Abstract:
BACKGROUND:Modern metal-on-metal hip resurfacing was introduced as a bone-preserving method of joint reconstruction for young and active patients; however, the large diameter of the bearing surfaces is of concern for potentially increased metal ion release. PATIENTS AND METHODS:71 patients (< 65 years old) were randomly assigned to receive either a resurfacing (R) hip arthroplasty (n = 38) or a conventional metal-on-metal (C) hip arthroplasty (n = 33). Functional outcomes were assessed preoperatively and at 6, 12, and 24 months. Cobalt and chromium blood levels were analyzed preoperatively and at 3, 6, 12, and 24 months. RESULTS:All functional outcome scores improved for both groups. At 12 and 24 months, the median UCLA activity score was 8 in the R patients and 7 in the C patients (p < 0.05). At 24 months, OHS was median 16 in C patients and 13 in R patients (p < 0.05). However, in spite of randomization, UCLA scores also appeared to be higher in R patients at baseline. Satisfaction was similar in both groups at 24 months. Cobalt concentrations were statistically significantly higher for R patients only at 3 and 6 months. Chromium levels remained significantly higher for R patients until 24 months. No pseudotumors were encountered in either group. One R patient was revised for early aseptic loosening and in 2 C patients a cup insert was exchanged for recurrent dislocation. INTERPRETATION:R patients scored higher on UCLA, OHS, and satisfaction at some time points; however, as for the UCLA, preoperative levels were already in favor of R. The differences, although statistically significant, were of minor clinical importance. Chromium blood levels were statistically significantly higher for R patients at all follow-up measurements, whereas for cobalt this was only observed up to 6 months. The true value of resurfacing hip arthroplasty over conventional metal-on-metal hip arthroplasty will be determined by longer follow-up and a possible shift of balance between their respective (dis)advantages.
journal_name
Acta Orthopjournal_title
Acta orthopaedicaauthors
Smolders JM,Hol A,Rijnberg WJ,van Susante JLdoi
10.3109/17453674.2011.625533subject
Has Abstractpub_date
2011-10-01 00:00:00pages
559-66issue
5eissn
1745-3674issn
1745-3682journal_volume
82pub_type
杂志文章,随机对照试验abstract:BACKGROUND AND PURPOSE:Monoblock acetabular cups represent a subtype of uncemented cups with the polyethylene liner molded into a metal shell, thus eliminating-or at least minimizing-potential backside wear. We hypothesized that the use of monoblock cups could reduce the incidence of osteolysis and aseptic loosening, a...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2012.688726
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Aseptic loosening is the major cause of implant failure. In cemented hip arthroplasty, failure of the acetabular side is mainly due to lysis caused by wear particles. By using an implant with low wear characteristics and by enhancing acetabular fixation using an uncemented implant, we aimed to reduce acetabu...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670710014103
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Substantial bone loss in revision total knee arthroplasty (TKA) is a challenging problem. We studied whether impaction bone grafting provides long-term restoration of bone stock in the treatment of major bone defects in revision surgery of rotational and hinged knee arthroplasties (LINK Endo-Mode...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2013.814012
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is increasing awareness that non-steroidal anti-inflammatory drugs (NSAIDs), and especially the cyclooxygenase-2 (COX-2) selective ones, may retard bone healing. We have used NSAIDs (indomethacin for at least 7 days) to prevent heterotopic ossification after acetabular reconstructions using...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670710015562
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Outcome measurement of shoulder arthroplasty is not standardized. We compared 3 scores and 1 evaluation form. PATIENTS AND METHODS:We report on 35 hemiarthroplasties of the shoulder (32 cementless). Mean age of the patients was 62 (29-87) years. After a mean follow-up of 6 years (range 2-18 years) patients ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610012980
更新日期:2006-10-01 00:00:00
abstract::Background and purpose - Hindfoot arthrodesis using retrograde intramedullary nailing assumes a critical role in limb salvage for patients with diabetic Charcot neuro-arthropathy (CN). However, this procedure is compelling and fraught with complications in diabetic patients. We report the mid-term clinical and radiolo...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1746605
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several mechanisms are responsible for patellar dislocation. We investigated how the primary pathomechanism relates to patient characteristics and the outcome. METHODS:126 patients (81 females) with primary patellar dislocation reported the knee position before the episode, the movement during i...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453670903110634
更新日期:2009-08-01 00:00:00
abstract::Background and purpose - Elderly patients may benefit from a dislocation low-risk dual-mobility (DM) articulation in total hip arthroplasty, but the best cup fixation method is unknown. We compared cup migration for cemented and cementless DM cups using radiostereometry.Patients and methods - In a patient-blinded rand...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
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更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:The etiology of osteoarthritis (OA) is multifactorial and current research attributes it to a complex network of biochemical factors. We attempted to identify important molecules in OA joint destruction. PATIENTS AND METHODS:Synovium was collected from 2 women with hip OA. Total RNA was extracted from the c...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670710014400
更新日期:2007-10-01 00:00:00
abstract::Background and purpose - The Mitch proximal epiphyseal replacement (PER) was developed to preserve proximal femoral bone and minimize femoral neck fracture associated with hip resurfacing arthroplasty (HRA). We studied the survival and risk of revision of HRA compared with cementless metal-on-polyethylene (MoP) total ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1646201
更新日期:2019-12-01 00:00:00
abstract::Background and purpose - A risk-stratification algorithm for metal-on-metal hip arthroplasty (MoMHA) patients was devised by US experts to help clinicians make management decisions. However, the proposed algorithm did not cover all potential patient or surgical abnormalities. Therefore we adapted the US risk-stratific...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1659661
更新日期:2019-12-01 00:00:00
abstract::Perspective Orthopaedic training in the United Kingdom has changed little from the Halstedian apprenticeship model of graduated responsibility, with the mantra "see one, do one, teach one". Whilst still relevant in surgical teaching, the current and ongoing disruption to surgical training secondary to the coronavirus ...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2020.1845437
更新日期:2020-11-11 00:00:00
abstract::Background and purpose - Although the results of primary total hip replacements (THRs) are generally excellent, sometimes serious complications arise. Some of these severe complications are considered to be patient injuries. We analyzed primary THR-related patient injuries in a nationwide setting. Patients and methods...
