Irradiation has no effect on the incorporation of impacted morselized bone: a bone chamber study in goats.

Abstract:

BACKGROUND:Gamma irradiation has been widely used for sterilization of bone allografts. However, gamma irradiation alters proteins. This is favorable when it reduces immunogenicity, but is undesirable when osteoinductive proteins are damaged. Although the effect of gamma irradiation on BMPs has been studied, the effect of irradiation on the process of incorporation of morselized bone chips remains unclear. We studied the effects of sterilization by gamma irradiation on the incorporation of impacted morselized allografts. METHODS:Bone chambers with impacted allografts, rinsed impacted allografts, allografts that were rinsed and subsequently irradiated, and an empty control were implanted in proximal medial tibiae of goats. Incorporation was evaluated using histology and histomorphometry. RESULTS:Histology revealed evidence of bone graft incorporation, which proceeded in a similar way in unprocessed, rinsed, and both rinsed and irradiated bone grafts. After 12 weeks, no difference in bone and tissue ingrowth was found between the unprocessed, the rinsed, and the rinsed and subsequently irradiated allografts. The amount of unresorbed graft remnant was highest in the unprocessed bone grafts. INTERPRETATION:We conclude that sterilization with gamma irradiation does not influence the incorporation of impacted rinsed bone allografts.

journal_name

Acta Orthop

journal_title

Acta orthopaedica

authors

Hannink G,Schreurs BW,Buma P

doi

10.1080/17453670610013394

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

31-8

issue

1

eissn

1745-3674

issn

1745-3682

pii

776344006

journal_volume

78

pub_type

杂志文章
  • Risk of reoperation within 12 months following osteosynthesis of a displaced femoral neck fracture is linked mainly to initial fracture displacement while risk of death may be linked to bone quality: a cohort study from Danish Fracture Database.

    abstract::Background and purpose - Most guidelines use patient age as a primary decision factor when choosing between osteosynthesis or arthroplasty in displaced femoral neck fractures. We evaluate reoperation and death risk within 1 year after osteosynthesis, and estimate the influence of age, sex, degree of displacement, and ...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2019.1698503

    authors: Nyholm AM,Palm H,Sandholdt H,Troelsen A,Gromov K,DFDB COLLABORATORS.

    更新日期:2020-02-01 00:00:00

  • Intramedullary nailing appears to be superior in pertrochanteric hip fractures with a detached greater trochanter: 311 consecutive patients followed for 1 year.

    abstract:BACKGROUND AND PURPOSE:In recent years, intramedullary nails (INs) for the treatment of pertrochanteric hip fractures have gained prominence relative to conventional, sliding hip screws (SHSs). There is little empirical background for this development, however. A previous series of ours suggested that the use of SHS wa...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2011.566143

    authors: Palm H,Lysén C,Krasheninnikoff M,Holck K,Jacobsen S,Gebuhr P

    更新日期:2011-04-01 00:00:00

  • An infrapatellar nerve block reduces knee pain in patients with chronic anterior knee pain after tibial nailing: a randomized, placebo-controlled trial in 34 patients.

    abstract::Background and purpose - Anterior knee pain is common after tibial nailing. Its origin is poorly understood. Injury of the infrapatellar nerve is a possible cause. In this randomized controlled trial we compared changes in knee pain after an infrapatellar nerve block with lidocaine or placebo in patients with persiste...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/17453674.2019.1613808

    authors: Leliveld MS,Kamphuis SJM,Verhofstad MHJ

    更新日期:2019-08-01 00:00:00

  • Migration and clinical outcome of mobile-bearing versus fixed-bearing single-radius total knee arthroplasty.

    abstract::Background and purpose - Mobile-bearing total knee prostheses (TKPs) were developed in the 1970s in an attempt to increase function and improve implant longevity. However, modern fixed-bearing designs like the single-radius TKP may provide similar advantages. We compared tibial component migration measured with radios...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/17453674.2018.1429108

    authors: Van Hamersveld KT,Marang-Van De Mheen PJ,Van Der Heide HJL,Van Der Linden-Van Der Zwaag HMJ,Valstar ER,Nelissen RGHH

    更新日期:2018-04-01 00:00:00

  • No radiological and clinical advantages with patient-specific positioning guides in total knee replacement.

    abstract::Background and purpose - Although the use of patient-specific positioning guides (PSPGs) in total knee replacement (TKR) in theory is promising, the technique has not yet proven its superior- ity compared with the conventional method. We compared radio- logical alignment and clinical outcome between TKR performed with...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1080/17453674.2017.1393732

    authors: Van Leeuwen JAMJ,Snorrason F,Röhrl SM

    更新日期:2018-02-01 00:00:00

  • A randomized RSA study concentrating especially on continuous migration.

