Norwegian Hip Fracture Register (NHFR).Patients and methods - This p...

journal_title：Acta orthopaedica

authors： Kristoffersen MH,Dybvik E,Steihaug OM,Kristensen TB,Engesaeter LB,Ranhoff AH,Gjertsen JE

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:In some countries, commercially available antibiotic powder-loaded acrylic bone cement is routinely used in joint replacement, while, in others, "off-label" formulations are used in selected procedures (where the antibiotic powder is blended manually with the powder of a plain cement in the operating room/th...

journal_title：Acta orthopaedica

authors： Lewis G,Janna S

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hip resurfacing arthroplasty is being used more and more frequently. The small ratio in size between the resurfaced femoral head and the relatively thick femoral neck raises the question of whether the range of motion is sufficient, particularly with regard to the high mobility required by younge...

journal_title：Acta orthopaedica

authors： Kluess D,Zietz C,Lindner T,Mittelmeier W,Schmitz KP,Bader R

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is considerable uncertainty about the optimal treatment of displaced 4-part fractures of the proximal humerus. Within the last decade, locking plate technology has been considered a breakthrough in the treatment of these complex injuries. METHODS:We systematically identified and reviewed c...

journal_title：Acta orthopaedica

authors： Brorson S,Frich LH,Winther A,Hróbjartsson A

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Commercial gentamicin-loaded bone cement beads (Septopal) constitute an effective delivery system for local antibiotic therapy. These beads are not available in all parts of the world, and are too expensive for frequent use in others. Thus, orthopedic surgeons worldwide make antibiotic-loaded bea...

journal_title：Acta orthopaedica

authors： Rasyid HN,van der Mei HC,Frijlink HW,Soegijoko S,van Horn JR,Busscher HJ,Neut D

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Surgical treatment of chronic acromioclavicular joint dislocations is challenging, and no single procedure can be considered to be the gold standard. In 2010, the GraftRope method (Arthrex Inc., Naples, FL) was introduced in a case series of 10 patients, showing good clinical results and no compl...

journal_title：Acta orthopaedica

authors： Nordin JS,Aagaard KE,Lunsjö K

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:We have previously reported that 6 months of oral treatment with clodronate reduced the migration of the NexGen total knee prosthesis during the first postoperative year, as measured by radiostereometry (RSA). We now report the 4-year results. METHODS:This was a double-blind randomized study, using RSA with...

journal_title：Acta orthopaedica

authors： Hilding M,Aspenberg P

更新日期：2006-12-01 00:00:00

abstract：:Background and purpose - Smoking is a modifiable risk factor that may adversely affect postoperative outcomes. Healthcare providers are increasingly denying smokers access to total hip and knee arthroplasty (THA and TKA) until they stop smoking. Evidence supporting this is unclear. We assessed the effect of smoking on...

journal_title：Acta orthopaedica

authors： Matharu GS,Mouchti S,Twigg S,Delmestri A,Murray DW,Judge A,Pandit HG

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The advent of highly crosslinked polyethylene has allowed the re-evaluation of the use of femoral heads larger than 32 mm for metal-on-polyethylene total hip arthroplasties. However, the effect of larger heads on the frictional torque of highly crosslinked polyethylene is unknown. METHODS:We performed an in...

journal_title：Acta orthopaedica

authors： Burroughs BR,Muratoglu OK,Bragdon CR,Wannomae KK,Christensen S,Lozynsky AJ,Harris WH

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Gamma irradiation has been widely used for sterilization of bone allografts. However, gamma irradiation alters proteins. This is favorable when it reduces immunogenicity, but is undesirable when osteoinductive proteins are damaged. Although the effect of gamma irradiation on BMPs has been studied, the effect...

journal_title：Acta orthopaedica

authors： Hannink G,Schreurs BW,Buma P

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Laboratory tests and early clinical studies have shown that highly cross-linked polyethylene (PE) markedly improves wear resistance compared to conventional PE. We evaluated this type of PE in two randomized clinical studies using radiostereometric analysis (RSA). The 2- and 3-year follow-up of these studies...

journal_title：Acta orthopaedica

authors： Digas G,Kärrholm J,Thanner J,Herberts P

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In recent years, intramedullary nails (INs) for the treatment of pertrochanteric hip fractures have gained prominence relative to conventional, sliding hip screws (SHSs). There is little empirical background for this development, however. A previous series of ours suggested that the use of SHS wa...

journal_title：Acta orthopaedica

authors： Palm H,Lysén C,Krasheninnikoff M,Holck K,Jacobsen S,Gebuhr P

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Overweight and a high level of physical activity are known risk factors for loosening of a total hip arthroplasty (THA) due to primary osteoarthritis. We wanted to investigate how these factors, together with age and sex, affect the risk of revision surgery. PATIENTS AND METHODS:We matched data from the Nor...

journal_title：Acta orthopaedica

authors： Flugsrud GB,Nordsletten L,Espehaug B,Havelin LI,Meyer HE

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathomechanics of the Essex-Lopresti lesion are not fully understood. We used human cadavers and documented the genesis of the injury with high-speed cameras. METHODS:4 formalin-fixed cadaveric specimens of human upper extremities were tested in a prototype, custom-made, drop-weight test ben...