journal_title:Acta orthopaedica
pub_type: 评论,杂志文章
doi:10.3109/17453674.2015.1135662
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Gamma irradiation has been widely used for sterilization of bone allografts. However, gamma irradiation alters proteins. This is favorable when it reduces immunogenicity, but is undesirable when osteoinductive proteins are damaged. Although the effect of gamma irradiation on BMPs has been studied, the effect...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610013394
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Hospital volume has been suggested to be one of the best indicators of adverse orthopedic events in patients undergoing THR surgery. We therefore evaluated the effect of hospital volume on the length of stay, re-admissions, and complications of THR at the population level in Finland. METHODS:30,...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2010.533930
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Extracorporeal shock wave treatment has been used successfully for the treatment of avascular necrosis of the femoral head. The pathway of biological events by which this is accomplished has not been fully elucidated. BMP-2 is a key mediator of bone development and repair, and is uniquely require...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670710014833
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Periacetabular osteotomy improves radiographic predictors of osteoarthrosis and diminishes pain and functional impairment. No changes in function quantified by gait analysis have yet been documented. We evaluated the functional outcome of periacetabular osteotomy in relation to gait. METHODS:The gait patter...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610045920
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Integration of repaired cartilage with surrounding native cartilage is a major challenge for successful tissue-engineering strategies of cartilage repair. We investigated whether incorporation of mesenchymal stem cells (MSCs) into the collagen scaffold improves integration and repair of cartilage...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.958807
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We have previously shown that early fracture callus of rat rib has viscoelastic and contractile properties resembling those of smooth muscle. The cells responsible for this contractility have been hypothesized to be myofibroblast-like in nature. In soft-tissue healing, force generated by contract...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2011.652891
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Laboratory tests and early clinical studies have shown that highly cross-linked polyethylene (PE) markedly improves wear resistance compared to conventional PE. We evaluated this type of PE in two randomized clinical studies using radiostereometric analysis (RSA). The 2- and 3-year follow-up of these studies...
journal_title:Acta orthopaedica
pub_type: 杂志文章,随机对照试验
doi:10.1080/17453670710014518
更新日期:2007-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Cyclooxigenase-2 (COX-2) inhibitors have been reported to delay fracture healing. To investigate the major inhibitory period of COX-2 inhibitors in fracture healing, we administrated etodolac, a COX-2-specific inhibitor, to a rat fracture model by altering the period of administration from early to late. ME...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670510041439
更新日期:2005-08-01 00:00:00
abstract::Background and purpose - There is a general call for phased introduction of new implants, and one step in the introduction is an early evaluation of micromotion. We compared the micromotion in the Triathlon and its predecessor, the Duracon total knee prosthesis, concentrating especially on continuous migration over 5 ...
journal_title:Acta orthopaedica
pub_type: 评论,杂志文章
doi:10.3109/17453674.2016.1166876
更新日期:2016-06-01 00:00:00
abstract::Background and purpose - Up to 20% of patients are dissatisfied after total knee arthroplasty (TKA), mainly because of pain and restricted physical function. We developed a prediction model for 6-month knee range of motion, knee pain, and walking limitations in patients undergoing TKA surgery. Patients and methods - W...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2018.1560647
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:In some countries, commercially available antibiotic powder-loaded acrylic bone cement is routinely used in joint replacement, while, in others, "off-label" formulations are used in selected procedures (where the antibiotic powder is blended manually with the powder of a plain cement in the operating room/th...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453670610012700
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Surgical treatment of chronic acromioclavicular joint dislocations is challenging, and no single procedure can be considered to be the gold standard. In 2010, the GraftRope method (Arthrex Inc., Naples, FL) was introduced in a case series of 10 patients, showing good clinical results and no compl...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2014.976806
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is continuing confusion among practitioners with regard to the optimal choice of anesthetic type for repair of hip fractures. We investigated whether type of anesthetic was associated with short-term mortality after hip fracture surgery. PATIENTS AND METHODS:We conducted a retrospective co...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2015.1128781
更新日期:2016-01-01 00:00:00
abstract::Background and purpose - The number of primary, highly constrained knee arthroplasty implants has increased with a theoretically increased risk of early failure. Therefore we analyzed the risk of all revision following total knee arthroplasty (TKA) in patients receiving a hinged or condylar constrained knee (CCK) comp...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.1080/17453674.2019.1627638
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Intraoperative periprosthetic femoral fracture is a known complication of cementless total hip arthroplasty (THA). We determined the incidence of--and risk factors for--intraoperative calcar fracture, and assessed its influence on the risk of revision. PATIENTS AND METHODS:This retrospective ana...
journal_title:Acta orthopaedica
pub_type: 杂志文章
doi:10.3109/17453674.2015.1112712
更新日期:2016-01-01 00:00:00
abstract::- The International Society of Arthroplasty Registries (ISAR) Patient-Reported Outcome Measures (PROMs) Working Group have evaluated and recommended best practices in the selection, administration, and interpretation of PROMs for hip and knee arthroplasty registries. The 2 generic PROMs in common use are the Short For...
journal_title:Acta orthopaedica
pub_type: 评论,杂志文章
doi:10.1080/17453674.2016.1181816
更新日期:2016-07-01 00:00:00