Abstract:
BACKGROUND AND PURPOSE:The risk of complications in cirrhosis patients after orthopedic surgery is unclear. We examined this risk after total hip arthroplasty (THA) or total knee arthroplasty (TKA). PATIENTS AND METHODS:Using Danish healthcare registries, we identified all Danish residents who underwent a THA or TKA for primary osteoarthritis in the period 1995-2011. We compared the risk of complications in patients with or without cirrhosis. RESULTS:The surgical technique was similar in the 363 cirrhosis patients and in 109,159 reference patients, but cirrhosis patients were more likely to have been under general anesthesia (34% vs. 23%), were younger (median age 66 vs. 69 years), had a predominance of males (54% vs. 41%), had more comorbidity, and had had more hospitalizations preoperatively. Their risk of intraoperative complications was similar to that for reference patients (2.5% vs. 2.0%), but they had greater risk of dying during hospitalization or within 30 days of discharge (1.4% vs. 0.4%; aOR = 3.9, 95% CI: 1.5-10); greater risk of postoperative transfer to an intensive care unit (0.6% vs. 0.06%; aOR = 5.8, CI: 1.3-25) or a medical department (4.4% vs. 2.5%; aOR = 1.7, CI: 0.99-2.9); greater risk of readmission within 30 days of discharge (15% vs. 8%; aOR = 1.8, CI: 1.3-2.4); and greater risk of deep prosthetic infection (3.1% vs. 1.4%) or revision (3.7% vs. 1.7%) within 1 year. The chance of having an uncomplicated procedure was 81.0% (CI: 76.6-85.0) for cirrhosis patients and 90.0% (CI: 89.6-90.0) for reference patients. INTERPRETATION:Cirrhosis patients had a higher risk of postoperative complications after THA or TKA for primary osteoarthritis than patients without cirrhosis. This may have implications for orthopedic surgeons' postoperative management of cirrhosis patients, and preoperative assessment by a hepatologist may be indicated.
journal_name
Acta Orthopjournal_title
Acta orthopaedicaauthors
Deleuran T,Vilstrup H,Overgaard S,Jepsen Pdoi
10.3109/17453674.2014.961397subject
Has Abstractpub_date
2015-02-01 00:00:00pages
108-13issue
1eissn
1745-3674issn
1745-3682journal_volume
86pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:The pathomechanics of the Essex-Lopresti lesion are not fully understood. We used human cadavers and documented the genesis of the injury with high-speed cameras. METHODS:4 formalin-fixed cadaveric specimens of human upper extremities were tested in a prototype, custom-made, drop-weight test ben...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.887952
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Hospital volume has been suggested to be one of the best indicators of adverse orthopedic events in patients undergoing THR surgery. We therefore evaluated the effect of hospital volume on the length of stay, re-admissions, and complications of THR at the population level in Finland. METHODS:30,...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2010.533930
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Periacetabular osteotomy improves radiographic predictors of osteoarthrosis and diminishes pain and functional impairment. No changes in function quantified by gait analysis have yet been documented. We evaluated the functional outcome of periacetabular osteotomy in relation to gait. METHODS:The gait patter...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610045920
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:In Legg-Calvé-Perthes disease (LCPD), 4 major patterns (coxa plana, coxa magna, coxa vara, subluxation) of the femoral head are commonly observed. However, direct observation of pathological specimens is rarely possible. An animal model of LCPD may clarify the pathogenesis of femoral head deformity. ANIMALS...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610045678
更新日期:2006-02-01 00:00:00
abstract::Background and purpose - Recent studies have revealed deficiencies in the accuracy of data from joint registries when reoperations for prosthetic joint infections (PJIs) are reported, particularly when no components are changed. We compared the accuracy of data from the New Zealand Joint Registry (NZJR) to a multicent...