    abstract::Background and purpose - There is a general call for phased introduction of new implants, and one step in the introduction is an early evaluation of micromotion. We compared the micromotion in the Triathlon and its predecessor, the Duracon total knee prosthesis, concentrating especially on continuous migration over 5 ...

    journal_title:Acta orthopaedica

    pub_type: 评论,杂志文章

    doi:10.3109/17453674.2016.1166876

    authors: Molt M,Ryd L,Toksvig-Larsen S

    更新日期:2016-06-01 00:00:00

  • The effect of hospital volume on length of stay, re-admissions, and complications of total hip arthroplasty.

    abstract:BACKGROUND AND PURPOSE:Hospital volume has been suggested to be one of the best indicators of adverse orthopedic events in patients undergoing THR surgery. We therefore evaluated the effect of hospital volume on the length of stay, re-admissions, and complications of THR at the population level in Finland. METHODS:30,...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2010.533930

    authors: Mäkelä KT,Häkkinen U,Peltola M,Linna M,Kröger H,Remes V

    更新日期:2011-02-01 00:00:00

  • Increased mortality after anterior shoulder dislocation: 255 patients aged 12-40 years followed for 25 years.

    abstract:BACKGROUND:No data exist regarding mortality rate in young patients with a first-time anterior shoulder dislocation. A cohort of 255 patients aged 12-40 years had a primary anterior shoulder dislocation during the years 1978 and 1979. After 10 years, 9 of the patients had died--which is a high figure for this cohort of...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453670710014617

    authors: Hovelius L,Nilsson JA,Nordqvist A

    更新日期:2007-12-01 00:00:00

  • Outcome and reproducibility of data concerning the Oxford unicompartmental knee arthroplasty: a structured literature review including arthroplasty registry data.

    abstract:BACKGROUND AND PURPOSE:The reproducibility of results and potential confounders in sample-based studies is important to consider in the assessment of studies. Comprehensive arthroplasty registers could serve as a reference dataset for comparative analyses. We analyzed an implant that is frequently used worldwide, the O...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,评审

    doi:10.3109/17453674.2011.566134

    authors: Labek G,Sekyra K,Pawelka W,Janda W,Stöckl B

    更新日期:2011-04-01 00:00:00

  • Coronal alignment of the lower limb.

    abstract:BACKGROUND:The coronal alignment of the lower limb is important for knee reconstruction procedures. However, normal alignment is hard to define because of its wide variation among normal individuals. Our hypothesis was that the variation in the normal anatomy as assessed by radiography is greater than commonly accepted...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:

    authors: Jenny JY,Boeri C,Ballonzoli L

    更新日期:2005-06-01 00:00:00

  • Posterior meniscal root injuries.

    abstract::- Meniscal root tears (MRTs) are defined as radial tears within 1 cm of the meniscal root insertion, or an avulsion of the insertion of the meniscus. These injuries change joint loading due to failure of the meniscus to convert axial loads into hoop stresses, resulting in joint overloading and degenerative changes in ...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,评审

    doi:10.1080/17453674.2016.1202945

    authors: Moatshe G,Chahla J,Slette E,Engebretsen L,Laprade RF

    更新日期:2016-10-01 00:00:00

  • Locking plate osteosynthesis in displaced 4-part fractures of the proximal humerus.

    abstract:BACKGROUND AND PURPOSE:There is considerable uncertainty about the optimal treatment of displaced 4-part fractures of the proximal humerus. Within the last decade, locking plate technology has been considered a breakthrough in the treatment of these complex injuries. METHODS:We systematically identified and reviewed c...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,评审

    doi:10.3109/17453674.2011.588856

    authors: Brorson S,Frich LH,Winther A,Hróbjartsson A

    更新日期:2011-08-01 00:00:00

  • The fascial band from semitendinosus to gastrocnemius: the critical point of hamstring harvesting: an anatomical study of 23 cadavers.

    abstract:BACKGROUND:Arthroscopically-assisted reconstruction of the anterior cruciate ligament with hamstring tendons has achieved widespread acceptance; however, the anatomy of these tendons may cause technical problems at harvesting. METHODS:We studied the anatomy of the fascial band between semitendinosus and gastrocnemius ...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453670710013933

    authors: Tuncay I,Kucuker H,Uzun I,Karalezli N

    更新日期:2007-06-01 00:00:00

  • Surgery for skeletal metastases in lung cancer.

    abstract:BACKGROUND AND PURPOSE:Most lung cancer patients with skeletal metastases have a short survival and it is difficult to identify those patients who will benefit from palliative surgery. We report complication and survival rates in a consecutive series of lung cancer patients who were operated for symptomatic skeletal me...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2011.552779

    authors: Weiss RJ,Wedin R

    更新日期:2011-02-01 00:00:00

  • Comparison of optical coherence tomography and histopathology in quantitative assessment of goat talus articular cartilage.