journal_title：Acta orthopaedica

authors： Wegmann K,Engel K,Burkhart KJ,Ebinger M,Holz R,Brüggemann GP,Müller LP

更新日期：2014-04-01 00:00:00

abstract：:Background and purpose - Reverse shoulder arthroplasty (RSA) has become the treatment of choice for cuff-tear arthropathy. There are, however, concerns about the longevity and the outcome of an eventual revision procedure. Thus, resurfacing hemiarthroplasty (RHA) with extended articular surface has been suggested for ...

journal_title：Acta orthopaedica

authors： Ammitzboell M,Baram A,Brorson S,Olsen BS,Rasmussen JV

更新日期：2019-04-01 00:00:00

abstract：:Bone marrow transplantation can lead to osteogenic repair of intractable bone conditions. To achieve optimal clinical results, it is necessary to transplant as many cells with osteogenetic potential as possible. However, approaches involving special equipment and reagents for the extraction and purification of cells a...

journal_title：Acta orthopaedica

authors： Sakai S,Mishima H,Ishii T,Akaogi H,Yoshioka T,Uemura T,Ochiai N

更新日期：2008-06-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) and related enzymes (ADAMs, ADAMTS) and their inhibitors control matrix turnover and function. Recent advances in our understanding of musculoskeletal conditions such as tendinopathy, arthritis, Dupuytren's disease, degenerative disc disease, and bone and soft tissue healing suggest th...

journal_title：Acta orthopaedica

authors： Pasternak B,Aspenberg P

更新日期：2009-12-01 00:00:00

abstract：:Background and purpose-Nonunion is common in femoral fractures. Previous studies suggested that the systemic immune response after trauma can interfere with fracture healing. Therefore, we investigated whether there is a relation between peripheral blood cell counts and healing of femur fractures. Patients and methods...

journal_title：Acta orthopaedica

authors： Hesselink L,Bastian OW,Heeres M,Ten Berg M,Huisman A,Hoefer IE,van Solinge WW,Koenderman L,van Wessem KJP,Leenen LPH,Hietbrink F

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The osteogenic potency of erythropoietin (EPO) has been documented. However, its efficacy in a large-animal model has not yet been investigated; nor has a clinically safe dosage. The purpose of this study was to overcome such limitations of previous studies and thereby pave the way for possible c...

journal_title：Acta orthopaedica

authors： Rölfing JH,Jensen J,Jensen JN,Greve AS,Lysdahl H,Chen M,Rejnmark L,Bünger C

更新日期：2014-04-01 00:00:00

abstract：:Background and purpose - There is a lack of information on any associations between the functional outcome and age and diagnosis in patients who have undergone shoulder arthroplasty. We therefore evaluated the functional outcome in "young" and "old" patients treated with either hemiarthroplasty (HA) or total shoulder ...

journal_title：Acta orthopaedica

authors： Sowa B,Thierjung H,Bülhoff M,Loew M,Zeifang F,Bruckner T,Raiss P

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Tourniquet-related nerve injuries remain a concern in orthopedic surgery. The cuff pressures used today are generally lower, and therefore a decreasing incidence of peripheral nerve injuries might also be expected. However, there have been few neurophysiological studies describing the outcome aft...

journal_title：Acta orthopaedica

authors： Olivecrona C,Blomfeldt R,Ponzer S,Stanford BR,Nilsson BY

更新日期：2013-04-01 00:00:00

abstract：:Background and purpose - A lifetime perspective on revision risks is needed for optimal timing of arthroplasty in osteoarthritis (OA) patients, weighing the benefit of total hip arthroplasty/total knee arthroplasty (THA/TKA) against the risk of revision, after which outcomes are less favorable. Therefore, we provide p...

journal_title：Acta orthopaedica

authors： Gademan MGJ,Van Steenbergen LN,Cannegieter SC,Nelissen RGHH,Marang-Van De Mheen PJ

更新日期：2021-01-22 00:00:00

abstract：:Background and purpose - Patients having a total knee arthroplasty (TKA) after a previous high tibial osteotomy (HTO) constitute a minor group among those undergoing primary TKA for knee osteoarthritis (OA). There have been few reports on whether such patients differ pre- and postoperatively from those who undergo TKA...

journal_title：Acta orthopaedica

authors： W-Dahl A,Robertsson O

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Joint replacement with metal-on-metal (MOM) bearings have gained popularity in the last decades in young and active patients. However, the possible effects of MOM wear debris and its corrosion products are still the subject of debate. Alongside the potential disadvantages such as toxicity, the in...

journal_title：Acta orthopaedica

authors： Hosman AH,van der Mei HC,Bulstra SK,Busscher HJ,Neut D

更新日期：2010-10-01 00:00:00

abstract：:Background and purpose - Alternative bearing surfaces such as ceramics and highly crosslinked polyethylene (HXLPE) were developed in order to further improve implant performance of total hip arthroplasties (THAs). Whether these alternative bearing surfaces result in increased longevity is subject to debate. Patients a...

journal_title：Acta orthopaedica

authors： Peters RM,Van Steenbergen LN,Stevens M,Rijk PC,Bulstra SK,Zijlstra WP

更新日期：2018-04-01 00:00:00