journal_title:Acta orthopaedica
pub_type: 杂志文章,多中心研究
doi:10.3109/17453674.2016.1171639
更新日期:2016-08-01 00:00:00
abstract::Background and purpose - Functional limitations after total knee arthroplasty (TKA) are common. In this longitudinal study, we wanted to identify subgroups of patients with distinct trajectories of pain-related interference with walking during the first year after TKA and to determine which demographic, clinical, symp...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2016.1237440
更新日期:2016-12-01 00:00:00
abstract::Background and purpose - Most guidelines use patient age as a primary decision factor when choosing between osteosynthesis or arthroplasty in displaced femoral neck fractures. We evaluate reoperation and death risk within 1 year after osteosynthesis, and estimate the influence of age, sex, degree of displacement, and ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1698503
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:We developed a total hip system using osseointegration guidelines, a metaphyseal-loading proximal femoral replacement in the retained neck and a dual-geometry titanium shell in the acetabulum. PATIENTS AND METHODS:A randomized controlled clinical trial was undertaken in 52 patients (53 hips), using the ceme...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453670610012601
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ultrasound is used for imaging of pseudotumors associated with metal-on-metal (MoM) hips. Ultrasound has been compared with magnetic resonance imaging, but to date there have been no studies comparing ultrasound findings and revision findings. METHODS:We evaluated the sensitivity and specificity...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.1001970
更新日期:2015-06-01 00:00:00
abstract::Background and purpose - Femoral neck preserving hip replacement has been suggested to improve clinical results and facilitate late revision. We compared the 2-year outcome and radiostereometric pattern of femoral head migration between the Collum Femoris Preserving (CFP) stem and the Corail stem. Patients and methods...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453674.2019.1577344
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The PRECICE intramedullary limb lengthening system uses a new technique with a magnetic rod and a motorized external remote controller (ERC) with rotational magnetic field. We evaluated the reliability and safety of the PRECICE system. METHODS:We compared our preliminary results with PRECICE in ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.913955
更新日期:2014-06-01 00:00:00
abstract::Background and purpose - A risk-stratification algorithm for metal-on-metal hip arthroplasty (MoMHA) patients was devised by US experts to help clinicians make management decisions. However, the proposed algorithm did not cover all potential patient or surgical abnormalities. Therefore we adapted the US risk-stratific...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1659661
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although total ankle replacement (TAR) is a recognized procedure for treatment of the painful arthritic ankle, the best choice of implant and the long-term results are still unknown. We evaluated the survival of two TAR designs and factors associated with survival using data from the nationwide a...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453671003685459
更新日期:2010-02-01 00:00:00
abstract::Perspective Orthopaedic training in the United Kingdom has changed little from the Halstedian apprenticeship model of graduated responsibility, with the mantra "see one, do one, teach one". Whilst still relevant in surgical teaching, the current and ongoing disruption to surgical training secondary to the coronavirus ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1845437
更新日期:2020-11-11 00:00:00
abstract::Background and purpose - Socioeconomic status is associated with the outcome of major surgery. We investigated the association of socioeconomic status with the risk of early mortality and readmissions after primary total hip arthroplasty (THA). Patients and methods - We obtained information on income, education, immig...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1598710
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:The aims of this study were to quantify the risk and identify the causes of early postoperative mortality after total hip arthroplasty. This would help clinicians address preventable causes of death and help in accurate counseling and consenting of patients. METHODS:We determined the death rate at 90 days i...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610046244
更新日期:2006-06-01 00:00:00
abstract::Background and purpose - Mobile-bearing total knee prostheses (TKPs) were developed in the 1970s in an attempt to increase function and improve implant longevity. However, modern fixed-bearing designs like the single-radius TKP may provide similar advantages. We compared tibial component migration measured with radios...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453674.2018.1429108
更新日期:2018-04-01 00:00:00
