Abstract:
BACKGROUND:In Legg-Calvé-Perthes disease (LCPD), 4 major patterns (coxa plana, coxa magna, coxa vara, subluxation) of the femoral head are commonly observed. However, direct observation of pathological specimens is rarely possible. An animal model of LCPD may clarify the pathogenesis of femoral head deformity. ANIMALS AND METHODS:In 26 piglets, we interrupted the vascular supply to the capital femoral epiphysis by cutting the ligamentum teres and ligating the femoral neck containing the epiphyseal artery. 6-7 piglets in each experimental group were killed at early (2 and 4 weeks: P2 and P4), intermediate (12 weeks: P12), and late (20 weeks: P20) periods. We examined the extracted femoral heads macroscopically and radiographically. RESULTS:The mean decrease in epiphyseal height was 1.5 mm, 4.1 mm, 5.0 mm, and 7.5 mm in P2, P4, P12 and P20, respectively (rs = 0.76, p = 0.002). The mean increase of diameter was 4.1 mm, 6.9 mm, and 6.8 mm in P4, P12 and P20, respectively. Decrease of the articulotrochanteric distance was mild in P2 and P4, and severe in P12 and P20. Subluxation of the femoral head was observed only in P12 and P20 piglets. INTERPRETATION:The piglet model of LCPD was useful in the early stage of devascularization for investigation of the developmental pattern of femoral head deformity. However, when the piglets had grown to 20 weeks old or more--that is, to full skeletal maturity--the femoral head and acetabulum showed severe deformities that were most likely caused by heavy body weight.
journal_name
Acta Orthopjournal_title
Acta orthopaedicaauthors
Rowe SM,Lee JJ,Chung JY,Moon ES,Song EK,Seo HYdoi
10.1080/17453670610045678keywords:
subject
Has Abstractpub_date
2006-02-01 00:00:00pages
33-8issue
1eissn
1745-3674issn
1745-3682pii
738520545journal_volume
77pub_type
杂志文章abstract::Background and purpose - The long-term effects of computer-assisted surgery in total knee replacement (CAS) compared to conventionally operated knee replacement (CON) are still not clear. We compared survivorship and relative risk of revision in CAS and CON based on data from the Norwegian Arthroplasty Register. Patie...
journal_title:Acta orthopaedica
pub_type: 杂志文章,多中心研究
doi:10.1080/17453674.2016.1244884
更新日期:2016-12-01 00:00:00
abstract::Background and purpose - The uncemented Symax hip stem has shown early proximal ingrowth as result of the BONIT-hydroxyapatite (HA) coating and the distal DOTIZE surface treatment. We evaluated 2-year postoperative radiostereometric analysis (RSA) migration of the Symax hip stem in THA patients. We also investigated t...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453674.2019.1709956
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:No prospective surveillance systems have been available for monitoring the outcome of cruciate ligament surgery in Scandinavia (Denmark, Norway, and Sweden). In the present paper we describe the Scandinavian ACL registries including their main function, similarities, and preliminary baseline resu...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453670903350107
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Few studies have been concerned with the patient's perception of the outcome of limb lengthening. We describe the psychological and social functioning after at least 2 years of follow-up in patients who had had a leg length discrepancy and who had undergone an Ilizarov limb lengthening procedure....
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453670903473024
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Fat embolism (FE), the release of bone marrow contents into the circulation and the subsequent cardiovascular changes, is still a potentially fatal com-plication during orthopedic surgery. Different causative factors have been suggested, but the exact pathomechanism of FE still remains unclear. We investigat...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670510045570
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The pathomechanics of the Essex-Lopresti lesion are not fully understood. We used human cadavers and documented the genesis of the injury with high-speed cameras. METHODS:4 formalin-fixed cadaveric specimens of human upper extremities were tested in a prototype, custom-made, drop-weight test ben...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.887952
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:The occurrence of club foot (CF) varies between countries and populations, and may be related to endogenous and exogenous factors. We analyzed the occurrence of CF in a whole country over a long period of time (16 years). METHODS:Patients born in Denmark with a foot deformity 1978-93 were identified from th...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610013114
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Deep vein thrombosis is common after total joint replacement. It is frequently asymptomatic, and it is unclear whether this leads to longer-term problems such as post-thrombotic syndrome and leg ulceration. We investigated whether the postoperative prevalence of ulceration in patients who had und...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2011.596064
更新日期:2011-08-01 00:00:00
abstract::Background and purpose - About one-fourth of hip fracture patients have cognitive impairment. We investigated whether patients' cognitive function affects surgical treatment, risk of reoperation, and mortality after hip fracture, based on data in the Norwegian Hip Fracture Register (NHFR).Patients and methods - This p...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1709712
更新日期:2020-04-01 00:00:00
abstract::Background and purpose - Several surgical approaches are used in primary total hip arthroplasty (THA). In this randomized controlled trial we compared gait, risk of fall, self-reported and clinical measurements between subjects after direct superior approach (DSA) versus posterolateral approach (PL) for THA. Patients ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1865633
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Laboratory tests and early clinical studies have shown that highly cross-linked polyethylene (PE) markedly improves wear resistance compared to conventional PE. We evaluated this type of PE in two randomized clinical studies using radiostereometric analysis (RSA). The 2- and 3-year follow-up of these studies...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453670710014518
更新日期:2007-12-01 00:00:00
abstract::Background and purpose - Up to 20% of patients are dissatisfied after total knee arthroplasty (TKA), mainly because of pain and restricted physical function. We developed a prediction model for 6-month knee range of motion, knee pain, and walking limitations in patients undergoing TKA surgery. Patients and methods - W...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2018.1560647
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cementless total hip arthroplasty is currently favored by many orthopedic surgeons. The design of the porous surface is critically important for long-term fixation. We examined the clinical and radiographic outcome of the cementless titanium hip implant with a bottom coating of apatite-wollastoni...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.736173
