Increasing incidence of club foot with higher population density: incidence and geographical variation in Denmark over a 16-year period--an epidemiological study of 936,525 births.

Abstract:

BACKGROUND:The occurrence of club foot (CF) varies between countries and populations, and may be related to endogenous and exogenous factors. We analyzed the occurrence of CF in a whole country over a long period of time (16 years). METHODS:Patients born in Denmark with a foot deformity 1978-93 were identified from the National Patient Register and the Register of Inborn Malformations. The records for each patient were studied in the hospital departments to establish the diagnoses and to obtain additional information. Demographic data were obtained from the Danish National Demographical Institute and from the Danish Population Register. RESULTS:The incidence of isolated CF was 1.2/1,000 live births. It increased significantly during the study period, and the incidence of CF and the standardized morbidity ratio for CF were significantly positively correlated to population densities in the counties and the districts. There was no significant increase in the relative proportion of children with CF born to non-Scandinavian parents during the period. INTERPRETATION:The increasing incidence of isolated CF with higher population density indicates that there may be exogenous factors that are pathogenic.

journal_name

Acta Orthop

journal_title

Acta orthopaedica

authors

Krogsgaard MR,Jensen PK,Kjaer I,Husted H,Lorentzen J,Hvass-Christensen B,Christensen SB,Larsen K,Sonne-Holm S

doi

10.1080/17453670610013114

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

839-46

issue

6

eissn

1745-3674

issn

1745-3682

pii

770235883

journal_volume

77

pub_type

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