abstract:UNLABELLED:BACKGROUND AND PURPOSE Analgesics can have undesirable effects. We assessed whether a single preoperative dose of 120 mg etoricoxib reduces the need for additional opioids after therapeutic arthroscopic knee surgery. METHODS A double-blind, placebo-controlled study was performed at a single center. 66 patien...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.3109/17453674.2012.747053
更新日期:2012-12-01 00:00:00
abstract::Background and purpose - Uncemented stems are increasingly used in revision hip arthroplasty, but only a few studies have analyzed the outcomes of uncemented and cemented revision stems in large cohorts of patients. We compared the results of uncemented and cemented revision stems. Patients and methods - 1,668 uncemen...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1624336
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The frontal pelvic plane has traditionally served as the reference plane for implantation of the acetabular cup during total hip arthroplasty, with referencing performed with the patient supine on the operating table. During daily activities in an upright position, the frontal pelvic plane changes from a hor...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670510045471
更新日期:2005-12-01 00:00:00
abstract::Background and purpose - Survivorship of total hip arthroplasty (THA) with the ultra-high molecular weight polyethylene (UHMWPE) monoblock cup has been limited due to periprosthetic osteolysis and aseptic loosening, secondary to wear of the UHMWPE. In response, a vitamin E blended highly cross-linked polyethylene (HXL...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1807220
更新日期:2020-12-01 00:00:00
abstract::Background and purpose - There is a lack of information on any associations between the functional outcome and age and diagnosis in patients who have undergone shoulder arthroplasty. We therefore evaluated the functional outcome in "young" and "old" patients treated with either hemiarthroplasty (HA) or total shoulder ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2017.1280656
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Gamma irradiation has been widely used for sterilization of bone allografts. However, gamma irradiation alters proteins. This is favorable when it reduces immunogenicity, but is undesirable when osteoinductive proteins are damaged. Although the effect of gamma irradiation on BMPs has been studied, the effect...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610013394
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There are limited population-based data on utilization, outcomes, and trends in total knee arthroplasty (TKA). The purpose of this study was to examine TKA utilization and short-term outcomes in a pre-paid health maintenance organization (HMO), and to determine whether rates and revision burden c...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670810016902
更新日期:2008-12-01 00:00:00
abstract::Background and purpose - Radiostereometric analysis (RSA) is the gold standard to study micromotion of joint replacements. RSA requires the acquisition of additional radiographs increasing the radiation dose of patients included in RSA studies. It is important to keep this dose as low as possible. Effective radiation ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1767443
更新日期:2020-08-01 00:00:00
abstract::- Meniscal root tears (MRTs) are defined as radial tears within 1 cm of the meniscal root insertion, or an avulsion of the insertion of the meniscus. These injuries change joint loading due to failure of the meniscus to convert axial loads into hoop stresses, resulting in joint overloading and degenerative changes in ...
journal_title:Acta orthopaedica
pub_type: 杂志文章,评审
doi:10.1080/17453674.2016.1202945
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:The in vivo pharmacokinetics of gentamycin- loaded collagen fleeces in humans have not been described in the current literature. We therefore analyzed in vivo pharmacokinetics of these fleeces when used in the treatment of periprosthetic infections. PATIENTS AND METHODS:Gentamycin concentrations were measur...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670810016650
更新日期:2008-10-01 00:00:00
abstract::Background and purpose - Virtual reality simulation of hip fracture surgery is available for orthopedic residents nationwide in Denmark. Summative assessment of learning applying the learning curve cumulative summation test (LC-CUSUM) has not been utilized in orthopedic simulation training. The strength of the LC-CUSU...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1777511
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Laboratory tests and early clinical studies have shown that highly cross-linked polyethylene (PE) markedly improves wear resistance compared to conventional PE. We evaluated this type of PE in two randomized clinical studies using radiostereometric analysis (RSA). The 2- and 3-year follow-up of these studies...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453670710014518
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Hip resurfacing arthroplasty is being used more and more frequently. The small ratio in size between the resurfaced femoral head and the relatively thick femoral neck raises the question of whether the range of motion is sufficient, particularly with regard to the high mobility required by younge...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670810016803
更新日期:2008-12-01 00:00:00