    abstract:BACKGROUND AND PURPOSE:Optical coherence tomography (OCT) is a light-based imaging technique suitable for depiction of thin tissue layers such as articular cartilage. Quantification of results and direct comparison with a reference standard is needed to confirm the role of OCT in cartilage evaluation. MATERIALS AND ME...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2014.979312

    authors: Cernohorsky P,Kok AC,Bruin DM,Brandt MJ,Faber DJ,Tuijthof GJ,Kerkhoffs GM,Strackee SD,van Leeuwen TG

    更新日期:2015-04-01 00:00:00

  • How do EQ-5D-3L and EQ-5D-5L compare in a Swedish total hip replacement population?

    abstract::Background and purpose - To better detect small changes in postoperative outcome following total hip replacement (THR), the Swedish Hip Arthroplasty Register (SHAR) has decided to change from the EQ-5D-3L (3L) to the EQ-5D-5L (5L). To enable comparison of results obtained with use of the 2 versions of EQ-5D, transfera...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2020.1746124

    authors: Eneqvist T,Nemes S,Kärrholm J,Burström K,Rolfson O

    更新日期:2020-06-01 00:00:00

  • Gait improvement surgery in ambulatory children with diplegic cerebral palsy.

    abstract:BACKGROUND AND PURPOSE:Instrumented 3-D gait analyses (GA) in children with cerebral palsy (CP) have shown improved gait function 1 year postoperatively. Using GA, we assessed the outcome after 5 years and evaluated parental satisfaction with the surgery and the need for additional surgery. PATIENTS AND METHODS:34 amb...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2015.1011927

    authors: Terjesen T,Lofterød B,Skaaret I

    更新日期:2015-01-01 00:00:00

  • Introduction of total knee arthroplasty in Lithuania: Results from the first 10 years.

    abstract:BACKGROUND AND PURPOSE:We have previously reported that the first 10 years of hip arthroplasty in Lithuania resulted in a higher cumulative revision rate than that observed in Sweden. We thus compared the corresponding results after introduaction of total knee replacement in Lithuania. METHODS:The 10-year revision rat...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453670902804984

    authors: Tarasevicius S,Stucinskas J,Robertsson O,Wingstrand H

    更新日期:2009-02-01 00:00:00

  • Fibula-related complications during bilateral tibial lengthening: 60 patients followed for mean 5 years.

    abstract:BACKGROUND AND PURPOSE:Complications related to the fibula during distraction osteogenesis could cause malalignment. Most published studies have analyzed only migration of the fibula during lengthening, with few studies examining the effects of fibular complications. PATIENTS AND METHODS:We retrospectively reviewed 12...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2012.665328

    authors: Kim SJ,Agashe MV,Song SH,Song HR

    更新日期:2012-06-01 00:00:00

  • Cognitive impairment influences the risk of reoperation after hip fracture surgery: results of 87,573 operations reported to the Norwegian Hip Fracture Register.

    abstract::Background and purpose - About one-fourth of hip fracture patients have cognitive impairment. We investigated whether patients' cognitive function affects surgical treatment, risk of reoperation, and mortality after hip fracture, based on data in the Norwegian Hip Fracture Register (NHFR).Patients and methods - This p...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2019.1709712

    authors: Kristoffersen MH,Dybvik E,Steihaug OM,Kristensen TB,Engesaeter LB,Ranhoff AH,Gjertsen JE

    更新日期:2020-04-01 00:00:00

  • Poor patient-reported outcome after shoulder replacement in young patients with cuff-tear arthropathy: a matched-pair analysis from the Danish Shoulder Arthroplasty Registry.

    abstract::Background and purpose - Reverse shoulder arthroplasty (RSA) has become the treatment of choice for cuff-tear arthropathy. There are, however, concerns about the longevity and the outcome of an eventual revision procedure. Thus, resurfacing hemiarthroplasty (RHA) with extended articular surface has been suggested for ...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2018.1563855

    authors: Ammitzboell M,Baram A,Brorson S,Olsen BS,Rasmussen JV

    更新日期:2019-04-01 00:00:00

  • Survival of uncemented acetabular monoblock cups: evaluation of 210 hips in the Swedish Hip Arthroplasty Register.

    abstract:BACKGROUND AND PURPOSE:Monoblock acetabular cups represent a subtype of uncemented cups with the polyethylene liner molded into a metal shell, thus eliminating-or at least minimizing-potential backside wear. We hypothesized that the use of monoblock cups could reduce the incidence of osteolysis and aseptic loosening, a...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2012.688726

    authors: Weiss RJ,Hailer NP,Stark A,Kärrholm J

    更新日期:2012-06-01 00:00:00

  • Predicting individual knee range of motion, knee pain, and walking limitation outcomes following total knee arthroplasty.