更新日期:2012-12-01 00:00:00
abstract::Background and purpose - Femoral neck fractures are commonly treated with cemented or uncemented hemiarthroplasties (HA). We evaluated differences in mortality and revision rates in this fragile patient group.Patients and methods - From January 1, 2007 until December 31, 2016, 22,356 HA procedures from the Dutch Arthr...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1752522
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Gamma irradiation has been widely used for sterilization of bone allografts. However, gamma irradiation alters proteins. This is favorable when it reduces immunogenicity, but is undesirable when osteoinductive proteins are damaged. Although the effect of gamma irradiation on BMPs has been studied, the effect...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610013394
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Multimodal techniques can aid early rehabilitation and discharge of patients following primary joint replacement. We hypothesized that this not only reduces the economic burden of joint replacement by reducing length of stay, but also helps in reduction of early complications. PATIENTS AND METHO...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2011.618911
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Complications related to the fibula during distraction osteogenesis could cause malalignment. Most published studies have analyzed only migration of the fibula during lengthening, with few studies examining the effects of fibular complications. PATIENTS AND METHODS:We retrospectively reviewed 12...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.665328
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Modern metal-on-metal hip resurfacing was introduced as a bone-preserving method of joint reconstruction for young and active patients; however, the large diameter of the bearing surfaces is of concern for potentially increased metal ion release. PATIENTS AND METHODS:71 patients (< 65 years old) were random...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.3109/17453674.2011.625533
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In recent years several different plate designs for internal fixation of fractures of the distal radius have been developed. However, few biomechanical studies have been performed to compare these new implants. The purpose of this study was to compare the mechanical properties of 5 different comm...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453670902947440
更新日期:2009-04-01 00:00:00
abstract::Background and purpose - The number of primary, highly constrained knee arthroplasty implants has increased with a theoretically increased risk of early failure. Therefore we analyzed the risk of all revision following total knee arthroplasty (TKA) in patients receiving a hinged or condylar constrained knee (CCK) comp...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1627638
更新日期:2019-10-01 00:00:00
abstract::Background and purpose - Hip dislocation is one of the most common complications following total hip arthroplasty (THA). Several factors that affect dislocation have been identified, including acetabular cup positioning. Optimal values for cup inclination and anteversion are debatable. We performed a systematic review...
journal_title:Acta orthopaedica
pub_type: 杂志文章,评审
doi:10.1080/17453674.2016.1251255
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several mechanisms are responsible for patellar dislocation. We investigated how the primary pathomechanism relates to patient characteristics and the outcome. METHODS:126 patients (81 females) with primary patellar dislocation reported the knee position before the episode, the movement during i...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453670903110634
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We previously evaluated a new uncemented femoral stem designed for elderly patients with a femoral neck fracture and found stable implant fixation and good clinical results up to 2 years postoperatively, despite substantial periprosthetic bone mineral loss. We now present the medium-term follow-u...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.931195
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although total ankle replacement (TAR) is a recognized procedure for treatment of the painful arthritic ankle, the best choice of implant and the long-term results are still unknown. We evaluated the survival of two TAR designs and factors associated with survival using data from the nationwide a...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453671003685459
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The reproducibility of results and potential confounders in sample-based studies is important to consider in the assessment of studies. Comprehensive arthroplasty registers could serve as a reference dataset for comparative analyses. We analyzed an implant that is frequently used worldwide, the O...
journal_title:Acta orthopaedica
pub_type: 杂志文章,评审
doi:10.3109/17453674.2011.566134
更新日期:2011-04-01 00:00:00
abstract::Background and purpose - A 2-stage revision is the most common treatment for late deep prosthesis-related infections and in all cases of septic loosening. However, there is no consensus about the optimal interval between the 2 stages. Patients and methods - We retrospectively studied 120 deep infections of total hip (...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2016.1142305
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We have previously reported that the first 10 years of hip arthroplasty in Lithuania resulted in a higher cumulative revision rate than that observed in Sweden. We thus compared the corresponding results after introduaction of total knee replacement in Lithuania. METHODS:The 10-year revision rat...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670902804984
更新日期:2009-02-01 00:00:00
abstract::Background and purpose - Patients having a total knee arthroplasty (TKA) after a previous high tibial osteotomy (HTO) constitute a minor group among those undergoing primary TKA for knee osteoarthritis (OA). There have been few reports on whether such patients differ pre- and postoperatively from those who undergo TKA...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2016.1195663
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There are no reports in the literature on the influence of learning on the pedicle screw insertion. We studied the effect of learning on the rate of screw misplacement in patients with adolescent idiopathic scoliosis treated with segmental pedicle screw fixation. METHOD:We retrospectively evalua...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2010.548032
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Substantial bone loss in revision total knee arthroplasty (TKA) is a challenging problem. We studied whether impaction bone grafting provides long-term restoration of bone stock in the treatment of major bone defects in revision surgery of rotational and hinged knee arthroplasties (LINK Endo-Mode...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2013.814012
更新日期:2013-08-01 00:00:00