    abstract::Background and purpose - Up to 20% of patients are dissatisfied after total knee arthroplasty (TKA), mainly because of pain and restricted physical function. We developed a prediction model for 6-month knee range of motion, knee pain, and walking limitations in patients undergoing TKA surgery. Patients and methods - W...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2018.1560647

    authors: Pua YH,Poon CL,Seah FJ,Thumboo J,Clark RA,Tan MH,Chong HC,Tan JW,Chew ES,Yeo SJ

    更新日期:2019-04-01 00:00:00

  • Similar clinical outcome after unicompartmental knee arthroplasty using a conventional or accelerated care program: a randomized, controlled study of 40 patients.

    abstract:UNLABELLED:BACKGROUND AND PURPOSE Over the last 5 years, there has been increasing interest in reducing length of hospitalization (LOS) through accelerated programs. We examined the clinical outcome of patients undergoing a unicompartmental knee replacement (UKR) in an accelerated care program (A group) compared to a c...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/17453670903035559

    authors: Borgwardt L,Zerahn B,Bliddal H,Christiansen C,Sylvest J,Borgwardt A

    更新日期:2009-06-01 00:00:00

  • Increased use of total shoulder arthroplasty for osteoarthritis and improved patient-reported outcome in Denmark, 2006-2015: a nationwide cohort study from the Danish Shoulder Arthroplasty Registry.

    abstract::Background and purpose - Osteoarthritis has become the most common indication for shoulder arthroplasty in Denmark, and the treatment strategies have changed towards the use of anatomical total shoulder arthroplasty and reverse shoulder arthroplasty. We investigated whether changes in the use of arthroplasty types hav...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章,多中心研究

    doi:10.1080/17453674.2019.1633759

    authors: Rasmussen JV,Amundsen A,Sørensen AKB,Klausen TW,Jakobsen J,Jensen SL,Olsen BS

    更新日期:2019-10-01 00:00:00

  • Reducing orthopaedic theatre exposure during the COVID-19 lockdown: does a shift towards virtual reality-based training offer a solution?

    abstract::Perspective Orthopaedic training in the United Kingdom has changed little from the Halstedian apprenticeship model of graduated responsibility, with the mantra "see one, do one, teach one". Whilst still relevant in surgical teaching, the current and ongoing disruption to surgical training secondary to the coronavirus ...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2020.1845437

    authors: Arshad A,Zaveri A,Atkinson H

    更新日期:2020-11-11 00:00:00

  • A vitamin E blended highly cross-linked polyethylene acetabular cup results in less wear: 6-year results of a randomized controlled trial in 199 patients.

    abstract::Background and purpose - Survivorship of total hip arthroplasty (THA) with the ultra-high molecular weight polyethylene (UHMWPE) monoblock cup has been limited due to periprosthetic osteolysis and aseptic loosening, secondary to wear of the UHMWPE. In response, a vitamin E blended highly cross-linked polyethylene (HXL...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.1080/17453674.2020.1807220

    authors: Massier JRA,Van Erp JHJ,Snijders TE,Gast A

    更新日期:2020-12-01 00:00:00

  • Similar mortality with general or regional anesthesia in elderly hip fracture patients.

    abstract:BACKGROUND AND PURPOSE:There is continuing confusion among practitioners with regard to the optimal choice of anesthetic type for repair of hip fractures. We investigated whether type of anesthetic was associated with short-term mortality after hip fracture surgery. PATIENTS AND METHODS:We conducted a retrospective co...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2015.1128781

    authors: Brox WT,Chan PH,Cafri G,Inacio MC

    更新日期:2016-01-01 00:00:00

  • Dislocation of total hip replacement in patients with fractures of the femoral neck.

    abstract:BACKGROUND:Total hip replacement is increasingly used in active, relatively healthy elderly patients with fractures of the femoral neck. Dislocation of the prosthesis is a severe complication, and there is still controversy regarding the optimal surgical approach and its influence on stability. We analyzed factors infl...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453670902930024

    authors: Enocson A,Hedbeck CJ,Tidermark J,Pettersson H,Ponzer S,Lapidus LJ

    更新日期:2009-04-01 00:00:00

  • Low bone mineral density is not related to failure in femoral neck fracture patients treated with internal fixation.

    abstract:BACKGROUND AND PURPOSE:Internal fixation (IF) in femoral neck fractures has high reoperation rates and some predictors of failure are known, such as age, quality of reduction, and implant positioning. Finding new predictors of failure is an ongoing process, and in this study we evaluated the importance of low bone mine...

    journal_title:Acta orthopaedica

    pub_type: 杂志文章

    doi:10.3109/17453674.2013.875360

    authors: Viberg B,Ryg J,Overgaard S,Lauritsen J,Ovesen O

    更新日期:2014-02-01 00:00:00